공복 시 Caffeine 투여 후 일회성 운동이 흰쥐의 인슐린 및 골격근의 GLUT-4 발현에 미치는 영향

정일규,오명진,김영표,김종오,윤재석,서태범,윤진환 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.5

This study was done to investigate the effects of caffeine ingestion on the expression of GLUT-4 in rats' skeletal muscle(soleus m) and blood insulin level after 12 hr fasting condition and one hour treadmill running. Total 19 rats(Sprague-Dawley) who were 7week Did were used for experimental subjects and raised for 1week in the room controled the air temperature and relative humudity(22℃ and 50%). They were divided three groups ; 12hr fasting group(F group, n=5), fasting+exercise group(FE, n= 7) and fasting+caffeine+exercise group(FCE group, n=7). FG and FCE group performed treadmill running for one hour and the treadmill speed was 18m/min that was supposed to be moderate exercise to rats. Each Dr rats in FCE group was forced to he given the caffeine solution(5mg/kg, Sigma Chemical co.) through stainless steel tube directly to their stomachs one hour before treadmill exercise. Immediately after treadmill running, we anesthetized them with the mixed solution(Ketamin 80g/kg and Rompun 5ml/kg) to draw 3ml blood from heart four insulin analysis and then obtained the rats' soleus muscle for GLUT-4 expression. We found that FCE group showed significantly higher GLUT - expression then the other groups and FE group showed the lowest GLUT-4 expression. This rusults suggest that the endurance type of exercise in fasting condition inhibit the GLUT-4 expression in working muscle and the caffeine helped to facilitate the GLUT-4 expression during endurance type of exercise. The future studies needed to confirm the action of caffeine to increase the GLUT- 4 and the mechanism.

CITIS 지원 기술정보관리 시스템의 설계

정석찬,한태창,서범수,조장혁,주경준 한국경영과학회 1998 한국경영과학회 학술대회논문집 Vol.- No.1

CITIS(Contractor Integrated Technical Information Service) is a contractor's developed service to provide electronic access and/or delivery of contractually required information. CITIS satisfies one of the major CALS objectives to furnish a single-entry point for authorized access to contractor-generated Contract Data Requirement List(CDRL) data. A critical requirement for the practical implementation of the CITIS concept is the ability to access multiple existing heterogeneous databases in a fashion transparent to the CITIS user. In this paper, we will propose a prototype system model for CITIS, and discuss the system architecture of proposed CITIS system as a global information management system for distributed and heterogeneous local information systems. Furthermore, we will discuss about the required server module and using-scenario of proposed CITIS system.

Redundant Multi-Valued Logic을 이용한 4.5 Gb/s CMOS Demultiplexer 구현

김태상,김정범 강원대학교 정보통신연구소 2006 정보통신논문지 Vol.10 No.-

This paper describes a high speed interface using redundant multi-valued logic for high speed communication ICs. This circuit is composed of encoding circuit that serial binary data are received and converted into parallel redundant multi-valued data to parallel binary data. Because of the multi-valued data conversion, this circuit makes it possible to achieve higher operating speeds than that of a conventional binary logic. Using this logic, a 1:4 DEMUX (Demultiplexer, serial-parallel converter) was designed using a 0.35um standard CMOS technology. Proposed DEMUX is achieved an operating speed of 4.5Gb/s with a supply voltage of 3.3V and with power consumption of 53mW. The operating speed of this circuit is limited by the maximum frequency which the 0.35um process has. Therefore, this circuit is to achieve COMS communication ICs with an operating speed greater than 10Gb/s in submicron process of high operating frequency.

아파트단지내 조경시설물 평가에 관한 연구 : 수원 매탄5단지를 사례로 A Case Study of Maetan Apartment Complex in Suwon, Korea

김학범,김정태,임형준 안성산업대학교 2002 論文集 Vol.34 No.-

This study aims to provide useful data for designing the outdoor space or planning landscape architecture facilities in apartment housing complex. Primary data were collected by questionnaire survey in Maetan Apartment Complex in Suwon. The questionnaires contain three sets of variables : outdoor environment, landscape architecture facilities, and the respondents' demographic variables. The results are as follows. 1) The apartment residents are using bench or pergola most frequently among the landscape architecture related facilities. 2) The residents are dissatisfied with shortage of parking lots, therefore, more parking area is needed in the apartment complex. 3) The residents expressed considerable concern for trees, however, they pointed out to change some species of trees and need some professional management for them. 4) The variables related landscape architecture facilities were reduced to 6 factors; 'trees', 'bench/pergola', 'excercise/playground', 'pavement', 'lighting facility', 'parking lots'. And 'trees' is perceived the most important factor by the residents. 5) Finally, 'landscape architecture facilities', is most important factor among variables consist of apartment exterior environment.

