만성 신부전증 환자의 간 실질 에코 변화 : 면역혈청학적 검사와 조직학적 검사와의 관계 Correlation with Serologic Test and Pathologic Findings

은효원,조경식,김정훈,김정곤 대한초음파의학회 2002 ULTRASONOGRAPHY Vol.21 No.3

평생교육에서 한국무용 프로그램의 만족도에 관한 연구 : 여가만족도와 생활만족도를 중심으로 Based on the satisfaction with leisure and life

정은혜,김경원 忠南大學校體育科學硏究所 2002 體育科學硏究誌 Vol.20 No.1

This study intends to compare and analyze the satisfaction scale between with leisure and with life on participating into Korean traditional dance program in the course of lifelong education. We can investigate it through two groups (87 females dance program participant; 102 non-participant) The statistical analysis techniques used for analyzing collected data in accordance with each goal of study included T-test, correlation analysis and multiple regression analysis. The obtained conclusions were as follows 1. The participation into korean traditional dance program had more or less effects on the leisure satisfaction. 2. The participation into it had positive influences on the life satisfaction. 3. The leisure satisfaction of participant females had more or less effects on their life satisfaction.

유아 교육기관의 무용교육 실태조사 연구

정은혜,정경원 忠南大學校體育科學硏究所 2002 體育科學硏究誌 Vol.20 No.1

The purpose of this study was to survey the preschool institution educators in Seoul and Daejeon, on order to document their perceptions with regard to the dance education. 400 subjects were randomly selected and 110 subjects from 49 institutions in seoul and 136 subjects from 63 institutions in Daejeon completed questionnaires. The modified questionnaire used based on the previous studies Won(1987), Park(1999) and Yi(2001). Descriptive and x^2 were used to analyze the data collected. The results of this study were following as: 1) Most of preschool institution teachers considered the concept of preschool dance instruction as creative expression activities to motivate preschool infants. 2) Dance program was provided for infants for 10 minutes to 20 minutes once a week or twice a week. Every infant actively participated in dance program. Female infants showed more interesting in the program than male ones. 3) Dance program considered of Ballet, rhythmical movement, Korean traditional dance, and folk dance. 4) Most of teacher utilized workship or terminal seminar and the cassette tape in a effort to acquire a series of dance instructional goals. Meanwhile Most of infants used to put on slippers with rubber-coated outsold, when they performed the activities of dance instruction even as sportswear of casuals. 5) Teachers motivated infants to express actively their own emotion or feeling. They found it necessary to train professional instructors in dance.

중학교 과학영재 담당교사의 PCK 요소의 특징과 관련성

김선경,민희정,방은정,백성혜 韓國英才學會 2011 영재교육연구 Vol.21 No.4

중학교 과학영재 담당교사의 수업을 관찰하여 Pedagogical Content Knowledge(PCK)의 요소 를 분석하고, 요소간의 관련성을 알아보았다. 연구 대상은 대도시 지역의 중학생 대상 영재교 육원에서 과학을 가르치는 교사 4명이었으며, 전공은 각각 물리, 화학, 생물, 지구과학이고 2 명은 전임교사, 2명은 겸임교사였다. 또한 전임교사들은 영재학생들만 가르쳤고, 겸임교사들 은 보통 일반학생들을 가르쳤고, 특별히 주 1회 영재학생들을 가르쳤다. 수업관찰, 반구조화 된 인터뷰를 실시하였으며, 문서자료를 수집하여 질적으로 분석하였다. 연구 결과, 과학영재 담당교사의 PCK 요소의 몇 가지 특징이 나타났다. 교사들의 과학교수지향은 PCK의 요소들 과 긴밀하게 상호작용하고 있었다. 교사들의 교육과정지식은 교사에 따라 상이했지만, 학습 유형의 선택은 교사의 영재 교육 및 수업의 목표와 관련되어 있었다. 또한 이러한 교육과정 지식은 학생에 대한 이해의 영향을 받았다. 교사들은 교육과정지식과 학생에 대한 이해에 따 라 수업에서 서로 다른 교수전략을 사용하고 있었다. 또한 PCK의 요소들의 관계는 밀접했으 며 방향성을 가지고 있었다. 이러한 연구결과를 바탕으로 PCK의 요소와 관계성을 설명하기 위해 사면체 모델을 제안했다. In this study, we analyzed the characteristics of Pedagogical Content knowledge(PCK)'s components through actual course of teachers of science gifted students in the middle school. For this study, four middle school science teachers of gifted students belonging to the gifted education professional organizations in a metropolis were selected, each of them was physics, chemistry, biology, and earth science teacher. Two of them were full-time teachers to teach only gifted students and two were part-time teachers who had taught general students in ordinary time and specially had taught the gifted students once a week. Qualitative data were collected through classroom observations, interviews, and documents. As a result, some unique characteristics of PCK's components were identified. The teachers' orientations to teaching science were closely correlated with PCK's components. The teachers' knowledges of science curriculum were different individually. But the decisions about type of teaching(acceleration or enrichment) were connected with the objectives of gifted education and lesson objectives. Also, the teachers' knowledges of science curriculum were influenced by the knowledge of students' understanding. Teachers used different instructional strategies according to the knowledge of science curriculum and the knowledge of students' understanding. We found that PCK's components were so closely connected and could show the direction of relationships among those PCK's components. We suggested teachers' PCK model which was named "Tetrahedron Model of PCK", to explain the characteristics and relationships of PCK's components.

