Comparison of trophic factors changes in the hippocampal CA1 region between the young and adult gerbil induced by transient cerebral ischemia.

Yan, Bing Chun,Park, Joon Ha,Kim, Sung Koo,Choi, Jung Hoon,Lee, Choong Hyun,Yoo, Ki-Yeon,Kwon, Young-Geun,Kim, Young-Myeong,Kim, Jong-Dai,Won, Moo-Ho Kluwer Academic/Plenum Publishers 2012 Cellular and molecular neurobiology Vol.32 No.8

<P>In the present study, we investigated neuronal death/damage in the gerbil hippocampal CA1 region (CA1) and compared changes in some trophic factors, such as brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF) and vascular endothelial growth factor (VEGF), in the CA1 between the adult and young gerbils after 5 min of transient cerebral ischemia. Most of pyramidal neurons (89%) were damaged 4 days after ischemia-reperfusion (I-R) in the adult; however, in the young, about 59% of pyramidal neurons were damaged 7 days after I-R. The immunoreactivity and levels of BDNF and VEGF, not GDNF, in the CA1 of the normal young were lower than those in the normal adult. Four days after I-R in the adult group, the immunoreactivity and levels of BDNF and VEGF were distinctively decreased, and the immunoreactivity and level of GDNF were increased. However, in the young group, all of their immunoreactivities and levels were much higher than those in the normal young group. From 7 days after I-R, all the immunoreactivities and levels were apparently decreased compared to those of the normal adult and young. In brief, we confirmed our recent finding: more delayed and less neuronal death occurred in the young following I-R, and we newly found that the immunoreactivities of trophic factors, such as BDNF, GDNF, and VEGF, in the stratum pyramidale of the CA1 in the young gerbil were much higher than those in the adult gerbil 4 days after transient cerebral ischemia.</P>

고대산 북서사면(경기도 연천군) 지역의 식물상 및 산림군락 분류에 관한 연구

김남영,김흥식,김영설,김정유,박완근 江原大學校 森林科學硏究所 2004 Journal of Forest Science Vol.20 No.-

2003년 3월부터 10월까지 고대산을 대상으로 식물상과 산림군락을 조사하였다. 관속식물은 94과 299속 481종 1아종 66변종 4품종 1교잡종으로 총 553종류인 것으로 나타났으며, 한국특산식물은 8과 11속 13종 총 13종류, 희귀 및 멸종위기식물은 12과 15속 15속 15종 총 15종류, 귀화식물은 9과 15속 17종 총 17종류로 나타났다. 산림군락은 신갈나무-철쭉군목, 신갈나무-생강나무군단, 갈참나무-신갈나무군락, 굴참나무-신갈나무군락, 당단풍-신갈나무군락으로 전체 1군목, 1군단, 3군락이 분포하는 것으로 나타났다. The study was carried out to investigate the flora and community classification of forest vegetation in Mt. Godae from March to October, 2003. As a result of that, the vascular plants were 94 families, 299 genera, 481 species, 1 subspecies, 66 varieties, 4 formae, 1 hybrid, 553 taxa in all; korean endemic plants were 8 families, 11 genera, 13 species, 13 taxa in all; rare or endangered plants were 12 families, 15 genera, 15 species, 15 taxa in all; naturalized plants were 9 families, 15 genera, 17 species, 17 taxa in all. forest vegetation was classified into 1 order, 1 alliance, 3 communities; Rhododendro - Quercetalia mongolicae (Kim 1990) Lindero - Quercion mongolicae (Kim 1990) A. Fraxinus rhynchophylla - Quercus mongolica Community B. Quercus variabilis - Quercus mongolica Community C. Acer pseudo-sieboldianum - Quercus mongolica Community

벼 생산경영 종합관리 S/W개발

김웅,김창수,김동원,국중덕,송영주,오남기,최영근 한국농업정보과학회 2001 농업정보과학 Vol.3 No.1

This programme consisted of 8 menus, which are basic information, job worksheet, technique information, management analysis, file management, window management, help and conclusion. The major functions of this programme by menus classified as follows : 1. The basic information menu, which consisted of a lots of basic farm management information, can be easily accessible to get general farm status of S/W users and inputted data used as basic data for farm management analysis. 2. In worksheet menu, users can easily access to record and search of farm work planning, contents of work, agricultural materials and selling status. 3. In management achievement menu, lots of indexes which represent one years' management achievements are produced and can be compare this years' achievements with last years' ones. This programme Delphi5 and Object pascal programme were used for tools and languages. Also Paradox4 and BDE were used for DB and DB engine respectively.

