Correlation Between Primary Si and Silicide Refinement Induced by Ultrasonic Treatment of Multicomponent Al–Si Alloy Containing Ti, Zr, V, and P

Jae‑Gil Jung,Young‑Hee Cho,Tae‑Young Ahn,Jae‑Hee Yoon,Sang‑Hwa Lee,Jung‑Moo Lee 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.5

The correlation between primary Si and silicide refinement induced by ultrasonic treatment (UST) of multicomponent Al–Sialloy containing Ti, Zr, V, and P was investigated. UST significantly refined the primary Si phase owing to cavitation-inducedwetting and deagglomeration of MgAl2O4particles. Lowering the UST finish temperature caused deterioration of the degreeof primary Si refinement, instead leading to silicide refinement. Cavitation-induced silicide nucleation on wetted MgAl2O4consumed the MgAl2O4particles, particularly in the case of primary Si nucleation. Similarly, the formation of an AlP phaseon the silicide phase reduced the nucleation efficiency of the AlP phase. Poisoning of the MgAl2O4and AlP phases by thesilicide phase was responsible for the deterioration in primary Si refinement. Room-temperature tensile strength and hightemperatureelongation were increased by UST and were dependent on the size of primary Si.

흰쥐 시상에서 Epidermal growth factor receptor면역반응 신경세포의 생후 발달에 관한 연구

박영란,정윤영,김종중,문정석,오재욱,정영욱,김주수 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

Background and Objectives : Epidermal growth factor receptor (EGFR), a 170-kDa transmembrane glycoprotein, appears to mediate epidermal growth factor (EGF) activity. Transforming growth factor-α and EGF produce their biological effects in numerous systems by stimulating the EGFR In this study, we examine the postnatal development of EGFR immunoreactivity in the different regions of the thalamus of the rat Materials and Methods : The present study is based on 28 postnatal cases of rat thalamus ranging from the day of birth, postnatal day 0 (P0) to 30 days (P3, P5, P10, P15, P20, P30), and these cases were compared with adult rat thalamus. Cryostat sections were processed free-floating with monoclonal antibody by immunohistochemistry Results : EGFR immunoreactivity in the thalamus of the rat showed very different patterns according to postnatal ages and thalamic areas. EGFR-immunoreactive cells appeared in the first two postnatal weeks, except the ventral posterior thalamic nuclei. In the early postnatal days, EGFR-immunoreactive cells appeared thalamic midline structures, increased progressively in the first two postnatal weeks, and followed mediolateral gradient. The mature patterns of EGFR-immunoreactive cells were achieved at P20 Conclusion : These data indicate that the maturation of EGFR-immunoreactive cells requires a relatively prolonged period of time to achieve an adult configuration. Many growth factors probably play protective or neurotrophic roles at EGFR-immunoreactive neurons of thalamus both young and adult rats In addition to difference in time of appearance in thalamic nuclei and developing pattern with mediolateral gradient suggest that EGFR-immunoreactivities are correlated with the appearance of the related functional.

부산지역 무균성 뇌막염 원인 바이러스의 분리 및 동정 : 1998년을 중심으로

김영희,정영기,김기순,지영미,윤재득,김병준,구평태,민상기,정구영,김만수,조경순 동의대학교 기초과학연구소 2000 基礎科學硏究論文集 Vol.10 No.1

The incidence of aseptic meningitis infection is ensuing and threatening the health of children. Enteroviruses are the major agents of aseptic meningitis and identification of virus has been a clue to diagnosis and epidemiology. The outbreak of aseptic meningitis occurred in Pusan, 1998. Patients were concentrated from April through November. Children were more susceptible than adults. Among 306 cases of specimens from stool, throat swab tested, only 7.2% were positive on virus isolation, 12 cases from stool and 10 from throat, respectively. All isolated 7 serotypes of viruses represented cytopathic effect on cultured cells. Three types of echovirus 6, 25, 30 and coxsackievirus B2, B3, B4, B6 were identified by neutralizing anti body test. Isolated coxsackievirus and echovirus were observed by an electron microscope with negative staining.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

간세포암의 고주파 열치료 후 천자침 경로를 통한 전이 1례

조영완,박석주,진한영,김준영,이재익,강명주,박정하,윤정희,박성재,지삼룡,이연재,이상혁,설상영 인제대학교 2006 仁濟醫學 Vol.27 No.-

Radiofrequency ablation(RFA), as a form of minimally invasive therapy for hepatocellular carcinoma, has become an important treatment modality. Because of limitation of surgery, RFA has become standard therapy for hepatocellular carcinoma in some situations. But there are some complications of RFA such as bleeding, infection, hematoma, adjacent organ thermal damage including intestinal perforation, needle track seeding, and so on. There are few reports in the literature that systematically evaluate the incidence of needle tract seeding and its associated risk factors. And only 2 cases of needle tract seeding of hepatocellular carcinoma after RFA were reported in Korea. We report a case of needle tract seeding of hepatocellular carcinoma after RFA.

