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다구치법에 의한 고 규소 내산주철의 용해주조공정 최적화
신제식,이상목,문병문,김정철,한동운,백승한 대한금속재료학회 2005 대한금속·재료학회지 Vol.43 No.2
In this study, Taguchi method, one of the design tools of experiments, was applied to optimize casting process parameters of the high silicon corrosion-resistant iron. Three casting process parameters such as melting temperature, rare earth metal (mischmetal) addition, and pouring temperature were chosen. Using SN (signal-to-noise) ratio calculated from ultimate tensile strength of each experimental casting run, the relationship between the casting parameters and mechanical properties was statistically evaluated. The casting condition of a melting temperature of 1,650℃, 0.2% rare earth metal addition, and a pouring temperature of 1,350℃ led to an excellent ultimate tensile strength above 11 kgf/mm², which is beyond the industrial criterion. The effects of the casting parameters on mechanical properties and corrosion resistance were further confirmed by combined analysis of fractography, hydrogen content determination, microscopic test, and acid resistance test. (Received August 23, 2004)
신병철,정원명,박상현,이규일,박경배,박진호 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.2
Manufacturing facilities of the pharmaceuticals must meet certain level of the cleanness required so that foreign substances such as dust, moisture, heat, microorganism, or virus do not contaminate the product. In case of radiopharmaceuticals for medical treatment and diagnosis, not only should the operators and environment be protected from radiation but also need to be isolated from the foreign contaminant. Therefore, manufacturing facilities for radiopharmaceuticals must satisfy the design standards of both hot cell and clean room which are specified by GNP. However, standards of maintaining negative pressure for preventing spread of radioactive contaminant in isolated facilities conflict with the standards of maintaining positive pressure for keeping cleanness. To solve this problem, are pressure of hot cell was designed lower than in the adjacent area to meet standards of the radiation safety. To keep higher cleanness in certain part of the hot cell for filling, minimal relative positive pressure allows. In order to effectively maintain the cleanness that is required for production of Tc-99m generator, which takes 70% of whole demand of radiopharmaceuticals, the rooms placed in each side of production room are used as a buffer area and three lead hot cells are installed in production room. In this research, we established the appropriate engineered design concept for Tc-99m generator manufacturing facility, which satisfies both GMP cleanness standard for preventing particles, bacteria, other contaminants and the regulations of radiation safety for supervising and controlling the amount of radiation exposure and exhausted radioactivity. And the concept of multi-buffer zones is introduced to apply negative air pressure for hot cell with first priority and to continue relative positive air pressure for clean room.
유지 투석중인 만성 신부전환자에서 허혈성 심질환의진단 지표로서의 심장트로닌-I의 유용성
신병철,강대웅,정지용,류봉관,서영욱,김정인,김범윤,김현리,정종훈 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.1
Background : Coronary disease is highly prevalent in patient with end stage renal disease (ESRD) and account for much of their observed morbidity and mortality. Troponin-I consistently maintains a high sensitivity and specificity and is most sensitive marker for ischemic heart disease (IHD). Method : We examed 49 hernodialyzed patients (22 male, 27 female) without evidence of acute coronary syndrome (ACS) for 6 months. Biochemical markers were measured in serial predialysis blood samples. For analysis, we used two cardio-specific assays for troponin-T (cTnT) as well as for troponin-I (cTnI) and compared the results with CK-MB (reference value ≤ 4.0 ng/mL) concentration. Results : Myocardial ischemia was observed in 47% (23/49) of patients. cTnT level above 0.1 ng/mL. and cTnI level above 0.5 ng/mL, were observed in 22% (11/49) and 20% (10/49) of patients respectively. cTnI revealed significantly higher positive rate in patients with myocardial ischemia than the patients without myocardial ischemia (43 % vs 30%) (p<0.05). cTnT and CK-MB revealed no difference in positive rate between the patients with and without myocardial ischemia (cTnT : 30% vs 15% and CK-MB : 30% vs 19%). The sensitivity and specificity of cTnI to myocardial ischemia were higher than those of cTnT and CK-MB (sensitivity 43% vs 30% and 30%. specificity 100% vs 85% and 81%). Conclusion: Both cTnT and cTnI are useful in ruling out myocardial injury in chronic renal failure patients. But. cTnI is a more sensitivity and excellent specificity of ischemic heart disease than cTnT and CK-MB in hemodialyzed patients. In patients with ischemic heart disease, the presences of DM and advanced age were higher than those in patients without ischemic heart disease (p<0.05). Among the baseline characteristics old age, elevated LDH and diabeties were significant more frequent in the patients with elevation of cardiac troponin-I (p>0.5 ng/mL) than those with cardiac troponin-I (p<0.5 ng/mL), p=0.038, p=0.049, and p=0.045, respectively. Our results suggest that these cTnI is the potential diagnostic marker for the prediction of IHD in ESRD patients.