보육교사의 인권의식 및 민감성이 영아권리존중 보육실행에 미치는 영향

박정미,김경은 남서울대학교 2017 남서울대학교 논문집 Vol.23 No.-

多樣한 黃芩藥鍼製劑의 安全性 및 效能에 關한 硏究

김호경,마진열,전원경,윤수영,강은정,주혜정,고병섭 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

In order to detect the safety and effect of various aqua-acupunctures from Scutellariae Radix, the modifications of boiling, filtration and dilution were employed for the manufacture of aqua-acupunctures. We injected 0.2cc of aqua-acupunctures into Joksamri(足三里) of rat, repeatedly. we compared subacute toxicity of them with saline group, distilled water(D.W.) group, acupuncture group and control group. The results were summarized as follows: 1. The groups were all healthy and alive, and there was no special abnormality in physical condition and autopsy. And there were not any toxic symptoms in repeating application of aqua-acupunctures to the rat, including changes of body weight, organ weight, haematological examination and serum biochemical test. 2. There was slight change of body weight in acupuncture group : We could see significance after 3 days (p<0.05) and after 7 days (p<0.001) in body weight loss. After 9 days, all tested groups were suppressed in body weight increment. 3. Result of organ weight: In Palking aqua-acupuncture(D-2 group), saline group and acupuncture group there were some statistical significance. Especially, acupuncture group revealed significant result in liver and spleen than aqua-acupunctures. From this result, we could suggest that the efficacy of acupuncture was preceded herbal medicine. 4. In serum biochemical test, we examined glucose(GLU), triglyceride(TG) and cholesterol(CHOL). In comparison with control group, the diluted 10 times of hwanggum aqua-acupuncture (× 10 group) was recognized significant decrease of glucose, but the diluted 100 times of Hwanggum aqua-acupuncture (× 100 group), D-2 group, saline group were confirmed significant increment. There was not any meaningful change of CHOL in all of tested group, excepting the acupuncture group was exhibited statistically significant decrease(p<0.05). In TG level all tested group except complex injection of standard compound (CPA group) and HG, there were significant value in statistically. The diluted solution was more significant decrease than Hwanggaum aqua-acupuncture(HG). The mutual relationship of components of aqua-acupuncture tended to decrease level of TG, regardless of its concentration. In acupuncture group, we gained some interesting result in meaningful decrease in TG. 5. Haematological examination showed significant increment of gramulocytes(GR) in all tested groups except Hwanggum aqua-acupuncture. And the diluted solutions of HG expressed very high increment of them(p<0.001). The GR and Mean Corpuscular Volume(MCV) of acupuncture group showed statistical significance.

통풍 환자에서의 지질대사

이은우,강기서,강수용,이한준,김경환,임정일,박철경 중앙대학교 의과대학 의과학연구소 2001 中央醫大誌 Vol.26 No.2

Objective: To evaluate hyperlipidemia, a msjor tisk factor of coronary artery disease, frequently asscoiated with gout patients, we compared the mean lipid level of gout patient with that of non-gout male and accessed statistical significance for treatment of gout patient. Method: This study ws performed in the 266 male gout outpatients of the CAU medical center, who had serum lipid level test from Apr. 1996 to Aug. 2000. Serum uric acid, total cholesterol, triglyceride, HDL -cholesterol, and LDL-cholesterol level were measured after 12 hours of fasting. The patients with high lipid level were further evaluated into each type of the hyperlipidemia through electrophoresis study, and the test results were compared with that of the non-gout male adults(40∼60yr), and the statistical significance was examined. Results : The gout patients showed high levels of total cholesterol, triglyceride, and LDL-cholesterol. Especially they showed high level of triglyceride and LDL-cholesterol which suggested as the risk factors of atherosclerosis and coronary heart disease, but shoewed low level of HDL -cholesterol. But there were no definite relations between lipid level and other factors auch as age of patient, initial uric acid ;eve; and duration od gout. Conclusion: To evaluate the risk factors of atherosclerotic change of cadriac vascular system in gout patient, screening tests of serum lipid level of the patient seem mandatory.

