뉴스에 나타난 여성스포츠선수 관련 이슈의 변화: 키워드네트워크 활용

조은혜 ( Eunhye Jo ),김수연 ( Suyeon Kim ),김혜진 ( Hyeoi Jin Kim ) 한국체육대학교 체육과학연구소 2021 스포츠사이언스 Vol.39 No.2

이 연구는 키워드 네트워크 분석기법을 활용하여 여성스포츠선수와 관련된 뉴스기사 키워드를 확인하고 이를 통해 20년간 일어난 이슈의 변화를 확인하는 것이 목적이다. 이 연구의 목적을 달성하기 위하여 2001년부터 2021년까지 보도된 2,550개의 뉴스를 수집하여 2001년부터 2005년까지를 1구간, 2006년부터 2010년까지를 2구간, 2011년부터 2015년까지를 3구간, 2016년부터 2021년까지를 4구간으로 구분한 후 키워드 네트워크 분석을 수행하였다. 자료처리는 Ms-Excel과 Netminer 4.2 프로그램을 활용하여 키워드들의 빈도분석, 연결중앙성 분석을 수행하였다. 이 연구의 결론은 다음과 같다. 여성스포츠선수 관련 주요 키워드로는‘여성’, ‘여성스포츠선수’, ‘김연아’, ‘마리아샤라포바’, ‘노는언니’ 등으로 나타났다. 시계열적 관점에서 분석한 여성스포츠선수에 대한 뉴스 이슈의 변화에서는 뉴스의 수가 증가하였다는 것 외 내용에서 는 변화가 없는 것으로 나타났다. 키워드 네트워크 분석 내에서 중복적으로 나타난 결과는 다음과 같다. 첫째, 여성스포츠선수‘미쉘위’, ‘소렌스탐’, ‘세레나윌리엄스’, ‘김연아’ 선수의 연봉, 영향력 있는 선수 선정, 수상 등에 대한 뉴스가 다수 보도되는 것으로 나타났다. 두 번째, ‘김연아’ 선수를 중심으로 한 ‘패션’, ‘드레스’, ‘화제’, ‘광고’ 또는 여성스포츠선수가 출연하는 예능 프로그램에 대한 ‘노는언니’, ‘예능’, ‘박세리’, ‘한유미’, ‘노는브로’등 스타성에 대한 내용의 기사가 보도되는 것으로 나타났다. 본 연구를 통해 여성스포츠선수와 관련된 기사들의 키워드가 경기결과 보다는 스타성, 인기종목에 한정되고 있다는 것을 확인할 수 있었다. Kane and Maxwell의 연구결과가 언론에 영향을 미쳤듯이 이 연구의 결과 또한 언론에서 보도되고 있는 여성스포츠선수들에 대한 뉴스 키워드를 변화시키길 기대해본다. This study aims to utilize keyword network analysis to identify the news article keywords related to female sports players and confirm changes in issues through them. To this study, 2,550 news reports were collected from 2001 to 2021. Keyword network analysis was carried out after dividing four sections: section 1 (2001-2005), section 2 (2006-2010), section 3 (2011-2015), and section 4 (2016-2021). Data processing utilized Ms-Excel and Netminer 4.2 programs to analyze the frequency of keyword and degree centrality. The study results are as follows. Essential keywords related to female sports players include ‘female', ‘female sports players', ‘Yuna Kim', ‘Maria Sharapova', and ‘playful sister'. The change in news issues for female sports players analyzed from a time-series perspective showed no change in content other than the increase in the news. Identical results within keyword network analysis are as follows. First, many news reports on female sports players ‘Michelle Wie West’, ‘Annika Sorenstam’, ‘Serena Williams’ and ‘Yuna Kim’ their annual salary, selection of influential players, and awards are reported. Second, articles on star quality such as ‘Fashion', ‘Dress', ‘Talent', ‘Advertising' or entertainment programs featuring female sports players, such as ‘playful sister', ‘Entertainment', ‘Pak Se-ri', ‘Han Yumi' and ‘playful bro' are reported. This study confirmed that the keywords of articles related to female sports players are limited to sports stars and popularity rather than match results.

Dendritic Cell Dysfunction in Patients with End-stage Renal Disease

Kim, Ji Ung,Kim, Miyeon,Kim, Sinae,Nguyen, Tam Thanh,Kim, Eunhye,Lee, Siyoung,Kim, Soohyun,Kim, Hyunwoo 한국조명·전기설비학회 2017 한국조명·전기설비학회 학술대회논문집 Vol. No.

