절수에 의한 Mongolian Gerbil 장기중량변화에 관한 분석연구

김무강,이기훈,이강이,송치원,이경열,권효정,박미선,정승혁,이행연,김명철 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-

In this study, authors measured the each organ weight of the long term water deprived Mongolian gerbil, after then we calculated the mean, standard deviation, variance coefficient of the real measured organ weight and induced the organ weight change quantity, rate of quantity, deviation between measured and theological organ weight, deviation rate, sum of deviation rate, organ weight change rate, rate of organ weight by the mathematical formula. The results obtained as follow 1. The weight of the brains, lung, and testis were abruptly decreased after water deprived until the 5th day, after then slowly decreased until the 20th day. 2. The weight of the heart was decreased gradually from the first day until the 20th day. 3. The weight of the liver was abruptly decreased until the 10th day, after then the more slowly decreased until the 20th day. 4. The weight of the thymus, spleen, kidney, and pancreas were abruptly decreased until the 15th day, after then increased slowly until 20th day but the weight of the kidney was abruptly increased from the 10th day. 5. The organ weight change rate and the rate of the each day organ weight were very diversified.

생체분해성 고분자를 이용한 사시수술용 제형개발 및 효용성에 대한 연구

민병무,김용백,김승영,김창식,박근성,길숙종,조항진,이성복,노승무,송규상,강대영,조준식,양준묵,정경수,최선웅,이진호,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

A new device, muscle clamping system was developed to facilitate exact quatifying technique A strabismus surgery, and reduce the risk of complications. The device is composed of a lower fixing body with three jaws and an upper supporting body. They are used to clip an extraocular muscle and fix it to the sclera with a single bite. Superior rectus recession on 16 rabbit eyes were performed with this new device. Conjunctival injection, muscle adhesion strength, and light microscopic findings were examined at 1, 2, 4 and 8 weeks postoperatively. The Conjunctival injection were minimal, adhesion power ranged from 420 to 600 gram gravity, which is sufficient in withstand the normal pull of human extraocular muscle. In microscopic exam, some Inflammatory cells and fibrosis were found. The new device was technically easy, fast, and accurate, so it may be useful in stabismus surgery.

재한줌머공동체의 ‘실금’과 한국사회의 다문화 수용력

유승무(Ryu, Seung-Moo),신종화(Shin, Jong-Hwa),박종일(Park Jong-il),이태정(Lee, Tae-Jeong),박수호(Park, Su-Ho) 고려대학교 아세아문제연구소 2013 亞細亞硏究 Vol.56 No.1

The purpose of this paper is to highlight, with the help of the Jumma community, a refugee community in Korea, the way in which the immigrant community is affected by the combination of the two factors, the adaptibility of the immigrants and the receptibility of Korean society. The main argument is to identify the fact that the components of the pre-state identities, which detonates the refugeefication, lead the internal differentiation of the refugee community due to the refugee’s strategy of adaptation, on the one hadn, and the characteristics of supporting organizations of the protection states, on the other. In this paper, first, the special aspects of refugees in their development are investigated, and, second, the Jumma community’s effort to keep their pre-state identities and the formative process of the Jumma community in Korea are evaluated. Thu authors identify the phenomenon of differentiation among refugees through the relationship with the supporting organizations in Korea. This division process of the refugee community possibly accelerates the dissolution and break-up of immigrant community. For this reason, the systematic management of refugees is also required. The outcome of this research includes: first, the immigrant community, which has been assumed as the united and homogeneous community, is internally evolved to different directions; second, the evolution of the immigrant community is led or strengthened by the supporting organizations in Korea which is relate to their own interests; third, the research on refugees, which has been alienated in the immigration and multiculturalsim studies for a long time, is evoked loudly; the importance of religion for the refugees’ adaptation process to the protecting country; last but not least, the Korean society is asked for its multicultural receptive policies to respect the tradition of the immigrant community and to manage their internal differentiation.

무연(無緣) 사회 현상의 사회학적 이해

유승무(Lew, Seung-Moo),박수호(Park, Su-Ho),신종화(Shin, Jong-Hwa),이민정(Lee, Min-Jung) 한국이론사회학회 2015 사회와 이론 Vol.27 No.-

