자연산 점몰개, Squalidus multimaculatus Hosoya et Jeon의 새인두흡충, Clinostomum complanatum (Rudolphi, 1814) 감염

박명애 ( Myoung Ae Park ),서정수 ( Jung Soo Seo ),정승희 ( Sung Hee Jung ),최희정 ( Hee Jung Choi ),전은지 ( Eun Ji Jeon ),지보영 ( Bo Young Jee ),이완옥 ( Wan-ok Lee ),우승호 ( Sung Ho Woo ),이은혜 ( Eun Hye Lee ) 한국어병학회 2011 한국어병학회지 Vol.24 No.2

경상북도 영덕군의 하천에 서식하는 점몰개 spotted barbel gudgeon (Squalidus multimaculatus Hosoya et Jeon)의 근육에서 새인두흡충 Clinostomum complanatum (Rudolphi, 1814)의 피낭유충이 발견되었다. 감염된 점몰개는 "yellow grub"인 기생충의 피낭유충으로 인해 표면이 울퉁불퉁하게 보였으며, 수면위에 힘없이 유영하였고 일부 폐사한 개체도 발견되었다. 분리된 탈낭유충의 형태는 혓바닥 모양이었으며, 크기는 2.85~5.89 mm×0.8~1.99 mm였다. 어체당 1~98 개의 피낭유충을 분리하였으며 평균 감염수는 25개로 나타났다. 특히, 성어크기인 평균 7 cm 정도의 점몰개는 100% 감염되어 있었다. 본 연구는 한국의 자연수계에 서식하는 어류에서 C. complanatum 의해 질병이 발생하고 폐사가 일어난 첫 보고이다. The metacercariae of Clinostomum complanatum (Rudolphi, 1814) were isolated in the whole body muscle of wild freshwater fish, spotted barbel gudgeon (Squalidus multimaculatus Hosoya et Jeon) from the local river in Yeongdeok, Gyeongsangbuk-do, Korea. The infected fish with bumpy body surface by "yellow grub" showed erratic swimming behavior and some fish were died. The isolated excysted metacercariae were tongue shaped and 2.85~5.89 mm × 0.8~1.99 mm in size. 1~98 metacercariae were isolated in individual fish and mean infection intensity was 25. All examined adult spotted barbel gudgeon sizing 7 cm in body length were infected. This is the first report of disease outbreak and mortality caused by C. complanatum infection in wild freshwater fish in Korea.

포스트 모던(Post Modern) 패션 연구 : 1990년대 컬렉션에 나타난 전통와 현대의 조화를 중심으로 focused on the harmony of tradition and contemporary in '90s collections

전정희,박혜원 창원대학교 생활과학연구소 1998 생활과학연구 Vol.- No.2

The purpose of this study is to examine post modern fashion, especially focussed the harmony of tradition and conteporary in domestic and abroad collections in 1990's. Using analyses and examination with the fashion literature, trend informations, visual materials and internet fashion sites related to Post Modernism and Post Modern fashion. The results are as follow: Collection of outside the country are presented for harmony of style, harmony of material, utilization of ornament motive. Trend design of inside the country are presented to search for new fashion from inspiration of the past. Through the post modern fashion in represented of domestic and outside of the country 1990's collections, new creative fashion designs can be confirmed that they are produced from the harmony of tradition and modern.

CT flouroscopy를 이용한 중재적 시술의 유용성

전혜정,박정희,서보경,박상우,신현준,최영철,한혜승,이창희 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

Conventional CT-guided needle localization has been reported many times, but a few reports of interventional procedures by using multidetector CT scan with CT-fluoroscopy have been described. We presented 36 cases of CT-fluoroscopy guided interventional procedures focusing on the puncture technique. Two cases of small pneumothorax and one case of pulmonary hemorrhage out of 2lcases after lung biopsy, were not needed any treatments We can easily and accurately access to the lesion by using CT-fluoroscopy and unique our marker system.

