Explore the Secrecy in the Distribution of Red and Yellow Soil on the Earth

Zhongjie Ye,Liqun Xu 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Enhancing Electrocatalytic Production of H2O2 by Modulating Coordination Environment of Cobalt Center

Guoling Wu,Zhongjie Yang,Tianlin Zhang,Yali Sun,Chang Long,Yaru Song,Shengbin Lei,Zhiyong Tang 대한화학회 2021 Bulletin of the Korean Chemical Society Vol.42 No.8

As an environmentally friendly oxidant, H2O2 is widely utilized in various fields; however, its production methods remain limited to the chemical anthraquinone process. Alternatively, electrocatalytic oxygen reduction possesses numerous notable advantages (e.g., cost-effectiveness, small-scale, and distributed nature). As electrocatalytic oxygen reduction has been widely investigated in the fields of fuel cells and metal-air batteries, the mechanism of the 2e?-ORR pathway for producing H2O2 is not sufficiently clear. Herein, we explore the effect of the cobalt (Co) coordination environment on the electrochemical production of H2O2. The detailed investigation on N-, P-, and S-coordinated Co catalysts (Co1N1N3, Co1P1N3, and Co1S1N3) demonstrates that changing the coordination environment evidently affects the H2O2 selectivity, and the S-coordinated Co exhibits the best catalytic performance. This finding would lead to the design and selection of catalysts at atomic level for producing H2O2 via electrocatalytic oxygen reduction.

A new strategy for stem cells therapy for erectile dysfunction: Adipose-derived stem cells transfect Neuregulin-1 gene through superparamagnetic iron oxide nanoparticles

Jianxing Cheng,Zhongjie Zheng,Wenhao Tang,Jichun Shao,Hui Jiang,Haocheng Lin 대한비뇨의학회 2022 Investigative and Clinical Urology Vol.63 No.3

Purpose: Our previous studies showed that nanotechnology improves derived adipose-derived stem cells (ADSCs) therapy for erectile dysfunction (ED). In this study, the Neuregulin-1(NRG1) gene was transfected into ADSCs with superparamagnetic iron oxide nanoparticles (SPION) further to improve the therapeutic effect of ADSCs on ED. Materials and Methods: ADSCs were isolated from epididymal adipose tissue of Sprague–Dawley rats. The optimal concentration of PEI-SPION (SPION modified with polyethyleneimine) was selected to construct the gene complex. After electrostatic binding of PEI-SPION and DNA, a PEI layer was wrapped to make the PEI-SPION-NRG1-PEI gene transfection complex. Different groups were set up for transfection tests. Lipo2000 transfection reagent was used as the control. PEI-SPION-NRG1-PEI in the experimental group was transfected under an external magnetic field. Results: When the concentration of PEI-SPION was 10 µg/mL, it had little cytotoxicity, and cell activity was not significantly affected. PEI-SPION-NRG1-PEI forms positively charged nanocomposites with a particle size of 72.6±14.9 nm when N/P ≥8. The PEI-SPION-NRG1-PEI gene complex can significantly improve the transfection efficiency of ADSCs, reaching 26.74%±4.62%, under the action of the external magnetic field. PCR and Western blot showed that the expression level of the NRG1 gene increased significantly, which proved that the transfection was effective. Conclusions: PEI-SPION can be used as a vector for NRG1 gene transfection into ADSCs. PEI-SPION-NRG1-PEI packaging has the highest transfection efficiency under the external magnetic field than the other groups. These findings may provide a new strategy for ADSCs therapy for ED.

ONLINE MEASURING METHOD FOR THE ENGINES’ IVC TIMING BASED ON THE IN-CYLINDER PRESSURE FLUCTUATION

Fushui Liu,Zhongjie Shi,Yikai Li,Yang Hua,Yanlin Chen,Yongli Gao 한국자동차공학회 2019 International journal of automotive technology Vol.20 No.2

The in-cylinder pressure fluctuations caused by intake valve closure (IVC) event were first investigated experimentally based on a single cylinder diesel engine with different cams. The experimental results show that the occurrence of the in-cylinder pressure fluctuation during the compression stroke has a close correlation with the IVC event. The start time of the pressure oscillation advances as the IVC timing advances. With a fixed IVC timing, higher engine speed results in a larger fluctuation amplitude and a longer fluctuation duration. To explain these phenomena, a numerical simulation model has been adopted. Results show that the IVC event causes pressure oscillations in both the cylinder and intake runner. At the same engine speed, the amplitude of the pressure oscillation decreases first and then increases as the IVC retards due to the change of gas flow direction. With the same intake temperature, the absolute time delay keeps constant at different engine speeds and IVC timings. The absolute time delay decreases as the intake temperature decreases. Based on the conclusions above, the potential methods to use the pressure oscillation are also discussed. An innovative engine valve timing detection method on the basis of in-cylinder pressure oscillation is presented.

