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경막 내 colistimethate 투여로 치료한 다제 내성 cinetobacter baumannii 뇌실염
홍유아,유진홍,김진진,모은영,안건희,정희경,김진석,이현정,정미향,윤승배 대한감염학회 2009 감염과 화학요법 Vol.41 No.4
Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.
( Hyang Jin Yoon ),( Hyo Jin An ),( Chung Hyun Kim ),( Yeon Hwa Kim ),( Sung Hwan Wee ),( Jin San Moon ) 한국예방수의학회(구 한국수의공중보건학회) 2015 예방수의학회지 Vol.39 No.3
In this study, we investigated and analyzed the registration, sales and regulatory management system of in vitro diagnostic veterinary medical reagents (IVDVMRs) in Korea. The registration of IVDVMRs has gradually increased since 2000, and total of 233 products from 58 companies were registered from 1975 to 2014. The market size of IVDVMRs is estimated to be approximately 12 billion Won per year from 2011 to 2013: the export sales and proportion was estimated to be 36.8% as 4.4 billion Won in 2013. Of these products, the ranking of the sales were canine heartworm, bovine tuberculosis, swine fever, porcine reproductive and respiratory syndrome, canine distemper+adenovirus+parvovirus disease, foot and mouth disease, etc. In vitro diagnostic human medical reagents were diverted biological medicine from the medical devices by the revision of the Pharmaceutical Affairs Law Enforcement Regulations in 2014 in Korea. In contrast, in vitro diagnostic devices for animal were still managed as medical devices and biological medicines, respectively. The diagnostic reagents for infectious diseases have neither classification nor grade systems. Good manufacturing practices (GMP) requirements on IVDVMRs were also exempted from the current system. This study suggested that the registration of the IVDVMRs has increased since 2005, and regulations of these devices should be improved for the effective operating system.
Jae Yoon Cha,Ae-Jin Choi,Bo-Youn Chun,Min-Ji Kim,Hyang Sook Chun,Chul-Jin Kim,Yong-Jin Cho,Chong-Tai Kim 한국식품과학회 2007 Food Science and Biotechnology Vol.16 No.6
The acid modification of waxy rice starch was conducted to improve the yugwa production process. The intrinsic viscosity, paste viscosity, and differential scanning calorimetry characteristics of acid modified starch were measured, and bandaegi and yugwa prepared from acid modified starch were evaluated. The intrinsic viscosities of acid thinned starches were 1.48, 1.27, 1.15, and 0.91 mL/g after reaction times of 1, 2, 3, and 4 hr, respectively. The gelatinization enthalpy was reduced from 16.3 J/g in native starch to 15.8, 15.3, 14.7, and 14.5 J/g in acid thinned starches as the time of acid thinning increased. The peak viscosity and final viscosity decreased with increasing the time of acid thinning, but the pasting temperature was slightly increased in acid thinned starches. The hardness of bandaegi from acid thinned starches under high pressure greatly decreased relative to the control, typical yugwa. Yugwa from acid thinned starch under high pressure maintained a homogeneous structure containing tiny and uniform cells similar to that of native waxy rice starch used for typical yugwa. Acid thinning under high pressure appears to be a good alternative to the existing steeping process for better yugwa quality.
류마티스 다발근육통증 환자의 전형적 18-FDG-PET/CT 소견 1예
박진수 ( Jin Su Park ),표정윤 ( Jung Yoon Pyo ),박희진 ( Hee Jin Park ),이향선 ( Hyang Sun Lee ),강윤 ( Yoon Kang ),강미일 ( Mi Il Kang ),송정식 ( Jung Sik Song ),박용범 ( Yong Beom Park ),이수곤 ( Soo Kon Lee ),이상원 ( Sang Won 대한류마티스학회 2013 대한류마티스학회지 Vol.20 No.2
PMR의 병태생리는 명확히 밝혀져 있지 않지만, 염증을 시사하는 병리학적 소견이나 ESR의 상승은 염증이 주된 병인기전임을 시사한다. 최근 PMR 환자에서 시행한 18-FDG-PET에서 윤활막염과 윤활낭염 및 혈관염 등의 특징적인 소견이 관찰되고 있다. 이 증례는 PMR 환자에서 18-FDG-PET/CT를 시행하였고, 전형적인 윤활막염, 윤활낭염, 무증상의 큰 혈관염 등이 관찰된 첫 번째 증례이다. 향후 한국인 PMR 환자의 진단시, 18-FDG-PET의 유용성에 대한 정확한 자료를 얻기 위해서 표준화된 방법을 통한 여러 환자에서의 시행이 필요할 것이다. Polymyalgia rheumatica (PMR) is an inflammatory rheumatic condition characterized by generalized pain and morning stiffness in the shoulders, hip girdle, and neck. Since the pathogenesis of PMR is still uncertain, the diagnosis of PMR depends on clinical features. There have been several studies regarding radiological tools for the diagnosis of PMR. Recent studies using 18-FDG-PET showed bursitis, synovitis, uptake in the spinous process and asymptomatic large-vessel vasculitis in PMR patients. However, there was no report on the efficacy of 18-FDG-PET for diagnosis of PMR in Korea. Here, we are first reporting a case of a Korean patient with PMR, who had radiological findings including bursitis, synovitis, uptake in the spinous process and asymptomatic large-vessel vasculitis on 18-FDG-PET/CT.
