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      • KCI등재

        Dynamic Task Scheduling Via Policy Iteration Scheduling Approach for Cloud Computing

        ( Bin Hu ),( Ning Xie ),( Tingting Zhao ),( Xiaotong Zhang ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.3

        Dynamic task scheduling is one of the most popular research topics in the cloud computing field. The cloud scheduler dynamically provides VM resources to variable cloud tasks with different scheduling strategies in cloud computing. In this study, we utilized a valid model to describe the dynamic changes of both computing facilities (such as hardware updating) and request task queuing. We built a novel approach called Policy Iteration Scheduling (PIS) to globally optimize the independent task scheduling scheme and minimize the total execution time of priority tasks. We performed experiments with randomly generated cloud task sets and varied the performance of VM resources using Poisson distributions. The results show that PIS outperforms other popular schedulers in a typical cloud computing environment.

      • SCOPUSKCI등재
      • SCISCIESCOPUS

        Optically tunable Seebeck effect from intramolecular proton-transfer materials in organic vertical thin-film thermoelectric device

        Hu, Dehua,Liu, Qing,Tisdale, Jeremy,Nam, Haerim,Park, Soo Young,Wang, Hsin,Urbas, Augustine,Hu, Bin Elsevier 2015 ORGANIC ELECTRONICS Vol.26 No.-

        <P><B>Abstract</B></P> <P>This paper reports Seebeck effects from optically-induced intramolecular proton-transfer HPI-Cbz molecules based on vertical electrode/organic film/electrode thin-film devices. We observed large Seebeck coefficients of 428μV/K and 390μV/K from HPI-Cbz based thin-film devices at 60°C when proton-transfer was induced by the photoexcitation of a 325nm laser with an intensity of 12mW/cm<SUP>2</SUP> and 6mW/cm<SUP>2</SUP> respectively. Under dark condition without proton transfer occurring, the Seebeck coefficient was measured to be 342μV/K at 60°C. The Seebeck coefficient enhancement by the induced intramolecular charge transfer can be attributed to the enhanced polarization difference between high- and low-temperature surface due to the stronger electron–phonon coupling followed with the proton-transfer in HPI-Cbz under photoexcitation, and the strength of electron–phonon coupling is proportional to the photoexcitation intensity. The enhanced temperature-dependent electrical polarization between the high and low-temperature surfaces acts as an additional driving force to diffuse the majority charge carriers for the development of a large Seebeck effect. Therefore, using intramolecular proton-transfer presents an effective approach of enhancing Seebeck effect in organic materials.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Photoinduced proton-transfer states lead to enhancement on Seebeck coefficients. </LI> <LI> Photoinduced proton-transfer states lead to enhancement on electrical conductivity. </LI> <LI> Temperature-dependent polarization acts as a new driving force for Seebeck effect. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • SCOPUSKCI등재

        Triterpenoid Saponins from Elsholtzia bodinieri

        Hu, Hao-Bin,Zheng, Xu-Dong,Hu, Huai-Sheng,Jian, Yu-Feng Korean Chemical Society 2007 Bulletin of the Korean Chemical Society Vol.28 No.9

        A new oleanane-type triterpenoid estersaponin, bodinierin C (1), along with two known saponins, mazusaponin I (2) and ciwujianoside C (3), were isolated from the water-soluble part of the root barks of Elsholtzia bodinieri. The structure of bodinierin C was characterized by spectroscopic means and chemical hydrolysis as 3β -Ocaffeoyl- 23-hydroxylechinocystic acid 28-O-α -L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6)-β- D-glucopyranosyl ester. The known compounds were identified by comparing their spectral data with those of authentic samples or data reported in the literature. All compounds were firstly isolated from Elsholtzia bodinieri family.

      • Predictive V16alue of Thymidylate Synthase Expression in Gastric Cancer: A Systematic Review with Meta-analysis

        Hu, Hua-Bin,Kuang, Lei,Zeng, Xiao-Min,Li, Bin,Liu, En-Yi,Zhong, Mei-Zuo Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1

        Purpose: The relationship between thymidylate synthase (TS) expression and outcomes in gastric cancer (GC) patients remains controversial, although most studies reported poor survival and reduced response to fluoropyrimidine were related to high TS in tumors. We carried out a systematic review of the literature with meta-analysis to estimate the predictive value of TS expression from published studies. Methods: We indentified 24 studies analysing the outcome data in gastric cancer stratified by TS expression. Effect measures of outcome were hazard ratios (HRs) for overall survival (OS) and event-free survival (EFS), or the odds ratio (OR) for overall response rate (ORR). HRs and ORs from these eligible studies were pooled using random-effects meta-analysis. Results: Fifteen studies investigated outcomes in a total of 844 patients with advanced GC, and nine studies investigated outcomes in a total of 1,235 patients with localized GC undergoing adjuvant therapy. Meta-analysis of estimates showed high TS expression was significantly associated with poor OS in the advanced setting (HR: 1.43, 95%CI: 1.08 - 1.90), and poor EFS in the adjuvant setting (HR: 1.53, 95%CI: 1.01 - 2.32). Subgroup analysis demonstrated TS expression to haves even greater value in predicting OS, EFS and ORR in advanced GC patients treated with fluoropyrimidine monotherapy (HR for OS: 2.32, 95%CI: 1.53 - 3.50; HR for EFS: 1.76, 95%CI: 1.19 - 2.60; OR for ORR: 0.32, 95%CI: 0.11 - 0.95). Conclusion: High levels of TS expression were asssociated with a poorer OS for advanced GC patients compared with low levels. In the adjuvant setting, high TS expression was also associated with a worse EFS. Additional studies with consistent methodology are needed to define the precise predictive value of TS.