수술적으로 치료한 통증을 동반한 흉추부의 후외상성 Schmorl씨 결절 : 2례 보고 Report of Two Cases
신병준,이재철,송화용,정석봉,권계원,조영일,김연일 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2
Study Design : Two patients who had painful Schmorl's node at thoracic level from acute trauma were adopted and taken operation for its treatment Objectives : To document the effect of operation for the treatment of painful Schmorl's node at thoracic level summary of background data : Schrmorl's nodes are common spinal lesion generally believed to be asymptomatic, but in some cases there were painful symptom by Schmorl's node. This case report is to explain the effect of operative treatment for the painful Schmorl's node. Methods : Two patients were adopted who had traumatic painful Schmorl's node at thoracic level for our case report. They were treated conservative methods at first but it's effect were poor, so they were taken anterior decompression and fusion, and checked back pain symptom. Result : In all two patients, the symptom of back pain by Schmorl's nodes at thoracic level was almost subsided. conclusion : For the treatment of traumatic painful Schmorl's node, most of surgeon says that conservative treatments were treatment of choice, but operative treatments are also benefit to subsidence of back pain by Schmorl's node.
一部農村地域 靑少年層의 成長發育과 體容積·體脂肪量에 關한 硏究
申吉洙,朴喆斌,南炳執,朴淳永 圓光大學校 附設 體力科學硏究所 1981 體力科學硏究 Vol.4 No.-
A study on 3,663 middle and high school students(1790 boys and 1873 girls) in rural areas of Jeonla Province was conducted from May I to July 30 in 1978 for assessing their physical growth and development in terms of physical and nutritional indices, and the correlation between body weight and volume is obtained. Following are the results. A. Physical Growth and Development. 1. Rapid growth of physical grovth in terms of body height, weight, chest-gi-rth and sitting height has been observed among 17 year-old boys and 15 year-old girls. Growth in terms of physical growth and development turned out to be slower among students of higher ages, irrespective of male of female. 2. The maximum annual growth rates were as follows; Body Height ; 6.0㎝ during the age 16∼17 for boys. 5.2㎝ during the age 12∼13 for girls. Body weight ; 6.4㎝ during the age 14∼15 for boys. 6.0㎝ during the age 12∼13 for girls. Chest-Girth ; 4.3㎝ during the age 14∼15 for boys. 5.0㎝ during the age 12∼13 for girls. Sitting Height ; 3.3㎝ during the age 13∼14 for boys. 2.8㎝ during the age 12∼13 for girls. B. Various Indices about Physical Growth and Development. 1. The lineal increase of relative body weight was shown in both sex groups belonging to the ages 11∼17. 2. As for relative chest girth, it is small in the age of 15 for boys and 12 for girls, but when they are 16 and 13, respectively, it becomes normal. 3. In both sex groups, the growth rate was shown to be constant nearly to the same degree. 4. Rohrer index was 1.1∼1.2 for boys and 1.2∼1.3 for girls. 5. The Kaup index was lower than 2.0 for boys under 15 years of age and for girls under 14 years of age. It become higher than 2.0 after they reach 16 and 15, respectively. 6. Vervaeck index was 76.9∼89.7 for boys and 78.5∼89.0 for girls. For both cases it increased with age. 7. Pelidisi index of the nutitional status was obtained 91∼92 for boys and 89∼95 for girls. C. Correlation between Body Weight and Body Height. The correlation coefficient between body height and weight is as show in Table 12. D. Standard Body Weight by Age. The equation of the standard body weight is as shown in Table 12. E. Body Volume. Mean values of body surface area(㎡), body volume(ℓ), and body density(㎏/ℓ) were calculated by an indirect method from body height and weight, as shown in Table 13. F. Body Fat Weight. The percentage of mean body fat content was 10.84±1.83 to 13.88±2.15% for boys and 22.28±2.55 to 25.60±3.99% for girls, respectively. G. Correlation between relative Body Weight and Body Volume by age. The correlation coefficient and equation between relative body weight and volume by age are an shown in Table 14.
申仁澈,金成鍾,鄭炳善 단국대학교 1995 論文集 Vol.29 No.-
Recently the application of the digital image processing has been increased with technical advances in digital computers. It is necessary to compress the digital image data in order to store and transmit it with real time. It is possible to redisplay the relatively exact image and decrease bandwidth of transmission path with the reduced information by compression. JPEG in ISO and CCITT defines the standard compression and restoration algorithm for grayscale and color still image. In this paper, we propose a method of decreasing higher frequency component and increasing spatial redundancy in image, and the compression ratio. In order to decrease higher frequency components of the images, various filters were used in the preprocessing. Compression ratio and processing time were compared. Results shows the enhanced compression ratio without damage of image quality by using filter in JPEG.
