미국의 동아시아 정책변화와 한반도에 관한 연구 : In connection with the Role of 「Jeju Peace Island」under the Changing Environment 환경변화에 따른 「평화의 섬」제주의 역할과 관련하여

고성준 제주대학교 동아시아연구소 2000 東아시아硏究論叢 Vol.11 No.-

인산염 처리에 따른 콩과 및 벼과 식물의 유기산 분비 및 인흡수량 차이

고미라,송성준,강영길 제주대학교 방사능이용연구소 2005 방사선응용과학연구소논문집 Vol.19 No.-

쪽파[Allium ascalonicum L.] 재배기간 중 Diazinon, Iprodione 및 Chlorfenapyr의 잔류랑 변화

고광용,나은식,김성헌,김상준,장영희,이규승 충남대학교 농업과학연구소 2005 농업과학연구 Vol.32 No.2

In order to know the residual pattern of pesticides and predict to the degradation period until below MRL, we experimented diazinon, iprodinon and chlorfenapyr for shallot. They were the most detected pesticide in shallot by NAQS (National Agricultural product Quality management Service) survey. In this experiment, we sprayed those pesticides 15days before harvest and analyzed 0, 1, 2, 3, 5, 7, 10, 14 day sample to establish logical equation and to calculate DT_(50). During the cultivating period, the residue amount of diazinon was changed from 1.02 mg/kg (0 day) to 0.01 mg/kg (14 day), DT_(50) was 2.19 days, and iprodione was changed from 1.45 mg/kg (0 day) to 0.14 mg/kg (14 day), DT_(50) was 4.15 days, and chlorfenapyr was changed from 1.5 mg/kg (0 day) to 0.01 mg/kg (14 day), DT_(50) was 1.97 days. The DT_(50) of double amount in those pesticides, diazinon was 2.24 days, iprodione was 4.82 days, and chlorfenapyr was 2.24 days, respectively.

유기인제 중독 후 발생한 중간형 마비 증후군

고재욱,박준석,이경룡,정성필,이한식 대한응급의학회 2000 대한응급의학회지 Vol.11 No.4

Background: Intermediate myasthenia syndrome(IMS) is thought to have clinical importance because it may cause sudden respiratory failure during the recovery phase of a cholinergic crisis of organophosphate poisoning. We designed this study to identify the prevalence, the inducing agent, clinical predictor, and the proposed treatment of IMS. Methods: Patients who had admitted with the diagnosis of acute organophosphate poisoning from 1992 to 1998 at two teaching hospitals were enrolled in this study. We selected the cases of IMS based on a review of medical records using modified He' s criteria. Results: Twelve(12) out of 110 patients with acute organophosphate poisoning were diagnosed for a prevalence at 10.9%. The drug inducing IMS were identified as dichlorvos, fenthion, EPN, methidathion, and phosphamidon. The occurrence of IMS was not related to either the initial treatment with atropine and pralidoxime, or the level of serum cholinesterase. Complications were pneumonia, sepsis, pancreatitis, and pseudomembranous colitis, etc. Eleven(11) patients were discharged without sequelae, and one patient was discharged as a hopeless case. Conclusion: This study suggests that IMS is not rare, so close observation is required to detect IMS in organophosphate-poisoning patients. Also, more studies are required to find predictors and treatments.

유산소성 운동이 고지혈증 여성 고령자들의 APO 지단백 대사에 미치는 영향

고기준,김성헌 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.3

The purpose of this study was to determine the effects of continuous and intermittent treadmill exercise training on the change of apoprotein metabolism in hyperlipidemia female olders. Subjects was selected among the hyperlipidemia female olders who were enlisted in the old medical center in P metropolitan city. These subjects were female olders with hyperlipidemia syndrome who agreed with intention and experimental content of this study. Subjects were composed of 6 continuous group(average age of 71.2±2.3yrs) and 7 intermittent group(average age of 69.6±3.0yrs), total 13 members. Continuous and intermittent treadmill exercise training program were performed with intensity of 65~75% HRmax and RPE 13~15, for 30 min./day, 3 times/week during 10 weeks. The conclusion obtained from this study were as follows; 1. Apo AI after exercise was increased by 20.7% in continuous group, 15.3% in intermittent group but with no statistical signification. 2. Apo AⅡ after exercise was increased by 10.4% in continuous group, and decreased by 2.2% in intermittent group but with no statistical signification. 3. Apo B after exercise was increased by 17.9% in continuous group, 4.0% in intermittent group but with no statistical signification. 4. Apo CⅡ after exercise was increased significantly by 54.1%(P<0.01) in continuous group, and increased by 19.4% in intermittent group but with no statistical signification. 5. Apo CHI after exercise was increased significantly by 40.6%(P<0.05) in continuous group, and 44.6%(P<0.05) in intermittent group. 6. The ratio of HDL-C/Apo AI after exercise has been increased significantly by 111.0%(P<0.001) in continuous group, and 81.3%(P<0.001) in intermittent group. 7. The ratio of LDL-C/Apo B after exercise has been increased significantly by 94.2%(P<0.001) in continuous group, and 81.6%(P<0.01) in intermittent group.