이 논문은 최근 한국 사회에서 점차사회문제로 부상하고 있는 무연 사회 현상을새로운 관점에서 이해하기 위한 이론적프레임의 모색을시도하였다. 이러한 문제의식의 기저에는 일본 NHK가 무관계 사회 혹은 무연고 사회로 정의한 ‘무연 사회’라는 개념이 사회학적 맥락에서 성립 불가능한 모순된 개념임에도 불구하고 무비판적으로 사용되고 있다는 인식과 고령화나 가족 및 공동체의 해체 등을 무연 사회의 원인으로 규정하는 선행 연구들의 피상성을 극복해야 할 필요성이 자리하고 있었다. 이와 같은 문제의식을 해결하는 과정은 무연 사회 현상의 바탕에 마음의 멀어짐과 닫힘이 있음을 확인하는 것에서부터 출발하였다. 2000년 이후 14년 동안 주요 4개 일간지에 사용된 단어들의 활용 빈도와 그들 사이의 상관성을 통해 사회적 관계로서 의연(緣) 현상이 마음과 일정한 상관관계를 가지고 있으며, 연줄과 절연 및 무연고라는 단어의 사용이 정적인 관계를 보이고 있음도 확인하였다. 그리고 절연과 무연 사회 현상에는 갈등이나 트라우마 같은 마음고생의 계기가 존재하며, 관계 회복을 위한 의지와 마음의 강도에 따라 절연 상태의 유지 여부가 달라질 수 있음을 구체적 사례들을 통해 알 수 있었다. 이상의 사실들을 통해 ‘연’이라는 사회적 현상이 구체적 사회관계의 잠재성으로서 ‘포함과 배제의 상즉상입 과정’과 ‘관심과 무관심의 상즉상입’이라는 마음의 매개과정이 일정한 방식으로 결합함으로써 친근과 소원이라는 두 가지 유형의 관계로 발현하며, 대인관계와 집단관계라는 관계적 차원에 따라 모두 네 가지의 ‘연’ 유형이 나타남을 모델화하였다. 그리고 내재적, 외재적요인에 의해 촉발된 갈등상황이 축적됨으로써 발생한 마음의 실금이 관계 회복을 위한 노력의 정도에따라 우호적 관계를 복원하거나 절연상태로 전개되며, 다양한 관계에서 절연 현상이 중첩적으로 나타날때 무연 사회 현상이 나타남을 도식화할 수 있었다. 마지막으로 이 논문의 연구결과는 마음을 사회적 배제의 요인으로 도입해 사회적 배제 이론의 지평을 확장하고, ‘마음의 사회학’을 발전시키는 데 기여하고, 사회관계의 회복을 통해 무연 사회 현상의 예방 및 무연 상태의 사회적 약자들이 사회에 기여할 수 있는 방안을 모색하는 계기가 될것으로 기대한다. This paper aims at building a theoretical framework for newly understanding so-called ‘no-relationship’ society, which is emerging as a social problem in the Korean society recently. This purpose is based on the necessity of overcoming superficiality of the term, ‘no-relationship’ society from a Japanese broadcasting company, NHK, on the one hand, and of the previous literature which poins out aging society or the fragmentation of family and community as the main cause of rising ‘no-relationship’ society, on the other. Authors get this study started where there is a social fact that one’s heart(마음, 心) is distantiated from a relation with the others and closed finally, under the phenomenon of ‘no-relationship’ society. Authors also identify, with a longitudinal study of daily newspaper on the text mining technique, that the phenomenon of Yeon(연, 緣) as the social relation in the to some extent correlation with heart, at first, relational line(연줄, yeon-jool), cutting relation(절연, 切緣, jeol-yeon), and no-relationalbackground(무연고, 無緣古, moo-yeon-goh), these three words show positive relations each other in the correlation test of a statistical approach, at second. By the way, authors recognize that there are motives of psychological heart troubles, for example conflict, trauma, in the phenomenon of cutting relation and no-relationship society, on the one hand, and whether the state of cutted-relation is maintained or not, namely relationship is restored, is dependent on the strength of will and heart for reviving relations. Authors build two research models: the first one shows that two types of relations, closenss and estrangement are developed as a combinational consequence of ‘the mutual process of inclusion and exclusion’ and ‘the mutual penetration and wayout of concern and indifference’. The second one has four type of ‘relation(yeon)’ on the relational dimension of individual and group relations. Besides, draw a picture that no-relationship society appears when the cutting-relation phenomena in several relations are overlapped. There are two ways: the state of cutted-relation and the restoration of friendship. These are the result of effort to revive relations overcoming micro fragmentation of heart occurred by the accumulation of conflict caused by internal and external factors. Authors expect with the paper that the theory of social exclusion and the sociology of heart are connected by the way of introducing ‘heart’ as the factor of social exclusion and it would promote to find solutions for social minorities in the state of no-relationship and prevent them from other phenomena of no-relationship society through the restoration of social relations.

