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      저자 : ( Subha Rastogi ) (검색결과 3 건)
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      • KCI등재후보

        Pharmacognostical Evaluation of Roots of Pygmaeopremna herbacea (Roxb.) Mold.

        Subha Rastogi,Madan Mohan Pandey,Kaushal Kumar,Ajay Kumar Singh Rawat,Palpu Pushpangadan 한국생약학회 2005 Natural Product Sciences Vol.11 No.2

        Pygmaeopremna herbacea (Roxb.) Mold. (Verbenaceae) is a small herb or sometimes an undershrub arising from a perennial rootstock. The dry roots are dark muddy brown in colour having root nodules. Itsextensively developed roots are widely used in tribal medicine. They are used as an aphrodisiac and for thetreatment of gout, rheumatism and ulcers. This study deals with the detailed pharmacognostical evaluation of thedried roots and root nodules of P. herbacea which includes macro and microscopic studies, determination ofphysicochemical parameters and chemoprofiling of the extract using HPTLC fingerprint profiles. It was observedthat the roots consist of a well developed cortical region consisting of tangentially elongated thin walledparenchymatous. The HPTLC fingerprint profile of the methanolic extract showed the presence of seven majorbands. Such an analysis may thus be utilized in identifying P. herbacea and in differenciating it from other specieswhich are similar to it or are used as its adultrants/substitutes under the same vernacular name of Bharangi.

      • KCI등재후보

        Constituents of Mallotus nepalensis Muell. Arg.: a Mild CNS Depressant

        Subha Rastogi,Bishen Narain Mehrotra,Dinesh K. Kulshreshtha 한국생약학회 2004 Natural Product Sciences Vol.10 No.5

        Mallotus nepalensis (Euphorbiaceae) is a small tree found in central and eastern Himalayas, Nepal,Wallich and Sikkim. The 90% ethanolic extract of Mallotus nepalensis exhibited mild CNS depressant activity. Four compounds, lupeol (1), β-sitosterol (2), ursolic acid (3) and β-sitosterol- β-D-glucoside (4) were isolated from the 90% ethanolic extract of this plant of which 1, 3 and 4 are being reported for the first time from this specie.

      • KCI등재

        Evaluation of Pharmacognostical Characters andComparative Morphoanatomical Study of Saussurea costus (Falc.) Lipchitzand Arctium lappa L. Roots

        Ajay Kumar Singh Rawat,Madan Mohan Pandey,Subha Rastogi 한국생약학회 2007 Natural Product Sciences Vol.13 No.4

        costus (Falc.) Lipchitz syn S. lappato the family Asteraceae is a well known medicinal plant which finds wide usage in different indigenous systemsof medicine of India, China, Korea & Tibet. In different folk medicines the rots of S. costus are used to treatvarious disorders like ulcer, stomachache, malaria, leprosy, dysentery and toothache. However due to overexploitation, it has become endangered and has become the concern of different governmental bodies in India.The increasing demand of this endangered Himalayan species has resulted in a situation where it is oftensubstituted, knowingly or unknowingly, by other morphologically similar species. Arctium lappa, belonging to thesame family, is one such plant that has often been found to be present in the market samples of ‘Kuth’. Thepresent study was thus carried out and morphoanatomical characters, physicochemical as well as chemicalparameters were developed for proper identification of roots of S. costus and its differenciation from A. lappa aswell as authentication of the commercial market samples. The detailed morphoanatomical studies revealed thatroots of S. costus can be distinguished from A. lappa on the basis of some important microscopial characters eg.S. costus, were absent in A. lappa.. Besides, the HPTLCfingerprint profile showed a distinct band at Rf. 0.72 in S. costus, which was totally absent in A. lappa and a bandat Rf 0.64 in A. lappa which was absent in S. costus Chlorogenic acid, used as a chemical marker for HPTLCanalysis, was estimated to be 0.077% in S. costus as compared to 0.107% in A. lappa. Thus these detailedpharmacognostical parameters can be successfully used to distinguish between roots of S. costus and A. lappa.KeywordsSaussurea costus, Arctium lappa, ‘Kuth’, ‘Jangali Kuth’, Pharmacognosy, Chlorogenic acid

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