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유택규,박상규,김미영,유은희,강병조 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.2
This study was performed to identify personality trait of patients with methamphetamine and alcohol abuse by analyzing MMPI profiles. 93 methamphetamine abuse patients, 59 alcohol abuse patients and 52 healthy subjects completed MMPI. Each MMPI profile in three groups was analyzed by F-test and discriminant function analysis. Alcohol abuse patients showed higher scores n F, Sc(8), and Si(0) profiles of MMPI than the patients with methamphetamine abuse. 3 variables(F, Si, Pd) were discriminated in there two groups. Methamphetamine abuse patients showed higher cores in F. K. Hs(1), Hy(3), Pd(4), Pa(6), Sc(8), and Ma(9) profiles of MMPI than the normal controls. 5 variables (Pa, Pd, Si, K, L) were well discriminated in these two groups. The alcohol abuse patients showed higher scores in F, Hs(1), D(2), Hy(3), Pd(4), Mf(5), Pa(6), Pt(7), Sc(8), and Ma(9) profiles of MMPI than the normal controls, but lower scores in K subscale, 3 variables(F, Pb, Pa) were well discriminated in these two groups. Specially these results indicated that alcohol abuse patients had more psychotic symptoms than methamphetamine abuse patients. These results may suggest that addicted individuals have personality traits to be drug addicts, but it was unclear that these results were ue to predisposing personality traits or results of drug abuse.
Kim, Gyoo-mi,Lee, Sang-jun The Korea Contents Association 2016 International Journal of Contents Vol.12 No.3
The purpose of this study was to examine how Korean students accept and use mobile-assisted language learning (MALL) and investigate related factors that potentially affect MALL usage. The participants were 244 undergraduate students who were surveyed with a questionnaire. The research model, which included students' self-efficacy, content reliability, interactivity, perceived enjoyment, perceived usefulness, perceived ease of use, attitude, and behavioral intention to use MALL, was developed based on the technology acceptance model (TAM). The structural equation modeling (SEM) technique was employed in order to analyze the overall results of modified TAM and the research model. The results indicated that TAM was a good theoretical tool to understand students' acceptance of MALL. In addition, all constructs, with the exception of self-efficacy and interactivity, had significant effects on students' acceptance possibilities of MALL. Limitations and suggestions for the further study are also presented.
Establishment of Validation Methods to Test the Biocompatibility of Titanium Dioxide
Kim, Mi-Ju,Lim, Hee-Joung,Lee, Byung Gun,Kim, Jong-Hoon,Choi, Jinsub,Kang, Hee-Gyoo Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.6
Most of biomaterials come in direct contact with the body, making standardized methods of evaluation and validation of biocompatibility an important aspect to biomaterial development. However, biomaterial validation guidelines have not been fully established, until now. This study was to compare the in vitro behavior of osteoblasts cultured on nanomaterial $TiO_2$ surfaces to osteoblast behavior on culture plates. Comparisons were also made to cells grown in conditioned media (CM) that creates an environment similar to the in vivo environment. Comparisons were made between the different growth conditions for osteoblast adhesion, proliferation, differentiation, and functionality. We found that the in vivo-like system of growing cells in concentrated CM provided a good validation method for biomaterial development and in vivo implant therapy. The $TiO_2$ materials were biocompatible, showing similar behavior to that observed in vivo. This study provided valuable information that would aid in the creation of guidelines into standardization and evaluation of biocompatibility in $TiO_2$ biomaterials.
A Hierarchical Evaluation for Success Factors of the Mobile-Assisted Language Learning Using AHP
Kim, Gyoo-mi,Lee, Sang-jun The Korea Contents Association 2017 International Journal of Contents Vol.13 No.3
With tremendous advancement of information and communication technologies, mobile learning systems have been widely adopted in language learning contexts, and several frameworks have been developed for identifying and categorizing different factors of mobile-assisted language learning (MALL). However, pre-existing frameworks have limitations when evaluating the importance level of criteria. The purpose of this study is to develop a comprehensive hierarchical framework for identifying and categorizing success factors of MALL and prioritizing them according to the importance level. To do that, AHP method is used to quantitatively estimate weight values of MALL criteria. Results reveal that the priority of MALL criteria is ordered as follows: content, system, learner, language learning. Local weights of each criterion are also analyzed; for example, usefulness, accuracy, and authenticity are critical factors for improving MALL contents. Ease of use and mobility of MALL systems are also considered more critical than other systematic factors. In addition, availability of immediate feedback and self-directness has the highest weight values of importance. The findings of the study are discussed regarding hierarchical orders of MALL criteria and conclude that successful MALL implementation may be achieved if related elements are diversely measured and evaluated. Pedagogical implications and suggestions for further research are also presented.
