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曺東震,韓俊澤,劉憲一,朴龍鎭,金錫胤,慶在浩 弘益大學校 1974 弘大論叢 Vol.6 No.-
The matrix of ductile cast iron are welded by pre-heating it at 300℃ in the room temperature. Through the mechanical, non-desbructive testing and analysis of the composition. the possibility if arc welding of ductile cast iron are studied as follows; 1. L electrode is the best among them in weldability, impact value and machinability. The next is LB electrode followed by S electrode. C electrode is last. However, the tensile strength showed in the following order: LB, S, L, C. 2. LB, S, L, C, all are available for the welding of cast iron. 3. The above experiment showed that L and LB are good in general. In addition LB is low in price, we therefore prospect that it will be widely used as the electrode for cast iron.
崔宗煐,李定均,徐維憲,朴贊雄 大韓神經精神醫學會 1981 신경정신의학 Vol.20 No.1
Plasma chlorpromazine level and some aspects of the clinical significane were studied with 20 schizophrenics. The results were as follows; The (so-called) steady state of plasma chlorpromanzine level was arrived at about 12th day of the drug administration in a dose of 300mg/day on a fixed maintenane regimen. Thereafter the level tended to decline slightly. After arriving at the steady state, a significant positive correlation was observed between the plasma level and the dose of the drug, both in intra-and interpatient comparisons (r=+0.5855, p<0.025). On a fixed chlopromazine dosage, the plasma levels showed marked interpatient differences both before and after the initial day of the steady state, though the differences were more marked before the period of steady state. No significant positive correlation could be identified between the plasma level and the drug side reaction, though 78% of the observed side reactions were positively related with the plasma level of 1.5 mcg/ml or above. And again, significant positive correlation was not observed between the plasma level and the clinical improvement. So-called 'therapeutic window' was considerably wide ranging between 0.5 to 2.45 mcg/ml of the plasma level.
Yoo, Heon Jong,Lim, Myong Cheol,Lim, Soyi,Park, Jeong-Yeol,Kang, Sokbom,Park, Sang-Yoon,Seo, Sang-Soo Springer International 2012 Archives of gynecology and obstetrics Vol.286 No.6
<P>To evaluate the efficacy and toxicity of combined paclitaxel and carboplatin treatment for persistent or recurrent uterine sarcoma.</P>
Yoo, Heon Jong,Joo, Jungnam,Seo, Sang-Soo,Kang, Sokbom,Yoo, Chong Woo,Park, Sang-Yoon,Lim, Myong Cheol BMJ 2012 International journal of gynecological cancer Vol.22 No.2
<P>The purpose of the study was to investigate the relationship between body mass index (BMI) and hereditary nonpolyposis colorectal cancer (HNPCC) in Korean women with endometrial cancer.</P>
Yoo Heon Park,Bok Kyung Han,Hyeon Son Choi,Yang Hee Hong,Eun Young Jung,Hyung Joo Suh 한국축산식품학회 2015 한국축산식품학회지 Vol.35 No.2
The objective of this study was to evaluated the photoprotective effects of porcine placenta extract (PPE) on ultraviolet B (UVB)-induced oxidative stress in human keratinocytes (HaCaT) to evaluate its functional activities as a skin food ingredient. PPE prepared by subcritical water extraction was termed SPE, and subsequently digested by enzymes to prepare E-SPE. Increased intracellular reactive oxygen species (ROS) levels (192.0%) induced by UVB were decreased by SPE and E-SPE. SPE had more effective ROS scavenging activity than E-SPE treatment. UVB treatment increased expression of tissue inhibitor of metalloproteinase 1 (TIMP-1), and this elevated expression was decreased by E-SPE treatment. High-dose treatment with E-SPE (50 and 100 μg/mL) reduced TIMP-1 expression levels of UVB-C (control) to 33.5 and 34.6%, respectively. In contrast, at low SPE doses (1 and 10 μg/mL), the treatment slightly decreased TIMP- 1 expression levels to 73.3% and 71.3% of UVB-C, respectively. In conclusion, the present study demonstrated the protective effect of SPE and E-SPE against UVB damage in keratinocytes via ROS scavenging, down-regulating MMP-2 expression and up-regulating TIMP- 1 expression. This highlights the potential for SPE as an ingredient in the preparation of functional food against photoaging.
