Candida albicans에 의한 허리근 농양 1예

정승기,김수연,봉정민,백은기,이규훈,이상오,서일혜,조용균 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

칸디다는 우리 몸의 여러 곳에서 발견되는 상재 진균으로 Candida albicans가 가장 흔히 질병을 일으킨다. 대부분 표재성 감염을 일으키며 칸디다에 의한 심부 감염은 드물다. 심부 감염은 주로 면역약화 환자에서 혈류를 따라 여러 장기에 퍼지는 파종성 칸디다증으로 발생하며, 한 곳의 심부 장기에만 농양을 형성하는 경우는 상대적으로 덜 흔하다. 저자들은 당뇨병과 알코올성 간경변을 가진 환자에서 혈액 및 농 배양 검사에서 C. albicans가 동정된 허리근 농양 1예를 경험하였고 배농과 amphotercin-B, fluconazole로 성공적으로 치료하였기에 문헌고찰과 함께 보고하는 바이다. Candida species are ubiquitous human commensals, of which Candida albicans is most commonly associated with human disease. Candida infections usually involve superficial tissues, but the infections of deep tissues are relatively uncommon. Among the Candida infections of deep organs, disseminated candidiasis is the most common presentation particularly in immunosuppressed patients, however, a single abscess formation in deep organ is rare. We experienced a case of psoasabscess by C. albicans in a patient who had diabetes and alcoholic liver cirrhosis, which was treated successfully by drainage of the abscess and administration of amphotericin-B, followed by fluconazole. We report this case with review of the pertinent literatures.

경주지역 여고생의 초경과 체성장간의 관계

김준섭,권오구,박진석,오종수,박정현,박제식,안세한,이용환,서정호,신태섭,최영배,김덕수,이관,박수경 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

본 연구는 경주지역 1개 고등학교 3학년 여고생을 대상으로 초경 시작 전인 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레 수치와 초경 연령을 파악하여 여성의 초경이 빠를수록 체성장 속도의 변화가 있을 것이라는 가설을 기초로 두 요인간의 관련성을 파악하고자 시행되었다. 경주시 1개 여자고등학교 3학년생 총 317명에 대해 ㅊ경 나이, 초경시 심리 상태, 초경이 시작되었을 때의 상담 여부와 상담하였던 사람, 부모 신장과 초경전후의 식사 규칙성, 다이어트 경험, 수면시간, 스트레스, 음주/흡연 여부, 질병력 등에 대한 설문 조사를 시행하였고, 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레에 대한 정보는 건강기록부에서 확보하였다. 상기 대상자 중 건강기록부가 분실된 39명, 초경나이에 대해 응답하지 않았던 29명 및 결석 등으로 조사를 하지 못하였던 42명을 제외한 조사 대상자는 206명으로 선정하였다. 대상자들의 초경연령 평균값(Mean±SD)은 13.0±1.11이었고, 초등학교 4학년부터 고등학교 2학년까지의 초경 이후 신장 성장률은 감소하였으며, 초경연령이 빠른 군이 초등학교 때는 신장에 있어서 우위를 차지하나 고등학교에 오면서 신장은 비슷한 수준이 되었다. 초경후 1-2년 사이에 체중과 흉위의 증가율은 감소하였고, 초경연령이 빠른 군이 초등학교와 고등학교 사이에 체중과 흉위에서 모두 우위를 차지하였다. 본 연구의 결과는, 흔히 이차 성징의 시작 시점 혹은 사춘기의 시작 시점으로 보고있는 초경 연령이 청소년기의 성장과 밀접한 관련성이 있고, 특히 체중과 흉위의 성장 속도와 밀접한 관련성이 있음을 시사한다. To understand the onset of menarche in relation to changes in physical growth that take place during female adolescence, especially the changes in height and weight velocity. The 207 senior in one women high school of Kyongju were investigated in April 3 to 8, 2001. We collected the information, relation in the age at menarche, height & weight of parents, regularity of eating, and obesity diet, duration of sleeping, sickness & stress near age at menarche, by self-recording. The status of height, weight & chest circumference between the 4th grade of primary school and the junior of high school was collected by individual Health Record. The results were followed; The average age at menarche was 12.95±1.11 years old and the most frequent age of menarche is 13 years. After menarche, the velocity of height, weight and chest circumference were decreased. The most rapid group of menarche hold dominant position in height during elementary school. As time passed, they dont hold dominant position in height. The most rapid group of menarche get an advantage in the weight and the girth of chest after elementary school. The height of subjects is directly proportional to the height of their parents. These results suggest that the starting age at menestuation can be closely associated with physical growth and development.