      • SCOPUSKCI등재

        Synthesis and Evaluation O-Benzyl Oxime-ether Derivatives Containing β-Methoxyacrylate Moiety for Insecticidal and Fungicidal Activities

        Hu, Zhi-Bin,Luo, He-An,Wang, Xiao-Guang,Huang, Ming-Zhi,Huang, Lu,Pang, Huai-Lin,Mao, Chun-Hui,Pei, Hui,Huang, Chao-Qun,Sun, Jiong,Liu, Ping-Le,Liu, Ai-Ping Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.4

        In attempt to lead compounds exhibiting both insecticidal and fungicidal activities, a series of O-benzyl oximeether derivatives were designed and synthesized by introducing ${\beta}$-methoxyacrylate pharmacophore into a scaffold. The insecticidal activity against Aphis fabae and the fungicidal activity against Erysiphe graminis were screened. The title compounds exhibited remarkable insecticidal and fungicidal activities. The most potent compound 6d was identified. Its insecticidal $LC_{50}$ against A. fabae is 6.4 mg/L, which is lower than that of chlorfenapyr (19.4 mg/L) and even close to the level of imidacloprid (4.8 mg/L). Its fungicidal $EC_{90}$ in preventive and curative treatment against E. graminis are 2.2 and 4.8 mg/L, respectively, which are lower than azoxystrobin (7.0 and 5.9 mg/L). These results indicate that compound 6d can be considered as a lead for further developing new O-benzyl oxime-ether typed candidates with both fungicidal and insecticidal activities.

      • SCOPUSKCI등재
      • KCI우수등재

        SNS는 사회관계를 변화시키는가?

        후빈(Bin Hu),조주은(Jooeun Cho) 한국사회학회 2017 韓國社會學 Vol.51 No.2

        카스텔을 비롯한 여러 사회학자들은 인터넷이 관심과 정보를 공유하는 개인 중심의 사회관계를 확장시킬 것으로 예측하였고, SNS는 이를 가속화할 것으로 기대되었다. 이런 측면에서 SNS의 확산은 연고가 강력한 사회자본으로 작동하는 한국사회에 큰 변화를 가져올 수 있다. 그러나 이러한 예측은 기술결정론의 관점에 기반하고 있다. 본 연구에서는 기술의 사회적 구성주의의 관점에서 SNS 이용행태의 사회적 차이에 주목하고, 그것이 각 사회에서 지배적으로 작동해 온 사회자본의 차이에 기인함을 밝히고자 하였다. 이를 위해 연고와 꽌시와 같이 지배적 사회자본의 영향력이 뚜렷한 한국과 중국사회를 선택하여 면접조사를 실시하였다. 분석 결과, 지배적 사회자본은 SNS의 선택과 이용에 큰 영향을 미쳤다. 그리고 SNS의 확산은 오프라인에서 지배적인 사회자본을 강화하는 결과를 초래하였다. 한국사회에서는 폐쇄형 SNS가 친밀한 연고관계를 더욱 돈독하게 만들고, 반개방형 SNS는 연고관계의 범위를 확장시키면서 연고의 지배력을 강화하였다. 개방형 SNS는 이용되지 않고, 반개방형 SNS에서 새로운 사회자본이 형성되지 않으면서 연고는 더욱 공고해졌다. 중국사회에서도 개방형 SNS는 거의 이용되지 않았으나, 반개방형 SNS에서는 새로운 사회자본이 형성되고 꽌시로 발전하였다. 결론적으로 SNS가 개인중심의 사회관계를 형성하고 교량형 사회자본을 확대할 수 있는 기술적 가능성을 제공하였지만, 사회적 요인 때문에 기술적 가능성이 기대만큼 사회관계를 변화시키지 않았다. 역으로 SNS는 예상하지 못한 방식으로 기존의 사회관계를 강화하고 있었다. Many sociologists including Manuel Castells predicted that the internet would expand social relationships of the individuals sharing interests and information, and that the social networking services (i.e., SNS) would accelerate this process. In this regard, the expansion of SNS might result in significant social changes in Korea where ‘Yongo’ is a form of strong social capital. Such a prediction, however, is based on technological determinism. Employing the perspective of social construction of technology, the current study focuses on the societal differences in SNS usage behavior in Korea and China, and attempts to reveal that such differences are due to the type of dominant social capital in each society. As Korea and China have dominant social capital form in ‘Yongo’ and ‘Guanxi’, respectively, we conducted in-depth interviews with the subjects from these two countries for a comparative study. The findings are as follows: The type of dominant social capital affects: the what and how in terms of using certain social networking services. The expansion of SNS strengthens already existing offline social capital. In Korean society, closed SNS further tightens existing Yongo, and semi-open SNS expands the range of Yongo, thus strengthening the dominance of Yongo-relationship. That is, open SNS is not practiced, and semi-open SNS strengthens Yongo without forming new social capital. In China, semi-open SNS forms new social capital, which is developed into Guanxi. Open SNS is not utilized in China, either Although SNS provides technical possibility of forming individual-centered social relationships and expanding bridging social capital, the technical possibility, due to social factors, does not significantly change social relationships. In contrast, SNS strengthens existing social relationships in unexpected ways.

