Azathioprine에 반응을 보인 류마티양 관절염에 의한 경막염(Pachymeningitis)1예

배광봉,이정호,이정찬,곽상혁,강정현,김철희,김현수,김종숙,조덕연,김삼용 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1

Rheumatoid arthritis frequently involves the cervical spine and may lead to neurologic impairement. However, direct involvement of CNS structures by inflammatory cells has been reported infrequently. The prevalence of this complication of rheumatoid arthritis is unknown. Inflammatory CNS involvement in rheumatoid arthritis reportedly occurs in the setting of longstanding, active, erosive articular disease and is accompanied by extracranial and extraspinal nodules and vasculitis. This is diagnosed by radiologic finding of CNS nodules or meningeal thickening and by biopsy or autopsy. Treatment with corticosteroid, cytotoxic agent or surgical decompression is helpful. But the majority of patients die within several months of onset of neurologic symptom. Recently, we experienced a case of pachymeningitis caused by rheumatoid arthritis, which resolved repeatedly with azathioprine treatment.

정조(正祖) 초장지(初葬地) 출토 옥의 과학적 분석 및 보존처리

이태종,오정현,김사덕,이정민,Lee, Tae-jong,Oh, Jung-hyeon,Kim, Sa-dug,Lee, Jung-min 국립문화재연구원 2013 헤리티지:역사와 과학 Vol.46 No.4

This research aims to understand the precise character of relics based on literature search and material analysis of the jade excavated from the first buried place of King Jung-jo, and to assess the level of damage through non-destructive diagnosis. Furthermore, scientific conservation treatment was used to restore the original shape of the excavated jade. According to literature search, the excavated jade is known to be jasper, but material analysis showed that it was as a serpentine with the mineral composition of antigorite. Infrared thermography analysis to assess deterioration showed that the internal damage is the result of the interstices developed along the boundary surface of the obtained jade. For conservation treatment of the damaged area on the surface, the jade was filled with a mixture of plaster and glue, and covered with a mixture of acrylic paint and gloss medium for protection, and color was adjusted. 본 연구는 정조 초장지에서 출토된 옥에 대한 문헌조사와 재질분석을 통해 유물의 재질 특성을 밝히고 비파괴진단을 통해 출토 옥의 손상도를 평가하였다. 또한 과학적 보존처리를 실시하여 출토 옥의 원형을 복원하였다. 문헌조사 결과 출토 옥은 벽옥으로 알려졌으나 재질분석 결과, 출토 옥은 안티고라이트(Antigorite) 광물조성의 사문암으로 판단된다. 열화상분석 등 손상도 평가 결과 내부손상 부분은 포획물의 경계면을 따라 발달한 간극에 의한 것으로 나타난다. 표면손상 부분의 보존처리는 석고와 아교를 혼합하여 충전하였으며 보존처리용 아크릴물감과 그로스미디엄을 혼합한 후 색맞춤하였다.

Fly Ash를 이용한 흡수제의 SO_2/NO_x 동시제거

정종현,손병현,유경선,김현규,이형근 한국화학공학회 2003 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.41 No.3

본 연구에서는 비산재를 첨가한 개량흡수제를 이용하여 황산화물과 질소산화물을 동시에 제거하기 위하여 고정층반응기 실험을 수행하였으며, 제조한 혼합흡수제는 SEM-EDX, ICP, BET, XRD 등을 이용하여 물성분석을 수행하였다. 소성한 석회석에 비산재를 혼합하여 수화시킨 'fly ash 개량흡수제'는 SO_2와 NO_x를 동시에 효율적으로 제거할 수 있었으며, 비산재를 첨가하여 제조한 개량흡수제가 첨가하지 않은 흡수제에 비하여 SO_2와 NO_x 동시제거에 더 효과적이었다. 이러한 실험결과는 석회석과 개량흡수제에 비산재의 첨가로 인하여 규산캄슘 등과 같은 수화물 생성으로 인하여 포졸란반응이 유도되어 'fly ash 개량흡수제'의 비표면적과 흡습성 등이 증가되었기 때문이다. 또한, 비산재를 SO_2 및 NO_x 동시제거용 첨가제로 활용하기 위한 비산재와 개량흡수제의 최적 첨가비율은 1:9인 것으로 나타났다. The simultaneous removal of SO_2 and NO_x by advanced absorbent from coal fly ash was examined in a packed bed reactor. Also, the physicochemical properties of prepared absorbents have been measured using ICP, BET, SEM-EDX and XRD. We have found that both SO_2 and NO_x in dimulated flue gas can be effectively removed by use of fly ash advanced absorbent which was prepared by hydration of calcined limestone with or without coal fly ash. The addition of fly ash into the absorbents can result in the highly efficient simultaneous removal of SO_2 and NO_x from simulated flue gas. This is because the addition of fly ash into limestone and advanced absorbent increases the specific surface area and hygroscopicity of fly ash advanced absorbents by pozzolanic reaction which leads to the formation of calcium silicate compounds. The test results indicated that the optimal mixing ratio of fly ash to advanced absorbent sample is about 1:9 for the effective removal of SO_x/NO_x.

