외상에 의한 지연성 뇌경색 2예 : Case Reports

김수일,김헌주,한용표,홍순기,허철 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.5

Delayed traumatic cerebral infarction appears to occur more frequently than previously expected. We have experienced two cases of this clinical entity whose initial neurological condition were good except headache and/or mental confusion. However, their initial Brain CT scans showed no specific abnormalities. The detailed neurological examination and follow up Brain CT scans were prerequisite choices of strategy against this type of lesion. However, additional studies regarding intracranial pressure(ICP), cerebral blood flow(CBF), multimodality evoked potential(MMEP) and magnetic resonance imaging(MRI) should be considered as an alternative armamentarium for further elucidation of vascular insults to already injured brain.

뇌종양의 악성도 판정을 위한 분열기 세포측정에 관한 연구

한용표,변진수,허철,홍순기,김헌주,조미연,정순희,김호근 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.11

Tissue markers of cellular proliferation have been utilized as prognostic indicators in tumors of the central nervous system. Nucleolar organizer regions represent transcriptionally active sites of ribosomal deoxyribonucleic acid and can be identified by a simple argyrophilic technique. The authors describe a standardized approach to the assessment of these argyrophilic nucleolar organizer regions(AgNORs) in 25 astrocytomas(including 6 glioblastomas), 6 oligodendrogliomas and 1 xanthochromic astrocytoma, which were also estimated in association with 2-year survival post-operatively. Appropriate sections were silver stained and AgNORs were counted in 1000 cells. In cases of astrocytoma, the mean AgNORs/cell count of group survived more than 2 years after operation was significantly different from that survived less than 2 years : 1.93±1.13 vs. ≥ 4.79±3.90. And the mean AgNORs/cell count was 1.53±0.32 in low grade astrocytoma. 2.03±0.59 in grade Ⅲ astrocytoma, and ≥6.64±3.77 in grade Ⅳ astrocytoma. Among the patients with the same grade astrocytoma, the mean AgNORs/cell count was lower in the cases of long survival rather than short survival. The assessment of AgNORs can be easily performed by any surgical pathology laboratory without specialized equipment. It may be used as a valuable and independent prognosticator of biological behavior in cases of astrocytoma.

수도권에서 아황산가스의 황산염으로 전환시 각 과정의 상대적 기여도

배수야,김용표 한국대기환경학회 2003 한국대기환경학회지 Vol.19 No.4

The major conversion processes of SO₂ to sulfate arc reactions in gaseous, aqueous phase and on dust surface. Using the measurement data in Ganghwa, the background area of metropolitan Seoul Area, the relative contiribution of the conversion processes am estimated. Generally, aqueous cloud is the most important conversion path followed by dust surface. gas, and aqueous aerosol. Importance of conversion on dust surface increases for the dust storm period. The total conversion rate values over the metropolitan Seoul area are between 1.5 and 8.8×10^(-11) mole m_(-3) air.

디젤분진이 사람 동맥 평활근 세포(VSMC)에 미치는 영향

임용,김수연,정규혁,정진호,문창규,윤여표 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.1

The purpose of the present study was to examine the effect of diesel exhaust particles on human aortic vascular smooth muscle cells(VSMCs). DNA synthesis, cell viability and morphology of VSMCs after treatment of diesel exhaust particles(DEP) and fine particulate matter(PM_(2.5)) were assayed. PM_(2.5) inhibited the DNA synthesis of VSMCs in a concentration-dependent manner, whereas DEP did not affect VSMCs up to 50㎍/mL . These results were confirmed by morphological examination of VSMCs. PM_(2.5) showed a dose-dependent cytotoxicity of VSMCs by MTT assay. Fraction 4(organic acids) and fraction8(moderately polar compounds) showed the most potent inhibition of DNA synthesis of VSMCs, and fraction7(slightly polar compounds), fraction9(higher polar compounds), and fraction6(aromatic compounds) were next order. These results were confirmed by morphological examination of VSMCs. These results suggest that PM_(2.5) inhibits the DAN synthesis of VSMCs through the cytotoxicity.

