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      • KCI등재

        근관치료용 전기모터의 회전 안정성 평가

        박세희,서현우,홍찬의 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.4

        수종의 근관치료용 전기모터들의 반복사용과 시간에 따른 회전속도의 변화를 비교하여 근관치료용 전기모터의 회전 안정성을 평가하고자 하였다. 시간에 따라 변화하는 실제회전속도 및 전압과 전류를 측정하고, Student t-test를 통한 실제회전속도와, 반복측정분석을 통한 상관관계를 비교분석 하였다. 동일 종류의 전기모터들 사이의 모든 측정 결과들은 차이를 보이지 않았다. 모든 전기모터에서 반복사용과 시간의 흐름에 따른 회전속도의 변화는 차이를 보이지 않았다. 이상의 결과로, 본 실험에 사용된 모든 전기모터는 일정한 회전속도를 유지해야 하는 회전 안정성의 조건에 충족됨을 알 수 있으며, 반복사용과 시간에 따른 신뢰성 있는 회전속도와 안정적인 전압 및 전류의 유지가 가능하리라 생각된다. The purpose of this study was to evaluate a rotational stability of endodontic electronic motors by comparing the changes of rotational speed, depending on the number of usages and with/without static load. Twelve new endodontic electronic motors were used in this study. Non contact type digital tachometer was used for measuring the rotational speed of handpiece. True RMS Multimeter was used for measuring the voltages and the electric currents. All measurements were recorded every 10 seconds during 10 minutes and repeated 9 times. Five repetition was done per each electronic motor. To statistical analysis, student t-test, repeated measures and Scheffe's post-hoc tests were performed. In the same motor group, there was no significant difference in all measurements. In all groups, there was no significant difference in the amount of rotational speed changes depending on the number of usages and with/without static load. In the limitation of this study, the results showed that all kinds of endodontic electronic motors in this study had an established rotational stability. Therefore they could be safely used in root canal treatment with areliable maintenance of rotational speed, regardless of the number of usages and with/without load.

      • 간외담관 폐쇄에서의 초음파소견 : 담관벽 경계소실의 중요성 Significance of Decreased Echotexture of Bile Duct Wall-Interface

        신현준,손은주,이창희,최영칠,전혜정,박정희,이태의 건국대학교 의과학연구소 2002 건국의과학학술지 Vol.12 No.-

        Ultrasound is very useful in evaluation of obstructive jaundice. We retrospectively evaluated the useful findings of ultrasonography in differentiating benign extrahepatic duct obstruction from malignant diseases. Among the 36 patients, 25 patients were benign extrahepatic obstruction and 11 patients were malignant obstruction. The shapes of extrahepatic dilatation were classified into fustiform, meniscus, and abrupt cut off by bowel gas. The diameter, length, and bile duct wall-interface were compared between benign and malignant groups and serum bilirubin and alkaline phosphatase were also compared between two groups retrospectively. The results were as follows. The most common form of extrahepatic dilatation was meniscus(10 of 26 patients, 38%) in benign obstruction, and fusiform(8 of 11 patients, 73%) in malignant obstruction. No significant difference was noted in diameter, length, serum bilirubin, and alkaline phosphatase between benign and malignant groups. Only one case showed decreased bile duct wall-interface in benign obstruction, but loss or decrease of bile duct wall-interface were 8 patients in malignant obstruction. The combined findings of fusiform dilatation and loss of bile duct wall-interface in ultrasonography will be helpful in differential diagnosis of malignant extrahepatic bile obstruction from benign conditions.

