고요산혈증의 위험인자 : 아산시 지역 주민을 대상으로

김용배,장원기,황보영,김화성,안규동,이병국,이용진,이종은,이준숙,이찬구,이한정,이성수 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

Objective : Serum uric acid has now been identified as a marker for a number of metabolic and hemodynamic abnormalities. The aim of this study is to evaluate risk factors which influence hyperuricemia in the citizens of Asan. Method : The study design was cross-sectional and research subjects were 1086 citizens of Asan. General characteristics, cigarette smoking, alcohol consumption, and past history were obtained by interview using a structural questionnaire. Also, we measured height, weight and blood pressure, and serum uric acid of the subjects. Results : The mean serum uric acid level was 5.27 ㎎/㎗ in men and 4.01 ㎎/㎗, in women, In the multiple logistic regression analysis, statically significant risk factors of hyperuhcemia were gender, body mass index, blood lead concentration, and serum creatinine. Conclusion : Our results suggest that gender, body mass index, blood lead concentration, and serum creatinine might be the most important risk factors of hyperurcemia. Education program as well as routine check-up for serum uric acid was highly recommended for the effective prevention of hyperuricemia.

DAP 신념에 근거한 유아과학 교수·학습모형의 현장적용 효과

이정화,이미은 미래유아교육학회 2003 미래유아교육학회지 Vol.10 No.4

DAP(Developmentally Appropriate Practice)는 유아교육실제의 질을 진단ㆍ평가하는 타당한 기준으로 인정받고 있을 뿐 아니라 유아교육과정의 설계나 프로그램 개발에 고려해야 할 준거로 널리 활용되고 있다. 본 연구는 DAP 신법에 근거하여 만들어진 절차화된 유아과학 교수ㆍ학습모형(이정화, 2002)을 유아교육 현장에 적용하여 그 효과를 검증해 보고자 하였다. 이를 위해 연구자들은 두 가지 교수학습방법(DAP 신념에 근거한 유아과학 수업모형과 전통적 수업모형)을 적용한 과학활동 프로그램을 구성, 처치한 후 유아들의 과학적 호기심 및 과학적 과정 기능의 향상 정도를 살펴보았다. 연구결과 DAP 신념에 근거한 절차화된 유아과학 교수ㆍ학습모형에 의한 과학활동 프로그램에 참여한 유아들이 전통적 교수법에 의한 과학활동 프로그램에 참여한 유아들보다 유의하게 높은 향상을 보였음이 확인되었다. The purpose of this study was to examine the effects of a developmently appropriate model of teaching science(DAP model) which is developed by Lee Jeong-Hwa(2002) on children’s curiosity and scientific process skills. Two research questions were made from the review of the literature, as follows ; 1. Are there any differences in science curiosity between children in an experimental and a control group? 2. Are there any differences in science process skills between children in an experimental and a control group? To answer the questions, forty five-year-old children attending a preschool in Busan participated in this study. They were randomly assigned to either an experimental or a control group. Children in the experimental group, took part in eight 40~45 minute sessions of science program based on the DAP model; whereas, their counterparts in the same sessions of a traditional science program. After the sessions of each program, all children were tested on the science processing skill test and the science curiosity test. The children who took the DAP model received higher achievement than their counterparts on curiosity and scientific process skills. From the results, the researchers suggest to apply the DAP model of teaching science for young children in the education field.

1995-96년 한반도 남동부 지역의 미소지진 자료를 이용한 지각구조 모델의 비교 연구

이기화,정태웅,Lee, Gi Hwa,Jeong, Tae Ung 한국지구물리물리탐사학회 1999 지구물리 Vol.2 No.1

한국자원연구소 지진관측망의 1995-96년 미소지진 자료를 바탕으로 한반도 남동지역의 지각구조에 대하여, Lee (1979), 김상조·김소구(1983), 김성균·정부흥(1985)의 세 지각 모델 중 어느 것이 잔차의 최소자승을 만족하는지 검증하였다. 세 모델 잔차의 뚜렷한 차이가 관찰되지 않았으나, Lee 의 지각 모델이 약간 깊은 진원을 산출하는 경향이 있다. 한반도 지각의 층상구조는 아직 명백하지 않으므로 앞으로 더 많은 자연지진 자료 또는 인공지진 자료를 통해서 규명되어져야 한다. Using the microearthquake data acquired from 1995 to 1996 through the seismic network operated by the Korea Institute of Geology, Mining & Materials (KIGAM), the three P-wave velocity models proposed by Lee (1979), Kim·Kim (1983) and Kim·Jung (1985) concerning the structure of the southeastern part of the Korean peninsula were examined in terms of the least square errors of the P-wave arrival times. The three models do not differ significantly in arrival time residuals except that the Lee's model gives slightly deeper focuses than the others. The layering of the crust of the peninsula is not clear as yet and to be studied by more earthquake and explosion data in the future.