Hsa_circ_0129047 sponges miR-665 to attenuate lung adenocarcinoma progression by upregulating protein tyrosine phosphatase receptor type B

Xiaofan Xia,Jinxiu Fan,Zhongjie Fan 대한약리학회 2023 The Korean Journal of Physiology & Pharmacology Vol.27 No.2

Compelling evidence has demonstrated the critical role of circular RNAs (circRNAs) during lung adenocarcinoma (LUAD) progression. Herein, we explored a novel circRNA, circ_0129047, and detailed its mechanism of action. The expression of circ 0129047, microRNA-665 (miR-665), and protein tyrosine phosphatase receptor type B (PTPRB) in LUAD tissues and cells was determined using reverse transcription quantitative polymerase chain reaction and Western blotting. Cell Counting Kit- 8 and colony formation assays were conducted to detect LUAD cell proliferation, and western blotting was performed to quantify apoptosis-related proteins (Bcl- 2 and Bax). Luciferase reporter and RNA immunoprecipitation assays were used to validate the predicted interaction between miR-665 and circ_0129047 or PTPRB. A xenograft assay was used for the in vivo experiments. Circ_0129047 and PTPRB were downregulated in LUAD tissues and cells, whereas miR-665 expression was upregulated. Overexpression of circ_0129047 suppresses LUAD growth in vivo and in vitro. Circ_0129047 is the target of miR-665, and the miR-665 mimic ablated the antiproliferative and pro-apoptotic phenotypes of LUAD cells by circ_0129047 augmentation. MiR-665 targets the 3ʹUTR of PTPRB and downregulates PTPRB expression. PTPRB overexpression offsets the pro-proliferative potential of miR-665 in LUAD cells. Circ_0129047 sequestered miR-665 and upregulated PTPRB expression, thereby reducing LUAD progression, suggesting a promising approach for preventing LUAD.

Influences of Wire Diameters on Output Power in Electromagnetic Energy Harvester

Yan Peng,Lan Zhang,Zhongjie Li,Songyi Zhong,Yong Liu,Shaorong Xie,Jun Luo 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.10 No.1

In this paper, we systematically investigate how the wire diameter affects the output performance of electromagnetic energy harvesters. The harvesters with the same structure but different coils mainly comprised of a magnet array, two coil arrays, a pair of springs and a housing. Different discrete wire diameters of coils are selected to compare the output performance and explore the optimal value. We first set up the theoretical model of the configuration to predict optimal wire diameter and conduct simulations to observe open-circuit voltage and output power, and find the hypothetically optimal diameter leading to the best performance. Subsequently, we fabricate a series of prototypes and conduct four groups of experiments from the following aspects for comparison purposes: constant frequency excitation, frequency sweep, impedance matching and charging capacitors, and validate the theoretically estimated value. When we operate the prototypes under the excitation of 20 Hz, 1.0 g, the maximum average power of 37.45 mW is generated with the best wire diameter, at least 1.62 times as high as that in other cases. The results of capacitor charging experiments, i.e., charging rate, further validate the output power trend. This study can be of great significance for power density improvement in electromagnetic energy harvesters.

A Robust and Accurate Traveltime Calculation from Frequency-domain Two-way Wave-equation Modeling Algorithm

Qin, Yilong,Zhang, Zhongjie,Shin, Changsoo,Ko, Seungwon,Seo, Youngtak,Han, Uk,Chen, Yun 한국암반공학회 2004 Geosystem engineering Vol.7 No.1

We improve the accuracy and stability of traveltime calculation method using frequency-domain modeling algorithm. We perform a parameter analysis to obtain the optimum combination of frequency and damping factor and thus improve the accuracy of traveltime. Then we obtain the empirical formula for our numerical algorithm. Lastly, we propose the adaptive frequency and the adaptive damping factor for an inhomogeneous model to eliminate the distortion in the traveltime contour. Two-dimensional numerical examples verify that the proposed algorithm gives a much smaller traveltime error and a better traveltime contour for the complex model. Compared to the other two methods, this algorithm computes traveltime that is close to a directly transmitted wave. We demonstrated our algorithm on 2D IFP Marmousi models, and the numerical results show that our algorithm is a faster traveltime calculation method of a directly transmitted wave for imaging the subsurface and transmission tomography.