마라도 주변해역의 해저지형과 해황 특성

김준택,노홍길,김상현,고준철,문승업 제주대학교 해양연구소 2001 해양자원연구소연구보고 Vol.25 No.-

Raphanus sativus Var. Chungpihongsim의 hairy root 배양에 의한 anthocyanin 생성

황성진,백윤웅,고경민,안준철,황백 全南大學校 農漁村開發硏究所 1991 農業科學技術硏究 Vol.26 No.-

청피홍심무우를 재료로 A. rhizogenes A₄균주를 접종하여 hairy root를 유도하였으며 유도된 hairy root는 paper electrophoresis를 통하여 mannopine과 agropine이 검출되어 형질전환 되었음을 확인하였다. Hairy root는 MS의 기본염을 1/2로 희석시킨 1/2 MS, sucrose 3%, pH 5.2로 조성된 배지에서 최적인 성장을 보였다. 유도된 hairy root는 각 strain사이에 색소능에 다소간의 차이를 보였으며 2, 4-D kinetin의 적절한 조합의 처리구에서는 탈분화와 더불어 색소가 형성되었고, 그 중 2, 4-D와 kinetin을 각각 1 ppm, 5 ppm 처리하였을 때 최대 색소능을 보였다. hairy root의 탈분화시 형성되는 색소는 원 식물 뿌리의 주 색소인 pelargonidin 계열의 색소로 추정되며 총 색소량은 49mg/100g(F.W.)로 잠정 계산되었다. Hairy root induced following inoculation of the root disc and plantlet fragment of R. sativus Var Chungpihongsim with A. rhizogenes A₄. The hairy root contained agropine and mannopine. Medium contained 1/2 MS salt, sucrose 3%, pH 5.2 was optimized to growth of hairy root. Depending on the hairy root line, the level of pigment in hairy root varied somewhat . When 2, 4-D and kinetin were added in hairy root, the synthesis of pigment induced with deorganization of hairy root. Especially, addition of 2, 4-D 1 ppm and kinetin 5 ppm showed the maximum synthesis of pigment. Compared with anthocyanin extract of mature root three pigments were assumed to acylated pelargonin. The content of anthocyanin in these sample was 49mg/100(F.W.).

A2024와 SM45C 마찰용접의 열전달 해석

이상윤,고준빈,명태식,김기길,강형모 大田産業大學校 2001 한밭대학교 논문집 Vol.18 No.-

The heat transfer mechanism initiating the friction welding is examined and a transient three dimensional heat conduction model for the welding of two dissimilar cylindrical metal bars is investigated. The cylindrical metal bars are made of materials made of A2024 and SM45C. Numerical simulations of heat flow are performed using the finite volume method. Respectively, Commercial FLUENT code is used in the heat flow simulation and maximum temperature and distribution of temperature are calculated. Temperature of friction welded joining face is compared with the temperature distribution measured by experiment and numerical simulation. The maximum temperature of friction welded joining face is lower than melting point of A2024-T6 aluminum alloy using insert metal. The temperature distribution of friction welded joining face with insert metal is more uniform than that of without insert metal