      • KCI등재

        원저 : 자궁내 태아사망의 임상적 고찰

        이현의 ( Hyun Ui Lee ),박현수 ( Hyun Soo Park ),임형수 ( Hyung Su Lim ),김건우 ( Kun Woo Kim ),박찬우 ( Chan Wook Park ),박중신 ( Joong Shin Park ),전종관 ( Jong Kwan Jun ),윤보현 ( Bo Hyun Yoon ),신희철 ( Hee Chul Syn ) 대한주산의학회 2006 大韓周産醫學會雜誌 Vol.17 No.4

        목적 : 본 연구는 자궁내 태아사망의 임상적 특성 및 원인을 분석하여 자궁내 태아사망예방 및 관리에 도움이 되고자 함이다. 방법:1996년 3월 부터 2006년 3월까지 10년간 본원 산부인과에서 관찰된 184예의 자궁내 태아사망을 대상으로, 의무기록을 기초로 하여 임상적 고찰을 시행하였다. 이 중 의무기록 소실로 의무기록을 확인할 수 없었던 14예는 원인, 원인 진단과정에 대한 분석에서는 제외하였다. 결과 : 자궁내 태아사망의 전체 발생빈도는 1.31%였으며 연구 기간 동안의 연도별 발생률에서 차이는 없었다. 대상 산모의 연령은 18세에서 44세까지의 분포를 보였고 30~34세 군을 기준으로 하였을 때 24세 이하 군과 25~29세 군에서 각각 2.455, 1.590의 위험도를 보였으며 통계적으로 의미를 가졌고, 35~39세 군과 40세 이상 군에서는 위험도가 증가하는 경향을 보였으나 통계적 의미를 가지지 않았다. 임신 주수별 자궁내 태아사망의 발생빈도는 각각 29주 미만 38.58%, 29~36주 30.43%, 36주 이상 30.97%의 비율을 보였다. 분만방법은 질식분만이 총 147예(86.5%)였고, 자궁절개술은 14예(8.2%)로 모두 임신 30주 이상의 경우에 시행하였다. 자궁내 태아사망의 원인은 원인불명이 170예 중 63예(37.1%), 태아 측 인자가 50예(29.4%), 태반 및 제대인자가 31예(18.2%), 모체 측 인자가 26예(15.3%)였다. 총 170예 중 128예(75.3%)에서 부검을 시행하였고 148예(87.1%)에서 태반 조직 검사를 시행하였으며 진단과정 중 가장 의미가 있었던 검사는 부검과 태반 조직검사였다. 결론 : 산전관리기술의 발달에도 불구하고 자궁내 태아사망의 빈도는 비교적 일정하게 나타나고 있으며, 원인을 알 수 없는 경우가 가장 많았다. 자궁내 태아사망이 발견된 경우 즉각적인 분만이 이루어져야 하며, 적절한 검사로 태아 사망의 원인을 평가하는 것이 향 후 임신에 도움을 줄 수 있을 것이다. Objective : To investigate the clinical characteristics and etiologic factors of pregnancies with fetal death in utero (FDIU). Methods : Retrospective review of medical records of 184 pregnancies with FDIU between March 1996 and March 2006 was conducted and descriptive analysis was done. Medical records were unavailable in 14 cases which were excluded in the analysis of etiology and diagnostic evaluation. Results : The overall incidence was 1.31%. There was no significant difference in the yearly incidence during the study period. Age distribution of FDIU was between 18 and 44 and the incidence was highest in 25~29 year-old age group. The risk analysis showed statistically significant risk in the age group under 25 (OR, 2.455) and 25~29 (OR, 1.590) compared to 30~34 year-old age group. The risk of age group beyond 35 has a tendency to increase but was not statistically significant. FDIU was the most prevalent (38.58%) among pregnancies less than 29 weeks of gestation. Most of cases were delivered vaginally (86.5%). Etiologic factors included unexplained causes (37.1%), fetal factors (29.4%), placental and cord factors (18.2%) and maternal factors (15.3%). Autopsy was done in 128 cases (75.3%) and placental pathology was examined in 148 cases (87.1%). Among the workups done, autopsy and placental pathology were the most informative. Conclusion : Despite the advance of prenatal care, the incidence of FDIU was steady throughout the study period. The etiology of the largest proportion was unexplained. Once FDIU is diagnosed, prompt delivery should be done and appropriate diagnostic tests should be offered to aid in next pregnancy.