당뇨병과 동반된 화농성 간농양의 임상상 및 예후인자

오은숙,강무일,이원영,오기원,임동준,이소영,이정민,고승현,김성래,안유배,손현식,윤건호,차봉연,이광우,손호영,강성구 대한당뇨병학회 2000 임상당뇨병 Vol.1 No.1

연구배경: 감염질환은 혈관질환과 함께 당뇨병의 중요한 사망원인의 하나이며, 혈당조절이 불량할수록 감염 빈도가 증가됨은 잘 알려져 있다. 간농양의 발생이 있어서도 당뇨병은 중요한 기저질환 중의 하나이다. 일반적으로 간농양의 가장 흔한 원인균은 Escherichi coli라고 알려져 있으나, 최근 당뇨병을 가진 간농양 환자에서 Klesiella pneumoniae의 검출이 증가되고 있다. 또 최근 연구에 의하면 K.pneumonie가 간농양의 가장 흔한 원인균이며, K. pneumoniae에 의한 간농양은 K.pneumoniae 이외의 균주에 의한 간농양보다 당뇨병과 밀접히 관련되어 있다고 보고된 바 있다. 이에 저자들은 간농양 환자를 대상으로 당뇨병환자의 빈도를 알아보고, 그 원인균 및 특징을 비당뇨병 환자들의 경우와 비교해 보고자 하였다. 방법: 1992년 1월부터 1999년 6월까지 방사선학적 검사 혹은 수술에 의해 간농양이 확인되거나, 경피적 천자나 수술을 통한 배농액 배양, 혹은 혈액 검사에서 원인균이 증명된 182명의 환자를 대상으로 후향적 임상고찰을 실시하였다. 결과: 화농성 농양을 가진 167명의 환자(남:94명, 여:73명)중 당뇨병을 가진 환자는 54명 (남:30명, 여:24명)으로 32.3%를 차지하였다. 환자의 평균나이는 당뇨군에서 62.1 ± 13.4세, 비당뇨군에서는 55.1 ±15.5세로 당뇨군에서 높았으며(p=0.0021), 남녀간의 평균나이 비교 시 두 군 모두 여성의 나이가 의미있게 높았다. 비당뇨군에 비하여 당뇨군의 경우 저알부민혈증의 빈도와 aspartate transaminase가 증가되어있었다. 원인균주는 K. pneumoniae (당뇨군54%, 비당뇨군 39.1%), E. coli(당뇨군 17.5%, 비당뇨군 18.8%), Pseudomonas aeruginosa, Streptococcus viridans, Enterococcus 순이었으며 두 군간의 의미는 차이는 없었으나 K. pneumoniae의 경우 다른 균종에 비해 단독감염의 빈도가 높았다(82.8%). 사망률은 당뇨군에서 16.7%, 비당뇨군에서 7.1%로 당뇨군에서 의미있게 높았으며(p=0.019), 당뇨군에서의 사망환자는 모두 패혈증이 동반되어 있었다. 당뇨환자의 사망군은 생존군에 비해 당뇨병 이환기간이 길고 혼합감염의 빈도가 높았다(p=0.046). 검사실 소견에서는 총 빌리루빈 및 알카리성 포스파타제의 증가가 관찰되어 있었다. 결론: E. coli가 간농양의 주된 원인균이라는 기존 보고와는 달리 당뇨군과 비당뇨군 모두 K. pneumoniae가 간농양의 주된 원인균이었다. 또한 당뇨 유병기간이 길고 당뇨조절이 불량한 환자에서 혼합감염이며 총 빌리루빈 및 알카리성 포스파타제의 증가등과 같은 위험인자가 존재할 경우 사망률이 증가될 수 있으므로 이들 군에서는 적극적인 치료가 필요할 것으로 사료된다. Background: Liver abscesses are commonly associated with underlying disease, particularly diabete mellitus. The number of the liver abscesses caused by Klebslella pneumoniae in diabetic patient has been increased in Korea nowadays. This study was conducted to clarify the clinical presentation and prognostic factors of pyogenic liver abscesses, especially in diabetic patients and to determine the proportion of K. pneunomiae as a pathogen in liver abscess in Korea. Methods: Medical records of 167 patients treated for pyogenic liver abscess from January, 1992 through June, 1999 were reviewed retrospectively in detail. Major Pathogenic organism, clinical manifestations, prognostic factors, the importance of diabetes mellilus as an underlying disease and its effect on clinical features and prognosis were analyzed. Results: Among 167 cases of pyogenic liver abscess, underlying diabetes mellitus was present in 32.3%. The mean age of patients was 62.7 13.4 years in diabetic liver abscess group and 55.1 15.5 years in non-diabetic liver abscess group. Most liver abscesses were cryptogenic in origin or secondary to the billary tree diseases. The clinical presentations among the two groups were not significantly different. When compared to patients without diabetes, patients with diabetes had significantly higher proportions of hypoalbuminemia and elevated aspartate transaminase level. The most common organism of the pyogenic abscess was K. pneumoniae in both groups. Percutaneous drainage of the abscess with appropriate antibiotics was the most commonly used therapeutic modality in liver abscess. The mortality rate of diabetic liver abscess is 16.1 % and 7.1% in nondiabetic liver abscess. Complications, especially septicemla, were found more frequently in patients with diabetes than in patients without diabetes (64.8% vs 28.3%, septicemia : 31.5% vs 9.7%). The factors influencing mortality in the diabetic liver abscess were disease duration, mixed infection, presence of septicemia, elevated bilirubin and alkaline phosphatase. Conclusions: In contrast to prior report that the E. coli was the most common pathogen in liver abscess, we found that K. pneumoniae was the most common organism cultured in liver abscess. Diabetic patients have more complications and higher mortality than patients without diabetes. Early detection and proper treatment are needed to improve the outcome for diabetic patient with liver abscess.

