사례보고 : 하수오 복용 후 발생한 재발성 독성 간염 1예

배상훈 ( Sang Hoon Bae ),김동현 ( Dong Hyun Kim ),배영석 ( Young Seok Bae ),이광재 ( Kwang Jae Lee ),김동완 ( Dong Wan Kim ),윤정빈 ( Jeoung Bin Yoon ),홍준호 ( Joon Ho Hong ),김상현 ( Sang Hyun Kim ) 대한간학회 2010 Clinical and Molecular Hepatology(대한간학회지) Vol.16 No.2

Toxic hepatitis has been reported as a major cause of acute hepatitis, but its potential induction by herbal remedies and/or health foods is usually neglected. We experienced a case of toxic hepatitis associated with Polygoni multiflori, a Chinese herb commonly known as Ho-Shou-Wu. A 54-year-old woman consumed Ho-Shou-Wu for 1 month, after which she experienced fatigue and overall weakness. A diagnosis of toxic hepatitis was made based on her clinical history, the findings for viral markers and other laboratory data, and ultrasonography. Her condition improved considerably after she stopped taking Ho-Shou-Wu. However, she resumed taking Ho-Shou-Wu immediately after discharge from hospital, which aggravated her symptoms and liver function. She was immediately readmitted and stopped taking Ho-Shou-Wu. Her relapse into hepatitis immediate after resuming consumption of the herb is strongly indicative of the validity of Koch`s postulate in this case.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

유휴 산업시설을 활용한 국내 전시관의 재생사례 연구

김인호 ( In Ho Kim ),윤재은(교신저자,교수) ( Jae Eun Yoon ) 한국공간디자인학회 2016 한국공간디자인학회논문집 Vol.11 No.3