Do Joong Park,Sena An,Young Suk Park,Joo-Ho Lee,Hyuk-Joon Lee,Tae Kyung Ha,Yong-Jin Kim,Seung-Wan Ryu,Sang-Moon Han,Moon-Won Yoo,Sungsoo Park,Sang-Uk Han,Jae-Heon Kang,Jin-Won Kwon,Yoonseok Heo 대한외과학회 2021 Annals of Surgical Treatment and Research(ASRT) Vol.101 No.4
Purpose: The aim of this study was to show that bariatric surgery (BS) is more effective than medical therapy (MT) in Asian obese patients. Methods: In this prospective, multicenter, nonrandomized, controlled trial, obese patients with body mass index of ≥35 kg/㎡ or 30.0–34.9 kg/㎡ with obesity-related comorbidities were assigned to undergo BS, such as laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass, or MT. Patients who underwent BS were evaluated 4, 12, 24, and 48 weeks after surgery, whereas patients who received MT were monitored at a hospital every 6 weeks for 1 year. At each visit, weight, waist and hip circumference, and blood pressure were measured, and patients underwent physical examination and laboratory testing. Health-related quality of life (HQOL) was investigated using Euro QOL-5 Dimension, Impact of Weight on Quality of Life questionnaire-Lite and Obesity-related Problems scale. Results: The study included 264 patients from 13 institutions; of these, 64 underwent BS and 200 received MT. Of the patients who underwent BS, 6.3% experienced early complications. Relative weight changes from baseline to 48 weeks were significantly greater in the BS than in the MT group (26.9% vs. 2.1%, P < 0.001), as were the rates of remission of diabetes (47.8% vs. 16.7%, P = 0.014), hypertension (60.0% vs. 26.1%, P < 0.001), and dyslipidemia (63.2% vs. 22.0%, P < 0.001). HQOL was better in the BS than in the MT group at 48 weeks. Conclusion: BS was safe and effective in Korean obese patients, with greater weight reduction, remission of comorbidities, and quality of life improvement than MT.
S-331 Low Intake of Vitamin C is Significantly Associated with Chronic Obstructive Pulmonary Disease
( Seong Han Kim ),( Jae Yeol Kim ),( Jae-woo Jung ),( In-won Park ),( Yu-il Kim ),( Kwang-ha Yoo ),( Eun Mi Chun ),( Ji Ye Jung ),( Young Sik Park ),( Ju-heon Park ),( Chul Min Ahn ),( Hye Jung Park ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1
Background: Vitamin C, as a antioxidant, has been recently suggested to be associated with chronic obstructive pulmonary disease (COPD). Large cohort study about the association of vitamin C with COPD independent of smoking history is needed. Methods: We analyzed the data of 5,592 subjects who answered to questions about smoking history, with stratification variables and sampling weight designated by the Korea 2012 National Health and Nutrition Examination Survey. Results: Heavier smoking history was associated with male, old age, Eup/Myun residence, general type of residence, low household income, low level of education, and occupation. The concentration of Pb and Hg was significantly higher in heavy smokers (3.6 and 6.6, respectively) than that in never smokers (2.2 and 4.0, respectively) (<0.001 in both of them). In COPD subjects, amount of food, kalium, vitamin, carotene, and retinol intake was significantly lower than that in non-COPD subjects. The amount of vitamin C intake (mg) was significantly lower in COPD (93.2±3.9) than that in non-COPD (122.1±4.0) (p<0.001). In multivariate analysis, sex, age, smoking history, and amount of vitamin C intake was independent and significant risk factors for COPD. In heavy smoker, prevalence of COPD in lowers quartile of vitamin C intake (63.0%) was significantly higher than that in upper middle quartile of vitamin C intake (29.5%) (p=0.015), (Fig. 1). Conclusions: Low intake of vitamin C is a significant risk factor for COPD independent of smoking history.
Park, Young-Kil,Lee, Seung-Heon,Kim, Su-Young,Ryoo, Sung-Weon,Kim, Chang-Ki,Kim, Hee-Jin,Cho, Eun-Hee,Yoo, Byung-Hee,Lee, Jong-Koo,Ko, Won-Jung The Korean Academy of Tuberculosis and Respiratory 2010 Tuberculosis and Respiratory Diseases Vol.68 No.6
Background: There are several active tuberculosis (TB) cases in Korean high schools each school year. The risk of transmission in schools is extremely high due to the considerable time spent in closed classrooms. We evaluated the control of latent tuberculosis infection in Korean high schools. Methods: When a student was identified with active TB, tuberculin skin testing was performed on their classmates and on students in their same school grade. When a student had a positive tuberculin skin tests (TST), they underwent follow-up testing with QuantiFERON-TB Gold In-Tube (QFT). The manufacturer recommended a cut-off of 0.35 IU/mL to determine QFT positivity was applied. Results: A total of 131 pulmonary tuberculosis (TB) patients were included based on the criteria for screening TB contacts in the National Tuberculosis Control Program. Seventy-five (57.2%) students tested smear positive. TST were performed on 7,109 students who were classmates of, or in the same grade as, a TB patient. Of the contacts, 1,231 students (17.3%) were TST positive and they were screened with QFT. Six hundred-sixty-six (55.0%) of the tested students returned a positive QFT result and the rate of positivity was significantly associated with the increasing size of TST indurations (p<0.0001). Conclusion: The use of QFT resulted in approximately 45% of TST positive students not being given chemoprophylaxis.