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김선민,이태용,오장균,박암 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.1
The author studied the recognition of patient's right and the degree of one's satisfaction to help set the index of doctor-patient relationship. The data was collected from 423 patients who were admitted to the hospital in Taejeon for fifteen days from Aug. 10, 1991 to Aug. 25, 1991. The results were as the follows: 1. The recognition of the patient's right and the degree of satisfaction were 4.46±0.734, 3.20±0.884 of total 5.0 score in each mean level. 2. "I believe a patient has a right to be treated equal.", "I believe a patient has a right to be compensated in medical accident." and "A patient should be told his diagnosis, treatment, prognosis about the disease by the doctor." were high mean level among each question. Their mean levels were 4.73, 4.69, 4.66 in sequence. 3. The recognition of patient's right by the age was the highest in teenager. It was lowest in above fifty years old. It was lower as age increase. There were statistically significant difference(P<0.05). The recognition of patient's right by the level of education was highest in college level and lowest in primary school level, but the degree of satisfaction was highest in primary school level and lowest in high school. The higher the education level was, the higher the recognition of patient's right was, but the lower it was, the higher the degree of satisfaction was. There was statistically significant difference(P<0.01). The recognition of patient's right be family income was highest in high income level but the degree of satisfaction was lowest. There was statistically significant difference in the recognition of patient's right(P<0.01). 4. Correlation between the recognition of patient's right and the degree of its satisfaction: "To be advised if the hospital proposes to engage in human experimentation affecting his care to patient one has the right to refuse to participate in such research projects was positive correlation with the degree of its satisfaction(r=0.1153). There was statistically significant difference(P<0.01). There were no correlation in other questions. 5. Correlation among each questions for the recognition of patient's right was highest between "…to expect that all communications and records pertaining to his care should be treated as confidential" and "…the right to know what hospital rules and regulations apply to his conduct as a patient"(r=.6314). 6. Correlation among each questions for the degree of satisfaction was highest between "…to considerate and respectful care" and "…to expect that within its capacity a hospital must make reasonable response to the request of a patient for services"(r=.6314).
새로운 세파로스포린 유도체의 합성과 항균력에 관한 연구
박의석,김하정,최원식,황선암 순천향대학교 기초과학연구소 1996 순천향자연과학연구 논문집 Vol.2 No.1
New cephalosporin antibiotics, 7-[(3,4-dihydro-6-methoxycarbonyl-2,2-dimethyl-2H-1,4-thiazin-3-yl 1-oxide) -acetamido]-3-heterocyclothiomethyl-3-cephem-4-carboxylic acid derivatives (2a-2d) were synthesized. Anti-bacterial activities of these new cephalosporin derivatives and the relationship between their stucture and their activities were examined. Among them, 7-[3,4-dihydro-6-methoxycarbonyl-2,2-dimethyl-2H-1,4- thiazin-3-yl1-oxide)acetamido]-3-[(2-methyl-1,3,4-thiadiazol-5-yl)thiomethyl]-3-cephem-4-carboxylic acid exhibited the broad antibacterial activities against Gram(+) and Gram(-) bacteria.
Eethyl benezylidencyanoacetate 유도체에 대한 thiophenol 첨가 반응의 속도론적 연구
朴茂淳,金文執,崔元植,黃善岩,孟柱煬 순천향대학교 1991 논문집 Vol.14 No.1
Reaction of benzaldehyde derivatives with ethylacetate afforded ethylbenzylidenecyanoacetate. Especially, the crystal structure of ethyl p-methoxybenzylidenecyanoacetate were demonstrated by X-ray diffrection method. The crystal structure is only exist in E-form. The kinetic studies on the mechanism of nucleophilic addition of thiophenol to ethyl benzylidenecyanoacetate have been investigated by UV-spectrophotomery and the rate equation which can be applied over wide pH range was obtained. From the rate equation, effect of generalbase and substituent, the fellowing reaction proposed. Below pH 3.0, thiophenol added to the double bond, while above pH9.0 thiophenoxide ion added to the double bond. In the range of pH from 3.0 to 9.0, these reaction occurred competitively.
