非崔小 超對稱 模型에서 뉴트랄리노 質量에 關한 硏究

李峴,全禹亭 안성산업대학교 1995 論文集 Vol.27 No.-

This study is about the neutralino mass in the next-to-minimal supersymmetric standard model. In the model, there are two Higgs doublet superfields and one Higgs singlet superfield. We calculate the mass matrix of neutralino after spontaneous breaking. Then the mass matrix contains several parameters. For the reasonable set of parameters that are consistent with the present experimential deta, we calculate the neutralino mass. Finally, we expect the condition for the neutralino mass to account for the cross section.

소아에서 간질발작의 임상양상과 뇌파검사의 관계

이승현(Seung Hyeon Lee),손동우(Dong Woo Son),은병욱(Byung Wook Eun),심소연(So Yeon Sim),최덕영(Deok Young Choi),선용한(Yong Han Sun),조강호(Kang Ho Cho0, 류 일(Eell Ryoo),전인상(In Sang Jeon0, 차 한(Hann Tchah) 대한소아신경학회 2009 대한소아신경학회지 Vol.17 No.2

목적:발작의 분류는 발작의 원인, 예후를 추정하거나 항경련제를 선택하는 데 있어 매우 중요하며 뇌파검사는 발작의 종류를 구분하고 적절한 치료를 하기 위해 시행하는 중요한 검사이다. 저자들은 소아에서 임상적 발작이 확실한 경우 간질발작의 임상양상과 뇌파검사 간의 일치 정도를 알아보고자 한다. 방법:2000년 1월 1일부터 2008년 9월 30일까지 1회 이상의 간질발작을 주소로 가천의대 길병원 소아청소년과에 방문한 환자 중 본원에서 처음으로 뇌파검사를 시행한 환자를 대상으로 하였다. 발작의 임상양상은 목격자와 본인의 설명을 기록한 의무기록지를 기준으로 하여 부분발작과 전신발작으로 분류하였고 뇌파검사는 발작간간질양방전을 기준으로 정상과 비정상으로 분류하였으며 각성과 수면상태 모두에서 시행하였다. 결과:총 461명의 환자의 뇌파검사 시의 평균 연령은 6.7세였고 남자는 247명, 여자는 214명이었다. 전체 환자에서 발작의 임상양상은 부분발작이 310명, 전신발작이 187명이었다. 각성뇌파검사에서 비정상은 158명으로 부분발작파가 118명, 전신발작파가 59명, 두 가지 발작파가 한 환자에서 나온 경우가 19명이었고, 수면뇌파검사에서는 비정상이 239명으로 부분발작파가 196명, 전신발작파가 77명, 두 가지 발작파가 한 환자에서 나온 경우가 34명이었으며 전체 환자에서는 비정상이 273명으로 부분발작파가 216명, 전신발작파가 97명, 두 가지 발작파가 한 환자에서 나온 경우가 40명이었다. 간질증후군은 전체 환자 중 90명에서 관찰되었다. 146명(41.5%)의 부분발작과 44명(23.4%)의 전신발작 및 79명(87.8 %)의 간질증후군이 뇌파소견과 일치하였다. 결론:영유아 및 소아에 있어 발작을 진단할 때에는 발작양상 분 아니라 정확한 뇌파소견을 세심하게 고려하여야 한다. Purpose:Electroencephalography(EEG) is an essential method carried out for classifying seizures and taking appropriate treatment. The aim of this study is to investigate the concordance between clinical findings of epileptic seizures and EEG in children. Methods:We enrolled 461 patients from those who visited Gil hospital from January 1, 2000 to September 30, 2008 with the chief complaint of epileptic seizure more than once and checked their first EEG at the same hospital. The clinical findings of seizure were based on the charts and interictal waking and sleep EEGs were done. Results:The mean age of the patients was 6.7 years old. 497 epileptic seizures occurred and its clinical finding included 310 of partial seizures and 187 of generalized seizures. In 315 waking EEG 158 were abnormal including 118 of partial seizures, 59 of generalized seizures and 19 of both seizures, in 431 sleep EEG 239 were abnormal including 196 of partial seizures, 77 of generalized seizures and 34 of both seizures, and in waking and/or sleep EEG 273 were abnormal including 216 of partial seizures, 97 of generalized seizures and 40 of both seizures. Epileptic syndromes were observed in 90 patients. 146(41.5%) of partial seizures, 44(23.4%) of generalized seizures, and 79(87.8%) of epileptic syndromes accorded with EEG. Conclusion:When diagnosing seizures in children, we must consider not only clinical findings but also accurate EEG findings.

