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- 저자 : jamshidian-Tehrani (검색결과 2 건)
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Effect of Smoking on Retinal Thickness and Vascular Density in Thyroid Eye Disease
Mansooreh Jamshidian-Tehrani,Abolfazl Kasaei,Zahra Mahdizad,Masoud Aghsaei Fard,Mehdi Aminizade 대한안과학회 2021 Korean Journal of Ophthalmology Vol.35 No.5
Purpose: To evaluate the effect of smoking on retinal thickness and macular and peripapillary vascular density in thyroid eye disease (TED). Methods: In this cross-sectional study, subjects diagnosed with TED were analyzed in three groups: smokers, passive smokers, and non-smokers. Ganglion cell complex thickness, total retinal thickness, macular superficial vascular plexus densities, deep vascular plexus densities, optic nerve head, and radial peripapillary capillary density were measured in each group. Results: Twenty-two eyes (21.6%) of active smokers, 11 eyes (10.8%) of passive smokers, and 69 eyes (67.6%) of non-smokers constitute the study subjects. Twenty-one eyes (12.6%) had active status (clinical activity score ≥3), 77 eyes (46.1%) were neither active nor compressive, four eyes (2.4%) of two patients constituted the compressive group. Age and disease activity adjusted analysis was performed. Ganglion cell complex thickness of smokers was significantly higher than non-smokers in the inferior hemi-parafoveal sector (p = 0.04). Active smokers had significantly higher (p < 0.01) retinal thickness in all sectors compared to non-smokers, except the foveal sector. Smokers had lower superficial vessel density in the superior parafoveal sector compared to non-smokers (p = 0.04). Considering deep vessel densities between smokers and non-smokers, no significant difference was observed. Radial peripapillary capillary densities (significant difference was observed in the whole image and infranasal peripapillary sector), Macular vascular densities (significant difference was observed in parafoveal sectors), and optic nerve head (not reaching statistical significance level in any sectors) were highest in passive smokers. Conclusions: Smoking is associated with increased total retinal thickness. Macular vascular densities were not different between smokers and non-smokers in TED.
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Orbital Exenteration: A 23-year Report
abolfazl kasaee,mansooreh jamshidian-Tehrani,bahram eshraghy,kambiz ameli,shahbaz nekoozadeh,motahareh sadeghi 대한안과학회 2019 Korean Journal of Ophthalmology Vol.33 No.4
Purpose: Orbital exenteration is a psychologically and anatomically disfiguring procedure which indicated insome patients with malignant or progressive diseases of orbital and periorbital area. In this study, we reviewed176 patients that underwent orbital exenteration. Methods: This was a retrospective study of medical records from all patients who underwent orbital exenterationfrom March 1991 to March 2014 in oculoplastic department at an eye care center. Demographic data,diagnosis, site of primary involvement and technique of surgery were determined in patients. Results: One hundred seventy-six cases of orbital exenteration were included that had documented histopathology. The age of patients ranged from 1 to 91 years (mean age ± standard deviation, 55.43 ± 27 years). Ninety-seven (55.11%) males and 79 (44.88%) females were included. Fifteen different tumors were identified. Themost common indication was patients with basal cell carcinoma 49 (28%) followed by 41 (23.5%) squamouscell carcinomas, 35 (20%) retinoblastoma, and 13 (7%) adenoid cystic carcinomas. In total, adnexal malignancieswere the most common tumors, secondarily involving the orbit. Eyelids 89 (50.5%) and the globe 43 (24%)were the most frequent site of involvement. Three types of exenteration were performed, based on availabledata of 129 operation sheets, 46 (35.7%) subtotal, 62 (48.1%) total, and 21 (16.3%) cases of extensive exenterations. In total 97 cases were evaluated pathologically for perineural involvement, of which perineural invasionwas noted in 9 (7%) reports. Conclusions: Frequency of exenteration in our center has increased in past 3 years and the majority of caseswere eyelid basal cell carcinoma. Patient education considering periocular lesions can help in earlier diagnosisof malignant lesions and therefore reducing the number of exenteration.
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