Retinol 국소도포에 의한 눈가주름 제거효과

전희대,이성열,이혜진,박영립,이종석,황규왕 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

In 3 months randomized, double-blind, vehicle-controlled study of retinol (vitamin A 0.1%-3000IU/g) in the treatment of photoaging skin, especially eye wrinkles. 24 patients applied retinol contained cream to the both eye wrinkles and vehicle cream(placebo) to the same site. Half of the patients received retinol contained cream and half received vehicle cream(placebo). All 24 patients who completed the study showed statistically significant improvement in photoaging eye wrinkles on the retinol contained cream treated group, but not on the vehicle treated group. Eight of the 12 patients who received retinol contained cream to eye wrinkles had improvement in photoaging, whereas only three of the 12 patients who received vehicle cream(placebo) improved. In retinol contained cream group, there is a some relationship between water contents and effects. In other words, as water contents were the higher, effects were the better. The side effects were limited to mild irritation of retinol contained cream treated skin. Retinol contained cream appeared to be safe and effective in the treatment of eye wrinkles.

한국산 감잎의 Polyphenol 화합물의 생리활성물질의 화학구조 및 효소저해효과

안봉전,최희진,손준호,우희섭,한호석,박정혜,손규목,최청 한국식생활문화학회 2003 韓國食生活文化學會誌 Vol.18 No.5

The lyophilization of the solution extracted from 60 percent of acetone applied to persimmon leaves, the compounding process in accordance with the solution's concentration, and the gel filteration through Sephadex G-50 of biologically activated substances obstructing enzyme activity, such as tyrosinase, xanthine oxidase, and angiotesin converting enzyme (ACE) led to the assumption that polyphenol was the compound serving as biologically activated substances obstructing enzyme activity. Xanthine oxidase involved in pruine metabolism oxidizes hypoxanthine to xanthine and xanthine to uric acid. In the continuous study for natural compound, nine flavan-3-ois have been isolated from the persimmon leaves. The structures of (+)-catechin, (+)-gallocatechin, procyanidin B-1, pyrocyanidin C-1, prodelphinidin B-3, gallocatechin-(4α→8)-catechin, procyanidin B-7-3-O-gallate, procyanidin C-1-3'-3''-3'''-O-trigallate and (-)-epigallocatechin-(4β→8)-epigallocatechin-(4β→8)-catechin were established by NMR and their inhibitory effect on xanthine oxidase activity was investigated. Procyanidin C-1-3'-3''-3'''-O-trigallate showed 94%, 90.69%, 80.90% inhibition at 100(μ)M and inhibited on the angiotension converting enzyme respectively. Procyanidin B-7-3-O-gallate and procyanidin 1-3'-3''-3'''-O-trigallate showed 66%, 63% inhibition at 100(μ)M and inhibited on the xanthine oxidase competitively. Procyanidin C-1-3'-3''-3'''-O-trigallate showed 70% inhibition at 100(μ)M inhibited on the thyrosinase competitively.

흰쥐 성장기간에 따른 Xylene의 독성에 관한 연구

이혜자,이상희,전태원,이상일,윤종국 대한의생명과학회 2000 Journal of biomedical laboratory sciences Vol.6 No.3