고감도 Ames test(microsuspension assay)와 임파구 소핵시험법을 이용한 변이원성에 관한 조사 연구

안지영,김해준,윤인재,성영자,김영환,장영철 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.3

In order to evaluate the mutagenic effects of extractable indoor air pollutants (organic matters), we measured the mutagenic activities by sensitive microsuspension Ames test using new tester strains (YG 1024 and YG 1029). And additionally to evaluate the mutagenic effects on vital cell, we examined the frequencies of micronucleus appearing in lymphocytes from dye handling workers and controls. This study was conducted from Jan. to May, 1995. The extractable indoor air pollutants were collected by low volume air sampler in a general office room and 3 of dye handling factories. And the environment of general office room divided into 3 different groups according to the type of room heaters. To determine the frequencies of micronucleus appearing in lymphocytes, we sampled peripheral venous blood from 20 of dye handling workers and 20 of controls, and cultured, and then examined the lymphocytes. The results obtained were as follows: 1. The indirect mutagenic activities of extractable organic matters from suspended particulates collected in a general office room were higher than the direct one. 2. The strain YG 1024 was the most sensitive, and the increasing order of test strains that showed higher number of revertant were YG 1024, YG 1029, TA 100, TA 98. 3. In the general office room, the room using kerosene heater showed the highest mutagenecity, and the next was buthan gas heater, and non-heating room in order. 4. The mutagenic effects of suspended particulates in dye handling factories on the strain YG 1024 was 1.2 times higher than YG 1029. 5. The frequencies of micronucleus appearing in lymphocyte of the circulating blood of dye handling workers and the control were 5.65±2.97‰ and 4.65±0.97‰, respectively. And the difference was statistically significant.

한국인 인슐린 비의존형 당뇨병 및 이차성 당뇨병 환자에서 글루코키나제 유전자 변이

남재현(Jae Hyun Nam),이현철(Hyun Chul Lee),김연의(Youn Euy Kim),권석호(Suk Ho Kwon),윤용석(Yong Suk Yoon),박석원(Suk Won Park),원영준(Young Jun Won),차봉수(Bong Su Cha),송영득(Young Duk Song),이은직(Eun Jig Lee),임승길(Sung Kil Lim) 대한내과학회 1998 대한내과학회지 Vol.54 No.6

N/A Objectives: Mutations in the glucokinase (GCK) gene are considered a possible cause of maturity-onset diabetes of the young. The purpose of this study was to evaluate the contribution of this gene to the development of non insulin dependent diabetes mellitus (NIDDM), gestational diabetes mellitus (GDM) and post-renal transplantation diabetes mellitus (PTDM). Method: Identification of GCK mutation was attempted on 39 NIDDM patients, 2 GDM patients and 58 selected renal allograft recipients with PTDM and 45 normal controls. The exons in the GCK gene were examined by polymerase chain reaction (PCR), followed by analysis of single-stranded DNA conformational polymorphism (SSCP). The abnormal bands were also confirmed by DNA sequencing analysis. The exons of affected family members were also investigated for mutations of the GCK gene. Results: Two of the 58 PTDM patients (3.4%) were found to have CKK mutations. One had the mutation on exon 5 and the other on intron 7. One control subject had the mutation on intmn 9. The mutation of exon 5 was identified as a substitution of CCT (proline) for CTT (leucine) at codon 164, which has not ever reported before. The family members of the PFDM patient with mutation of exon 5 were analyzed by PCR followed by SSCP, and two of them revealed the same mutation. The abnormal band on the SSCP analysis of exon 7 was identified as the insertion of base C/T at the 39th nucleotide in intron 7. Two family members of this patients also had same band on SSCP. The one mutation of 45 normal controls was CT located at the 8th nucleotide in intron 9, which was a common polymorphism. Conclusion: We found GCK mutations in subjects with PTDM and we speculate that these mutations may be one of the contributing cause of PTDM.