Breeding of biparental sex-limited larval marking yellow cocoon variety "Hanbyeolnue"
Kim, Kee-young,Seo, Sang-deog,Kim, Mi-ja,Ji, Sang-duk,Sung, Gyoo-byung,Kim, Yong-soon,Ju, Wan-taek,Kwon, Hae-yong,Sohn, Bong-hee,Kang, Pil-don Korean Society of Sericultural Science 2016 International Journal of Industrial Entomology Vol.32 No.2
All of silkworm varieties reared in farmhouses are first generation hybrids, for the production of these hybrid silkworms precise and labor-saving sex discrimination is necessary. The new variety "Hanbyeolnue" is biparental sex-limited larval marking yellow cocoon variety which was bred from biparental sex-limited strain of Japanese originated Jam 319 and Chinese originated Jam 320. Productivity test of Hanbyeolnue in 2015 showed high healthiness and short larval period. The Hanbyeolnue was evaluated as an excellent variety which can be utilized for special purpose silkworm such as male pupae or Cordyceps production.
Microsatellite Analysis of the Silkworm Strains (Bombyx mori) Originated from China
Kim, Kee-Young,Kang, Pil-Don,Ryu, Kang-Sun,Kim, Ki-Hwan,Sung, Gyoo-Byung,Ji, Sang-Deok,Kim, Mi-Ja,Kim, Ik-Soo Korean Society of Sericultural Science 2012 International Journal of Industrial Entomology Vol.25 No.1
A total of 85 Chinese-origin silkworm strains preserved in Korea were genotyped for eight polymorphic micro-satellite loci. We obtained per-locus number of alleles, ranging from 5 to 14 with an average value of 9.5, perlocus observed heterozygosity, ranging from 0.07 to 0.99, and per-locus polymorphic information content (PIC), ranging from 0.34 to 0.82, indicating that some loci are highly variable. Phylogenetic analysis with the eight concatenated microsatellite loci showed no clustering on the basis of known strain characteristics. A total of 22 strain-specific apomorphic alleles, which discriminate 19 among 85 silkworm strains were obtained from eight loci. These strain-specific alleles, thus, can casually be utilized for the discrimination of applicable strains without any further typing of other loci. Furthermore, a substantial number of homozygote strains, represented by 27 among 76 alleles in eight loci were found. These results collectively suggest that the silkworm microsatellite DNA is actually and potentially important molecular markers for the eventual discrimination of silkworm strains that are preserved as hundreds in Korea.
Kim, Young-Il,Kim, Mi-Jung,Park, Sook Ryun,Kim, Hark Kyun,Cho, Soo-Jeong,Lee, Jong Yeul,Kim, Chan Gyoo,Kim, Gwang Ha,Park, Moo In,Nam, Byung-Ho,Park, Young Iee,Choi, Il Ju The Korean Gastric Cancer Association 2017 Journal of gastric cancer Vol.17 No.2
Purpose: Tumor bleeding is a major complication in inoperable gastric cancer. The study aim was to investigate the effects of proton pump inhibitor (PPI) treatment for the prevention of gastric tumor bleeding. Materials and Methods: This study was a prospective double-blind, randomized, placebo-controlled trial. Patients with inoperable gastric cancer were randomly assigned to receive oral lansoprazole (30 mg) or placebo daily. The primary endpoint was the occurrence of tumor bleeding, and the secondary endpoints were transfusion requirement and overall survival (OS). Results: This study initially planned to enroll 394 patients, but prematurely ended due to low recruitment rate. Overall, 127 patients were included in the analyses: 64 in the lansoprazole group and 63 in the placebo group. During the median follow-up of 6.4 months, tumor bleeding rates were 7.8% and 9.5%, in the lansoprazole and placebo groups, respectively, with the cumulative bleeding incidence not statistically different between the groups (P=0.515, Gray's test). However, during the initial 4 months, 4 placebo-treated patients developed tumor bleeding, whereas there were no bleeding events in the lansoprazole-treated patients (P=0.041, Gray's test). There was no difference in the proportion of patients who required transfusion between the groups. The OS between the lansoprazole (11.7 months) and the placebo (11.0 months) groups was not statistically different (P=0.610). Study drug-related serious adverse event or bleeding-related death did not occur. Conclusions: Treating patients with inoperable gastric cancer with lansoprazole did not significantly reduce the incidence of tumor bleeding. However, further studies are needed to evaluate whether lansoprazole can prevent tumor bleeding during earlier phases of chemotherapy (ClinicalTrial.gov, identifier No. NCT02150447).