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      • A Novel Crawler Based on Loginning Simulation for Weibo Social Network

        Ling Xing,Ling Jiang,Bao Peng 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.1

        With the rapid development of Weibo, which is the most popular microblog in china, more and more attention was paid to relative studies about it. With the objective of gathering precise information data from Weibo, which is the groundwork of these researches, a novel high efficient Weibo crawler (WCrawler) based on loginning simulation is designed. The priority evaluation is described to ensure the correlation between entires. MD5 is introduced to check for duplicates of URL crawled. Experiments demonstrate that the novel crawler has an efficiency and integrity of information collecting compared with API crawler. In addition, we present a summary of the data that collected from Weibo social network by WCrawler.

      • The Interaction between Sports and Tourism in the Context of Industry Convergence Research

        KANG Bao-ling(康保苓,) 세계문화관광학회 2010 Conference Proceedings Vol.11 No.0

        Industry Convergence is a booming economic phenomenon in the world. And the link become more closely between sports and tourism. There are the base ,the power and the achieve condition between them, they can fusion in the resource, product, and the market. The convergence development between sports and tourism is very important to optimizing the industrial structure, upgrading the industry level and promoting industrial transformation. “产业融合”已成全球范围内蓬勃发展的经济现象。旅游业与体育业的联系愈来愈紧 密,具备融合的基础、动力和实现条件,可在资源、产品、市场等方面互动融合。旅游业和体 育业的融合发展对优化旅游产业结构、提升产业能级、促进产业转型有着重要意义。

      • KCI등재

        Antioxidant Flavone Glycosides from the Root of Pteroxygonum giraldii

        Bao-Lin Li,Lin-Ling Jiang,Hui-Chun Wang,Zhan-Jun Yang,Xi-Quan Zhang,Hong-Mei Gu,Xian-Hua Tian 대한화학회 2009 Bulletin of the Korean Chemical Society Vol.30 No.7

        Two new flavone glycosides, giraldiin A and B, together with three known compounds, annulatin, myricetin 3-O-α-L-rhamnopyranoside and gallic acid, were isolated from the ethanol extract of the root of Pteroxygonum giraldii Damm. et Diels. The structures of giraldiin A and B are designated as 3'-(α-L-arabinopyranosyloxy)-4',5,5',7-tetrahydroxy-3-methoxyflavone and 4'-(β-D-glucopyranosyloxy)-5,5',7-trihydroxy-2',3-dimethoxyflavone, respectively,on the basis of detailed spectroscopic analyses. The free radical scavenging activity of giraldiin A was evaluated by decolouring spectrophotometry of pentamethine cyanine dye (Cy5) with Fe2+-H2O2 Fenton radical generating system. The results indicated the hydroxyl free radical scavenging activity of giraldiin A (ED50 = 23.7 nmol/mL) is higher than that of some known antioxidants such as rutin, puerarin, daidzein and 2,6-di-tertbutyl-4-methylphenol.

      • KCI등재
      • KCI등재

        Succession of the Nanoplankton Community during a Brown Tide in a Scallop Culture Area in China

        Ling Qiao,Jie Yu,Ying Li,Haobing Guo,Yu Zhen,Lingling Zhang,Tiezhu Mi,Fuchong Zhang,Zhenmin Bao 한국해양과학기술원 2019 Ocean science journal Vol.54 No.3

        Brown tides caused by Aureococcus anophagefferens have occurred frequently in the coastal waters of Qinhuangdao since 2009. The Changli coast is the area most strongly affected by the brown tides, which result in significant economic losses and serious ecological harm. To understand the effects of brown tides on nanoplankton diversity and biomass, samples were collected from May to July in 2012 at station XKK, which is approximately 0.2 nautical miles off the Changli coast. The V9 region of the 18S rDNA gene was used as a marker and was analyzed by Illumina sequencing to assess the nanoplankton diversity and biomass, and real-time fluorescence quantitative PCR was performed to analyze the temporal variations in the copy concentrations of the 18S rDNA of nanoplankton. The results showed that nanoplankton diversity, as determined by the Shannon index, decreased from May to June and increased in July. Illumina sequencing analysis revealed that the plankton community differed among the samples from May to July, and over this period, the dominant phytoplankton groups changed from pelagophytes to chlorophytes. Sufficient nutrients and low grazing pressure by zooplankton and scallops accelerated the growth of small-celled phytoplankton. A. anophagefferens was the most dominant phytoplankton species, with an 18S rDNA maximum copy concentration detected on 26 June, followed by Micromonas sp. and Bathycoccus prasinos, with maximum copy concentrations observed on 3 July. Ciliophora, Arthropoda and Cercozoa were the dominant taxa of the local zooplankton community. The Ciliophora and Arthropoda biomasses decreased, and the Cercozoa biomass increased when the copy concentration of A. anophagefferens peaked on 26 June. We suspect that A. anophagefferens had a significantly negative effect on the growth of Ciliophora and Arthropoda and could be ingested by Cercozoa to promote its proliferation. The small and low-abundance plankton that are likely missed in microscopic and clone library analyses could be detected using Illumina sequencing and qPCR, which provide an effective method for a comprehensive analysis of the plankton community.