[P321] Kaposi`s sarcoma in a patient with HIV-associated Burkitt lymphoma

( Hyeon Woo Jeon ),( Seung-ji Kang ),( Jee-bum Lee ),( Seong-jin Kim ),( Seung-chul Lee ),( Young Ho Won ),( Sook Jung Yun ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

The development of Kaposi`s sarcoma has been associated with HIV, HSV or other immunodeficiency. There are three acquired immune deficiency syndrome (AIDS)-defining malignancies: Kaposi`s sarcoma, non-Hodgkin lymphoma of high-grade pathologic type and of B cell or unknown immunologic phenotype, and invasive cervical carcinoma. Kaposi`s sarcoma remains the most common malignancy among HIV-infected patients and Burkitt lymphoma is one of most common non-Hodgkin lymphomas in HIV-infected patients. However, cases of Kaposi`s sarcoma with Burkitt lymphoma in HIV-infected patients has been rarely reported. A 72-years-old male with HIV associated Burkitt lymphoma, Stage IV was consulted to our departement. He presented with tender purpuric patches and plaques with swelling on the abdomen and thigh, which appeared 3 weeks ago. Histopatholgic examination showed nodular pattern composed of spindle, epithelial cells with endothelial cell proliferation and RBC extravasation. Immunohistochemical stains for Human herpes vires-8, D2-40, CD31 were positive. Based on clinical findings and histologic features, Kaposi`s sarcoma was diagnosed. As the lesions showed rapid evolution, 20 cycles of radiation treatment was done for treatment of Kaposi`s sarcoma. As far as we know, this is the first case in Korean literature. We report a rare case of Kaposi`s sarcoma with HIV-associated Burkitt lymphoma.

P129 Effects of citron essential oils on VEGF, TRPV1, IL-8 release from normal human epidermal keratinocytes stimulated with TNFα

( Hyeon Woo Jeon ),( Soo Hyeon Bae ),( Sook Jung Yun ),( Seung-chul Lee ),( Jee-bum Lee ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Citron is well-known for it’s abundant antioxidative ingredients such as vitamin C, polyphenol compounds, and limonoids. Objectives: We aimed to evaluate the anti-oxidant and anti-inflammatory activities of citron essential oils on the activated keratinocytes in vitro. Methods: We used normal human epidermal keratinocytes (NHEKs) derived from neonatal foreskin. In order to evaluate the antioxidant activities of citron, DPPH radical scavenging activity, intra- and extracellular ROS generation and expressions of anti-oxidant enzymes (HO-1, Prx-1, CAT, SOD-2; Mn-SOD) were analyzed. Also, to evaluate the anti-inflammatory activity of citron essential oils on epidermal cells, NHEKs were stimulated with TNFα and vascular endothelial growth factor (VEGF), transient receptor potential vanilloid 1 (TRPV1), IL-8 were induced. These mediators were analyzed after treatment of citron seed and unripe citron oils, and also EGCG as a control. The analysis was performed by semi-quantitative RT-PCR, immunocytofluorescence and ELISA. Results: mRNA and protein levels of VEGF, TRPV1, and IL-8 of activated keratinocytes were suppressed by citron seed and unripe citron oils. Conclusion: These results show that citron essential oils possess both anti-inflammatory and anti-angiogenic properties, which indicate that this agent may be a valuable adjuvant treatment candidate for rosacea.