      • KCI등재

        Intensity-Modulated Radiotherapy versus Three-Dimensional Conformal Radiotherapy in Definitive Chemoradiotherapy for Cervical Esophageal Squamous Cell Carcinoma: Comparison of Survival Outcomes and Toxicities

        Nai-Bin Chen,Bo Qiu,Jun Zhang,Meng-Yun Qiang,Yu-Jia Zhu,Bin Wang,Jin-Yu Guo,Ling-Zhi Cai,Shao-Min Huang,Meng-Zhong Liu,Qun Li,Yong-Hong Hu,Qi-Wen Li,Hui Liu 대한암학회 2020 Cancer Research and Treatment Vol.52 No.1

        Purpose The purpose of this study was to compare the survival and toxicities in cervical esophageal squamous cell carcinoma (CESCC) treated by concurrent chemoradiothrapy with either three-dimensional conformal radiotherapy (3D-CRT) or intensity-modulated radiotherapy (IMRT) techniques. Materials and Methods A total of 112 consecutive CESCC patients were retrospectively reviewed. 3D-CRT and IMRT groups had been analyzed by propensity score matching method, with sex, age, Karnofsky performance status, induction chemotherapy, and tumor stage well matched. The Kaplan- Meier method and Cox proportional hazards model were used for overall survival (OS) and progression-free survival (PFS). Toxicities were compared between two groups by Fisher exact test. Results With a median follow-up time of 34.9 months, the 3-year OS (p=0.927) and PFS (p=0.859) rate was 49.6% and 45.8% in 3D-CRT group, compared with 54.4% and 42.8% in IMRT group. The rates of grade ! 3 esophagitis, grade ! 2 pneumonitis, esophageal stricture, and hemorrhage were comparable between two groups, while the rate of tracheostomy dependence was much higher in IMRT group than 3D-CRT group (14.3% vs.1.8%, p=0.032). Radiotherapy technique (hazard ratio [HR], 0.09; 95% confidence interval [CI], 0.01 to 0.79) and pretreatment hoarseness (HR, 0.12; 95% CI 0.02 to 0.70) were independently prognostic of tracheostomy dependence. Conclusion No survival benefits had been observed while comparing IMRT versus 3D-CRT in CESCC patients. IMRT with fraction dose escalation and pretreatment hoarseness were considered to be associated with a higher risk for tracheostomy dependence. Radiation dose escalation beyond 60 Gy should be taken into account carefully when using IMRT with hypofractionated regimen.

      • KCI등재

        Constituents of the Root of Anemone tomentosa

        Hao-Bin Hu,Xu-Dong Zheng,Yu-Feng Jian,Jian-Xin Liu,Ji-Hua Zhu 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.7

        A new diterpene glycoside, tomentoside I (1), along with eleven known compounds, including the four coumarins, 4,5-dimethoxyl-7-methylcoumarin (2), 4,7-dimethoxyl-5-methylcoumarin (3), isofraxidin (4) and fraxidin (5) as well as the seven triterpenoids, oleanolic acid (6), oleanolic acid 3-O-α-L-arabinopyranoside (7), oleanolic acid 3-O-β-D-galactopyranosyl-(1→3)-β-Dglucopyranoside (8), hederagenin 3-O-α-L-arabinopyranoside (9), betulinic acid (10), 18-hydroxyursolic acid (11) and 2α,3β,23-trihydroxyurs-12-en-28-oic acid (12) were isolated from the ethanolic extract of the root of Anemone tomentosa and their chemical structures were elucidated by spectroscopic methods. The antimicrobial activities of compounds 1-12 were measured using the agar disc-diffusion method. Also, their antioxidant activities against 1,1-diphenyl-2-picrylhydrazyl (DPPH) were evaluated.

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