<P>End-stage renal disease (ESRD) with immune disorder involves complex interactions between the innate and adaptive immune responses. ESRD is associated with various alterations in immune function such as a reduction in polymorphonuclear leukocyte bactericidal activity, a suppression of lymphocyte proliferative response to stimuli, and a malfunction of cell-mediated immunity at the molecular level. ESRD also increases patients' propensity for infections and malignancies as well as causing a diminished response to vaccination. Several factors influence the immunodeficiency in patients with ESRD, including uremic toxins, malnutrition, chronic inflammation, and the therapeutic dialysis modality. The alteration of T-cell function in ESRD has been considered to be a major factor underlying the impaired adaptive cellular immunity in these patients. However, cumulative evidence has suggested that the immune defect in ESRD can be caused by an Ag-presenting dendritic cell (DC) dysfunction in addition to a T-cell defect. It has been reported that ESRD has a deleterious effect on DCs both in terms of their number and function, although the precise mechanism by which DC function becomes altered in these patients is unclear. In this review, we discuss the effects of ESRD on the number and function of DCs and propose a possible molecular mechanism for DC dysfunction. We also address therapeutic approaches to improve immune function by optimally activating DCs in patients with ESRD.</P>

Species Specific Antiviral Activity of Porcine Interferon-α8 (IFNα8)

Kim, Eunhye,Jhun, Hyunjhung,Kim, Joohee,Park, Unjoo,Jo, Seunghyun,Kwak, Areum,Kim, Sinae,Nguyen, Tam T.,Kang, Yongsun,Choi, Insoo,Lee, Joongbok,Kim, Heijun,Kim, Younghyun,Lee, Siyoung,Kim, Soohyun 한국조명·전기설비학회 2017 한국조명·전기설비학회 학술대회논문집 Vol. No.

<P>Interferons (IFNs) have been known as antiviral genes and they are classified by type 1, type 2, and type 3 IFN. The type 1 IFN consists of IFNα, IFNβ, IFNτ, and IFNω whereas the type 2 IFN consists of only IFNγ, which is a key cytokine driving T helper cell type 1 immunity. IFNλ belongs to the type 3 IFN, which is also known as IL-28 and IL-29 possessing antiviral activities. Type 1 IFN is produced by viral infection whereas type 2 IFN is induced by mitogenic or antigenic T-cell stimuli. The IFNτ of bovine was first discovered in an ungulate ruminant recognition hormone. IFNτ belongs to the type 1 IFN with the common feature of type 1 IFN such as antiviral activity. IFNs have been mostly studied for basic research and clinical usages therefore there was no effort to investigate IFNs in industrial animals. Here we cloned porcine IFNα8 from peripheral blood mononuclear cells of Korean domestic pig (<I>Sus scrofa domestica</I>). The newly cloned IFNα8 amino acid sequence from Korean domestic pig shares 98.4% identity with the known porcine IFNα8 in databank. The recombinant porcine IFNα8 showed potent antiviral activity and protected bovine Madin-Darby bovine kidney epithelial (MDBK) cells from the cytopathic effect of vesicular stomatitis virus, but it failed to protect human Wistar Institute Susan Hayflick (WISH) cells and canine Madin-Darby canine kidney epithelial-like (MDCK) cells. The present study demonstrates species specific antiviral activity of porcine IFNα8.</P>

The Pluripotent Status of Porcine Embryonic Stem Cell Lines Derived from Various Origins

Eunhye Kim,Chang-Kyu Lee,Sang-Hwan Hyun 한국동물생명공학회(구 한국동물번식학회) 2014 Reproductive & Developmental Biology(Supplement) Vol.38 No.2s

The pluripotent stem cells can be divided to naïve and primed state according to their pluripotent state. In this study, total 7 primed ESC lines were derived from porcine embryos of various origins, including in vitro fertilized (IVF), parthenogenetic activation (PA) and nuclear transfer (iPS-NT) from a donor cell with induced pluripotent stem cells (iPSC). To characterize ESCs, we performed several approaches including morphological observation, intensive alkaline phosphatase activity, the strongly pluripotency-associated genes such as POU5F1 (formerly known as OCT4), Sox2 and NANOG, immunocytochemistry analysis, the three germ layer associated genes such as AFP (edndoderm), DESMIN (mesoderm), CRABP2 (ectoderm), karyotyping and embryoid body formation. Furthermore, we investigated the XIST gene expression from all female cell lines. Establishment of porcine naïve ESCs, especially iPS-NT ESCs, will make possible sophisticated genetic manipulation to create ideal animal models for pre-clinical research and studies of human diseases. This study will help to approach the goal for establishing naive pluripotent stem cells in pigs.

Latent Tuberculosis Infection Screening and Treatment in Congregate Settings (TB FREE COREA): Demographic Profiles of Interferon-Gamma Release Assay Cohort

Kim Hyung Woo,Min Jinsoo,Choi Joon Young,Shin Ah Young,Myong Jun-Pyo,Lee Yunhee,Yim Hyeon Woo,Jeong Hyunsuk,Bae Sanghyuk,Shim Eunhye,In Hyekyung,Chun Chaemin,Kim Gahee,Kang Ji Young,Lee Sung-Soon,Park 대한의학회 2021 Journal of Korean medical science Vol.36 No.36

In 2017, the Korean government launched an unprecedentedly large-scaled latent tuberculosis infection (LTBI) screening project which covered more than a million individuals in congregate settings. A total of 1,047,689 participants of source population (n = 2,336,157) underwent LTBI testing from 2017 to 2018. The overall LTBI test uptake rate during this project was 44.8%. Workers in daycare centers (83.5%) and kindergartens (78.9%) showed high participation rate. A total of 1,012,206 individuals with valid results of interferongamma release assay (IGRA) were selected to constitute the IGRA cohort. Most of the enrolled participants in the IGRA cohort were in their working age. Approximately, threequarters of total enrolled population were female. Investigating the LTBI prevalence, stages of LTBI care cascade, natural history of LTBI, efficacy of LTBI treatment and cost-effectiveness of LTBI screening are feasible within this IGRA cohort.

