한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

A Basic Study on Leaf and Stem Production of Angelica acutiloba

Choi,Seong-Kyu,Yun,Kyeong-won,Chon,Sang-Uk,Lee,Jong-Ill,Seo,Young-Nam,Seo,Kyoung-Sun,Choi,Kyeong-Ju 한국자원식물학회 2004 Plant Resources Vol.7 No.3

This study was conducted to develop effective production system in greenhouse for leaves and stems of Angelica acutiloba by using connect pots in 2003 and 2004. Seed germination rate and plant biomass of Angelica acutiloba collected in 2004 were higher than those harvested in 2003. Germination rate of Angelica acutiloba seeds collected in 2003 was 10%, while germination rate of seeds collected in 2004 was above 90%. Especially, plant growth and yield of Angelica acutiloba grown in connect pots sized with 4×4×5cm(length×width×height) were the highest. These results indicate that leaf and stem production of Angelica acutiloba can be improved by using connect pots and optimizing seed collecting time in greenhouse.

주요우울증이 근로자의 생산성에 미치는 영향 : WHO-HPQ(Health and Work Performance Questionnaire)를 이용한 예비연구

김원,황태연,함병주,이준석,최병휘,김세주,서용진,강은호,우종민 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

Objectives : Major depressive disorder (MDD) causes patients' distress and makes socioeconomic burden, both directly and indirectly. We used the concept of lost productive time (LPT) to estimate the indirect costs and calculated both absenteeism and presenteeism among workers with MDD. Mcthods : Depression group was recruited from workers visiting psychiatric outpatient clinic who had MDD without major physical or mental disorders (N= 106). Age and sex matched healthy control group was also recruited through advertisement (M=100). All participants completed a interview using WHO Health and Work Performance Questionnaire (HPQ), Job Stress Measurement Scale for Korean Employees, and Hamilton Rating Scale for Depression. Statistical analysis was performed with independent t-test or χ² test as characteristics of values (p=0.05). Results : The number of absence (0.94-day/month vs. 0.10-day/month, P=0.015) andthe numberofearly leaving (2.56-day/month vs. 0.24-day/month, P<0.001) were significantly higher in the depression group. Depression group evaluated their Perfor-mance level much lower than controls with significant value (5.16 vs. 7.62, P<0.001). In addition, depression group estimated their performance level during the last 4 weeks lower compared to the level of past 1-year (5.16 vs 6.63, P<0.001). The estimated costs of absenteeism in depression group were higher than controls by 2,520,000 Korean Won per year, and those of presenteeism were also higher by 4,880,000 Korean Won per year. The total costs of LPT in depression group were higher than controls by 7,400,000 Korean Won, which corresponds to 26% ofmean annual salary. In addition, the level of occupational stress, such as high demand and interpersonal conflict, was higher in the depression group. Conclusion : Major depressive disorder costs substantial productivity loss to workers and their company. Presenteeism imposes more time cost than absenteeism. Effectiveness trials are needed to devise cost-effective programs for the early detection and treatment of depression at the workplace.

데이터 마이닝을 활용한 한국 프로야구 구단의 승패예측과 승률 향상을 위한 전략 도출 연구

김원종 ( Kim Won-jong ),최연식 ( Choi Yeon-sik ),유동희 ( Yoo Dong-hee ) 한국스포츠산업경영학회 2018 한국스포츠산업경영학회지 Vol.23 No.3