실험동물에 있어서 연령 차이에 따라서 xylene 독성이 어떠한 차이가 있는지를 검토하는 일환으로 5주령 및 12주령 흰쥐에 50% m-xylene을 체중 100 g 당 0.25 ml씩 1회 투여한 다음 24시간 후에 처치하여 다음과 같은 결과를 얻었다. Xylene 투여로 인한 요 중 methylhippuric acid 함량은 5주령군이 12주령군에 비해 현저하게 높게 나타났다. 그리고 간조직 중 cytochroms P-450 함량은 대조군에 있어서 5주령군이 12주령군 보다 약 50% 정도 낮게 나타났으나 xylene 투여로 인한 cytochrome P-450 함량 증가율은 12주령군 보다 5주령군에서 높게 나타났다. 간 alcohol dehydrogenase 활성치도 대조군에 있어서는 5주령군이 12주령 보다 약 35% 정도 낮게 나타났으나 xylene 투여로 인한 본 효소의 활성 증가율은 5주령군에서 오히려 높게 나타났다. 그러나 간 aldehyde dehydrogenase 활성치는 대조군 및 xylene 투여군 모두 5주령과 12주령간에 유의한 차이를 나타내지 않았다. 한편 xylene 투여시 체중 당 간무게, 간조직 malondialdehyde 함량 및 혈청 ALT 활성 변동을 통하여 간손상 정도를 상호 비교 관찰하였을 때, 12주령군이 5주령 실험동물 보다 간손상이 다소 심하게 나타남을 알 수가 있었다. 이상 실험결과는 연령에 따라 xylene에 의한 간손상의 차이는 이물질의 생체내 대사율이 달리 나타나기 때문일 것으로 생각된다. To evaluate an effect of aging on the xylene toxicity, 50% m-xylene in olive oil (0.25 ml/100 g body wt.) was administered to 5 week and 12 week-old rats one times intraperitoneally and sacrificed at 24 hrs afterwards. The increasing rate of urinary H-methylhippuric acid concentration was higher in 12 week-old rats than 5 week-old rats by the treatment of m-xylene. On the liver function findings, i.e., liver weight/body weight (%), serum levels of ALT activity and hepatic malondialdehyde content, 12 week-old rats showed more severe liver injury than 5 weeks those in xylene-treated rats. And the hepatic cytochrome P-450 contents was higher in 12 weeks rats than those of in 5 week-old rats, but the increasing rate of that was lower in 12 week-old rats. Hepatic alcohol dehydrogenase activity was also higher in 12 week-old rats than in 5 week-old rats whereas the increasing rate of that was higher in 5 week-old than those in 12 week-old rats by the xylene treatment. Furthermore, the hepatic aldehyde dehydrogenase activities were no differences between the 5 and 12 week-old rats both in the control and xylene-treated group, In conclusion, age may influences upon the hepatotoxicity with xylene and it may be responsible for xylene metabolism in rats.

방사선적 물리적 특성에 의한 담석의 성분 분석

함희원,성무경,전혜정,선관우 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

In this study, gall stones from 45 patients were analyzed in vitro. Gall stones from 23 patients were cholesterol stones and the others were non-cholesterol. Correlation with each radiologic physical properties(the number of stones, shape, calcification pattern, Hounsfield units measured by computed tomography) and chemical composition(cholesterol or non-cholesterol) were analyzed. The results revealed that the numbers and size were not related to the chemical composition, but there were significant correlation with faceted stones(p=0.002) or stones with no calcification (p=0.010) and cholesterol composition, and with irregular stones(p=0.000) or stones with dense calcification(p=0.015) and non-cholesterol composition. In study of Hounsfield units, it was difficult to fix the boundary, but the difference between cholesterol composition(138.43±281.81) and non-cholesterol composition(404.32±306.06)was significant(p=0.0109).

한국산 배의 Polyphenol 화합물군이 쥐의 면역기능에 미치는 영향

최희진,한호석,박정혜,배종호,우희섭,안봉전,배만종,김현구,최청 한국식생활문화학회 2003 韓國食生活文化學會誌 Vol.18 No.4

This study was conducted to investigate immunofunctional activity of the polyphenol fractions isolated from Korean pear. In the experimental of Rosette forming cell, the results showed that all the polyphenol fractions enhance the cell count compared with the control group. Especially polyphenol fraction II and III showed highly significant effect on Rosette forming cell, and allergy inhibition. After antigen challenge, histamine content of blood of the polyphenol groups was lowered to near the normal group.

