Risk factors of medication-related osteonecrosis of the jaw: a retrospective study in a Turkish subpopulation

Onur Ş,ahin,Onur Odabaş,Toghrul Aliyev,Birkan Tatar 대한구강악안면외과학회 2019 대한구강악안면외과학회지 Vol.45 No.2

Objectives: Medication-related osteonecrosis of the jaw (MRONJ) is a well-known side effect of certain drugs that are used to influence bone metabolism to treat osteometabolic disease or cancers. The purpose of our study was to investigate how high-concentration and low-concentration bisphosphonate (BP) intake affects the disease severity. Materials and Methods: Data collected from the medical records of 52 patients treated with BPs, antiresorptive, antiangiogenic drugs and diagnosed with MRONJ were included in this study. Age, sex, type of systemic disease, type of drug, duration of drug treatment, jaw area with MRONJ, drug administration protocol, and MRONJ clinical and radiological findings were obtained. Patients were divided into two groups: anti-neoplastic (Group I, n=23) and anti-osteoporotic (Group II, n=29). Statistical evaluations were performed using the IBM SPSS ver. 21.0 program. Results: In both groups, more females had MRONJ. MRONJ was found in the mandibles of 30 patients (Group I, n=14; Group II, n=16). When we classified patients according to the American Association of Oral and Maxillofacial Surgeons staging system, significant differences were seen between groups (χ 2 =12.23, P<0.01). More patients with advanced stage (stage 2-3) MRONJ were found in Group I (60.9%). Conclusion: According to our results, high-concentration BP intake, age and duration of drug intake increased disease severity.

Some Properties of Fresh and Ripened Traditional Akcakatik Cheese

Bedia Ş,imş,ek,Yasin Tuncer 한국축산식품학회 2018 한국축산식품학회지 Vol.38 No.1

Akcakatik cheese (yogurt cheese) is produced by drying strained yogurt with or without adding cloves or black cumin. The main objective of this study was to detect the properties of both fresh and ripened Akcakatik cheeses and to compare them. For this purpose the biogenic amine content, volatile flavor compounds, protein degradation level, chemical properties and some microbiological properties of 15 Akcakatik cheese samples were investigated. Titratable acidity, total dry matter, NaCl, total nitrogen, water soluble nitrogen, ripened index, histamine, diacetyl and acetaldehyde levels were found to be higher in ripened cheese samples than in fresh cheese samples. On the other hand, the clove and black cumin ratios were found to be higher in the fresh cheese samples. Sodium dodecyl sulphate polyacrylamide gel electropherograms of cheese samples showed that protein degradation was higher in ripened cheese samples than in fresh samples, as expected. The dominant Lactic acid bacteria (LAB) flora of Akcakatik cheese samples were found to be Streptococcus salivarius subsp. thermophilus and Lactobacillus delbrueckii subsp. bulgaricus.

Prevalence of Clostridium difficile Isolated from Beef and Chicken Meat Products in Turkey

Ş;eyma Ş;eniz Ersöz;Serap Coşansu 한국축산식품학회 2018 한국축산식품학회지 Vol.38 No.4

The concern about the possibility of food can be a vehicle for the transmission of Clostridium difficile to humans has been raised recently due to the similarities among the strains isolated from patients, foods and food animals. In this study, therefore, the prevalence of C. difficile was investigated in beef and chicken meat products collected from 57 different butcher shops, markets and fast food restaurants in Sakarya province of Turkey. Two out of 101 samples (1.98%) was positive for C. difficile indicating a very low prevalence. The pathogen was isolated from an uncooked meatball sample and a cooked meat döner sample, whereas not detected in chicken meat samples. The meatball isolate was resistant to vancomycin and tetracycline, while the cooked meat döner isolate was resistant to vancomycin and metronidazole. Both isolates were sensitive to moxifloxacin and clindamycin. Toxins A and B were not detected. This study reveals the presence of C. difficile in further processed beef products in Turkey.

Protective Effect of Aqueous Garlic Extract Against Renal Ischemia/Reperfusion Injury in Rats

Göksel Ş;ener,Levent Kabasakal,Özer Ş;ehirli,Ş;ule Çetinel,Esra Cikler,Nursal Gedik 한국식품영양과학회 2005 Journal of medicinal food Vol.8 No.3

Design of Neural Networks Model for Transmission Angle of a Modified Mechanism

Ş;ahin Yildirim,Selçuk Erkaya,Ş;ükrü Su,íbrabim Uzmay 대한기계학회 2005 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.19 No.10

This paper discusses Neural Networks as predictor for analyzing of transmission angle of slider-crank mechanism. There are different types of neural network algorithms obtained by using chain rules. The neural network is a feedforward neural network. On the other hand, the slider-crank mechanism is a modified mechanism by using an additional link between connecting rod and crank pin. Through extensive simulations, these neural network models are shown to be effective for prediction and analyzing of a modified slider-crank mechanism’s transmission angle.