Anaphylactic shock following intravenous ranitidine in pregnancy woman
( Yoon Hyeon Hu ),( Tae Yeon Kim ),( Tae Gyu Ahn ),( Hyang Ah Lee ),( Jong Yun Hwang ),( Dong Hun Lee ),( Se Jin Lee ),( Sunghun Na ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-
Ranitidine is generally safe in pregnancy. Anaphylaxis is rarely observed with ranitidine. Anaphylaxis is triggering maternal hypotension leading to intrapartum hypoxic-ischemic encephalopathy in the infant. Furthermore, cesarean sections are performed at a high rate of anaphylactic pregnant woman. A 43-year-old primigravida was hospitalized for a cesarean section at 38+3 weeks of gestation. She didn’t have any underlying disease. She had histories of drug allergy for common cold medication. But she didn’t know exactly what drugs were causing allergies. Following admission, before the cesarean section, ranitidine was injected to her. At the beginning of the injection, the patient complained of dizziness, and within seconds she experienced shortness of breath and chest tightness. Several minutes later she experienced dyspnea, sweating, and severe cramping pain in the abdomen. Further, the fetal heart revealed bradycardia (70-80 beats per minute). She has received an emergency cesarean section under general anesthesia. A male infant weighing 3220 g was delivered with Apgar scores of 2 and 3 and 4 at 1, 5 and 10 minutes. The infant was transferred to the neonatal intensive care unit. After the surgery, the mother was received routine post-operation care and discharged home. We report a case who developed severe anaphylaxis following a single dose of intravenous ranitidine in the rare case.
A comparison of ankle function between adults with and without Down syndrome
Yoon, Hyang-Woon,Yu, Tae-Ho,Seo, U-Hyeok,Lee, Jee-Won,Kim, So-Yeon,Chung, Soo-Jin,Chun, Hye-Lim,Lee, Byoung-Hee korean Academy of Physical Therapy Rehabilitation 2017 Physical therapy rehabilitation science Vol.6 No.4
Objective: The purpose of this study was to compare ankle function between adults with and without Down syndrome (DS). Design: Cross-sectional study. Methods: Ten adults with DS and 18 without participated in this study and underwent manual muscle test (MMT), range of motion (ROM) assessment, star excursion balance test (SEBT), and functional movement screen (FMS). The tests were demonstrated to increase their accuracy and the actual measurements were assessed after one or two demonstrations. To minimize the standby time and fatigue, the travelled distance and measuring order were adjusted. To remove the influence of shoes on the measurements, the shoes were taken off and only socks were worn. Results: Dorsal and plantar flexion MMTs of both ankles were significantly weaker and plantar flexion ROM of both ankles were significantly lower in adults with DS compared with those without (p<0.05). However, dorsal flexion ROM of both ankles were not significantly different between them. There were significant differences in distances measured in all the directions (anterior, anterolateral, lateral, posterolateral, posterior, posteromedial, medial, and anteromedial directions) of SEBT (p<0.05). Significant differences were also demonstrated in the scores of hurdle step, inline lunge, shoulder mobility, and rotary stability among the seven items of FMS (p<0.05). Conclusions: To enhance the dynamic stability of adults with DS, it is necessary to improve ankle stability by strengthening the ankle dorsal and plantar flexors.
Pancytopenia in pregnancy woman with upper respiratory infection
( Yoon Hyeon Hu ),( Tae Yeon Kim ),( Tae Gyu Ahn ),( Hyang Ah Lee ),( Sunghun Na ),( Jong Yun Hwang ),( Dong Hun Lee ),( Se Jin Lee ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-
Pancytopenia is reductions in all the three major cellular components of blood, and it is the simultaneous presence of anemia, leukopenia, and thrombocytopenia. It complicating pregnancy is rare. But during pregnancy it could be life-threatening for both mother and child. Pancytopenia, which occurs early in pregnancy, is particularly challenging in clinical settings because pregnancy management and outcomes are entirely dependent on underlying causes. The assessment of patients with pancytopenia requires a comprehensive approach and it can be difficult to determine the root cause when considering various causes, including drugs, autoimmune conditions, malignancies, infections, hemophagia, and inheritable conditions. While bone marrow failure syndromes and malignancies are important causes, certain non-malignant conditions such as infection and nutritional anemia are equally important causes. We present a 29-year primigravida woman with an uneventful medical history who was referred at 17weeks gestational age as a case of fever with pancytopenia. She had a cough and sore throat. And serum C-reactive protein and procalcitonin levels were elevated. She was admitted, investigated and diagnosed as a case of pancytopenia with peripheral blood smear showing normocytic normochromic anemia with aniso-poikilocytosis, leukopenia with lymphopenia (10%190/uL), and moderate thrombocytopenia. She was treated intravenous antibiotics and after the infection has been cured, the pancytopenia has improved spontaneously after 3 weeks later. We report a case who developed pancytopenia following upper respiratory infection in the rare case.