중환자에서 동맥혈 가스분석 횟수와 그로인한 실혈량에 대한 연구

이석열,전철우,정영수,오희숙,마분란,이정미,정혜영,이만복,이길노 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Background : Arterial blood gas analysis is the most comon exam in intensive care unit. In this study, the frequency of blood gas analysis and the amount of blood loss after Blood Gas Analysis in Intensive Care Unit were observed. Methods : From November 1999 to February 2000, 115 patients admitted to intensive care unit at Soonchunhyang university Kumi hospital were studied prospectively for the frequency of blood gas analysis and the amount of blood loss after blood gas analysis in Intensive Care Unit. Results : The mean value of frequency of blood gas analysis was 6.41±6.49 and the mean value of amount of blood loss after blood gas analysis was 0.78ml. This was lower than that of other foreign reports. The patients with ventilator therapy above 24 hours showed higher frequency of blood gas analysis than that of not applied ventilator patients. Pulse oxymetry was applied to all patients and the frequency of blood gas analysis was decreased due to the use of strict pulse oxymetry. Conclusion : Doctors and nurses in intensive care unit keep in mind that adequate blood sampling is needed for the decrease of blood loss. Education and protocol for the decrease of blood loss after arterial blood gas analysis may be necessary.

여대생의 생활습관 및 스트레스가 변비에 미치는 영향

문지희,전혜연,강나영,김희정,배나영,양아롬,왕세미,하주영,이자형 이화여자대학교 간호과학대학 2004 이화간호학회지 Vol.- No.38

The purpose of this research is to analyze relationships among the habitual life, stress, and constipation and to help prevent and improve the constipation among women's university students. This is a descriptive interrelated research that has targeted women's university students. The data had been collected for 10 days, from December 22, 2003 to December 31, 2003. The survey was carried out to the 295 women's university students that had been randomly selected by visiting four-year-course colleges and universities in Seoul. The survey consists of 78 questions: five questions on the general trait, 11 questions on the habitual life, 51 questions on the stress, and 11 questions on the constipation. There are seven questions on the dietary life, four questions on exercising, and Shin Jung Ran's survey(2003) and Lee Ji Jung's survey(2001) was used as a reference. Yoon Ho Yul's five grade stress barometer(1996) was also used to measure the amount of stress. The collected data was analyzed by a real number, percentage, the arithmetical mean, the standard deviation, t-test, x²test using SPSS 10.00 for Windows Program. Results are as follow 1. Four to six cups of daily water intake was the highest by 50.0%. Students not have breakfast(55.7%) mostly because they did not have enough time(62.6%). Dinner was the most overeated meal by 72.3% and the most preferred food was meat by 42.0%. In the questions related to exercising, more than half of the students answered that they hardly do not exercise(58%), work out for less than 30minutes(67.3%), and exercised lightly(75.3%). 2. Students were suffering from stresses due to the personal relations(51.36±14.0426), scholastic achievement and personal direction(24.93±8.3037), financial conditions and family matters(20.28±8.1718) and social circumstances(2.7262). 3. In the defection part, the student's reply that they have more than five times of bowel movement on a weekly basis(48.3%), and that it takes three to five minutes to defecate(41.3%) were the highest. More than half of the students answered that their one time excrement quantity was between 30 grams to 60 grams(72.3%) and that it was normal(68.7%). In a question asking how it feels after the defecation(students were allowed to choose more than one answer), relieved and refreshed was the highest by 66.6%, an uncomfortable followed by 42.8%. 4.4% of the students answered that they suffer from strong abdominal pain during the defecation. The rest of the students answered that they do not have stomachache or that it was normal. The students were classified into the constipation group of 103 people(34.9%) and the normal group of 192 people(65.1%) under the devised definition of this research. 4. Students that live in dormitories and do their own cooking were more likely to have constipation than those that live in private residence or in a lodgins. 5. The research showed that there is a mutual relation between water in a day intake and the constipation. It means that the lesser water students drink, the more they suffer from the constipation. The number of times a student had a meal everyday and the constipation was interrelated. If a student had lesser or irregular meals in a day, they had more constipation. Preferred food and constipation was also interrelated. Students that preferred vegetable, fruit, and dairy products were more likely to belong in a normal/general group. 6. By dividing the stress factors into the lower categories, we were able to see that the total stress(t-2.063, p-0.040), personal relations(t-2.316, p-0.021), scholastic achievements and personal directions(t-20127, p-0.034) had mutual relation with the constipation. The constipation group(120.27±30.2708) was suffering from stronger level of stress than the normal group(112.97±28.1466). Through this study, we were able to verify that the few general traits, habitual life, and stress of the women's university students have mutual relations with the constipation.