정신과 입원환자에서의 혈청 콜레스테롤 농도와 공격행동

전태연,도규영,정종현,권용실,김석범 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.5

목 적 : 혈청 콜레스테롤 농도와 자살 등의 공격행동간의 연관성에 관한 여러 연구가 있었으나 일치된 결과를 보이고 있지 못하다. 이에 저자들은 다양한 진단의 정신과 입원 환자들 중 공격행동을 보인 환자의 콜레스테롤 농도를 정상 한국 성인에서의 혈청 총 콜레스테롤의 성별, 연령별 평균 및 표준편차와 percentile분포에 맞추어 공격행동 및 자살시도와 혈청 콜레스테롤 농도간의 연관성을 알아보기 위하여 본 연구를 시행하였다. 방 법 : 본 연구는 1994년 1월 1일부터 1995년 6월 31일까지 18개월간 카톨릭대학교 의정부성모병원 정신과 병동에 입원하였던 환자 중 콜레스테롤 농도를 얻을 수 있었던 127명을 대상으로 하였다. 대상 환자는 공격행동의 유무에 따라 공격군과 비공격군으로 분류하여 공격군 35명과 비공격군 92명의 자료를 얻었으며, 공격군은 Overt Aggression Scale을 사용하여 평가하였다. 측정된 각 환자의 콜레스테롤 농도는 정상 한국 성인에서의 혈청 총 콜레스테롤의 성별, 연령별 평균 및 표준편차와 percentile분포에 맞추어 4개의 군으로 나눈 후 공격행동 발생비율, 자살시도간의 차이를 알아보았다. 또한 공격행동을 보인 군에서도 각 콜레스테롤군 간의 총 공격 점수를 비교하였다. 결 과 : 1) 각 콜레스테롤군 간의 공격행동 발생비율에는 유의한 차이가 없었다. 2) 공격군에서 각 콜레스테롤군 간의 총 공격 점수는 유의한 차이를 보이지 않았다. 3) 각 콜레스테롤군 간의 자살시도 빈도는 유의한 차이가 없었다. 결 론 : 정신과 입원 환자의 혈청 콜레스테롤 농도를 정상 한국 성인에서의 혈청 총 콜레스테롤의 성별, 연령별 평균 및 표준편차와 percentile분포에 맞추었을 때 혈청 콜레스테롤 농도와 공격행동 및 자살시도에 유의한 연관이 없었다. Objectives : An association between serum cholesterol concentration and violent behavior has been suggested, but has not been consistently demonstrated. This study was conducted in order to evaluate the relation between serum cholesterol concentration and violent behavior in psychiatric inpatients who had been admitted at Uijongbu St. Mary's Hospital, the Catholic University of Korea from January 1994 to June 1995. Methods : We divided the 127 subjects into violent(35 subjects) and non-violent group(95 subjects). According to the percentile distribution of serum total cholesterol in healthy Korean adults, the subjects were classified into four subgroups : Group 1, subjects Whose cholesterol concentrations were below 26% of percentile distribution, Group 2, from 26% to 50%, Group 3, 51% to 75% and Group 4, above 75%. In the four cholesterol subgroups, the authors examined the incidence of violent behaviors and suicidal attempts. Within the violent group, total aggression score of four cholesterol subgroups was compared. Results : 1) Among the four cholesterol subgroups, there were no significant differences in the violent behavior. 2) Within the violent groups, total violent score of the four cholesterol subgroups showed no significant difference. 3) Among the four cholesterol subgroups, there were no significant differences in suicidal attempt. Conclusion : When the serum cholesterol concentrations of psychiatric inpatient applied to the percentile distribution of serum total cholesterol in healthy Korean adult, no association was found between serum cholesterol concentration and violent behavior and suicide attempt.

조경분야의 이용후평가 적용모델과 그 가능성에 관한 연구

김학범,장동수,김정태 안성산업대학교 1997 論文集 Vol.29 No.2

The purpose of this study is to present a process model and outline of steps of POE that can be applied to outdoor open space, to review some POEs of urban parks(Yangjae Forest Park, Namsankol Park, and Paris Park) in Seoul Korea, and to offer some suggestions to landscape architects. This paper is organized as follows; The next section reviews the history of papers written about urban park and green space, and finds put the trend and context of some POE papers. Section 3 explains the method and technics of POE survey and purposes a POE process model. Section 4 studies restrains and possibilities in applying POE into landscape architecture by reviewing some POEs of urban parks in Seoul. And last section summarizes the findings of this study and offers some suggestions applying POE into landscape architecture.