Comparative analysis of the proliferative characteristics of primary cancer cells derived from human meningioma

Eunhye Kim,Young Seok Park,Sang-Hwan Hyun 한국수정란이식학회 2016 한국수정란이식학회 학술대회 Vol.2016 No.10

A meningioma is the second most common primary intracranial tumor of the central nervous system. One critical obstacle in meningioma research and preclinical development of novel therapeutic agents is a relative lack of suitable preclinical in vitro and in vivo model systems. In the current study, we assessed the proliferative characteristics of patient derived five primary meningioma cancer cell lines (WHO grade I and II) from brain tumor lesions. All of the meningioma cell lines showed homogenous expression of meningioma marker, VIMENTIN. The GTG-banding analysis determined the existence of different patterns of chromosomal abnormalities in representative cancer cell lines. The almost of the meningioma cell lines showed homogeneously spindle shaped cells, except for M160425 which have two prominent cell morphologies, spindle and round. Population-doubling (PD) was measured for every passage. The M160425 cell line had significantly longer PD time (39.8 ± 0.9 h, P<0.05) than the other meningioma cell lines. Consistent with the PD time, we confirmed that mRNA expression of Ki67, the conventional proliferation marker, was significantly lower in M160425 cell line compared to the other cell lines. The correlation between the PD time and the abundance of Ki67 in the meningioma derived cell lines was negative, indicating higher Ki67 abundance and a shorter PD time. The patient derived meningioma cancer cell lines established in this study might contribute to understanding cancer biology and help the success in the clinic by explaining the slightly different clinical behavior among the patients.

Directed Assembly of High Molecular Weight Block Copolymers: Highly Ordered Line Patterns of Perpendicularly Oriented Lamellae with Large Periods

Kim, Eunhye,Ahn, Hyungju,Park, Sungmin,Lee, Hoyeon,Lee, Moongyu,Lee, Sumi,Kim, Taewoo,Kwak, Eun-Ae,Lee, Jun Han,Lei, Xie,Huh, June,Bang, Joona,Lee, Byeongdu,Ryu, Du Yeol American Chemical Society 2013 ACS NANO Vol.7 No.3

<P>The directed assembly of block copolymer nanostructures with large periods exceeding 100 nm remains challenging because the translational ordering of long-chained block copolymer is hindered by its very low chain mobility. Using a solvent-vapor annealing process with a neutral solvent, which was sequentially combined with a thermal annealing process, we demonstrate the rapid evolution of a perpendicularly oriented lamellar morphology in high molecular weight block copolymer films on neutral substrate. The synergy with the topographically patterned substrate facilitated unidirectionally structural development of ultrahigh molecular weight block copolymer thin filmseven for the structures with a large period of 200 nmleading to perfectly guided, parallel, and highly ordered line-arrays of perpendicularly oriented lamellae in the trenched confinement. This breakthrough strategy, which is applicable to nanolithographic pattern transfer to target substrates, can be a simple and efficient route to satisfy the demand for block copolymer assemblies with larger feature sizes on hundreds of nanometers scale.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2013/ancac3.2013.7.issue-3/nn3051264/production/images/medium/nn-2012-051264_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn3051264'>ACS Electronic Supporting Info</A></P>

Comparative analysis of the proliferative characteristics of primary cancer cells derived from human meningioma

Eunhye Kim,Young Seok Park,Sang-Hwan Hyun 한국동물생명공학회(구 한국동물번식학회) 2016 발생공학 국제심포지엄 및 학술대회 Vol.2016 No.10

Apoptosis in Porcine Pluripotent Cells: From ICM to iPSCs

Kim, Eunhye,Hyun, Sang-Hwan MDPI 2016 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.17 No.9

<P>Pigs have great potential to provide preclinical models for human disease in translational research because of their similarities with humans. In this regard, porcine pluripotent cells, which are able to differentiate into cells of all three primary germ layers, might be a suitable animal model for further development of regenerative medicine. Here, we describe the current state of knowledge on apoptosis in pluripotent cells including inner cell mass (ICM), epiblast, embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs). Information is focused on the apoptotic phenomenon in pluripotency, maintenance, and differentiation of pluripotent stem cells and reprogramming of somatic cells in pigs. Additionally, this review examines the multiple roles of apoptosis and summarizes recent progress in porcine pluripotent cells.</P>

A systematic approach to reducing angular color shift in cavity-based organic light-emitting diodes

Kim, Eunhye,Chung, Jin,Lee, Jaeho,Cho, Hyunsu,Cho, Nam Sung,Yoo, Seunghyup Elsevier Science B.V., Amsterdam. 2017 Organic electronics Vol.2017 No.48