      • SCISCIESCOPUS

        Piperine, a Componentof Black Pepper, Inhibits Adipogenesisby Antagonizing PPARγ Activity in 3T3-L1 Cells

        Park, Ui-Hyun,Jeong, Hong-Suk,Jo, Eun-Young,Park, Taesun,Yoon, SeungKew,Kim, Eun-Joo,Jeong, Ji-Cheon,Um, Soo-Jong American Chemical Society 2012 Journal of agricultural and food chemistry Vol.60 No.15

        <P>This study investigated the antiadipogenic activity of black pepper extract and its constituent piperine in 3T3-L1 preadipocytes as well as the underlying molecular mechanisms. Both black pepper extract and piperine, without affecting cytotoxicity, strongly inhibited the adipocyte differentiation of 3T3-L1 cells. The mRNA expression of the master adipogenic transcription factors, PPAR gamma, SREBP-1c, and C/EBP beta, was markedly decreased. Intriguingly, mRNA levels of PPAR gamma target genes were also down-regulated. Moreover, a luciferase reporter assay indicated that pipierine significantly represses the rosiglitazone-induced PPAR gamma transcriptional activity. Finally, GST-pull down assays demonstrated that piperine disrupts the rosiglitazone-dependent interaction between PPAR gamma and coactivator GBP. Genome-wide analysis using microarray further supports the role of piperine in regulating genes associated with lipid metabolism. Overall, these results suggest that piperine, a major component of black pepper, attenuates fat cell differentiation by down-regulating PPAR gamma activity as well as suppressing PPAR gamma expression, thus leading to potential treatment for obesity-related diseases.</P>

      • KCI등재

        Joinpoint Regression About Injury Mortality and Hospitalization in Korea

        Hyun Jin Park,Ui Jeong Kim,Won kyung Lee,Bohyun Park,Yoonhee Shin,Seonhwa Lee,Eunjeong Choi,Nam-eun Kim,박주옥,Hye-Sook Park 대한의학회 2022 Journal of Korean medical science Vol.37 No.3

        Background: Injury is a social problem that causes health and property losses, and it is important to identify the size and trend of injury for efficient prevention and management. Therefore, this study analyzed the trends in injury mortality and hospitalization rates from 2005 to 2019 in Korea. Methods: Using mortality data by Statistics Korea and Korea National Hospital Discharge In-depth injury survey by the Korea Disease Control and Prevention Agency (KDCA), age standardized rates were calculated for death and hospitalization to analyze trends and annual changes with the joinpoint regression model. In addition, annual changes in the hospitalization rate of the transport accident and fall injuries by age group were analyzed, which are the major causes of injuries. Results: From 2005 to 2019, the injury mortality rate has been on the decline, but the injury hospitalization rate has been on the rise. The annual rate of change varied depending on the injury mechanism, but the mortality rate tended to decrease or remain similar level, while the rate of hospitalization has steadily increased. In addition, by age group, injury mortality and hospitalization rates were high in the elderly. In particular, the hospitalization rate of the elderly was higher when comparing the hospitalization rate of the children in transport accidents and falls. Pedestrian transport accidents tended to decrease under the age of 15, but remained similar for those aged 65 and older, and bicycle accidents tended to increase in both groups. In addition, hospitalization rates were higher in the fall, with both groups showing a statistically significant increase in hospitalization rates caused by falls. Conclusion: This study analyzed the trend of injury mortality and hospitalization and found that transport accidents and falls may vary depending on the means or age of the accident. Since injury is a big social problem that is a burden of disease, safety education and legal sanctions for injury prevention should be further improved in the future, especially by prioritizing vulnerable groups by age and detailed mechanisms of injury.

      • KCI등재

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