생체분해성 망막압정을 이용한 망막고정에 대한 실험적 연구

김용백,민병무,김창식,박근성,김승영,길숙종,조항진,이성복,노승무,송규상,강대영,조준식,양준묵,정경수,최선웅,이진호,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Biodegradable retinal fixation devices obtain mechnical fixation of the retina with desirable chorioretinal scarring and with the potential for local, sustained release of antimetabolites and steroids to inhibit proliferative vitreoretinopathy. We manufactured a biodegradable retinal tack with barb that was designed in order to prevent intrusion from implantation of retinal tacks. This study was carried to evaluate the efficacy for retinal fixation and the capability for sustained release of drugs with a newly designed biodegradable retinal tack Biodegradable retinal tacks were made of polymers of glycolic acids and were designed with barbs in a shape to prevent the disinsertion. Biodegradale retinal tacks are divided into 3 parts, a conical portion that is inserted into the sclera, a cylinder portion that remains in the vitreous, and a neck portion between the pin and the cylinder. The tapered conical end was manufactured to allow easy insertion through the retina and choroid into the sclera. A cylinder portion was manufactured with a tapered angle that fixes firmly into the orifice of 19 gauge spinal needle. A neck portion, 0.4 mm in diameter, was designed to prevent disinsertion from following implantation of retinal tack. The applicator was a 19 gauge spinal needle and its orifice was prepared to 15°angle to accept the tapered cylinder portion of the retinal tack. The retinal tacks, secured in the needles, were passed through the formed vitreous and inserted into the retina, choroid, and sclera and were released by pushing the internal needle, usually within 2-3mm of the medullary ray of the posterior rabbit retina A retinal tack was placed in each of 8 pigmented rabbit eyes. Slit-lamp biomicroscopy, indirect ophthalmoscopy and fundus photography were performed periodically from 1 day to 8 weeks after surgery. Eight eyes were enucleated and studied by light microscopy at 8 weeks. Biomicroscopic evaluation of the animals revealed edemas adjacent to the retinal surfaces immediately after insertion of the biodegradable retinal tacks in all the animals. These edemas disappeared after 1 week. The first noticeable change in the size of retinal tacks was shown after 2weeks. The size of the retinal tacks gradually got smaller, decreasing to about one-half at 4 weeks and about one-third at 8 weeks. All retinal tacks remained in inserted places without any movement for an 8 week period. On light microscopy, epiretinal proliferations were seen to extend into the vitreous cavity. Cellular capsules that lined the inner aspect of the scleral defect caused by tack insertion were found. However the adjacent retina had a normal cytologic appearance and architecture in all specimens. We manufactured a biodegradable retinal tack that is designed to prevent intrusion from implantation of retinal tacks. All biodegradable retinal tacks reduce in size with time, but no retinal tacks extruded from the inserted place. The newly designed biodegradable retinal tack can be used for retinal fixation and may be used as a vehicle for the introduction of pharmacologic agents to prevent the cellular events that promote proliferative vitreoretinopathy.