데빅병 치료에 사용한 Interferon β-1b의 부작용 1예

김정미,조은경,조정선,최용석,한영수,한정호,김두응,최진영 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

A 63 year-old woman who had diagnosis of multiple sclerosis complaining left hemiparesis and fluctuating decreased visual acuity in her right eye and abnormal findings in pattern shift visual evoked potentials(PSVEPs) and on T2 weighted MR scanning. We treated her subcutaneously with 250μg interferon (3-lb(ITFß -lb) every other day. There were detected pancytopenia, skin rash, and abnormal liver function test seven days after the therapy. In spite of reducing the dose of interferon injection, abnormal laboratory findings were not returned to normal. Dose adjustment of interferon-I3 for body weight or race, may be helpful to reduce the side effects.

초산 중독에 의한 범발성 혈관내 응고증: 1증례 보고

곽은경,김동자,박지영,배한익,채종민,곽정식,박태인 大韓法醫學會 1998 대한법의학회지 Vol.22 No.2

Strong corrosive acid is accidentally ingested by children or by psychiatric patients for the purpose of suicidal attempt. Late complications include chemical burn to pharyunx, perforation and stricture of upper gastrointestinal tract, respiratory insufficiencyand renal failure caused by hemoglobinuria following hemolysis. Acetic acid is difficult to ingestion large volume in a time because it is a strong irritant, provocating painful pharynx, and its autopsy case is rare. We report an autopsy case of acetic acid intoxication with acute disseminated intravascular coagulation (DIC) in several hours. We present pathogenesis of acetic acid intoxication and the associated forensic problems. A comatous 39-year-old female was admitted to emergency room 6 hours after she swallowed 90 gm of acetic acid. She was treated with gastric lavage but she was expired 9 hours after swallowing acetic acid. She was consulted to Department of Forensic Medicine of Kyungpook National University School of Medicine. She was grossly icteric and livor mortis was generally dark red. External wounds were 10 hemorrhagic lesions with 5 x 3.7cm and 3 x 2.8cm on the left arm and hand dorsum and facial abrasions. Internal gross examination revealed several purpural lesions in the gastric serosal surface and greater omentum. Microscopically, the stomach showed diffuse mucosal coagulation necrosis and intravascular hyalinized or fibrinoid thrombi in submucosal blood vessels. Liver showed necrosis of periportal area (zone I) and intracellular cholestasis around the central vein. Sections from renal tissue frequently show hemoglobin casts in the tubules and RBCs in the Bowman's capsules. Acetic acid of a remnant bottle, sampled blood and bloody necrotic tissues in the stomach were toxicologically examined in National Science Laboratory. The purity of ingested acetic acid is 98%, the concentration of acetic acid ion in blood is 734ppm and the content in gastric juice is 0.09%. In patients after acetic acid ingestion, DIC is most probably caused by procoagulants, produced by extensive acid-induced necrosis of the upper gastrointestinal tract. In this case, several purpural lesions were revealed on the arm, around facial abrasion and intravenous injection sites of the wrists. These are important to differentiate with contusion because she was battered before acetic acid ingestion. Purpurae in DIC are poorly demarcated, dark purple elevations with spreading margin but subcutaneous hemorrhage in contusion is grayish black or dark red with well demarcation (Table 2). But careful examination should be considered because traumatic hemorrhage is also exaggerated and mixed in DIC. (The Korean Journal of Legal Medicine)

Gas Chromatography를 이용한 Methoxime tert.-butyldimethylsilyl 유도체로서 α-Keto Acids의 분석에 관한 연구

金京禮,金正浩,金正漢,吳昌桓,黃恩卿 성균관대학교 약학연구소 1991 成均藥硏論文集 Vol.3 No.1

Abstract-Thirteen α-keto acids which are biochemically important were converted to methoxime(MO) derivatives with MOX and then to tert.-butyldimethylsilyl(TBDMS) derivatives using MTBS-TFA in isooctance prior to dual capillary column GC analysis. Single symmetric peaks were obtained for each MO TBDMS α-keto acids on the dual chromatograms. Optimum methoximation required heating at 60℃ for 2 hours and TBDMS derivatization required heating for 30 minutes. MO α-keto acids were stable during the tert.-butyldimethylsilylation and the methoximation of carbonyl group prevented silylation of enols. Mass spectrometric analysis of MO TBDMS derivatives was performed for structure identification. Base peaks at [M-57], intense ions at m/z=89, and weak ions at [M-15] were present in all spectra. The ions at m/z=89 were characteristic for α-keto acids.