Plant regeneration from callus of Iris odaesanensis Y. N. Lee native to Korea via organogenesis

Bae, Kee-Hwa,Yoo, Kyoung-Hwa,Lee, Mi-Hyun,Jeong, Jae-Hun,Choi, Yong-Eui,Yoon, Eui-Soo The Korean Society of Plant Biotechnology 2013 식물생명공학회지 Vol.40 No.3

Iris odaesanensis Y. N. Lee. is an important endangered and native plant belonging to the family Iridaceae in Korea. This study describes a method for rapid micropropagation of this species via from leaf, rhizome and root explants derived calli. Leaf, rhizome and root explants were cultured on Murashige and Skoog (MS) medium supplemented with 2,4-dichlorophenoxy acetic acid (2,4-D) for callus induction. Rhizome explants yielded calli at a frequency of 72% when cultured at 1.0 mg/l 2,4-D. Calli were maintained at 1.0 mg/l 2,4-D. These calli were transferred to MS medium supplemented with 0, 0.5, 1.0, and 2.0 mg/l 2,4-D in combination with 0, 0.5, 1.0, and 3.0 mg/l BA for adventitious shoot induction. The highest number of adventitious shoot (228.9 per petri-dish) were formed at 1.0 mg/l 2,4-D and 1.0 mg/l BA. WPM medium was the best to convert calli into plantlets, where up to 98.2% of calli were regenerated into plantlets. This in vitro propagation protocol should be useful for conservation of this endangered plant.

화병(火病)을 동반한 갱년기 환자 치험 5례

송유림 ( Yu-rim Song ),박경미 ( Kyung-mi Park ),양승정 ( Seung-jeong Yang ),이은규 ( Eun-kyu Lee ),김혜화 ( Hye-hwa Kim ),조성희 ( Seong-hee Cho ) 대한한방부인과학회 2016 大韓韓方婦人科學會誌 Vol.29 No.4

Objectives: The purpose of this study is to evaluate the effects of Korean traditional treatments for Climacteric Syndrome Patients with Hwa-Byung. Methods: From February 2015 to May 2015, We treated 5 Cases Patients with Korean traditional treatments for a month. We measured treatment effects by Menopause Rating Scale (MRS), Beck`s Depression Inventory (BDI), Visual Analogue Scale (VAS) and Digital Infrared Thermal Imaging (DITI). Results: After treatment, First, the scores of MRS, BDI were decreased. Second, the symptoms such as hot flush, pantalgia, palpitation, insomnia, fatigue were significantly improved. Also, the difference of ?中 (CV17, Danjung) and 關元 (CV4, Guanyuan) temperatures were significantly decreased after treatment. Conclusions: This study suggests that Korean traditional treatments such as Gamicheonglijagam-hwan, acupuncture, moxibustion are effective on Climacteric Syndrome Patients with Hwa-Byung.

청간소요산으로 호전된 설통 환자 3례

김연진,양승보,김정화,이상화,조승연,박성욱,박정미,고창남,Kim, Yeon-jin,Yang, Seung-bo,Kim, Jeong-hwa,Lee, Sang-hwa,Cho, Seung-yeon,Park, Seong-uk,Park, Jung-mi,Ko, Chang-nam 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.4

Objectives: This clinical study reports the effects of Cheonggansoyo-san (CSS) on three patients with glossodynia. Methods: Three patients with glossodynia were treated with CSS (i.e., an herbal medicine) and acupuncture. Numeric rating scales (NRSs) for glossodynia and dry mouth and hwa-byung questionnaire scores were evaluated, and the results from heart rate variability (HRV) evaluations were analyzed. Results: After treatment with CSS, three patients' glossodynia symptoms, such as burning sensations, tingling, and numbness of the tongue, were improved. NRS ratings for glossodynia and dry mouth and the hwa-byung questionnaire scores also improved, and HRV parameters were closer to the normal range. Conclusion: Cheonggansoyo-san could be used to treat glossodynia.