방사선 조사에 의한 흰주 난포의 퇴축과 난포세포의 방사선 감수성

김수일,한승로,조근자,허대영,이영호,조문준,김무강,김원식 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

The aim of this study were to investigate radiation-induced atresia and radiation susceptibility in the rat ovary morphologically. Female rats (Sprague Dawley strain) of 4 weeks old were irradiated with dose of 4 Gy and 8 Gy, and sacrificed at hour 6, 12, and 24 after radiation. The H & E stain, the TUNEL method (ApopTag kit) and transmission electron microscopy (TEM) were used. In light microscopic observation, the number of atresia of ovarian follicles were increased significantly at 6h after irradiation (p<0.01). There was no significant difference between 4 Gy and 8 Gy irradiated groups. In TEM observation, granulosa cells in radio-sensitive follicles were characterized by several structural features including condensation of nuclear chromatin granules, nuclear fragmentation and apoptotic body formation. An apoptotic cell is observed to have been phagocytosed by a normal granulosa cell. Granulosa cells in radio-resistant follicles were characterized by several structural features including nuclear indentation, partial condensation of chromatin granules, mitochondrial swelling, dilatation of RER cisterns, accumulation of dense irregular masses, accumulation of lipid droplets, and increased lysosomal bodies. Number of gap junctions between granulosa cells were decreased, and intercellular space were widen than that of control animals. These findings were prominent at 6h after irradiation and were diminished at 12h and 24h after irradiation. With these results, it was concluded that radiation-induced follicular cell apoptosis and ovarian follicular atresia in rat ovary increased considerably at 6h after irradiation. Further studies are needed to reveal the more extensive differences between radiosensitive and radioresistant follicular granulosa cells.

National Security Policies : Reciprocity in South Korean Security Policy Vis-a-vis North Korea and the United States

김영근 ( Young Geun Kim ) 경남대학교 극동문제연구소 2013 ASIAN PERSPECTIVE Vol.37 No.2

I review the principle of reciprocity in South Korean security policy with regard to North Korea and the United States and analyze how the principle fits with US security policy concerning South Korea. Diffuse reciprocity shaped Korean security policy starting with President Kim Dae-jung`s Sunshine Policy. The Lee Myung-bak government`s hard-line approach increased military tension and economic anxiety on the peninsula. The new South Korean government under Park Geun-hye should devise achievable policy measures rather than place excessive pressure or unrealistic demands on North Korea.

딤플을 적용한 평판에 대한 항력 감소 연구

백부근(Bu-Geun Paik),편영식(Young-Sik Pyun),김준형(Jun-Hyung Kim),김경열(Kyung-Youl Kim),김기섭(Kim1 ?Ki-Sup),정철민(Chul-Min Jung),김찬기(Chan-Ki Kim) 대한조선학회 2012 大韓造船學會 論文集 Vol.49 No.4

인삼 선발계통의 지역적응성 검정

Bong Jae Seong,Sun Ick Kim,Ka Soon Lee,Moo Geun Jee,Su Dong Kim,A Reum Kwon,Hyun Ho Kim1,Young Chang Kim 한국약용작물학회 2017 한국약용작물학술대회 발표집 Vol.2017 No.05

Background : For cultivation of varieties of ginseng, the pure line selection method, which is to select the best among those cultivated in farms for pedigree breeding, replicated yield trials and regional adaptation trials before registering as a new variety, is widely used. Although there are 25 registered varieties of ginseng in Korea, the quality of ginseng is declining together with the amount of harvest being decreased by 15 - 20% due to the heat injuries and diseases from the warming & abnormal climate. Thus, the needs for development of disaster-resistant varieties with better chances of surviving through high temperature, salts and disease are increasing. Therefore, this study is to cultivate disaster-resistant varieties among those selected for their disaster tolerance and salt tolerance through regional adaptation trials. Methods and Results : As a result of examining the growth characteristics of the selected 2 - 5 year old varieties used in the study, among the 5-year old crops, Goryeo 4 and Eumseong 5 showed superior growth in both above and below aerial parts, and among the 4-year old crops, Eumseong 11 and Cheonryang showed superior growth while the growth in the below aerial parts were satisfactory in the order of Cheonryang > Eumseong 10 > Eumseong 11 > Eumseong 9. Among the 3-year old crops, the most superior growth in both above and below aerial parts was observed in Eumseong 14 with the weight of the below aerial part, root diameter and taproot length at 13.8 g, 11.8 ㎝ and 6.2 ㎝ respectively. Among the 2-year old crops, Eumseong 10 showed the most superior growth in both above and below aerial parts. Conclusion : Based on the above results, Goryeo 4 and Eumseong 5 among the 5-year old crops, Eumseong 11 among the 4-year old crops, Eumseong 14 among the 3-year old crops and Eumseon 10 among the 2-year old crops showed the most superior growth among the selected varieties. The growth characteristics of both above and below aerial parts in each year will continuously be monitored.