VolP 서비스를 위한 SIP 기반의 호 전환 설계 및 구현

정종기,김도현 제주대학교 공과대학 첨단기술연구소 2004 尖端技術硏究所論文集 Vol.15 No.2

Recently, VoIP services are emerged as a serious alternative to the traditional telephony based on PSTN. This paper focus on implement of the call transfer using REFER method based on SIP for the VoIP supplementary service. First, when compared with the existed Also method and REFER method, REFER method has a short transfer delay. Also, we implement and verify the call transfer service using REFER method based on SIP.

전산화 신경인지기능검사(Seoul Computerized Neurocognitive Function Test)를 이용한 해독된 알코올 환자의 신경심리기능

박종익,이현정,고효정 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.5

Objectives : To demonstrate consistent and significant findings of neurocognitive functioning in detoxified alcoholics have been inconclusive. The purpose of this study was to evaluate cognitive functions in detoxified alcoholics and the relationship between neuropsychological test scores and alcohol consumption patterns. Methods : Twenty-four alcoholics, aging between 30 and 50 years, at least 4 weeks after the beginning of detoxification and 24 normal controls equated for age and education were exmained on Seoul computerized neurocognitive function tests in order to evaluate neurocognitive functions, which include attention, memory function, executive function, motor performance. Results : Compared to controls, alcoholics were more impaired on both finger tapping test (FTT, right : p<0.05, left : p<0.01), but there were no significant differences between two groups on any measures including attention, memory function, and executive function. Even though there were significantly negative associations between length of drinking history and performances on FTT with both hands (right : r=-0.55, p<0.01 ; left : r=-0.48, p<0.05) in alcohol group, multiple regression analyses showed that age and STAI contributed significantly to the prediction of FTT, ameliorating the dignostic effect. Conclusion : There was no evidence of significant declines in attention, memory, and executive functions in alcoholics compared to normal controls, except impaired motor performance functions which may be related to concurrent anxiety.

Wavelet 변환을 위한 부동 소수점 유닛 설계

김정태,박종태,이강현 조선대학교 에너지.자원신기술연구소 2000 에너지·자원신기술연구소 논문지 Vol.22 No.2

Introduction of digital communication network, such as ISDN(Integrated Services Digital Networks) and digital storage media have rapidly developed. Due to large amount of image data compression is key techniques, in still image and video using digital signal processing for transmitting and storing The method based DCT(Discrete Cosine Transform) is representative of the image compression. But recently, the image compression using DWT(Discrete Wavelet Transform) is widely studied. FPU is most important in the hardware design for DWT. In this paper, we proposed the high speed FPU(F1oating Point Unit) of DUT encoder for the image compression.

고음질 오디오를 위한 워터마킹에 관한 연구

김정태,박종태,이강현 조선대학교 에너지.자원신기술연구소 2000 에너지·자원신기술연구소 논문지 Vol.22 No.2

In this paper, we proposed the high quality digital audio watermarking algorithm in the frequency domain. The spread spectrum technique is used t o encrypted a stream of information data a s much of the frequency spectrum a s possible. It's by spreading the technique adapt well to data hiding in audio signal. We have used the perceptual model and MDCT/IMDCT for the high quality digital audio watermarking. The proposed watermark algorithm preserved high quality audio data from watermark signal.