中空 坐劑의 약물방출(Ⅰ) : Witepsol H-15 기제로부터의 인도메타신의 방출속도 Release Rate of Indomethacin from Witepsol H-15 Suppository

이화정,구영순 梨花女子大學校 藥學硏究所 1991 藥學硏究論文集 Vol.- No.1

In order to study drug release from the suppository, three types of hollow suppositories and one conventional suppository were prepared using indomethacin (IDM) as a model drug and Witepsol H-15 as a base. The 4 types of suppository prepared are as follows : typeⅠ, conventional suppository containing 50mg of IDM powder, typeⅡ, hollow suppository containing 50mg of IDM powder in the cavity, typeⅢ, hollow suppository containing 25mg of IDM powder in the base and IDM microcapsules (25mg as IDM powder) in the cavity, and type Ⅳ, hollow suppository containing IDM microcapsules (25mg as IDM powder) in the base ans 0.5ml of 5%(w/v) IDM-PEG 300 solution in the cavity. The drug amount released(%) from typeⅡ and Ⅰ within 24hrs was 46.7% and 66.9%, respectively. Comparing with the drug amount released from four types of suppository within initial 2hrs and 24hrs, that of type Ⅳ was high as 32.7% and 76.6%, respectively. IDM-ethycellulose microcapsules passed through 270 mesh sieve and the IDM content was 20.95%.

鶴峯의 樓亭詩 硏究

이정화 慶北大學校 退溪硏究所 2004 退溪學과 韓國文化 Vol.- No.34

누정시는 景物詩 가운데서도 핵심을 이루는 부분이다. 퇴계학맥을 창도한 퇴계의 경우, 實景을 묘사하는 敍景은 하지 않고, 대상의 내재적 의미를 확인하거나 드러낸 시편이 많다. 퇴계의 嫡傳인 학본의 누정시에서 寫景의 비중이 크지 않은 것은 그가 바로 스승 퇴계와 같은 도학적 시인임을 입증하는 것이 되며, 이것이 학본의 누정시와 퇴계의 그것에서 보여지는 공통된 특징이라 하겠다. 특히, 학봉은 스승 퇴계가 시를 남겼던 누정에 올랐을 때의 감회를 읊은 次韻詩를 제작하였다. 또한, 학봉의 누정시에서는 公人意識과 치열한 현실인식을 바탕으로 하여, 亂世를 잘 극복해보려는 지식인의 鬪志를 담아내기도 하는 등 독자적인 시세계를 구축하고 있다. 그의 公平無私한 삶의 片鱗은 宦路에서 제작된 누정시에서 찾아지는데, 「矗石樓一絶」을 제작하는 순간에 公人意識이 가장 절정에 이르렀음을 알 수 있다. 42세 때에 함경도 巡撫御史로 있으며 제작한 「登惠山鎭掛弓亭」, 「鎭戎樓」에서, 학봉의 정신은 지난날 이 지역에서 호령하였던 尹瓘, 金宗瑞 장군의 기개를 닮고 있다. 시 속에 투영된 그의 義血은 愛民意識과 관련된 것이다. 왜나하면, 그가 수자리하는 병사들의 지친 모습을 놓치지 않고 있기 때문이다. 「定平府次軒韻」에서는 국가를 위해 한 목숨을 기꺼이 바친다는 一念이 邊方의 오랑캐를 향한 殺伐한 기상으로 표출되고 있다. 이로써 보면, 학봉은 퇴계의 누정시에서 확인된 도학적 서정시의 경계를 창조적으로 계승하였다고 하겠다. 그의 시에는 스승을 닮으려는 溫柔敦厚한 資稟과 칼을 찬 선비의 굳센 기상이 공존하고 있다는 점에서 이러한 사실을 확인할 수 있다. This paper aims to investigate Hak-bong poetry considering a scholar-official poet of 16C in Joseon. Generally he was a accomplished scholar as study of human nature(性理學). This paper is an attempt to illustrate the poetic spirit of Hak-bong. To achieve this purpose, this paper starts from the view of life. We can find the fact that his personality is based on the practical knowledge of Toegye. The arbor poetry of Toegye reveals a remark full of meaning. having no concern with poetical title. Hak-bong were inclined to approach him from the Cha Woon of Toegye poetry. The arbor poetry of Hak-bong embody the truth of life and exhibit the sympathy of the poor His poetry expresses his poetical words suggest that he reveals the recognition of reality.

