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Meng-Meng Lv,Ming-Hui Tan,Li-Wen Lu,Rong-Hua Zhang,Zhi-Yong Guo,Cheng-Xiong Liu,Jin Yang,Kun Zou,Peter Proksch 한국생약학회 2018 Natural Product Sciences Vol.24 No.3
Two new polyketides, chinoketides A and B (1 - 2) with a known compound xylarphthalide A (3), were isolated from the solid medium of the endophytes from the leaves of the relic plant Distylium chinense with the "black-box" co-culture method, and the structures of two new compounds were elucidated by NMR, MS and CD spectra. And the absolute configurations of chinoketides A (1) and B (2) were determined as 2R,3R,8S and 5R,6S by calculating their ECD spectra to compare with the experimental CD spectra. Finally, the antimicrobial activities were evaluated to Erwinia carotovora sub sp. Carotovora (Jones) Bersey et al, and the results showed that compounds 1 - 3 displayed the antimicrobial activities with MIC value at 20.5, 30.4 and 10.2 mg/mL.
Phytochemistry and pharmacology of natural prenylated flavonoids
Hua-Wei Lv,Qiao-Liang Wang,Meng Luo,Meng-Di Zhu,Hui-Min Liang,Wen-Jing Li,Hai Cai,Zhong-Bo Zhou,Hong Wang,Sheng-Qiang Tong,Xing-Nuo Li 대한약학회 2023 Archives of Pharmacal Research Vol.46 No.4
Prenylated flavonoids are a special kind of flavonoid derivative possessing one or more prenyl groups in the parent nucleus of the flavonoid. The presence of the prenyl side chain enriched the structural diversity of flavonoids and increased their bioactivity and bioavailability. Prenylated flavonoids show a wide range of biological activities, such as anti-cancer, anti-inflammatory, neuroprotective, anti-diabetic, anti-obesity, cardioprotective effects, and anti-osteoclastogenic activities. In recent years, many compounds with significant activity have been discovered with the continuous excavation of the medicinal value of prenylated flavonoids, and have attracted the extensive attention of pharmacologists. This review summarizes recent progress on research into natural active prenylated flavonoids to promote new discoveries of their medicinal value.
Meng Weiying,Li Yupeng,Zhang Xiaochen,Shi Huaitao,Zhang Yu,Lv Xiao 한국항공우주학회 2020 International Journal of Aeronautical and Space Sc Vol.21 No.4
Fiber metal laminates, as the new generation of aircraft structural materials, are widely concerned by material researcher. This paper presents a study on the life prediction problems of fiber-reinforced Al–Li alloy laminates under spectrum loading by applying the cumulative damage and residual strength models. Firstly, fatigue life performance of the laminate materials is tested under different loading cases. Then, the most advanced damage accumulation and residual strength models are summarized, which is applied to composite laminates. Some models are directly abandoned because the data needed for fitting model cannot be obtained by this experiment or the model formulation is prevented directly to the application for the spectrum blocks with free loading. Meanwhile, a cumulative damage model considering residual strength is modified accordingly based on the characteristics of life prediction under spectrum loading. To study the impacts of these models on the fatigue life prediction for fiber reinforced Al–Li alloy laminate under spectrum loading, the predicted accuracy of these models will be compared by applying them to life prediction problems of 2/1 laminate and 3/2 laminate. Results show that compared with other models, modified model improves the prediction accuracy especially for 3/2 laminate.
Variable Research on Engineering Characteristics of Soybean Urease Reinforced Sand
Meng Cui,Huihui Xiong,Jun-jie Zheng,Suying Lv,Mingjuan Cui,Xiao Fu,Shangyu Han 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.8
In this study, based on soybean urease and standard sand, the unconfined compressive strength test and permeability test of four variables of urease concentration, urea concentration, calcium chloride concentration and sodium alginate content under different combinations of values were carried out, and the range analysis and variance analysis of test data were carried out. On this basis, the coupling model of unconfined compressive strength and permeability coefficient of soybean urease reinforced sand was established based on four test variables. It was found that the engineering characteristics of soybean urease reinforced sand were significantly affected by the combination of variable values. The maximum value of unconfined compressive strength under the test combination condition was 6.5 times of the minimum value, and the minimum value of permeability coefficient was only 1/4 of the maximum value. The primary and secondary order of influence variables of unconfined compressive strength was: urea concentration > calcium chloride concentration > urease concentration > sodium alginate content, and the primary and secondary order of influence variables of permeability coefficient was: urea concentration > calcium chloride concentration > sodium alginate content > urease concentration. The influence of urea concentration on unconfined compressive strength and permeability coefficient was obvious, and the influence of the other three variables was not obvious. In addition, it was confirmed that the established coupling model of unconfined compressive strength and permeability coefficient of soybean urease reinforced sand had high correlation coefficient and significant linear regression, which can be used for subsequent research and engineering application.