Evaluation of the alignment efficiency of nickeltitanium and copper-nickel-titanium archwires in patients undergoing orthodontic treatment over a 12-week period: A single-center, randomized controlled clinical trial

Burcu Aydın,Neslihan Ebru Ş,enış,ık,Ö,zgü,r Koş,kan 대한치과교정학회 2018 대한치과교정학회지 Vol.46 No.3

Objective: The aim of this trial was to compare the alignment efficiency and intermaxillary arch dimension changes of nickel-titanium (NiTi) or copper-nickeltitanium (CuNiTi) round archwires with increasing diameters applied sequentially to the mandibular arch. Methods: The initial alignment phase of fixed orthodontic treatment with NiTi or CuNiTi round archwires was studied in a randomly allocated sample of 66 patients. The NiTi group comprised 26 women, 10 men, and the CuNiTi(27℃) group comprised 20 women, 10 men. The eligibility criteria were as follows: anterior mandibular crowding of minimum 6 mm according to Little’s Irregularity Index (LII), treatment requiring no extraction of premolars, 12 to 18 years of age, permanent dentition, skeletal and dental Class I malocclusion. The main outcome measure was the alignment of the mandibular anterior dentition; the secondary outcome measure was the change in mandibular dental arch dimensions during 12 weeks. Simple randomization (allocation ratio 1:1) was used in this single-blind study. LII and mandibular arch dimensions were measured on three-dimensional digital dental models at 2-week intervals. Results: No statistically significant difference was observed between NiTi and CuNiTi according to LII (p > 0.05). Intercanine and intermolar arch perimeters increased in the CuNiTi group (p < 0.001). Inter-first premolar width showed a statistically significant interaction in week × diameter ×application (p < 0.05). Conclusions: The effects of NiTi and CuNiTi round archwires were similar in terms of their alignment efficiency. However, the intercanine and intermolar arch perimeters, and the inter-first premolar width changes differed between groups.

Sustainable Growth of Turkish Tourism Sector and Alternative Methods in Finance

Mehmet YAZICI,Ayş,e Yİ,Ğ,İ,T Ş,AKAR 한국문화관광학회 2011 문화관광연구 Vol.13 No.2

According to the World Tourism Organization-Tourism Highlights 2011 survey in 2010 World’s top destinations, Turkey has the seventh most tourists, with 27 million visitors and the tenth highest revenue from tourism, earning $20,8 billion. In first quarter of 2011 the negative effects of economic and political developments in Eastern Europe, North Africa and the Middle East caused early booking cancellations and destination changes in favor of Turkey. If we compare the first quarter of 2011 with the previous year, there was an increase of international tourists to Turkey of 17%, and an increase in tourism revenues of 28.5% in dollars. Turning this positive trend into a sustainable growth in tourism sector and achieving the goal of 63 million tourists and 86 billion dollars in year 2023 as projected by the Ministry of Culture and Tourism depends on improving alternative methods in sectoral finance and support of medium and long-term investments by the government. The subject of this study is to propose alternative methods for tourism finance in Turkey. The first part of this study discusses the current loan structure of tourism sector; the second part discusses existing tax and incentive schemes; the third part analyzes of the alternative finance methods which are used around in the world; and the last part discusses solution proposals for sustainable growth.

Examining The Spatial Distribution of Festivals in Turkey

Deniz YÜ,NCÜ,Semra GÜ,NAY AKTAŞ 세계문화관광학회 2015 International Journal of Culture and tourism Resea Vol.8 No.1

Festivals have become a strong demand generating factor in recent years. They not only contribute to tourism, travel, leisure and hospitality industries but also act as an important tool to attain social, economical, environmental objectives of communities. This study investigates the spatial dependence of festivals (cultural, agricultural, ethnic etc.) in 81 provinces and 955 subprovinces of Turkey for the 2013- 2014 time period by using spatial statistics and mapping analysis. Exploratory Spatial Data Analysis (ESDA) was used to determine whether there is a spatial pattern of festivals in Turkey or not. Spatial correlation analysis which covers global and local spatial autocorrelation is conducted to determine meaningful patterns. Results shows that there is a moderate positive spatial autocorrelation, which suggests a clustered spatial pattern in the distribution of the number of festivals across Turkey. In addition, in terms of festival themes, there is no spatial autocorrelation in Turkey. In other words, festivals are randomly assigned to clusters.