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      • KCI등재

        Mitochondrial DNA Diversification and Phylogeny among Subspecies of Chukar Partridge (Alectoris chukar), Phasianidae

        Zu Hao Huang,Nai Fa Liu,Li Xun Zhang,Yi An Xiao,Jin Long 한국유전학회 2008 Genes & Genomics Vol.30 No.3

        The taxonomic status of the subspecies Alectoris chukar remains unclear since 1830. To obtain more information on phylogenetic relationships within the species, the entire mitochondrial DNA (mtDNA) control-region sequences of eleven subspecies were analyzed to construct the phylogenetic tree among the subspecies of chukar partridge. There was a significant genetic differentiation among the subspecies with little gene flow. The phylogenetic tree grouped all the eleven subspecies into a monophyletic cluster, which included two deeply divergent phylogroups. Haplotype network was observed within A. chukar, and gene flow estimates suggest isolation among the subspecies. Our data confirmed a locality of origin (central Asia) for chukar partridge, and have clarified the relationships among the subspecies. A conventional calibration of mtDNA sequence divergence indicated an early to middle Pleistocene evolution of the main clades in A. chukar, which could have diversified in allopatry in the lowland of continental Asia. Cyclic changes in Pleistocene climate and landscape might result in subspecific divergence of chukar partridge.

      • KCI등재

        Microwave-assisted Solvent-free Synthesis of Some Dimethine Cyanine Dyes, Spectral Properties and TD-DFT/PCM Calculations

        Xiang-Han Zhang,Lan-Ying Wang*,Gao-Hong Zhai,Zhen-Yi Wen,Zu-Xun Zhang 대한화학회 2007 Bulletin of the Korean Chemical Society Vol.28 No.12

        A series of dimethine cyanine dyes were synthesized in a fast, efficient and high yield by the condensation of quaternary salts with 1H-indole-3-carbaldehyde in the presence of piperidine under solvent-free microwave irradiation. The products were identified by 1H NMR, IR, UV-Vis spectra and elemental analysis. The absorption and fluorescence properties of these dyes were investigated both experimentally and theoretically. Calculations performed at a combination of time-dependent density functional theory (TD-DFT) and the polarizable continuum model (PCM) reproduced the p-p* type absorption bands of the dyes. Regression analysis was used for studying theoretical results of the absorption maxima in different solvents. Compared with experimental counterparts, estimated overall uncertainties in the absorption maxima were about ?2%.

      • Depression and the Risk of Breast Cancer: A Meta-Analysis of Cohort Studies

        Sun, Hui-Lian,Dong, Xiao-Xin,Cong, Ying-Jie,Gan, Yong,Deng, Jian,Cao, Shi-Yi,Lu, Zu-Xun Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8

        Background: Whether depression causes increased risk of the development of breast cancer has long been debated. We conducted an updated meta-analysis of cohort studies to assess the association between depression and risk of breast cancer. Materials and Methods: Relevant literature was searched from Medline, Embase, Web of Science (up to April 2014) as well as manual searches of reference lists of selected publications. Cohort studies on the association between depression and breast cancer were included. Data abstraction and quality assessment were conducted independently by two authors. Random-effect model was used to compute the pooled risk estimate. Visual inspection of a funnel plot, Begg rank correlation test and Egger linear regression test were used to evaluate the publication bias. Results: We identified eleven cohort studies (182,241 participants, 2,353 cases) with a follow-up duration ranging from 5 to 38 years. The pooled adjusted RR was 1.13(95% CI: 0.94 to 1.36; $I^2=67.2%$, p=0.001). The association between the risk of breast cancer and depression was consistent across subgroups. Visual inspection of funnel plot and Begg's and Egger's tests indicated no evidence of publication bias. Regarding limitations, a one-time assessment of depression with no measure of duration weakens the test of hypothesis. In addition, 8 different scales were used for the measurement of depression, potentially adding to the multiple conceptual problems concerned with the definition of depression. Conclusions: Available epidemiological evidence is insufficient to support a positive association between depression and breast cancer.

      • SCOPUSKCI등재

        Microwave-assisted Solvent-free Synthesis of Some Dimethine Cyanine Dyes, Spectral Properties and TD-DFT/PCM Calculations

        Zhang, Xiang-Han,Wang, Lan-Ying,Zhai, Gao-Hong,Wen, Zhen-Yi,Zhang, Zu-Xun Korean Chemical Society 2007 Bulletin of the Korean Chemical Society Vol.28 No.12

        A series of dimethine cyanine dyes were synthesized in a fast, efficient and high yield by the condensation of quaternary salts with 1H-indole-3-carbaldehyde in the presence of piperidine under solvent-free microwave irradiation. The products were identified by 1H NMR, IR, UV-Vis spectra and elemental analysis. The absorption and fluorescence properties of these dyes were investigated both experimentally and theoretically. Calculations performed at a combination of time-dependent density functional theory (TD-DFT) and the polarizable continuum model (PCM) reproduced the π-π* type absorption bands of the dyes. Regression analysis was used for studying theoretical results of the absorption maxima in different solvents. Compared with experimental counterparts, estimated overall uncertainties in the absorption maxima were about ±2%.

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