두부손상시 발견된 뇌혈관질환

윤승환,변진수,홍순기,김헌주,한용표 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.10

Five separate incidences of patients with cerebrovascular disease(CVD) were revealed among 555 craniocerebral traumatic victims between 1991 and 1992. The 5 cases of with cerebrovascular disease revealed included 3 aneuryms. 1 arteriovenous malformation and 1 spontaneous intracerebral hematoma caused by angiographic study. The frequent use of computerized tomographic scans in the evaluation of head-injured victims can well demonstrate an intracerebral hemmorrhage, but may not get able to direct the associated cerebrovascular disease;whereas the efficacy of angiography, on the contrary, has been losing its popularity as diagnostic armamentarium. The importance of angiographic study should be considered, if clinical signs and/or brain CT ideate the possibility of cerebrovasular disease even during the course of head injury management.

외상성 뇌실출혈의 임상적 분석

김호진,변진수,허철,홍순기,김헌주,한용표 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.2

Intraventricular hemorrhage after blunt head trauma, which reflects the severity of head injury, is uncommon. A retrospective study of 109 traumatic intraventricular hemorrhage(TIVH) patients who were admitted between January 1, 1988 and December 31, 1993 was conducted. The results are as follows : 1) Incidence of TIVH and its associated mortality were 2.45% and 28.4%, respectively. 2) TIVH-associated radiological abnormalities were traumatic intracerebral hematoma(62.7%), skull fracture(42.7%), and traumatic subarachnoid hemorrhage(34.5%). 3) Amount of TIVH was related to traumatic intracerebral hematoma(p=0.0003) and traumatic subarachnod hemorrhage(p=0.0385). 4) The poorest prognostic indicator was associated abnormalities, especially corpus callosum or brainstem hemorrhage(p=0.0099). 5) TIVH-associated hydrocephalus was not related to the amount of TIVH(p=0.42), and poor prognosis(p=0.12). 6) Patients with TIVH showed better Glasgow coma scale and Glasgow outcome scale than TIVH-associated abnormalities.

소뇌에 발생한 과립구성 육종 : 증례보고

윤승환,변진수,홍순기,김헌주,한용표,양재승,조미연 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.8

Granulocytic sarcoma, a rare extramedullary solid tumor arising from early myeloid precursors, is capable of invading the meninges or the brain parenchyma. The tumor may occur during or after the onset of systemic myelogenous leukemia. On rare occasions, the tumor may evolve before the onset of systemic myelogenous leukemia. Children are affected more often than adults, but sex is not related. Although no definite target area of the brain can be demonstrated, there may be some predilection of the tumor for the posterior fossa. The authors report a case of 4-year-old-boy with granulocytic sarcoma occuring in the posterior fossa presenting with gait disturbance and torticollis. The patient was treated by surgical removal of the tumor, thereby avoiding the potentially lethal complication of a posterior fassa mass. This rare case is reported together a review of the literature.

급성기 두부손상환자시 알콜이 Creatine Kinase-BB(CK-BB)에 미치는 영향

김헌주,변진수,허철,홍순기,한용표 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.9

Patients suffering a head-injury were often drinking alcohol shortly before the trauma, and it has been suggested that the degree of brain damage may be exacerbated due to high alcohol serum levels. To evaluate this, we assessed the level of consciousness, alcohol and creatinine Kinase-bb(CK-BB) serum levels in 140 consecutive head-injured patients. Level of consciousness(GCS score) was strongly correlated to outcome(p<0.001) and serum CK-BB(P<0.05), but not to alcohol serum levels.

취학전 아동의 체력 실태와 평가

권영옥,김동권,민춘기,이용인,전종귀,진윤수,홍성표 忠南大學校體育科學硏究所 1995 體育科學硏究誌 Vol.13 No.1

The purpose of this study was analyze children's Physical Fitness and basic rate by observing the change in the heart rate of the 1230 children of five of six years of age. Following conclusions were obtained The muscular strength was relatively low according to places. And the muscular strength of boys was higher than that of girls. The flexibility of girls was higher than that of boys according to places and sexes. The muscular endurance, power, balance and agility of boys were higher than those of girls according to places and sexes. Thus the development of physical fitness was improved with their ages, the physical fitness for physique seemed rather low. So the programs of physical plays for children's physical fitness ought to be developed and physical play showed to be done at kindergarten school.

신경피부멜라닌증 환자의 두개강내에 발생한 원발성 악성 흑색종 : Case Report

노재섭,황금,한용표,김헌주,홍순기,허철,변진수 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.10

An unusual case of neurocutaneous melanosis is presented. The patient had congenital dermal nevi, and displayed multicentric malignant cerebral melanoma associated with hydrocephalus and seizure in adult life. This suggests that a patient with congenital dermal nevus or marked generalized cutaneous pigmentation should be closely observed for the development of malignant melanoma of the nervous system.