활막육종

김재도,윤영민,손정환,홍영기,손영찬,박정호,Kim, Jae-Do,Yoon, Young-Min,Son, Jeong-Whan,Hong, Young-Gi,Son, Young-Chan,Park, Jeong-Ho 대한근골격종양학회 1996 대한골관절종양학회지 Vol.2 No.1

Synovial sarcoma is an uncommon malignant soft tissue tumor which usually occurs in young-aged person, and frequently involves the lower extremities. Many authors recommended wide excision, adjuvant chemotherapy and radiation therapy. The proposed factors that affect the prognosis are age, size of tumor, site of tumor in the body, depth of tumor, histologic grade and method of treatment. The purpose of the study is to analyze the factors that affect the 5-year survival rate. We retrospectively evaluated 19 cases of synovial sarcoma treated in the Kosin University Medical Center from Jan. 1982 to Dec. 1994. The overall 5-year survival rate was 47.6% and the 5-year survival rates were significantly higher(P<0.05) in the group with smaller size of mass. The significantly lower 5-year survival rates were observed in the patient with deeply located lesion and with higher histologic grade. The 5-year survival rates were higher in the patients treated with wide excision than in the patients treated with amputation. But there was no significant difference between these groups. The adjuvant chemotherapy and radiotherapy were performed. In conclusion, we suggest that the better prognosis will be observed in the patients with smaller size of tumor mass, superficially located and lower histologic grade.

Nanogenerators: Fully Rollable Transparent Nanogenerators Based on Graphene Electrodes (Adv. Mater. 19/2010)

Choi, Dukhyun,Choi, Min-Yeol,Choi, Won Mook,Shin, Hyeon-Jin,Park, Hyun-Kyu,Seo, Ju-Seok,Park, Jongbong,Yoon, Seon-Mi,Chae, Seung Jin,Lee, Young Hee,Kim, Sang-Woo,Choi, Jae-Young,Lee, Sang Yoon,Kim, Jo WILEY-VCH Verlag 2010 ADVANCED MATERIALS Vol.22 No.19

<B>Graphic Abstract</B> <P>The cover shows an image of fully rollable transparent nanogenerators synthesized using chemical vapor deposition grown large-scale graphene sheets as transparent electrodes and piezoelectric ZnO nanorod arrays. Sang-Woo Kim, Jae-Young Choi, and co-workers report on p. 2187 the electrical and structural stability of the nanogenerators, with excellent charge scavenging performance under external mechanical loads such as bending and rolling. This study shows that graphene-based nanogenerators are very promising for self-powered rollable transparent device applications. <img src='wiley_img_2010/09359648-2010-22-19-ADMA201090066-content.gif' alt='wiley_img_2010/09359648-2010-22-19-ADMA201090066-content'> </P>

마리오 보타의 단독주택에 나타난 보이드의 유형과 그 건축적 의미에 관한 연구

윤재희,박시영 광주대학교 2000 産業技術硏究 Vol.14 No.-

이 논문은 현대건축의 혼란한 상황 속에서 자신의 빛깔을 잃지 않고 지역성을 바탕으로 건축활동을 전개하는 건축가 마리오 보타의 단독주택에서 건축적 형태와 공간을 구성하는데 중요한 건축어휘로 나타나고 있는 보이드(Void)에 주목하여 이를 유형별로 분류하고 그것들의 특성들을 파악하여, 보이드가 지닌 형태적 의미와 공간적 의미를 연구한 것이다. 연구결과는 다음과 같다 : 1) 보이드는 보이드 자체를 감싸주는 외피의 존재유무에 따라 폐쇄형(제1유형)과 개방형(제2유형) 등 2가지 유형으로 구분할 수 있다. 2) 이러한 보이드는 유형별로 외피의 역할, 입면에 있어서 좌우대칭의 형성 역할을 담당하고 있다. 3) 보이드는 유형별로 평면상으로 주택의 정면중앙부에 위치하고 있으며 주택 배면의 계단실과 마주보고 배치되어 있는데, 주변환경에 대한 조망, 내부공간으로의 빛의 유입, 외부에서 내부로의 전이적 공간의 형성 등에 이바지하고 있다. 이러한 연구결과는 국내에서는 연구가 전무한 건축가 마리오 보타에 대한 실질적인 이해와 접근을 제공할 것이다. In the single family houses by Mario Botta, the architectural language, "void" is an important vocabulary in architectural form and space. In this study, I will analyse the void, which can be seen in the single family houses by Botta. The results of this study are as follows: 1) The void, which is seen in Mario Bottas single family house, is an important architectural vocabulary in constituting the form and space of house. This specific architectural language appears in every 16 single family houses. 2) According to the existence of an outside envelope, it is possible to classify the void in two groups, i.e. the closed type and the open type. 3) This voids contribute to form the exterior skin and the symmetry in the facade. 4) The void in the plan is located in the center of the front of the house, and it was also at a confronting relation with the staircase. It also functioned the vista into the surrounding environments, introduction of light into interior space, and formation of transition exterior into interior.