Overlay 기반의 WiBro와 WLAN 이종망 연동을 위한 Vertical 핸드오버 구현 및 성능 측정에 관한 연구

이재호,류형근,강선무,이재용,김승천 한국정보사회진흥원 2007 정보화정책 Vol.14 No.3

유비쿼터스 사회를 위한 미래 네트워크는 다양한 이종 무선망이 혼합된 형태가 될 것으로 예상되고 있다. 본 논문에서는 개별 무선망의 특징을 최대한 활용하여 1,270,000㎡ 면적의 KAIST(Korea Advanced Institute of Science and Technology) 대학교 캠퍼스에 IEEE 802.16e/WiBro와 IEEE 802.11/WLAN 를 복합적으로 설치하여 건물외부에서는 WiBro, 건물내부에서는 WLAN으로 자동 스위칭 되는 Vertical 핸드오버 System을 구축하고 이동 성능을 분석하였다. 이종망 통합 과정에서 제조사 및 통신사업자의 사정으로 인하여 Mobile IP를 지원하지 않는 라우터들이 존재하였고, 특히 현재 WiBro에 사용되는 ACR(Access Control Router)은 Mobile IP를 지원하지 않기 때문에 이를 해결하기 위하여 Overlay 기반의 Mobility 기법을 적용하였다. 본 연구에서는 실제로 대규모 통신망을 구현하고, 이에 대한 성능시험을 시행한 후 handover delay 시간 분석을 통한 현장 적용 가능성 및 개선 필요사항을 도출하였다. 그 결과 이종망간 핸드오버 시간은 평균 2.58초로써 일반 데이터 서비스는 이종망간 연속성이 보장됨을 확인하였고, 음성∙영상과 같은 실시간 서비스는 중간에 지연시간이 발생하나 응용서비스 세션 자체는 유지됨을 확인하였다. The future network is forecast with the fact that the form where the various heterogeneous wireless networks. In this paper we build both IEEE 802.16e/WiBro and IEEE 802.11/WLAN network on the KAIST(Korea Advanced Institute of Science and Technology) campus(1,270,000m2) as well as established the vertical handover system which supported WLAN in the building and WiBro outside the building. A Mobile IP is considered for the efficient vertical mobility function in IEEE 802.16/WiBro and IEEE 802.11/WLAN environment. However, during the deployment of WiBro, only some of the ACRs(Access Control Router) can support the Mobile IP function. Therefore, WiBro network can not support the mobility function for the mobile node. In this paper, we implement an overlay-based Mobile IP function and measure the performance through a field trial. Moreover, we evaluate the possibility of commercial deployment and suggest areas that need to be improved. The average handover time between WiBro and WLAN was 2.58 seconds. As a result, the user application session maintained but real time applications were delayed during the handover time.

친환경건축물 인증기준의 분류체계 비교 연구

이승민,박상동,신기식,최무혁 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

Energy problem of our country is very serious and the energy import is being increased continuously. To solve the problems related to energy and environment, many countries including our country have prepared and carried out various certification programs to disseminate environmentally friendly buildings. The purpose of this study is to investigate the basics and category systems of domestic green building certification criteria and to utilize it as reference materials for developing integrated criteria applicable to all buildings.

위암 환자의 복강내 투여를 위한 Activated Charcoal-Alginate Bead 제형으로부터 Mitomycin C의 용출 거동

이진호,최선웅,서중기,김동민,정경수,오정연,김진향,노승무,민병무,김용백,김창식,박근성,강대영,송규상,양준묵,조준식,정현용,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherapy seems a logical choice for cancer chemotherapy. In this study, Mitomycin C (MMC)-activated charcoal (CH)-alginate (ALG) beads were prepared by the mixtures of CH particles adsorbed with MMC as an anti-cancer drug and aqueous alginate solution. The alginate is recognized as biodegradable, nontoxic, and biocompatible. The release of MMC from the beads in 0.1 M Tris buffer was stable and continuous until about 1 week. The MMC-CH-ALG beads can be applied in the peritoneal cavity for intraperitoneal chemotherapy since they provide a good adhesiveness on the tissue and controlled release pattern of the drugs.

Aflatoxin B_1과 Vitamin A가 發生中인 白鼠의 肝에 미치는 影響

李斗泳,朴景蘭,盧承武,金源式 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

For the study on the effect of aflatoxin B_1 and vitamnin A on the developing fetal rat liver, aflatoxin B_1(1mg/kg, Sigma Chemicals) was administered intraperitoneally on the 8th day of pregnancy and vitamin A (50,000IU/day, Sigma Chemicals) was administered orally from the 8th day of pregnancy to a day before sacrifice daily. Under ether anesthesia, removed uterus, opened the pregnant sac, and fetuses were fixed in the 10% neutral buffered formalin solution. The 5㎛ thick liver specimens were stained with H-E and the mitotic figures were counted under high power field(x400) of light microscope. The results were as followings: 1. Aflatoxin B_1 inhibited the liver cell mitosis. 2. On the 14th day of development, vitamin A inhibited the antimitotic effect of aflatoxin B_1.