신용철,이병규,김선자,김향순 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.2
Hexavalent chromium, Cr(Ⅵ),may reduce on polyvinyl chloride (PVC) filter during air sampling. This study was conducted to cstimate the reduction rate of Cr(Ⅵ) on PVC filter during air sampling and an correction equation for th loss of Cr(Ⅵ) by feduction in an industrial plating process. The reduction of Cr(Ⅵ) was progressed rapidly in 60 minutes and slowly thereafter. The empirical reduction rate of Cr(Ⅵ) (Y) over sampling time (X, min) was the following : Y= 0.916 -0.0208√x (r=0.73, p〈0.05). The loss of Cr(Ⅵ) caused by reduction during sampling can be corrected using the following empirical equation : Sc = S x 1/Y. where Sc = corrected value, S = analytical result, and Y= reduction rate of Cr(Ⅵ).
주유철,이동민,양종태,신병철,임태영,서정균,정기영,최동헌,김원,조영신,고희관 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2
Background and Objectives : Palindromic rheumatism (PR) is known to be triggered without any obviously inciting events in most patients, although, in a few cases, attacks have been noted to relate to another events such as weather change, childbirth, ingestion of certain foods, or over-exercise. The aim of this study was to characterize the triggering factors on palindromic attacks. Materials and Methods : We evaluated sixty-four patients with PR for the presence of triggering factors and the relationship between attacks and triggering factors by interview of patients. We considered that there was an probable association between episodes and PR, if episodes within 24 hours prior to PR had triggered at least 50% of all attacks and a definite association between episodes and PR, if episodes within 24 hours prior to PR had triggered 100% of all attacks. Results : In 15 patients (35.9%), there was a possible association between episodes of PR and initiating events. In 8 patients (12.5%), there was a definite association between episodes of PR and initiating events. The triggering factors were physical over-activity including exercise (19/64: 29.7%), foods, such as rawfish, crab, and chicken, including alcohol (19/96: 19.8%). However, there were no difference between the groups with and without the triggering factor in sex ratio, duration and onset of PR, the positive rate of rheumatoid factor and involved sites. Conclusion : Our observations showed that PR was triggered by physical over-activity more than in previous reports and hypersensitivity to foods was a causative factor in some patients with PR. However, patients with triggering factors had a similiar clinical profile to patients without triggering factors.
최병오,신명철 한국기초조형학회 2003 기초조형학연구 Vol.4 No.1
유아용 승용완구 디자인연구 과정에서 얻어진 구체적인 결론을 요약하면 다음과 같다. 첫째, 안전성-무독성의 재료를 사용하고 날카롭고 뾰족한 부분이 없어야 하며, 유아가 삼킬 수 있을 정도의 작은 크기의 부품이 없어야 한다. 둘째, 세척성-청결을 유지할 수 있도록 세척 가능한 재료를 사용해야 한다. 셋째, 내구성-쉽게 깨어지거나 변형되지 않는 재질을 사용해야 한다. 넷째, 매력적, 흥미성-유아의 호기심을 유발하여 놀이하고 싶은 마음이 들게 하고 놀이를 지속하고 싶은 마음이 들게 해야 하며 모양과 색상이 미적으로 아름다워야 한다. 또한 놀이 방법이 너무 단순하지 않고 다양한 방법으로 활용이 가능해야 한다. 다섯째, 조작성-세발 자전거의 크기와 무게가 유아가 조작하기에 적절하고, 조작방법이 복잡하지 않고 어렵지 않아야 한다. 여섯째, 교육적 기능-여러 가지 감각 경험을 제공하고, 탐색활동을 자극해야 한다. 일곱째, 경제성-가격이 너무 비싸지 않고 다양한 용도로 활용될 수 있어야 한다. This study summarizes the several conclusions in developing tricycle design as follows; First, Safety - The toys for infants should use nontoxic materials, have no sharp parts, and have no parts as small as infants may swallow them. Second, Washing - The toys for infants should use washable materials to maintain cleanliness. Third, Durability - The toys for infants should use the materials that are not easily broken of transformed. Fourth, Attraction & Curiosity - The toys for infants should induce infants to have curiosity for them and thereby make infants want to play with them continuously, and the toy's shape and color should be beautiful. In addition the play method should not be too simple and they should be utilized in various ways.Fifth, Operation - The size and weight of tricycle should be proper for infants to operate, and the operation method should not be too complicated or difficult. Sixth, Educational Function - The toys for infants should provide several senses' experience, simulate search activity and provide the opportunity of problem-solving, and stimulate their imagination and creatively. Seventh, Economical Efficiency - The toys for infants should not be too expensive and can be utilized in various uses.