쐐기형 5급 와동과 근관와동을 복합레진으로 수복한 상악소구치에 대한 응력 분석 : 3차원 유한요소법적 연구

이선화,김현철,허복,김광훈,손권,박정길 大韓齒科保存學會 2008 Restorative Dentistry & Endodontics Vol.33 No.6

이 연구의 목적은 쐐기형 5급 와동과 근관와동을 복합레진으로 수복한 상악 제2소구치에 대한 응력 분포를 3차원 유한요소법으로 분석하여 평가하기 위한 것이다. 발치된 상악 제2소구치를 이용하여 Micro-CT로 스캔한 후 3D-D0C-TOR로 3차원 유한요소 모형을 제작하였다. 제작된 소구치 모형에 근관 와동을 형성하고 쐐기형 5급 와동과 글래스 아이오노머 기저재의 사용 여부를 구분하여 근관 와동을 혼합형 복합레진으로 충전하였다. 협측 교두 또는 설측 교두에 500 N의 하중을 가하고, ANSYS 8.0 프로그램으로 인장 응력의 분포를 분석하여 평가한 결과 베이스 사용유무에 따른 응력 분포의 차이는 없었다. 협측 교두에 하중이 가해질 때, 하중점과 교합면의 중심구, 구개측 백악법랑경계부에 과도한 인장 응력이 집중되었으며, 5급 와동이 없는 경우보다 5급 와동이 있는 경우에 약간 더 높았다. 설측 교두의 협측 경사면에 하중이 가해질 때, 하중점과 교합면의 중심구, 협측 치경부에 과도한 인장 응력이 집중되었으며, 5급 와동이 있는 경우가 5급 와동이 없는 경우보다 약간 더 낮았다. The purpose of this study was to investigate the distribution of tensile stress of canal obturated maxillary second premolar with access cavity and notch-shaped class Ⅴ cavity restored with composite resin using a 3D finite element analysis. The tested groups were classified as 8 situations by only access cavity or access cavity with notch-shaped class Ⅴ cavity (S or N), loading condition (L1 or L2), and with or without glass ionomer cement base (R1 or R2). A static load of 500 N was applied at buccal and palatal cusps. Notch-shaped cavity and access cavity were filled microhybrid composite resin (Z100) with or without GIC base (Fuji Ⅱ LC). The tensile stresses presented in the buccal cervical area, palatal cervical area and occlusal surface were analyzed using ANSYS. Tensile stress distributions were similar regardless of base. When the load was applied on the buccal cusp, excessive high tensile stress was concentrated around the loading point and along the central groove of occlusal surface. The tensile stress values of the tooth with class Ⅴ cavity were slightly higher than that of the tooth without class Ⅴ cavity. When the load was applied the palatal cusp, excessive" high tensile stress was concentrated around the loading point and along the central groove of occlusal surface. The ten-sile stress values of the tooth without class Ⅴ cavity were slightly higher than that of the tooth with class Ⅴ cavity.

한국인에서 도파민 D4 수용체 다형성과 Novelty Seeking 성격 특성의 연관성

이헌정,이홍석,강화연,김린,이민수,서광윤,변영찬 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.4

연구목적 : 저자들은 한국인에서 도파민 D4 수용체(DRD4) 유전자의 다형성과 성격의 관련성을 알아보고자 본 연구를 시행하였다. 방 법 : 173명의 건강한 한국인 여자 청소년(13.88±0.29세)을 대상으로 하여 성격 기질 설문지(Temperament and Character Inventory : TCI)를 작성하도록 하였으며, 이들에서 DRD4 exon Ⅲ 48-bp VNTR(variable numbers of tandem repeats) 다형성을 분석하였다. 결 과 : DRD4 exon Ⅲ Vntr에서 긴 대립유전자(≥5 repeats)를 가진 군이 긴 대립유전자를 가지지 않은군에 비하여 Novelty Seeking 척도 점수가 유의하게 높았다(t=2.11,p=0.037). 결 론 : 본 연구 결과는 DRD4-exon Ⅲ의 긴 대립유전자가 Novelty Seeking 성격과 관련이 있다는 기존의 외국에서의 연구결과를 다시금 확인해주는 것이다. Objectives : We investigated the relationship of personality traits with dopamine D4 receptor(DRD4) exon Ⅲ polymorphism in a Korean population. Methods : We analysed DRD4 exon Ⅲ 48-bp repeats polymorphism in 173 Korean heakthy female adolescents(age=13.88±0.29years) who also completed Temperament and Charater Inventory(TCI). Results : Novelty seeking score of the TCI was significantly higher in the subjects with DRD4 long alleles(≥5 repeats) compares with the subjects without these (t=2.11, p=0.037). Conclusion : The present study supports the previous reports that long repeats of the DRD4-exon Ⅲ polymorphism are relatedwith Novelty Seeking personality.