Multiple skin appendage tumors arising from nevus sebaceus

( Hyeon Woo Jeon ),( Jee Bum Lee ),( Seong Jin Kim ),( Seung Chul Lee ),( Young Ho Won ),( Sook Jung Yun ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Nevus sebaceus (NS) is a congenital hamartoma with epidermal, follicular and apocrine elements. Several skin appendage tumors can be evolved secondarily from NS. Although two different tumors often develop simultaneously on the lesion, it is rare to see more than two different tumors developing on the lesion of NS. We have experienced a case of NS with multiple appendage tumors on the face of a 76-year-old female. She presented for multiple black and yellowish to reddish nodules within a yellowish 8.4 x 4 cm sized solitary verrucous plaque on the left preauricular area. A large verrucous plaque was born, and black & yellowish papules had developed during recent 5 months. Histopathologic examination showed findings of different kinds of tumors. Black nodules were diagnosed as trichoblastomas showing tumors with basaloid cell with many melanin pigments with peripheral palisading pattern. Tumors of follicular infundibulum appeared as black plaques, revealing a platelike growth of anastomosing epithelial cells in the upper dermis extending parallel to the epidermis and showing multiple connections with the lower margin of the epidermis. Sebaceous hyperplasia was also diagnosed.. Sebaceoma appeared as orange colored nodules, showing well circumscribed nodule composed of many basaloid cells and some sebocytes. The remnant lesion of NS has been observed regularly. We report a rare case of NS accompanied with three different appendageal tumors.

P046 Mortality and comorbidity profiles of patients with bullous pemphigoid

( Hyeon Woo Jeon ),( Sook Jung Yun ),( Seung-chul Lee ),( Young Ho Won ),( Jee-bum Lee ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Bullous pemphigoid (BP) is the most common autoimmune-mediated blistering skin disease and significantly associated with mortality and morbidity. However, few studies about mortality and comorbidity profiles of BP has been reported in Korea. Objectives: To evaluate the mortality and comorbidity profiles of BP patients visited our clinic, in comparison to that of an age-matched general population of Korea Methods: We retrospectively evaluated 103 patients diagnosed with BP between 2006 and 2013 at Chonnam National University Hospital in Gwangju, Korea. Results: The 1-year, 2-year. and 5-year mortality rates of BP patients were 18.45%, 28.16%, and 46.15%. The median age was 74 years (rage, 41-96 years). The 5-year standardized mortality ratio (SMR) of patients with BP was 2.37 times higher than for the age-matched general population of Korea. Old age at the time of diagnosis, heart disease, dementia, stroke, osteoporosis, kidney disease and heart disease were associated with increased mortality. Also, prevalence of diabetes, stroke, dementia and Parkinson’s disease in BP patients was higher than that in general population. Conclusion: The mortality of patients with BP is higher than that of general population. Risk factors for increased mortality include medical comorbidities, especially stroke, diabetes, neurological, cardiac, renal diseases. And Patients with BP are more likely to have neurological diseases, diabetes and stroke.

A case of rowell syndrome

( Hyeon Woo Jeon ),( Sook Jung Yun ),( Jee-bum Lee ),( Seong-jin Kim ),( Seung-chul Lee ),( Young Ho Won ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Rowell syndrome is a rare disease consisting of erythema multiforme-like lesions associated with lupus erythematosus. The syndrome occurs mostly in middle-aged women. It is a very controversial condition and though defining diagnosing criteria exist, many previously published cases lack one or more of these criteria. A 43-years-old female with systemic lupus erythematosus was consulted to our department. She presented with mildly pruritic erythematous targetoid patches and plaques on face, neck and back, which appeared 6 months ago. Histopatholgic examination showed lichenoid inflammation with vascular change and interstitial infiltrate. Laboratory evaluation revealed positive speckled antinuclear antibodies, anti-Ro/SS-A antibodies and anti-La/SS-B antibodies. Based on clinical findings, histologic features and laboratory findings, Rowell syndrome was diagnosed. We report a rare case of Rowell syndrome.