광주의 한 이차병원에서 조사한 결핵약제 내성과 관련인자

조준호,김강,최상철,이경록,정종필,고영춘 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.3

연구목적: 우리나라의 결핵약제에 대한 내성은 지속적으로 감소되고 있음에도 불구하고 여전히 적지 않은 환자를 보유하고 있는 상황에서 치료 실패의 중요한 요인이 되고 있다. 이에 결핵 내성률에 영향을 미칠 수 있는 인자들을 파악하고 이에 대한 예방 대책을 수립하는 것이 내성률 발생의 예방에 도움이 될 것으로 사료된다. 이에 저자들은 광주 소재의 한 2차 병원에서 결핵 약제 내성률 및 위험인자로 판단되는 요소들과의 상호관계를 조사하였다. 대상 및 방법: 2005년 3월 부터 2006년 2월 까지 광주 기독 병원 내과에서 치료받은 결핵 환자중 객담 결핵균 배양 검사상 양성으로 판명되어 약제 감수성 검사를 확인할 수 있었던 346명을 대상으로 의무기록, 면담 등을 통한 후향적 조사를 시행 하였다 결과: 346명중 한가지 이상의 약제에 내성을 보인 경우는 150명(43.4%)였고, 다제 내성 결핵은 72명(20.8%)였다. 조사 요인의 유무별로 약제 내성률을 조사하였을 때 흉부 사진의 침범 정도에 따른 약제 내성률 및 다제 내성률은 경증에서 36.3%와 6.2%, 중등도에서 36.1%와 22.6%, 중증에서 61.0%와 35.0%였다. 병변의 공동성 병변 유무에 따른 약제 내성률은 공동이 있는 군에서는 49.8%, 공동이 없는 군에서는 34.0%였다. 과거의 치료력 여부에 따른 약 제 내성률은 치료력이 없는 군에서는 19.7%였고, 치료력이 있는 군에서는 81.2%였다. 항 결핵제 복용의 규칙성 여부에 따른 약제 내성률은 규칙적 복용군은 31.7%, 불규칙적 복용군은 59.7%로 나타났다. 결론: 광주 소재의 한 2차 병원에서 조사한 약제 내성률 및 다제 내성률은 전국 평균치를 훨씬 상회하였다. 한편 과거 치료병력 및 약제의 불규칙 복용은 약제 내성률을 높이는 데에 기여하는 인자가 될 것으로 사료된다. 흉부방사선 사진 상의 폐 침범 정도, 공동성 병변의 존재도 약제 내성률 증가와 관련이 있는 것으로 보이나 보다 정확한 선후관계 분석을 위해서는 추가적인 전향적 연구가 필요하다. Background and objectives: Drug resistance is a major obstacle to the treatment of pulmonary tuberculosis (TB). This study was conducted to determine the prevalence of drug-resistant tuberculosis and its associated factors at a secondary hospital in Gwangju. Materials and Methods: A retrospective one-center analysis was conducted, with 346 pulmonarytuberculosis patients who underwent drug susceptibility tests for M. tuberculosis at Gwangju Christian Hospital from March 2005 to February 2006. Results: The following percentages of subjects were found to be resistant to at least one drug and to have multidrug-resistant tuberculosis (MDR-TB), respectively: 43.4% and 20.8% of all the subjects; according to the severity of the chest X-ray findings, 36.3% and 6.2% in the mild group, 36.1% and 22.6% in the moderate group, and 61.0% and 35.0% in the far- advanced group; according to the presence of a cavitary lesion, 49.8% in the cavitary-lesion group and 34.0% in the noncavitary-lesion group and according to the history of previous tuberculosis treatment, 81.2% in the group who have had treatment and 19.7% in the group who have never had treatment. The resistance rate according to the regularity of antituberculosis drug medication was 31.7% in the regular medication group and 59.7% in the irregular medication group. Conclusion: The drug resistance rate was increased by the history of previous tuberculosis treatment and the irregular medication. As to whether the severity of chest X-ray findings and the presence of cavitary lesions have a correlation with drug resistance, prospective studies are needed for more accurate results.

마라도 주변해역의 해저지형과 해황 특성

김준택,노홍길,김상현,고준철,문승업 제주대학교 해양과환경연구소 2001 해양과환경연구소 연구논문집 Vol.25 No.-

We studied the characteristics of bottom topography and oceanographic conditions around Marado and Jeju Island. The obtained results are summarized as follow ; 1. A bottom topography around Marado is shows irregular radiation shape with abyssal zone depth from 100m to 150m, in spite that the depth below 100m is shown in the north and the depth below 100∼120m is shown widely and flatly in south. In addition to the fronts of temperature and salinity formed between inshore water and oceanic water, small-size eddies and actively horizontal and vertical mixings are formed by strong tide and geographical features including irregular topography and an isolated island. 2. Adjacent seas of the Marade are greatly influenced by the Tsushima current. The Tsushima water branches in two directions of northeast and northwest in the sourth sea of Jeju Island. The northwest current shows high temperature and salinity than the northeast, so such inflowing plays a role inducing high temperature and salinity water.