Meng, Xin-Yu,Liu, Juan,Lv, Feng,Liu, Ming-Qiu,Wan, Jing-Ming Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.6
Objective: To investigate the correlation between extracellular matrix protein-1 (ECM1) and the growth, metastasis and angiogenesis of laryngeal carcinoma. Materials and Methods: Forty-five samples with laryngeal benign and malignant tumors confirmed by pathology in Laiwu City People's Hospital from March 2006 to March 2011 were collected, in which there were 29 cases with laryngeal carcinoma and 16 with benign tumors. The expression of ECM1 and factor VIII-related antigens in patients with laryngeal carcinoma and those with benign tumors was respectively detected using immunohistochemical method, and the correlation between ECM1 staining grade and microvessel density (MVD) was analyzed. Results: In laryngeal carcinoma tissue, ECM1 was mainly expressed in cytoplasm, less in cytomembrane or intercellular substance. With abundant expression in the tissue of laryngeal benign tumors (benign mesenchymoma and hemangioma), ECM1 was primarily expressed in the connective tissue, which was different from the expression in laryngeal carcinoma tissue. The proportion of positive ECM1 staining (++) in patients with laryngeal carcinoma was dramatically higher than those with benign tumors (p<0.05), and that of strongly-positive ECM1 staining (+++) slightly higher. The results of Spearman nonparametric correlation analysis revealed that ECM1 staining grade in laryngeal carcinoma tissue had a significantly-positive correlation with MVD (r=0.866, p=0.000). Conclusions: ECM1 expression in laryngeal carcinoma is closely associated with tumor cell growth, metastasis and angiogenesis, which can be considered as an effective predictor in the occurrence and postoperative recurrence of laryngeal carcinoma.
Detection and quantification of phenol in liquid and gas phases using a clay/dye composite
Guocheng Lv,Shiyuan Liu,Meng Liu,Libing Liao,Limei Wu,Lefu Mei,Zhaohui Li,Caofeng Pan 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.62 No.-
In this study, an organic dye lucigenin (BNMA) was successfully intercalated into the interlayer of montmorillonite (MMT) to prevent fluorescence quenching. With its enhanced fluorescent property, the composite was fabricated into solid strips for it fast and sensitive phenol detection in both liquid and gas phases. Under proper optimizations it is anticipated that the composite would show great potential for phenol determination in real world environment such as wastewater treatment industry.
Zhou Lv,Meng Jian-Yu,Ruan Hong-Yun,Zhang Chang-Yu 한국응용곤충학회 2023 Journal of Asia-Pacific Entomology Vol.26 No.3
This study aimed to investigate the role of heat shock proteins in the response of Spodoptera frugiperda to environmental stress. Four Hsp70 genes of S. frugiperda were cloned using reverse transcription–polymerase chain reaction (RT-PCR) and their sequence characteristics were characterized using bioinformatics analysis. RTqPCR was used to detect Hsp70 at different developmental stages, in different tissues, and under varying environmental stresses (45 ◦ C, 36 ◦ C, 4 ◦ C, ultraviolet-A, and emamectin benzoate) to quantify the relative expression of this gene. Four Hsp70 genes were obtained by cloning, namely SfHsp70-1, SfHsp70-2, SfHsp70-3, and SfHsp70-like, which encode 653, 686, 638, and 627 amino acids, respectively, and all contain the three Hsp70 family signature sequences. Neighbor-joining (NJ) method was used to construct phylogenetic tree, and four Hsp70 of the S. frugiperda species were clustered with Lepidoptera. The results of real-time PCR showed that the SfHsp70s gene was specifically expressed in different tissues at different developmental stages and its expression increased considerably under nearly all environmental stresses in adults. This study shows that the SfHsp70 gene contributes to a large extent to the resistance of S. frugiperda to environmental stress.
Xie Meng,Du Jinying,Yang Kunqi,Song Shaoting,Lv Zonghui,Xu Huailiang,Wen An Xiang,Wang Qin,Jiang Yanzhi,Zhu Guangxiang,Wu Jiayun,Yao Yongfang,Ni Qingyong 한국곤충학회 2021 Entomological Research Vol.51 No.2
Leaf-rolling weevils (Coleoptera: Atelabidae) are considered to be specialists that oviposit only on one or two plant species. However, Apoderus dimidiatus can oviposit on at least five species. We aimed to determine whether A. dimidiatus females have different preferences for oviposition substrates, and whether differences in physical factors, nutrition and parasitism affected their choices. We observed the number of cradles, hatched larvae, pupae, emerging adults and parasitism rate during one breeding season. Weevils were given access to two host plant species, Rosa multiflora and Rubus ichangensis, and the leaf size and nutrient contents of the two plant species were investigated. We found that nutritional content, especially soluble carbohydrate, correlated with oviposition preference of weevils, and the more nutritious plant species, R. multiflora, was the preferred host in our experiment. Weevils can also use Ru. ichangensis and other plant species as hosts, likely to relieve the high parasitic pressure when laying eggs on a single host species.