Mortality and Comorbidity Profiles of Patients with Bullous Pemphigoid in Korea

( Hyeon Woo Jeon ),( Sook Jung Yun ),( Seung-chul Lee ),( Young Ho Won ),( Jee-bum Lee ) 대한피부과학회 2018 Annals of Dermatology Vol.30 No.1

Background: Bullous pemphigoid (BP) is a common autoimmune- mediated blistering skin disease that is significantly associated with mortality and morbidity. However, few studies regarding the mortality and comorbidity profiles of BP have been reported in Korea. Objective: To evaluate and compare the mortality, comorbidity profiles, and risk factors between patients with BP who visited our clinic and an age-matched general population of Korea. Methods: We retrospectively evaluated 103 patients diagnosed with BP between 2006 and 2013 at Chonnam National University Hospital in Gwangju, Korea. Results: The 1-year, 2-year, and 5-year mortality rates of the patients were 18.44%, 28.16%, and 42.00%, respectively. The median age was 76 years (range, 41∼96 years). The standardized mortality ratio of patients with BP was 1.83 times that of the age- and sex-matched general population of Korea. Old age at the time of diagnosis, cardiac disease and renal disease were associated with increased 5-year mortality. In addition, the prevalence of diabetes, stroke, dementia, and Parkinson’s disease was higher among BP patients than in the general population. Conclusion: The mortality rate of patients with BP is higher than that of the general Korean population. Korean patients with BP are more likely to have dementia, Parkinson’s disease, diabetes, and stroke. Risk factors for increased 5-year mortality include old age at the time of diagnosis and medical comorbidities, especially cardiac disease and renal disease. (Ann Dermatol 30(1) 13∼19, 2018)

Clinicopathological analysis of pigmented contact dermatitis caused by henna dyeing

( Hyeon Woo Jeon ),( Jee-bum Lee ),( Seung-chul Lee ),( Young Ho Won ),( Sook Jung Yun ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: Henna is a natural dye made from the leaves of the tree Lawsonia inermis, and it has a very low allergic property. But recently, cases of pigmented contact dermatitis (PCD) after henna dyeing (HD) are increasing. Objectives: To analyze the clinical and histopathologic features of PCD caused by HD. Methods: We retrospectively reviewed the clinical and histopathologic features of patients diagnosed with PCD after HD from June 2014 to August 2017. Results: A total of 22 patients with a history of HD were included. All patients were female, and mean age was 58.9 years. They presented with rapidly spreading dark brownish patches and there location was mostly adjacent to the hairline, such as forehead, temple, lateral portion of cheek. The mean duration between symptom onset and HD was 4.52 months (0-15). Standard patch test and as is test using henna showed no significant results. There were 18 patients with pruritus, which was only present at the early stage. The histopathologic examination of these patients showed lichenoid dermatitis with inflammation and melanin incontinence in common. Conclusion: These results suggest that the PCD after HD was caused by the toxicity of henna itself, not by other additives. The active ingredient of henna is lawsone (2-hydroxy-1, 4-naphthoquinone), which may induced lichenoid dermatitis like other agents inducing lichenoid drug eruption. Dermatologist should consider HD as the cause of pigmentation of the face and neck.

A new structure for the flexible intelligent electronic device (IED)

Hyeon-Jin Jeon,Shin-Wook Kim,Min-Woo Park,Woo-Geun Lee,Tae-Gyu Chang 대한전자공학회 2009 ITC-CSCC :International Technical Conference on Ci Vol.2009 No.7

This paper proposes a new intelligent electronic device (IED) structure which provides a full reconfigurability for the power system and allows a substation server to easily cope with faults and to control efficiently the distributed IED platforms. The proposed structure is aimed to ensure transmission latency being less than 1.0 % of sampling interval for a real-time protection. The proposed structure is implemented and its feasibility is verified by simulations.