본 연구에서는 데이터 마이닝 기법을 활용하여 한국 프로야구의 승패예측모형을 구축하는 실험을 진행하였다. 이를 위해, 2017년에 실시된 한국 프로야구 10개 구단의 전체 경기 중 무승부 경기를 제외한 1,418경기에 대한 자료를 사용하였다. 승패예측모형에는 의사결정나무, 베이즈넷, 인공신경망 알고리즘과 앙상블 기법인 배깅과 부스팅이 사용되었으며, 그 결과 배깅 기법에 인공신경망을 적용한 예측모형에서 가장 높은 예측률인 85.18%를 기록하였다. 다음으로 의사결정나무 기반 예측모형을 활용하여 한국 프로야구 전체 구단에 관한 8개의 승패규칙을 도출하였다. 여기에서 승패규칙은 승패예측에 영향을 미치는 주요 요인들인 팀출루율, 팀타율, 피안타, 안타, 타석, 타수로 표현되며, 도출된 규칙을 바탕으로 구단의 승률 향상에 도움을 주는 전략을 제안하였다. 또한 플레이오프 진출 구단과 미진출 구단에 관한 승리규칙을 각각 4개씩 도출하였고 이를 바탕으로 두 집단에 맞춤화된 승률 향상 전략을 제시하였으며, 실제 구단에서 선수를 영입한 방향과의 비교를 통해 제시된 전략의 활용 가능성을 확인하였다. This study conducted an experiment to develop win-loss prediction models for the Korean professional baseball league using data mining techniques. To this end, we used data on 1,418 games from all games played by the ten Korean professional baseball teams in 2017, except draw games. We developed win-loss prediction models using not only a decision tree, Bayse net, and artificial neural network algorithms, but also ensemble methods, such as bagging and boosting. As a result, first, we found that the artificial neural network-based prediction model using the bagging method reported the best accuracy (85.18%). Second, we derived eight win-loss rules for entire teams from the decision tree-based prediction model. These rules consist of six influential factors: team on base average, team batting average, hit by opponent, hit, plate appearances, and at bat. Using the derived rules, we proposed helpful strategies for improving the winning rate. Third, we derived four winning rules for both playoff teams and non-playoff teams; using the rules we proposed customized strategies for improving the winning rate of the two different groups. Finally, we confirmed the feasibility of the proposed strategies by comparing non-playoff teams’ actual player recruitment strategies.

GG-38 : Minimal invasive surgery (LESS) for huge cystic adnexal tumors in whole abdomen

( In Young Choi ),( Ji Hye Lee ),( Mi Hyun Park ),( Ji Kwoun Park ),( Jeong Kyu Shin1 ),( Won Jun Choi1 ),( Soon Ae Lee ),( Jong Hak Lee ),( Won Young Paik ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

Laparoendoscopic single-site surgery (LESS) is helpful if not an evidence of suspicious malignancy in huge adnexa tumors. This approach might be reasonable alternative to conventional laparoscopic surgery. We report two cases with LESS for huge cystic adnexal tumors in whole abdomen. A 58 years old multigravida woman in menopause underwent removal of a huge cystic adnexal mass that occupied her entire abdomen by LESS.(ca.5200ml aspiration) A 15 years old single nulligravida woman had a huge cystic adnexal tumor in whole abdomen reaching to the level of the xyphoid process. A needle through the transumbilical single port was inserted directly under the mass. Subsequently, 8000 ml of cystic fluid was aspirated without spillage.

백서 척수후근절로부터 슈반세포의 효과적인 체외 배양법

김성민,이종호,김남열,안강민,최원재,최시호,차미주,이주영,황순정,장정원,명훈,최진영,서병무,정필훈,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4

Schwann cells(SCs), an important component of the peripheral nervous system, intract with nerous to mutually support growth and replication for the peripheral nerve regentation. Recently, ading SCs to the lumen of guidance channel is widely tried to improve regeneration or to make regeneration possible over otherwise irreparable gaps. however, it is not easy to isolate and multiplicate SCs as much as enough to help the axonal regeneration. For the allogeneic SCs source for tubular nerve guidance, we developed a little bit improved technique of harvesting and multiplicating SCs. by culturing dispersed dorsal root ganglia in specially designed medium with growth factors and serial processing, we repeatedlly generate relatively homogenous SC cultures. Our technique was compared with other methods of literature using immunostaining methods such as GFAP, S100, BDNF and the total SC count assessment at different time interval after primary culture.

Plasminogen kringle (angiostatin) 분획의 유효부분 분석

최영기,서원덕,이종수,신광순,김철중 충남대학교 수의과대학 동물의과학연구소 1998 動物醫科學硏究誌 Vol.6 No.-

In order to inhibit the growth of the malignant tumor, the development of various drugs against the malignant tumors has been archived. The combination of these drugs made the tumor therapy possible, but in many cases, secondary matastasis of the tumor to the other organs after its removal has been frequently reported. The angiostain, recently purified and cloned, not only promtes the angiogenesis of the tumor itself in the primary tumor but also inhibits the angiogenesis and metastasis of the secondary tumors. In this study, the nucleic acid sequences of the angiostatin was investigated. And the angiostain gene was expressed in a prokayotic expression system(E. coli) and a eukayotic expression system(Pichia pastoris). The angiostain gene was futher subcloned into 6 clones to characterize its biological activity. In the near future the biological activity and the biochemical property of the protein encoded by each clone will be elucidated.