인지도 조사에 의한 건국의대 의학과 교육목적 및 교육목표의 평가

박수경,김진국,김소정,김형수,이건세,장성훈 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

This study was conducted to survey the recognition and accuracy for educational goal and objectives of College of Medicine, Konkuk University on students and professors with using 18 items of questionnaire from May 15 through June 30, 2004. The recognition for educational goal of College of Medicine, Konkuk University in participating students and professors were 93-95%. And recognition for 3 objectives of College of Medicine, Konkuk University on participating students and professors were 84-87%, 95% respectively. However the accuracy for detail educational objectives using other college of medicine were 46-59% in first student survey, 44-67% in second student survey and 58-72% in professor survey. Therefore it is need to advertize 3 objectives to students and professors. And it is also necessary to refine the contents of educational objectives to more suggesting directions than broad goal of ideal.

運動時 心拍數와 身體造成 要因과의 關係分析

朴秀一,姜珍烘,劉德時,金正完 慶尙大學校 1986 論文集 Vol.25 No.2

The aims of this study were directed at analyzing the intorrelations between beart rates, body compositions and cardiovascular functions of men and determining multiregression equations to examine the spending time to reach the heart rates of 150beats/min and 170beats/min. For the purpose of this sturdy, Bicycle ergometer were utilized to examine heart rates of individuals and Treadmill were using to get individual index of cadio-respiratory functions. The conclusion. 1. There were significant positive correlation between Body weight and body surface area. 2. There were significant negative correlation(p<.01) between Vo2 max and VE max. 3. There were significant negative correlation(p<.05) between Maximum respiratory rate and maximum tidal volume. 4. The spending time to be reached at 150beats/min were presented to be significant negative correlation with body surface area and maxmum oxygen removal. 5. The spending time to be reached at 170beats/min were presented to be significant regative correlation with under water-weight and maximum oxygen-intake. 6. Multiregression equation for prodictrng the spending time to be reached at 150beats/min and 170beats/min were as follows. A. 150beats time = 15.8163-4.8587×under water-weight+0.1403×oxygen removal max. B. 170beats/min time = 10.5244-0.1334×body weight+5.5637×under wate-weight+11.8603×body surface area+0.1061×oxygen removal max.

Caffeic Acid의 ONOO^(-) 제거활성

이지영,성도유,노재경,김유정,제정환,김민선,최재수,정해영,이경희 대한암예방학회 2003 Journal of cancer prevention Vol.8 No.3

Differences in seroprevalence between epicenter and non-epicenter areas of the COVID-19 outbreak in South Korea

Jeong Hye Won,Chang Hyun-Ha,Kim Eun Ji,Kim Yu Kyung,Kim Se-Mi,Kim Eun-Ha,Kim Young-Il,Casel Mark Anthony B.,Kim Seong-Gyu,Rollon Rare,Jang Seung-Gyu,유광민,Kim Hee-Sung,Park Hee Sue,Park Su-Jin,Kim Yong- 한국미생물학회 2021 The journal of microbiology Vol.59 No.5

To compare the standardized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence of high epicenter region with non-epicenter region, serological studies were performed with a total of 3,268 sera from Daegu City and 3,981 sera from Chungbuk Province. Indirect immunofluorescence assay (IFA) for SARS-CoV-2 IgG results showed a high seroprevalence rate in the Daegu City (epicenter) compared with a non-epicenter area (Chungbuk Province) (1.27% vs. 0.91%, P = 0.0358). It is noteworthy that the highest seroprevalence in Daegu City was found in elderly patients (70’s) whereas young adult patients (20’s) in Chungbuk Province showed the highest seroprevalence. Neutralizing antibody (NAb) titers were found in three samples from Daegu City (3/3, 268, 0.09%) while none of the samples from Chungbuk Province were NAb positive. These results demonstrated that even following the large outbreak, the seropositive rate of SARS-CoV-2 in the general population remained low in South Korea.

