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      • KCI등재

        Coronary Artery Stent Evaluation Using a Vascular Model at 64-Detector Row CT: Comparison between Prospective and Retrospective ECG-Gated Axial Scans

        Shigeru Suzuki,Shigeru Furui,Tatsuro Kaminaga,Akiyoshi Miyazawa,Yasunari Ueno,Kumiko Konno,Sadatoshi Kuwahara,Dhruv Mehta 대한영상의학회 2009 Korean Journal of Radiology Vol.10 No.3

        Objective: We wanted to evaluate the performance of prospective electrocardiogram (ECG)-gated axial scans for assessing coronary stents as compared with retrospective ECG-gated helical scans. Materials and Methods: As for a vascular model of the coronary artery, a tube of approximately 2.5-mm inner diameter was adopted and as for stents, three (Bx-Velocity, Express2, and Micro Driver) different kinds of stents were inserted into the tube. Both patent and stenotic models of coronary artery were made by instillating different attenuation (396 vs. 79 Hounsfield unit [HU]) of contrast medium within the tube in tube model. The models were scanned with two types of scan methods with a simulated ECG of 60 beats per minute and using display field of views (FOVs) of 9 and 18 cm. We evaluated the in-stent stenosis visually, and we measured the attenuation values and the diameter of the patent stent lumen. Results: The visualization of the stent lumen of the vascular models was improved with using the prospective ECG-gated axial scans and a 9-cm FOV. The inner diameters of the vascular models were underestimated with mean measurement errors of -1.10 to -1.36 mm. The measurement errors were smaller with using the prospective ECG-gated axial scans (Bx-Velocity and Express2, p < 0.0001; Micro Driver, p = 0.0004) and a 9-cm FOV (all stents: p < 0.0001), as compared with the other conditions, respectively. The luminal attenuation value was overestimated in each condition. For the luminal attenuation measurement, the use of prospective ECG-gated axial scans provided less measurement error compared with the retrospective ECG-gated helical scans (all stents: p < 0.0001), and the use of a 9-cm FOV tended to decrease the measurement error. Conclusion: The visualization of coronary stents is improved by the use of prospective ECG-gated axial scans and using a small FOV with reduced blooming artifacts and increased spatial resolution. Objective: We wanted to evaluate the performance of prospective electrocardiogram (ECG)-gated axial scans for assessing coronary stents as compared with retrospective ECG-gated helical scans. Materials and Methods: As for a vascular model of the coronary artery, a tube of approximately 2.5-mm inner diameter was adopted and as for stents, three (Bx-Velocity, Express2, and Micro Driver) different kinds of stents were inserted into the tube. Both patent and stenotic models of coronary artery were made by instillating different attenuation (396 vs. 79 Hounsfield unit [HU]) of contrast medium within the tube in tube model. The models were scanned with two types of scan methods with a simulated ECG of 60 beats per minute and using display field of views (FOVs) of 9 and 18 cm. We evaluated the in-stent stenosis visually, and we measured the attenuation values and the diameter of the patent stent lumen. Results: The visualization of the stent lumen of the vascular models was improved with using the prospective ECG-gated axial scans and a 9-cm FOV. The inner diameters of the vascular models were underestimated with mean measurement errors of -1.10 to -1.36 mm. The measurement errors were smaller with using the prospective ECG-gated axial scans (Bx-Velocity and Express2, p < 0.0001; Micro Driver, p = 0.0004) and a 9-cm FOV (all stents: p < 0.0001), as compared with the other conditions, respectively. The luminal attenuation value was overestimated in each condition. For the luminal attenuation measurement, the use of prospective ECG-gated axial scans provided less measurement error compared with the retrospective ECG-gated helical scans (all stents: p < 0.0001), and the use of a 9-cm FOV tended to decrease the measurement error. Conclusion: The visualization of coronary stents is improved by the use of prospective ECG-gated axial scans and using a small FOV with reduced blooming artifacts and increased spatial resolution.

      • KCI등재

        제품-서비스 통합시스템에서의 서비스 상호작용의 사회적 상황 표현기법

        김용세 ( Yong Se Kim ),( Kumiko Suzuki ),정혜지 ( He Ji Jeong ) 서울과학기술대학교 과학문화전시디자인연구소 2015 한국과학예술융합학회 Vol.19 No.-

        A Product-Service Systems (PSS) is composed of service and product element to provide values for relevant stakeholders. A typical service interaction involves providers and receivers, and respective values are provided in a social interaction. In cases, more than one providers are interacting with a receiver. In others, service interaction is happening in a public manner where social issues amang peer receivers are important. When service channel is supported by physical touchpoints, receivers would interact with products, which may interact with providers. Thus, in PSS, a various kinds of interactions occur in diverse social contexts. A simple representation method for social contexts is introduced where service providers, receivers andproducts are represented as nodes and interaction between them are represented as directed edges. Social context of several PSS examples are described with this. In booth designing and operating PSS, social context representations could be used in analyzing and comparing key aspects of social interaction types to retrieve similar cases to exploit related interaction design strategies and operation know-hows.