( Sun Mi Lee ),( Tae Oh Kim ),( Geun Am Song ),( Cheol Woong Choi ),( Kyung Yeob Kim ),( Gwang Ha Kim ),( Jeong Heo ),( Dae Hwan Kang ),( Mong Cho ) 대한소화기학회 2007 SIDDS Vol.9 No.-
Background/Alms: Acute hemorrhagic rectal ulcer (AHRU) is a rare disorder, it is increasingly reported. This study assessed the clinical and endoscopic characteristics of AHRU and compared a group with rebleeding to a non-re-bleeding group after treatment. Methods: Twenty-three patients who underwent sigmoidoscopy or colonoscopy within 48 hours of the onset of hematochezia were consecutively enrolled from January 2004 to January 2007. The diagnosis of AHRU was made by clinical, histological and colonoscopic findings. Results: All of the patients were elderly and bed-ridden and all had a sudden onset of massive, fresh rectal bleeding without pain The characteristics of the lesions at colonoscopy were solitary or multiple rectal ulcer(s) or Diculafoy-like lesions located in the lower rectum. There were no differences observed based on mean age, gender, use of anticoagulant or antiplatelet agents, endoscopic findings and clinical outcome between the rebleeding and nonrebleeding groups. However, the performance status and the PT INR were significantly different in comparisons between the two groups (respectively p=0.024 and p=0.032). Conclusions: When massive hematochezia occurs in bedridden patients with severe comorbid illness, AHRU should be considered in the differential diagnosis.
Sun Am Kim,Sang Woong Kim,Tae Hwa Kang,Sung Ok Jang,Young Cheol Kim,Beom Ryong Kang 한국응용곤충학회 2018 한국응용곤충학회 학술대회논문집 Vol.2018 No.10
Tetranychus urticae and Myzus persicae are one of the most serious insect pests in many crops, vegetables, flowers, and fruit trees worldwide. Many insecticides have been developed to control green peach aphid and two spotted spider mite, but resistance to almost all insecticides has reduced their control effect. Particular groups of plant-beneficial microbials are not only root colonizers that provide plant disease suppression, but in addition are able to infect and kill insect larvae. Antimicrobial compounds produced by biocontrol microbes are effective weapons against a vast diversity of organisms such as fungi, nematodes, and viruses. In this study, we evaluated the effectiveness of mixtures plant extracts and improvement of culture process biocontrol microbials on insecticidal activity. Azadirachta indica and Derris elliptica mixed with micorbials, which are nutrient sources of mung bean extract and lecithin, were more effective than other the mixtures. Leaf spraying with the mixture of Pseudomonas fluorescens significantly showed the highest insecticidal power in vivo for 24 hours after treatment. The effect of spraying mixture was more than 50% at 2000 times dilution, and the spraying concentration of 90% or more showed a dilution of up to 500 times. Our results indicated that the nutrient sources of microbe act as a key antimicrobial metabolite in biocontrol of insect pests, and mixing with plant extracts can provide synergistic effects as an optimal usage of the biocontrol agents.
Kyung-Sun Bae(Kyung-Sun Bae),Ji-Ye Kim(Ji-Ye Kim),Je-Yong Yoon(Je-Yong Yoon),Gwy-Am Shin(Gwy-Am Shin) 적정기술학회 2023 적정기술학회지(Journal of Appropriate Technology) Vol.9 No.3
Despite tremendous efforts from various international agencies such as World Health Organization (WHO), waterborne diseases are a still major cause of morbidity and mortality in the world – with more than 1 billion incidences and more than 2 million deaths per year. As an effort to mitigate this global burden, we developed a water disinfection system using electrochemical mixed oxidants-generating system. This system is simple, inexpensive, and easy to use. In this study, we determined the effectiveness of the new water disinfection system against waterborne pathogens using Escherichia coli CN13, bacteriophage MS2 and Bacillus subtilis spores as bacterial, viral, and protozoa indicator organisms, respectively. The results of this study showed that the new water disinfection system is very effective against E. coli CN13 (~3 log10 inactivation within 3 minutes with 0.3 mg/L of free chlorine) and coliphage MS2 (> 4 log10 inactivation within 3 minutes with 0.5 mg/L of free chlorine) Although the inactivation of B. subtilis spores by the new disinfection system was somewhat slow (~0.5 log10 inactivation in 60 minutes with 10 mg/L of free chlorine), the result is similar to previous studies with free chlorine. Overall, the results of this study indicate that the new water disinfection system using an electrochemical mixed oxidants-generating system is easy to use, convenient to carry, and also very effective against most waterborne pathogens, so it could be a sustainable solution for providing safe drinking water to the people in developing countries.