Higher Physical Activity Is Associated with Increased Attentional Network Connectivity in the Healthy Elderly

Kim, Geon Ha,Im, Kiho,Kwon, Hunki,Seo, Sang Won,Ye, Byoung Seok,Cho, Hanna,Noh, Young,Lee, Jong Min,Kim, Sung Tae,Park, Sang Eon,Kim, Hojeong,Hwang, Jung Won,Kang, Sue J.,Jeong, Jee Hyang,Na, Duk L. Frontiers Media S.A. 2016 FRONTIERS IN AGING NEUROSCIENCE Vol.8 No.-

<P>The purpose of this study was to demonstrate the potential alterations in structural network properties related to physical activity (PA) in healthy elderly. We recruited 76 elderly individuals with normal cognition from Samsung Medical Center in Seoul, Korea. All participants underwent the Cambridge Neuropsychological Test Automated Battery and 3.0T brain magnetic resonance imaging (MRI). Participants were subdivided into quartiles according to the International Physical Activity Questionnaire scores, which represents the amount of PA. Through graph theory based analyses, we compared global and local network topologies according to PA quartile. The higher PA group demonstrated better performance in speed processing compared to the lower PA group. Regional nodal strength also significantly increased in the higher PA group, which involved the bilateral middle frontal, bilateral inferior parietal, right medial orbitofrontal, right superior, and middle temporal gyri. These results were further replicated when the highest and the lowest quartile groups were compared in terms of regional nodal strengths and local efficiency. Our findings that the regional nodal strengths associated with the attentional network were increased in the higher PA group suggest the preventive effects of PA on age-related cognitive decline, especially in attention.</P>

Lichen planus pigmentosus-inversus presenting as acanthosis nigricans

( Sue Jeong Kim ),( Hae Eul Lee ),( Young Lee ),( Young Joon Seo ),( Jeung Hoon Lee ),( Myung Im ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1

Lichen planus pigmentosus-inversus is a rare variant of lichen planus pigmentosus that is characterized by dark brown to violaceous macules or patches on the flexuralareas. To our knowledge, lichen planus pigmentosus- inversus presenting as acanthosis nigricans has never been reported. A 54-year-old woman presented with symmetrical ill-defined gray-brown, velvety plaques on the axillae, inframammary folds, and abdomen 3 years earlier. Clinically, it resembled acanthosis nigricans. The medical history was non-contributory and there was no weight gain. Histological examination revealed vacuolar degeneration of the basal layer and dense lichenoid lymphocytic infiltrations with dermal melanophages. Based on the histopathological features, we reached a diagnosis of lichen planus pigmentosus-inversus. The patient was treated with acitretin, cyclosporin, topical steroid, and tacrolimus; the lesions improved slightly, but remained. Here, we report a case of lichen planus pigmentosus- inversus that presented as acanthosis nigricans.

Three cases of red scrotum syndrome

( Sue Jeong Kim ),( Hae Eul Lee ),( Myung Im ),( Young Joon Seo ),( Jeung Hoon Lee ),( Young Lee ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1

The red scrotum syndrome (RSS) is a rare and chronicdisease characterized by persistent erythema of the anterior half of the scrotum. It is accompanied by itching, burning sensation and hyperalgesia. The various therapies including topical or oral corticosteroid and antifungal agents are not effective. Recently, there are some reports which showed improvement of RSS treated with doxycycline, gabapentine or amitriptyline. But so far, there are debates about which medicine could be used as first line treatment. Here, we report 3 cases of RSS successfully treated with amitryptiline. All patientscomplained about mild itching and burning sensation of scrotum and their cutaneous manifestations were characterized by well-demarcated erythematous patches of the scrotum. All patients were treated with oral amitriptyline and their itching and burning sense were improved. Dermatologist should consider red scrotum syndrome and differentiate from other disease frequently involving the genital area. In addition, we suggest to treated RSS with amitriptyline as first line treatment.

Scar sarcoidosis developed after blepharoplasty in acute lymphoblastic leukemia patient

( Sue Jeong Kim ),( Hae Eul Lee ),( Myung Im ),( Young Joon Seo ),( Jeung Hoon Lee ),( Young Lee ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1

Scar sarcoidosis is a rare form of cutaneous sarcoidosis where preexisting scars become infiltrated with non-caseating granulomas. Multiple events such as trauma, local injection, operation have been known to develop scar sarcoidosis. A 46-year-old woman presented with erythematous papules on her left upper eyelid. She was diagnosed as acute lymphoblastic leukemia (ALL) 10years ago and received blepharoplasty (double eyelid surgery) 20 years ago. To rule out the leukemia cutis, we performed the skin biopsy. Histological examination showed dense non-caseating granulomatous infiltration in entire dermis, with numerous epithelioid cells consistent with sarcoidosis. Chest X-ray and blood test showed no evidence of systemic sarcoidosis. There are several reports about the scar sarcoidosis after blepharoplasty and sarcoidosis developed in ALL patients, respectively. However, there is no report on the scar sarcoidosis occurring on blepharoplasty scar in ALL patients 20 years of after surgical procedure. When firm papules appear on the scar site in leukemia patients, the skin biopsy is needed to exclude the scar sarcoidosis.