      • KCI등재

        Representation of Social Contexts for Service Interaction in Product-Service Systems

        Kim, Yong Se(김용세),Kumiko Suzuki,Jeong, Heji(정혜지) 한국전시산업융합연구원 2015 한국과학예술융합학회 Vol.19 No.-

        A Product-Service Systems (PSS) is composed of service and product element to provide values for relevant stakeholders. A typical service interaction involves providers and receivers, and respective values are provided in a social interaction. In cases, more than one providers are interacting with a receiver. In others, service interaction is happening in a public manner where social issues amang peer receivers are important. When service channel is supported by physical touchpoints, receivers would interact with products, which may interact with providers. Thus, in PSS, a various kinds of interactions occur in diverse social contexts. A simple representation method for social contexts is introduced where service providers, receivers and products are represented as nodes and interaction between them are represented as directed edges. Social context of several PSS examples are described with this. In booth designing and operating PSS, social context representations could be used in analyzing and comparing key aspects of social interaction types to retrieve similar cases to exploit related interaction design strategies and operation know-hows.

      • Ellagic Acid Inhibits Migration and Invasion by Prostate Cancer Cell Lines

        Pitchakarn, Pornsiri,Chewonarin, Teera,Ogawa, Kumiko,Suzuki, Shugo,Asamoto, Makoto,Takahashi, Satoru,Shirai, Tomoyuki,Limtrakul, Pornngarm Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

        Polyphenolic compounds from pomegranate fruit extracts (PFEs) have been reported to possess antiproliferative, pro-apoptotic, anti-inflammatory and anti-invasion effects in prostate and other cancers. However, the mechanisms responsible for the inhibition of cancer invasion remain to be clarified. In the present study, we investigated anti-invasive effects of ellagic acid (EA) in androgen-independent human (PC-3) and rat (PLS10) prostate cancer cell lines in vitro. The results indicated that non-toxic concentrations of EA significantly inhibited the motility and invasion of cells examined in migration and invasion assays. The EA treatment slightly decreased secretion of matrix metalloproteinase (MMP)-2 but not MMP-9 from both cell lines. We further found that EA significantly reduced proteolytic activity of collagenase/gelatinase secreted from the PLS-10 cell line. Collagenase IV activity was also concentration-dependently inhibited by EA. These results demonstrated that EA has an ability to inhibit invasive potential of prostate cancer cells through action on protease activity.

      • KCI등재

        Three-Dimensional Flexible Endoscopy Can Facilitate Efficient and Reliable Endoscopic Hand Suturing: An ex-vivo Study

        Jun Omori,Osamu Goto,Kazutoshi Higuchi,Takamitsu Umeda,Naohiko Akimoto,Masahiro Suzuki,Kumiko Kirita,Eriko Koizumi,Hiroto Noda,Teppei Akimoto,Mitsuru Kaise,Katsuhiko Iwakiri 대한소화기내시경학회 2020 Clinical Endoscopy Vol.53 No.3

        Background/Aims: Three-dimensional (3D) flexible endoscopy, a new imaging modality that provides a stereoscopic view, canfacilitate endoscopic hand suturing (EHS), a novel intraluminal suturing technique. This ex-vivo pilot study evaluated the usefulnessof 3D endoscopy in EHS. Methods: Four endoscopists (two certified, two non-certified) performed EHS in six sessions on a soft resin pad. Each sessioninvolved five stitches, under alternating 3D and two-dimensional (2D) conditions. Suturing time (sec/session), changes in suturingtime, and accuracy of suturing were compared between 2D and 3D conditions. Results: The mean suturing time was shorter in 3D than in 2D (9.8±3.4 min/session vs. 11.2±5.1 min/session) conditions and EHSwas completed faster in 3D conditions, particularly by non-certified endoscopists. The suturing speed increased as the 3D sessionsprogressed. Error rates (failure to grasp the needle, failure to thread the needle, and puncture retrial) in the 3D condition were lowerthan those in the 2D condition, whereas there was no apparent difference in deviation distance. Conclusions: 3D endoscopy may contribute to increasing the speed and accuracy of EHS in a short time period. Stereoscopicviewing during 3D endoscopy may help in efficient skill acquisition for EHS, particularly among novice endoscopists.

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