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그람양성구균에 대한 Teicoplanin과 Vancomycin의 시험관내 항균력
최태열,김경숙,전용관,서일혜,김정욱,이웅수,안정열,김홍석,정재용,최효선,김덕언,유진우 대한감염학회 1994 감염 Vol.26 No.1
An increasing frequency of methicillin resistant S. aureus(MRSA), methicillin resistant coagulase negative staphylococci(MRCNS) and Enterococcal infection have been observed in recent years. Teicoplanin is a new glycopeptide antibiotic obstained from the Actinoplanes teicomycetius. The molecular structure and spectrum of antimicrobial activity of teicoplanin is simillar to those of vancomycin, and has been reported to have an excellent in vitro and in vivo effect against various gram-positive infections. Therefore, we evaluated the in vitor susceptibility of gram positive cocci, such as, S. aureus, coagulase negative Staphylococci(CNS), and Enterococci to teicoplanin and vancomycin. The total 253 strains consisted of MSSA(40), MRSA(53), MSCNS(47), MRCNS(48), and Enterococci(65). They were assayed by disc diffusion and agar dilution. During the study, 57% of S. aureus and 49% of CNS showed resistance to methicillin. The inhibitory diameter of teicoplanin was 15-20mm in MSSA, 12-19mm in MRSA, 13-24mm in MSCNS, 11-23mm in MRCNS, and 15-22mm in Enterococci respectively, and showed sensitivity in all but 8 strains(3.2%). The range of the minimum inhibitory concentration (MIC) of teicoplanin to MSSA, MRSA, MSCNS, MRCNS and Enterococci were 9.12-2.0㎍/ml, 0.25-2.0㎍/ml, & 0.25-32㎍/ml, 0.12-1.0㎍/ml respectively. One case of S. haemolyticus was resistant to teicoplanin (32㎍/ml) by the agar dilution method. Eight minor (3.2%) and one major(0.4%) error was observed when the MIC and disk diffusion data were correlated with teicoplanin. As for vancomycin the inhibitory diameter was 17-21mm in MSSA, 15-21mm in MRSA, 18-26mm in MSCNS, 18-25mm in MRCNS, and 16-22mm in Enterococci respectively. The range of the MIC of vancomycin to MSSA, MRSA, MSCNS, MRCNS, and Enterococci were 0.25-1.0㎍/ml, 0.25-4.0㎍/ml, 0.5-2.0㎍/ml and 0.5-2.0㎍/ml respectively. One minor error (0.4%) was seen with the vancomycin disk. The MIC90 of MSSA and MRSA exhibited the same results in teicoplanin (1.0㎍/ml, 1.0㎍/ml), and vancomycin(2.0㎍/ml, 2.0㎍/ml). MSCNS and MRCNS exhibited greater MIC90 with teicoplanin(4.0㎍/ml, 8.0㎍/ml) than vancomycin(2.0㎍/ml, 2.0㎍/ml). Incontrase Enterococci were more susceptible to teicoplanin(0.5㎍/ml) than to vancomucin (2.0㎍/ml). Results from this analysis indicated that both teicoplanin and vancomycin were very excellent for gram positive infections, especially those resistant to methicillin.
도계처리과정에 사용되는 물에서 분리한 세균군과 각 세균종에 대한 살균제의 효능에 대하여
김성일,오경록,안동수,안태근,고경원,이민웅 동국대학교 대학원 1987 大學院硏究論集-東國大學校 大學院 Vol.17 No.-
The highest number of bacterial cell was observed in chicken washed water compared with the natural and chilled water. Fifteen bacterial strains were islated from the chicken processing water. When they were identified by the Bergey's Mannual of determinative bacteriology, they were all identified as the family Enterobacteriaceae; one genus of Citrobacter, three genera of Enterobacter, and four genera of Klebsiella except one isolate unknown. The concentration of Na₂HCIO₄to inhibit all the bacterial strains 30ppm, on the other hand the concentration of CIO₂to retard bacterial growth was 70ppm. The effective concentration of CIO₂was various according to bacterial species.
Treatment of panfacial trauma patient via submental intubation: a case report
( Tae-woong Ahn ),( Kil-hwa Yoo ),( Min-seok Oh ),( Chul-min Park ),( Seong-hoe Yoon ),( Sun-woong Yoon ),( Ka-young Seol ),( Dong-keun Lee ),( Young-ju Park ),( Dong-soo Shin ) 조선대학교 구강생물학연구소 2017 Oral Biology Research (Oral Biol Res) Vol.41 No.4
Airway management in complex craniomaxillofacial trauma surgery is an important factor, and the choice of the intubation technique is often difficult and challenging. The choice of the intubation technique requires good assessment by the multidisciplinary team that includes maxillofacial surgeons and neurosurgeons as well as good communication between them. Submental intubation is a technique that is maintained extraorally after the conventional orotracheal intubation and the tube is extruded through the incision site in the submental region. It is a useful and safe airway management technique for craniomaxillofacial trauma surgery. It makes it possible to perform reduction of the nasal-orbital-ethmoidal complex fracture, and LeFort I, II, III fractures simultaneously. The aim of this study is to report a case of a craniomaxillofacial trauma patient who had an accompanying periorbital space abscess and treatment was performed by open reduction and internal fixation via submental intubation with a review of literature. After considering the method, complications and indications, we suggest this technique for safe and useful airway management of craniomaxillofacial trauma surgery.
Ahn Sun Tae,Shim Ji Sung,Bae Woong Jin,Kim Sae Woong,Kim Je Jong,Moon Du Geon 대한남성과학회 2022 The World Journal of Men's Health Vol.40 No.2
Purpose:Purpose: We aimed to evaluate the efficacy and safety of penile girth enhancement (PGE) using hyaluronic acid (HA) filler with different physical properties from previous studies. Additionally, we evaluated the clinical impact on ejaculation after PGE. Materials and Methods:Materials and Methods: This was a prospective, patient/evaluator-blinded, randomized, active-controlled, multicenter trial. Patients recruited between December 2017 and March 2018 were randomly assigned to the HA filler or control group (poly-lactic acid [PLA] filler). Penile girth, satisfaction level, Premature Ejaculation Profile (PEP), and self-estimated intravaginal ejaculation latency time (IELT) were assessed at baseline and at 24 weeks post-injection. Results:Results: Sixty-four subjects (32 in each group) completed the trial. The mean increase in girth was 22.74±12.60 mm and 20.23±8.73 mm in the HA and control groups, respectively. Satisfaction level regarding penile appearance and sexual life significantly increased in both groups. There was no statistically significant difference between the groups in terms of in-crease in penile girth or change in satisfaction level. Both groups showed significant improvements in PEP index scores. Self-estimated IELT also significantly increased in the HA group (from 5.36±3.51 to 7.86±4.73 minutes, p=0.0001) and control group (from 5.23±3.55 to 6.43±4.22 minutes, p=0.021). No serious adverse events (AEs) were reported. CCoonncclluussiioonnss:: PGE with HA and PLA fillers resulted in significant enhancement of girth without serious AEs with no significant differences. Furthermore, PGE using filler improved clinical symptoms related to ejaculation.