춘천 중도 선사유적 발굴조사 연구 : 고인돌을 중심으로;Concentrated on the Dolmen Site

최복규,원영환,손승철,신종원 江原大學校 江原文化硏究所 1983 강원문화연구 Vol.3 No.-

The Joong-do prehistoric site is located in the Lake of ?am dam of Chuncheon City, the capital of Kangweon province situated on the confluence of the North Han River and the Soyang River. This island site, it is washed away by the differance between the rise and fall of the lake water level, every year since 1967. The appoximate locations of Joong-do site is at 37℃ 52′;northern latitude, and 127℃ 51′ eastern longitude. The elevation of the present cultivation area is appoximately 80 meter above sea-level. This prehistoric sites, possibly ranges from Neolithic and Bronze Age to early lron Age, was brought to light in the consecutive excavations and surveys from 1981 to 1983 by the Institute of Kangweon Community Culture and the Museum of Kangweon National University. Some dolmens and ancient tombs (stone mounded), various stone tools, potteries and other relics of Neolithic, Bronze Age and early Iron Age were discovered by survey work of our excavation team from the surface and disturbed areas in the island site since 1981. During the excavation work from November 2 to December 1 in 1983, we were excavated a dolmen at center in the inland. The dolmen have four pieces of stone slab were used to make an oblong chamber covered by a large flat top stone of triangular form(size;270×196×40㎝, weight;3 ton). Both the top stone and the stone chamber surrounded by stone mounds for burial is buried under the surface. Three stone slabs of chamber coffin are required to support, but rest one inverse trapezoid stone slab of westward was not to support the top stone. The subsistance of unsupported stone slab suggested the existence of a stone chamber of which one side is open. We presumed the open side was used as a door of stone coffin. The bottom of the stone coffin under top stone was made by means of small pebble stones and large pebble stone slabs from the adjacent river beds. Size of stone slabs of coffin is at 191×94×13㎝;southern, 171×81×13㎝;northern, 80×72×9㎝;eastern. It seems, however, chronology of the dolmen are comparable to the later period of the plain coarse pottery culture(B.C.3~2C) in late Bronze Age.

세탄가를 向土시킨 LPG 戰料의 壓縮着火 디젤 엔진의 性能및 排出가스 特性에 關한 硏究

崔源歸,柳鍾植,車京玉 明知大學校 産業技術硏究所 2009 産業技術硏究所論文集 Vol.28 No.-

In this study, a feasibility test of liquefied petroleum gas (LPG) direct injection (DI) compression ignition engine has been carried out to study the effectiveness of cetane enhancing additive; Di-tertiary-butyl peroxide(DTBP) Performance and emissions characteristics of a diesel engine fuelled with LPG and DTBP blended fuel were examined Results showed that stable diesel engine operation over a wide range of the engine loads was possible. Estimated cetane number of the LPG with a 15 wt% DTBP was more than 55 suggesting the possibility of utilizing LPG as a DME(dimethyl ether). Exhaust emissions measurements showed that hydrocarbon was decreased with the blended fuel at enhancing cetane number. Furthermore, the combustion stability of LPG with a cetane number improver was comparable to DME fuel. Considering the results of engine performance and exhaust emissions, LPG blended fuel of enhancing cetane number could be used as an alternative fuel for diesel.

PAN 슬러리의 유변학적 거동 및 PAN 슬러리 기포탑에서 슬러리 입자의 축방향 분산

최상원,나종복,서호준 麗水水産大學校産業技術硏究所 1992 産業基術硏究所 論文集 Vol.1 No.-

Rheological parameters of PAN(polyasrylonitrile)-slurry such as shear modulus, relaxation time, structural factor, etc. have been determined. Axial concentration distribution and axial dispersion coefficient of slurry particles have been investigated in a PAN-slurry bubble column(0.10 m-ID x 1.53 m-height). Effects of gas velocity(0.03-0.11 m/s), apparent slurry viscosity ?? and concentration of slurry particles ?? on the axial concentration distribution and dispersion coefficient of slurry particles have been determined. Sedimentation-dispersion model has been employed to analyze the axial concentration distribution of slurry particles. The axial distribution of slurry particles became uniform with increases in gas velocity, apparent slurry viscosity and slurry particle concentration. The axial dispersion coefficient of slurry particles increased with increasing gas velocity, but it decreased with an increase in apparnet viscosity of slurry. By considering the relation between rheological properties and axial dispersion of slurry particles, we found the following correlation equation; ? ?