      • KCI등재

        Structural, photoluminescent, and dielectric properties of Eu3+-doped Ba0.7Sr0.3TiO3 thin films

        Ling Liu,Ni Qin,Dinghua Bao 한국물리학회 2015 Current Applied Physics Vol.15 No.6

        Eu3+-doped Ba0.7Sr0.3TiO3 thin films were prepared by a chemical solution deposition method and characterized by X-ray diffraction, field emission scanning electron microscopy, photoluminescence and dielectric measurements. The thin films were well crystallized with a pure perovskite structure. A contraction of the unit cell was observed upon incorporation of Eu3+ ions below 2 mol%, while an expansion occurred as the Eu3+ concentration was further increased above 2 mol%, indicating that Eu3+ ions with different concentrations occupied different lattice sites. Photoluminescence spectra showed two prominent transitions of Eu3+ ions at 594 nm (5D0→7F1) and 618 nm (5D0→7F2) upon excitation at 395 nm (7F0→5L6). There existed two quenching concentrations at 2 mol% and 4 mol% due to different lattice sites of the Eu3+ ions. We also investigated the dielectric properties of the thin films. Our study suggests that Eu3+-doped Ba0.7Sr0.3TiO3 thin films have potential applications in multifunctional optoelectronic devices.

      • KCI등재

        The dopamine D1–D2DR complex in the rat spinal cord promotes neuropathic pain by increasing neuronal excitability after chronic constriction injury

        Bao Yi-Ni,Dai Wen-Ling,Fan Ji-Fa,Ma Bin,Li Shan-Shan,Zhao Wan-Li,Yu Bo-Yang,Liu Ji-Hua 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-

        Dopamine D1 receptor (D1DR) and D2 receptor (D2DR) are closely associated with pain modulation, but their exact effects on neuropathic pain and the underlying mechanisms remain to be identified. Our research revealed that intrathecal administration of D1DR and D2DR antagonists inhibited D1–D2DR complex formation and ameliorated mechanical and thermal hypersensitivity in chronic constriction injury (CCI) rats. The D1–D2DR complex was formed in the rat spinal cord, and the antinociceptive effects of D1DR and D2DR antagonists could be reversed by D1DR, D2DR, and D1–D2DR agonists. Gαq, PLC, and IP3 inhibitors also alleviated CCI-induced neuropathic pain. D1DR, D2DR, and D1–D2DR complex agonists all increased the intracellular calcium concentration in primary cultured spinal neurons, and this increase could be reversed by D1DR, D2DR antagonists and Gαq, IP3, PLC inhibitors. D1DR and D2DR antagonists significantly reduced the expression of p-PKC γ, p-CaMKII, p-CREB, and p-MAPKs. Levo -corydalmine ( l -CDL), a monomeric compound in Corydalis yanhusuo W.T. Wang, was found to obviously suppress the formation of the spinal D1–D2DR complex to alleviate neuropathic pain in CCI rats and to decrease the intracellular calcium concentration in spinal neurons. l- CDL-induced inhibition of p-PKC γ, p-MAPKs, p-CREB, and p-CaMKII was also reversed by D1DR, D2DR, and D1–D2DR complex agonists. In conclusion, these results indicate that D1DR and D2DR form a complex and in turn couple with the Gαq protein to increase neuronal excitability via PKC γ, CaMKII, MAPK, and CREB signaling in the spinal cords of CCI rats; thus, they may serve as potential drug targets for neuropathic pain therapy.

      • Research of Shanghai Cruise Industry Chain Distribution of Benefits

        Ling Sun,Li Tang,Xiao-di Bao,Wei Liu 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.10

        Based on the Shanghai cruise industry research, this cruise industry chain has problems with balance. Game theory was used and imbalance mainly due to lack of shipbuilding enterprises and proprietary cruises, and also because foreign cruise companies dominate Shanghai cruise industry chain. Learning from the successful experience of foreign cruise homeports’ development, the paper considers transferring the chain’s dominant right to the port enterprise gradually. Using Shapley Model to solve benefits distribution of cruise industry chain dominated by port companies. The profits distribution ratio of cruise companies, port companies and service supporting enterprises is13/48:47/96:23/96. Nash Model was also used to study the benefits distribution of industry chain whose member companies are equal. Modeling results show that Shapley Model corresponds with the requirements of benefit maximization. Finally, a validation analysis was done and proved that only the cruise industry chain leaded by homeport that can maximize the economic benefits.

      • Polymorphisms of TERT and CLPTM1L and the Risk of Hepatocellular Carcinoma in Chinese Males

        Su, Ling-Yan,Li, Xue-Lian,Shen, Li,Zhang, Yue,Zhao, Meng-Meng,Yin, Zhi-Hua,Su, Hong-Ying,Zhou, Bao-Sen Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19

        Background: Telomerase reverse transcriptase (TERT) and cleft lip and palate trans-membrane 1 like (CLPTM1L) genes located on chromosome 5p15.33 are known to influence the susceptibility to various cancers. Here, we examined the association of TERT and CLPTM1L single nucleotide polymorphisms (SNPs) with hepatocellular carcinoma (HCC). Materials and Methods: Genotyping of TERT SNP rs2736098 and CLPTM1L SNP rs401681 was performed using TaqMan allelic discrimination assays in a case-control study of 201 HCC cases and 210 controls in a Chinese male population. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using logistic regression analyses. Results: Both the rs2736098 T allele of TERT and the rs401681 T allele of CLPTM1L were associated with a significantly increased risk of HCC (adjusted odds ratio [OR]=1.605, 95% confidence interval [CI]=1.164-2.213; adjusted OR=1.399, 95%CI=1.002-1.955, respectively). Individuals carrying both TERT and CLPTM1L risk genotypes had an even higher risk of HCC (adjusted OR=4.420, 95%CI= 2.319-8.425). The TERT rs2736098 T allele was also significantly associated with the level of the HCC clinical indicator alpha-fetoprotein (P=0.026). Conclusions: Our results show that genetic variants of TERT and CLPTM1L may contribute to HCC susceptibility in Chinese males.

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