국내에서 분리된 canine parvovirus의 구조유전자 cloning과 염기서열 분석

박종현,송재영,이중복,현방훈,안수환,전무형 충남대학교 생물공학연구소 1993 생물공학연구지 Vol.3 No.-

In this study gene encoding structural proteins of a CPV isolate was cloned and saquenced to elucidate the molecular genetical properties of the canine parvoviruses isolated from the field. Six recombinant plasmids of pEP3, p1471, p2070, pEP069, pEP338 and p14711p were constructed from the map positions 22 to 98 of RF DNA to clone the VP1 and VP2 genes of CPV-V20. Sequentialy the gene comprising 3780 nucleotides were sequenced by dideoxy chain termination method. When nucleotide sequence of gene encoding the structural proteins of CPV-V20 was compared with those of other strains, CPV-N, CPV-d and CPV-780929 published previously. DNA homologies to CPV-V20 were 99.87% with CPV-NM, 99.73% with CPV-d, 96.85% with CPV-780929 AND 98.4% with FPLV-Carl, respectively. The DNA sequence data of CPV-V20 showed seven point mutations and also deletion of 135 nucleotides from the nucleotide position 4745 to 4879 located in the 3-noncoding region of CPV-N.

대학병원의 외래진찰실 및 수술실 활용도 조사방법에 대한 연구 : 지방소재 J대학교 사례조사를 중심으로 Case study in J university hospital

오종희,권순정,김광현 대한건축학회 2004 대한건축학회논문집 Vol.20 No.3

The purpose of this study is to develop the survey method for the proper, effective space utilization and to analyze the utilization rate of the outpatient's consulting room and the operating room in the university hopsital. The utilization rate of the outpatient's consulting room could be got by the survey to investigate the outpatient's consulting room session utilization, doctor's behavior, time delay, special medical department's behavior etc. The utilization rate of the operating room could be got by the survey to investigate the every part of the process in the operation, that is operation time, preparation time, cleaning & arrangement time, eating time etc. Finally it was suggested that the department of internal medicine & rehabilitation medicine need to have more consulting room and surgery, othopedic surgery, neurosurgery need to reduce the number of consulting room. About the operating room, it was suggested that if the present utilization of the operating room got down to 90%, at least 3 more operating room would be needed.

크롬(Ⅵ)의 체내 흡수와 소실속도에 관한 연구

김현영,이성배,임철홍,이권섭,정용현,이종성,한정희,전윤석,황호순,이용묵 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.1

The CrO3 mostly used in plating. metal surface disposal, leather, cosmetic manufacturing, as an experiment material by repeatedly inhaling and exposure the male S.D. rats at a 0.00, 0.2., 0.50, 1.25 mg/㎡ concentration(particle size: 0.5-0.5 aerosol)6hours a day, 5day a week in 13weeks comparing with 2weeks, 8weeks of recovery group about the noxiousness of the experiment animal and the reduce scale of the CrO3 in the internal organ especially in blook and respiratory organ with the period of convalescent and clearance. The experiment results which we received are as follows. 1. In blood the RBC, HGB and HCT experiment, rats with 0.20, 0.50 mg/㎡ concentration showed that there were some decreases but not dependent. The kidneys absolute weight compared with control group was reduced intentionally(p〈0.05) and the lungs absolute weight compared with control group showed intentional increase(p〉0.05). 2. After the exposure of the experiment material, the whole blook, l\blood plasma and red blood cell in blood by (x): the period of convalescent, per (y); the decreasing of Cr concentration, was y=66.51 e -0.057x, y=67.2 e-0.101x, y=70.01 e-0.030 in 0.50 mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life (day)was estimated 12.0, 6086, 23.0 each. 3, After the exposure of the experiment material, the experiment animals lung, liver and kidneys by(x); the period of convalescent, per (y); the decreasing of Cr conentration, was y=1808 e-0.00493x, y=12.02e-0.0297x, y=67.61 e-0.0292x in 0.50mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life(day)was estimated 140.6, 23.3, 23.7, each, and including lung, liver with all of the experiment internal organs, the Cr clearance decreased as the exposure concentration increased.