(연구배경 및 목적) 산업구조가 변화하면서 자연스럽게 유휴 산업시설이 생겨났고, 유휴 산업시설을 활용해 다양한 전시관 및 문화공간들이 생겨났다. 그것이 도시 재생으로 이어지고 지역경제 활성화로 이어지고 있는 것이 세계적인 추세다. 이러한 시대적 흐름에 맞추어 국내에서도 유휴 산업시설의 재생이 활발히 진행되고 있으며, 유휴 산업시설을 활용한 다양한 사례의 전시관들이 있다. 따라서 본 연구는 유휴 산업시설을 활용한 국내 전시관 사례분석을 통해 필요한 구성요소를 알아보고 앞으로 유휴 산업시설을 활용하는데 있어 기초자료를 마련하는데 목적이 있다. (연구방법) 본 연구에서는 유휴 산업시설 재생에 대한 개념과 특성 그리고 문화공간으로서의 가치에 대한 이론을 고찰하였다. 국내 사례 분석에 앞서 성공적인 해외사례지 바탕으로 한 선행논문분석을 통해 정체, 보존, 사회, 환경을 카테고리를 도출하였다. 또한 국내 사례지를 바탕으로 한 선행논문 분석을 통해 역사성, 상징성, 구조체보존, 재료보존, 참여성, 연계성, 접근성, 장소성 총 여덟 가지 키워드를 도출하였다. 앞서 나온 해외사례를 중심으로 한 논문분석에서 나온 네 가지 카테고리와 국내사례를 중심으로 한 논문분석에서 나온 여덟 가지의 키워드를 재정리하여 국내사례를 분석하고자 한다. 사례지를 선정한 기준은 지역재생 활성화의 거점의 공간으로 전시관으로 리노베이션이 되고, 지역적 특색이 명확하게 나타난 곳으로 분석의 대상으로서 유효한 가치가 있는 장소들이다. 이에 합당한 사례지는 정선 삼탄아트마인, 윤동주 문학관, 김중업 박물관, 광명 업사이클 아트센터, 인천 아트 플랫폼으로 다섯 곳으로 선정하였다. 앞서 추출한 각 4가지 분류와 총 8가지의 키워드로 분석의 틀을 설정하고 문헌연구와 현장조사를 통하여 국내의 유휴 산업시설을 활용한 전시관사례를 분석 하고자 한다. (결과) 이를 기반으로 정선 삼탄아트마인, 윤동주 문학관, 김중업 박물관, 광명 업사이클 아트센터, 인천 아트 플랫폼을 분석한 결과 정선 삼탄아트마인은 정체성과 보존도가 높은 것으로 나타났다. 윤동주 문학관에서는 전체적인보존 에서 재료 보존도를 제외하고 골고루 높은 것으로 보였고, 김중업 박물관에서는 사회분야와 환경분야 요소들이 집중적으로 높은 것으로 나타났다. 광명 업사이클 아트센터에서는 사회분야에서 참여성과 연계성이 높은 것으로 나타났고, 인천 아트 플랫폼 에서는 사회분야에서는 연계성, 환경 분야에서는 두 가지 요소 모두 높은 것으로 나왔다. (결론) 이에 본 연구에서는 유휴 산업시설이 활용되는 전시관에서는 정체성은 보존도와 서로 연관이 있고, 환경 분야는 사회분야와 서로 영향을 주는 밀접한 관계가 있는 것으로 분석되었다. 보존도가 높은 전시관에서는 역사성 그 자체가 전시의 요소로 활용 되고 있다. 이러한 요소가 전시관의 강한 정체성을 구성하며 이로 인해 관람자가 이전에 쓰였던 공간의 역사와 상징을 알 수 있고 그것이 전시관을 구성하는 정체성을 이루는 것을 알 수 있었다. 또한, 지방자치단체의 사회적 연계성과 지리적의 접근의 용이함이 지역적 활성화를 이끌어 내는 것으로 나타났다. 이는 도시재생을 위한 기틀이 되고 있음을 알 수 있었다. (Background and Purpose) The reason why industrial structure is changing, arrived so many idle industrial facilities were created. This social phenomena makes to use idle industrial facilities as the Museum or cultural space. And then this kinds of idle industrial facilities can carry over Urban Renaissance and regional economic vitalization. Nowadays, South Korea also Recovery and change idle industrial facilities to play actively, besides, already many cases of culture spaces used to idle industrial facilities in Korea. Therefore, in this research, through the national pavilion of the case analysis utilizing idle industrial facilities, examine the necessary components in order to take advantage of the idle industrial facilities, there is a purpose to prepare the future of basic data. (Method) In this study, we consider the theory of value as a concept and characteristics and cultural space for the idle industrial facilities of playback. Before analyze Korean cases, we’d analyze international cases to got four categories, that is identity, conservativeness, society, environment. also we’d extract the keyword from previous research about the idle industrial facilities of playback. That keyword is historicity, symbolism, conservation structures, preservation material, community attribute, connectivity, placeless. We’ve use that analyzed four categories and eight keyword, to analyze South Korea’s cases. This chose areas are systematically related to municipality or renovated space. The identity-clear place that has regional characteristics also can be a chosen case areas. The chosen case areas are space that is valued as a subject of analysis. These five case areas Jeongseon Samtanartmine, Yoon-dong-ju literary house, Kim-jung-up museum, Gwangmyeong epicycle art center, Incheon art platform will be researched. Now, we begin to analyze gallery characteristics with 8 keyword that broken down from precede thesis’ four classifications. (Result) Through the study, we can know that Samtanartmine has the best condition of identity and preservation. Yoon-dong-ju literary house have a good balance except preservation of materials. Kim-jung-up museum have social and environmental factors intensively. Gwangmyeong upicycle art center have good at social connectivity and community attribute, Incheon Art platform have high quality at social connectivity and environment. (Conclusion) Therefore, in this study, in the exhibition hall of idle industrial facilities have been utilized, identity, are related to each other and the field of preservation, the environment, that there is a close relationship that gives society in the field and each other to the impact It was analyzed. In the highly conserved Exhibition Hall, the historic property itself has been used as an element of the exhibition. These elements constitute a strong identity of exhibition hall, by which, onlookers can know the history a symbol of previously used space, it was found that forming the identity constituting the pavilion . Also, ease of social cooperation with geographic access local governments has been found to result in activation of the region. This was found to be the basis for urban regeneration.

자원 제약을 고려한 제안 프로젝트 포트폴리오 문제의 휴리스틱 기법

조윤재(Cho, Yoon Jae),백인섭(Paek, In Soub),김종출(Kim, Jong Chool),안태호(Ahn, Tae Ho) 한국서비스경영학회 2021 서비스경영학회지 Vol.22 No.1

With regards to the various project to establish information system in the Korean software market, a company intending to win such project considers comprehensively the business detail, expected profits, and probability to win within available resources and comes to determine if to make an offer. Such judgement is one of the most important decision making affecting the overall business management like sales and revenue. Therefore, when the proposed project portfolio is defined as the composition of the project decided to be offered among the ordered projects, Cho, Yoon-Jae(2020) suggests a mathematical model of the problem of maximizing the sum of expected values in constituting the proposed project portfolio and an optimal solution accordingly. This paper assumes the concept of a project mode to be following: 1) the resources are limited, 2) a linear progression of the probability of the orders to be awarded as the duration of each activity increases, 3) the nature of the proposed project is reflected. Unlike previous studies, this research proposes a heuristic technique as a solution to the composition of the proposed project portfolio. The simulation in this study verifies the effectiveness and efficiency of the proposed algorithm as well.