Real-World National Colonoscopy Volume in Korea: A Nationwide Population-Based Study over 12 Years

Jae Myung Cha,Min Seob Kwak,Hyun-Soo Kim,Su Young Kim,Sohee Park,Geun U Park,Jung Kuk Lee,Soo Jin Kim,Hun Hee Lee,Joo Sung Kim,Won Ho Kim,Big Data Research Group of the Korean Society of Gastroenterol 거트앤리버 소화기연관학회협의회 2020 Gut and Liver Vol.14 No.3

Background/Aims: Little is known about the national colonoscopy volume in Asian countries. This study aimed to assess the national colonoscopy volume in Korea over a 12-year period on the basis of a nationwide population-based database. Methods: We conducted a population-based study for colonoscopy claims (14,511,158 colonoscopies performed on 13,219,781 patients) on the basis of the Korean National Health Insurance Service database from 2002 to 2013. The 12-year national colonoscopy burden was analyzed according to patient age, patient sex, and healthcare facility type. Results: The overall volume of colonoscopy increased 8-fold over the 12-year period. The annual colonoscopic polypectomy rate significantly increased in all patient sex and age groups over the 12-years period (all p<0.001). The yearly colonoscopic polypectomy rate for men was significantly increased compared with that for women (2.3% vs 1.7%, p<0.001) and for the screening-age group compared with that for the young-age group (2.0% vs 1.6%, p<0.001). The yearly colonoscopic polypectomy rate relative to the total colonoscopy volume significantly increased in primary, secondary, and tertiary facilities by 2.4%, 1.9%, and 1.4% during the 12-year period (all p<0.001). In addition, the annual colonoscopy volume covered by high-volume facilities significantly increased by 1.8% in primary healthcare facilities over the 12-year period (p<0.001). Conclusions: Healthcare resources should be prioritized to allow adequate colonoscopic capacity, especially for men, individuals in the screening-age group, and at primary healthcare facilities. Cost-effective strategies to improve the quality of colonoscopy may focus on primary healthcare facilities and high-volume facilities in Korea.

서울시 인구의 공간변화 경향에 관한 연구

金根永,강희진 강남대학교 산학기술연구소 2001 산학기술연구소논문집 Vol.- No.11

Population is an important socio-economic index that explains levels of urban development, current conditions of residential environments, locations of public and private facilities, and socio-economic activities of residents in a city or region. The Seoul city region with over ten million residential population(over 20% share of national population) within an area of 605.5km2(only 0.6% share of national area) has recently experienced the dynamic migration of city residents from central districts to suburb areas at the peak of 10.97 million population in the year of 1992. The objectives of this research are: (1) to investigate the dynamic patterns of Seoul residential population that is already declining with respect to five regional groups of central, northwest, northeast, southeast, and southwest regions provided by 『2011 Seoul City Regional Plan』, (2) to evaluate annual population changes of Seoul jurisdictional Dongs using statistical analyses, and (3) the spatial distributions of Seoul population using a geographic information system. To do this, this research collects annual, Dong-based population data from Seoul statistical yearbooks from the year of 1979 to 1999. This research also applied correlation analysis, hypothesis testing of two non-independent paired data, and spatial analysis using SAS v. 6.12 and Mapinfo v. 4.1. Results from general pattern investigation show that the population of Seoul region is declining since the year of 1992, though the population of the Seoul metropolitan region still increases. This declining population is not the spatial case in one area, but the widely observed, fundamental trend. Results from statistical analyses present that all of correlation analyses and most of hypothesis testing provided significant test outcomes within the 99% significance level. This means that the population number of Seoul city is dramatically changing during most of the study period. The spatial analyses using Mapinfo software clearly show the suburbanization pattern of Seoul population.

지리적 지남력과 관련된 신경학적 요소

김영근 대구보건대학 2005 대구보건대학 論文集 Vol.25 No.-

The purpose of this research is to make clear cognitive components - especially, visual perception and visual memory - related to topographical orientation and which side brain hemisphere tasks charge of topographical orientation. The design of study was double dissociation design. The subject of this study was consisted of right stroke 17, left stroke 13, and unaffected persons 20. The result of research is that topographical orientation is not pure cognitive capacity existing a inherent area but associated several capacities. Especially, topographical orientation was not relevant to visual perception, but was relevant to visual memory much. Prior researches insisted right hemisphere took part in this capacity, but this research person confirmed that topographical orientation is integrated with right and left hemispheres.