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( Xinji Tian ),( Qianqian Li ),( Xingwang Li ),( Hui Zhang ),( Khaled Rabie ),( Charles Casimiro Cavalcante ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.11
In this paper, we consider a two-way relay non-orthogonal multiple access (TWR-NOMA) system with residual hardware impairments (RHIs) and channel estimation errors (CEEs), where two group users exchange their information via the decode-and-forward (DF) relay by using NOMA protocol. To evaluate the performance of the considered system, exact analytical expressions for the outage probability of the two groups users are derived in closed-form. Moreover, the asymptotic outage behavior in the high signal-to-noise ratio (SNR) regime is examined and the diversity order is derived and discussed. Numerical simulation results verify the accuracy of theoretical analyses, and show that: i) RHIs and CEEs have a deleterious effects on the outage probabilities; ii) CEEs have significant effects on the performance of the near user; iii) Due to the RHIs, CEEs, inter-group interference and intra-group interference, there exists error floors for the outage probability.
( Yang Liu ),( Yifeng Li ),( Xinjie Yu ),( Leilei Yu ),( Fengwei Tian ),( Jianxin Zhao ),( Hao Zhang ),( Qixiao Zhai ),( Wei Chen ) 한국미생물생명공학회(구 한국산업미생물학회) 2021 Journal of microbiology and biotechnology Vol.31 No.1
Lactobacillus casei, one of the most widely used probiotics, has been reported to alleviate multiple diseases. However, the effects of this species on intestinal diseases are strain-specific. Here, we aimed to screen L. casei strains with inflammatory bowel disease (IBD)-alleviating effects based on in vitro physiological characteristics. Therefore, the physiological characteristics of 29 L. casei strains were determined, including gastrointestinal transit tolerance, oligosaccharide fermentation, HT-29 cell adhesion, generation time, exopolysaccharide production, acetic acid production, and conjugated linoleic acid synthesis. The effects of five candidate strains on mice with induced colitis were also evaluated. The results showed that among all tested L. casei strains, only Lactobacillus casei M2S01 effectively relieved colitis. This strain recovered body weight, restored disease activity index score, and promoted anti-inflammatory cytokine expression. Gut microbiota sequencing showed that L. casei M2S01 restored a healthy gut microbiome composition. The western blotting showed that the alleviating effects of L. casei M2S01 on IBD were related to the inhibition of the NF-κB pathway. A good gastrointestinal tolerance ability may be one of the prerequisites for the IBD-alleviating effects of L. casei. Our results verified the efficacy of L. casei in alleviating IBD and lay the foundation for the rapid screening of L. casei strain with IBD-alleviating effects.