Anti-Inflammatory and Cytoprotective Effects of TMC-256C1 from Marine-Derived Fungus <i>Aspergillus</i> sp. SF-6354 via up-Regulation of Heme Oxygenase-1 in Murine Hippocampal and Microglial Cell Lines

Kim, Dong-Cheol,Cho, Kwang-Ho,Ko, Wonmin,Yoon, Chi-Su,Sohn, Jae Hak,Yim, Joung Han,Kim, Youn-Chul,Oh, Hyuncheol MDPI AG 2016 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.17 No.4

<P>In the course of searching for bioactive secondary metabolites from marine fungi, TMC-256C1 was isolated from an ethyl acetate extract of the marine-derived fungus <I>Aspergillus</I> sp. SF6354. TMC-256C1 displayed anti-neuroinflammatory effect in BV2 microglial cells induced by lipopolysaccharides (LPS) as well as neuroprotective effect against glutamate-stimulated neurotoxicity in mouse hippocampal HT22 cells. TMC-256C1 was shown to develop a cellular resistance to oxidative damage caused by glutamate-induced cytotoxicity and reactive oxygen species (ROS) generation in HT22 cells, and suppress the inflammation process in LPS-stimulated BV2 cells. Furthermore, the neuroprotective and anti-neuroinflammatory activities of TMC-256C1 were associated with upregulated expression of heme oxygenase (HO)-1 and nuclear translocation of nuclear factor-E2-related factor 2 (Nrf2) in HT22 and BV2 cells. We also found that TMC-256C1 activated p38 mitogen-activated protein kinases (MAPK) and phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathways in HT22 and BV2 cells. These results demonstrated that TMC-256C1 activates HO-1 protein expression, probably by increasing nuclear Nrf2 levels via the activation of the p38 MAPK and PI3K/Akt pathways.</P>

제조기업의 e-비즈니스 전략을 통한 공급사슬 통합에 관한 연구

윤재홍,이근호,김영수 東亞大學校 經營問題硏究所 2002 經營論叢 Vol.23 No.-

This study examines how to achieve the supply chain integration by developing e-business strategy in the manufacturing company. In order to achieve this goal, the definition of e-business was introduced, first. Second,environment analysis for developing e-business strategy was conducted. Third,the process developing e-business strategy was explained, Forth, the supply chain integration developing e-business strategy was proposed. The proposed model showed the interaction among manufacturing goals(such as cost, quality,delivery,and flexibility), e-business strategy,suppliers and customers. The model was applied for the automobile and heavy weight machine industries. This model will be helpful to enhance the competitiveness in the age of e-bussiness management.

백서의 일과성 국소허혈-재괄류 모델에서 U-74389G와 MK-801이 뇌경색 크기에 미치는 효과

김재일,김종민,양대웅,이근호,윤병우,노재규,이상복 대한신경과학회 1999 대한신경과학회지 Vol.17 No.1

임피던스 매칭과 필드 매칭을 이용한 20[GHz] Microstrip-to-CPW Transition 설계

윤재광,김동호,박종대 明知大學校 産業技術硏究所 2009 産業技術硏究所論文集 Vol.28 No.-

A compact design of 20[GHz] Microstrip-to-CPW(coplanar waveguide) transition using Impedance matching and field matching is proposed in this paper. The transition is comprise of CBCPW(conductor backed coplanar waveguide), which is connected to Microstrip and CPW for reducing reflection loss by field and impedance mismatching‘ In this paper, varying Ground shapes and via positions are offered for field and impedance matching. Because simulation and measurement results show broadband characteristic, this transition can be very useful in various UWB component MMICs and MICs.

코골이 및 폐쇄성 수면무호흡증에서 Laser-assisted Uvulopalatoplasty와 LaserUvulopalatopharyngoplasty의 치료 성적 : 장기추적관찰후 환자 만족도 조사

김재호,이윤식,박형욱,송용진,남순열,김용재,이봉재 대한이비인후과학회 2000 대한이비인후과학회지 두경부외과학 Vol.43 No.2

제조기업의 공급사슬통합과 성과

윤재홍,김영수,이근호 東亞大學校 2002 東亞論叢 Vol.39 No.-

Recently, many manufacturing companies had increased interests in supply chain integration activities between customers and suppliers and their performances. The reasons are increasing costs in manufacturing, faster life cycle of products and lack of scared resources. The purpose of this study is to search the literature about the supply chain integration activities among manufacturers, suppliers and customers. First, supply chain integration was composed of four ; logistics integration, supplier integration, purchasing integration, and information integration. Second, we try to verify the relationship between supply chain integration strategy, supply chain integration performance, and manufacturing performance. Third, we proposed the conceptual framework of supply chain integration and performance in manufacturing. This proposed model will be helpful for achieving competitive advantage and will be analyzed empirically in the near future.