뇌실내출혈로 인한 급성 수두증에서 관찰된 해리증후군

김광기,이경민,이정주,오종배,안태범,정상욱,남현우,박성호 대한신경과학회 1999 대한신경과학회지 Vol.17 No.5

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

공기재생용 고온건식탈황제의 가압유동층 반응기에서의 사이클 성능실험

조성호,이봉희,이중범,류청걸,진경태,이창근 한국화학공학회 2002 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.40 No.2

고온고압 기포유동층 반응기에서 분무건조기로 성형제조한 아연계 탈황제(ZAC C)에 대하여 총 6회 황화-재생 반복실험을 500℃, 5atm 조건에서 수행하였다. 1% H_2S를 포함한 석탄모사가스를 반응기에 주입하여 황화반응을 시킨 결과 배출가스 중 H_2S 농도는 10ppmv 이하로 유지되었다. ZAC C의 황흡수력은 6회 황화반응 동안 각각 11.1, 10.9, 11.1, 11.1, 10.9, 10.5g S/100g sorbent으로 유지되어 초기 황흡수력을 유지하였다. 공기를 이용한 500℃ 재생반응에서 배출되는 SO_2의 최대농도는 양론적으로 이론값과 일치하였다. 재생반응에서 탈황제 층의 온도는 발열반응에 의해 500℃에서 최대 750℃까지 상승하였다. 연속 70시간 동안 유동층 반응기내에서 실시된 ZAC C 탈황제의 비산되어 유출된 양은 1.07%이고, 실험 후 탈황제의 크기와 조직특성의 변화도 적었다. 고온고압반응기 multi-cyclone 실험결과 ZAC C 탈황제는 이론 황흡수력의 50% 이상을 유지하였고, 공기를 사용한 500℃의 재생반응이 원활하고 완전히 이루어졌고, 황산염생성과 같은 부반응이 없었다. Two desulfurization-regeneration experiments for a spray-dried zinc-based sorbent(ZAC C) were performed at 500℃ and 5 atm in a fluidized-bed reactor(ID 0.097㎜) facility. The H_S concentration after each desulfurization run was maintained below 10 ppmv from a simulated coal gas of 1% H_2S. The estimated sulfur absorption capacities of ZAC C sorbent were 11.1, 10.9, 11.1, 11.1, 10.9, 10.5 g S/100g sorbent, and the sorption capacity of sorbent was maintained in spite of six times sorption experiments. The maximum SO_2 concentration in regeneration effluent gas agreed with a stoichiometric value of 500℃(ca. 14vol%). In regeneration run, the peak temperature of sorbent bed in the reactor reached up to 750 due to the vigorous exothermicity of regeneration reaction with neat air. While entrainment rate for 70h continuous run in fluidized-bed reactor is 1.07%, the size and the textural properties of ZAC C sorbent also show a little change. Multi-cycle tests in fluidized-bed show that ZAC C sorbent maintains over 50% of its theoretical sorption capacity during 70h run and regeneration reaction undergoes smoothly and completely without side reactions such as sulfate formation.

토끼에서 근육주사시 입자 크기에 따른 amoxicillin의 비교 약물동태학

박승춘,윤효인,오태광,장범수,배순이,조준형,정상희,이내경,김민규 충남대학교 수의과대학 동물의과학연구소 1998 動物醫科學硏究誌 Vol.6 No.-

To investigate the pharmacokinetic difference between the two amoxicillin (AMX) particles in rabbits after intramuscular injection (i.m.), both of AMX-S (particle size: 10 ㎍) and AMX-L (particle size: 100 ㎍) were injected into New Zealand White rabbits (1.2±0.3 ㎏) at a dose rate of 10 ㎎/㎏ of body weight. In this study, serum AMX concentrations were detected by microbiological assay with E. coli BE 1186 which shows high antibiotic sensitivity. After i.m. administration, AMX-S and AMX-L were best fitted as 1-compartment model with the absorption and elimination phase. The biological half-life (T_1/2, _k10) of AMX-S is 4.06±1.09 h and that of AMX-L 4.76±0.69 h. The serum maximal concentration time (T_max) of AMX-S and AMX-L were 0.88±0.17 h and 0.77±0.11 h, respectively. Maximal AMX concentration (C_max) (AMX-S: 5.71±0.62 ㎍/㎖, AMX-L: 5.04±0.25 ㎍/㎖) in serum showed a significant difference (p<0.05). In terms of bioequivalance, however, there was no difference between the two AMX's after i.m. injection in the basis of C_max and AUC.