Therapeutic responses to chemotherapy or immunotherapy by molecular subtype in bladder cancer patients: A meta-analysis and systematic review

Shunde Wang,Xiaoyu Yuan,Zhongjie Shen,Jiaming Zhao,Baishu Zheng,Junyong Zhang,Chengguo Ge 대한비뇨의학회 2023 Investigative and Clinical Urology Vol.64 No.3

To systematically evaluate the differences in therapeutic response to chemotherapy or immunotherapy between different molecular subtypes of bladder cancer (BC). A comprehensive literature search was performed up to December 2021. Consensus clusters 1 (CC1), CC2 and CC3 molecular subtypes were used to perform meta-analysis. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the therapeutic response by fix-effect modeling. Eight studies involving 1,463 patients were included. For immunotherapy, CC3 showed the highest response rate (CC1 vs. CC3: OR=0.52, 95% CI=0.34–0.78, p=0.002; CC2 vs. CC3: OR=0.42, 95% CI=0.28-0.62, p<0.001), which was mainly reflected in the highest response rate to atezolizumab (CC1 vs. CC3: OR=0.47, 95% CI=0.29–0.75, p=0.002; CC2 vs. CC3: OR=0.38, 95% CI=0.24–0.59, p<0.001). For chemotherapy, CC3 had the lowest response rate to the overall chemotherapy (CC1 vs. CC3: OR=2.05, 95% CI=1.23–3.41, p=0.006; CC2 vs. CC3: OR=2.48, 95% CI=1.50–4.10, p<0.001). Compared with CC2, CC3 responded poorly to both neo-adjuvant chemotherapy (NAC) (OR=1.93, 95% CI=1.09–3.41, p=0.020) and chemoradiation therapy (CRT) (OR=6.07, 95% CI=1.87–19.71, p<0.001). Compared with CC1, CC3 only showed a poorer response to CRT (OR=4.53, 95% CI=1.26–16.27, p=0.020), and no difference in NAC. Our study suggested that molecular classifications are important predictors of cancer treatment outcomes of BC patients and could identify subgroup patients who are most likely to benefit from specific cancer treatments.

ENHANCED VISIBLE-LIGHT-DRIVEN PHOTOCATALYTIC DEGRADATION PERFORMANCE OF CIP ON BiVO 4 – Bi 2 WO 6 NANO-HETEROJUNCTION PHOTOCATALYSTS

SHAOFANG SUN,WEISHENG GUAN,XIAN ZHANG,ZHONGJIE ZHANG,YAN YAN 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.2

The removal of CIP from the environment has become a mandatory issue. In our paper, we haverealized the visible-light-driven degradation of CIP on the BiVO 4 – Bi 2 WO 6 nano-heterojunctionphotocatalysts. The synthesized photocatalysts were characterized by X-ray difraction (XRD),¯eld emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM),high-resolution transmission electron microscopy (HRTEM), ultraviolet-visible (UV-Vis) ab-sorption spectra and photoluminescence (PL) spectra. Compared with the single-phase BiVO 4and Bi 2 WO 6 counterparts, BiVO 4 – Bi 2 WO 6 nano-heterojunction photocatalysts show enhancedphotocatalytic degradation activities in visible-light-driven CIP degradation. Particularly, whenRðBi 2 WO 6 =BiVO 4 Þ ¼ 10 wt:% , the products exhibit the highest CIP degradation ratio in 60 min of76.8% under visible light illumination. The tentative mechanism of the interface charge transfer(IFCT) efect in the BiVO 4 – Bi 2 WO 6 heterojunction structure is also discussed by using the bandposition calculation.

Essential oil of Citrus limon Osbeck: An insecticidal natural product against Cryptolestes pusillus SchÖnherr

Jie Yu,Shi Tianyu,Yang Dong,Zhang Zhongjie 한국응용곤충학회 2024 Journal of Asia-Pacific Entomology Vol.27 No.1

This study investigated the insecticidal activity and mechanism of action of essential oil from Citrus limon Osbeck (C. limon oil). The fumigation method was used to determine the insecticidal activity of different concentrations of C. limon oil against adult Cryptolestes pusillus (C. pusillus). In addition, the effect of C. limon oil on the organs of adult C. pusillus was studied. The results showed that when the concentration of C. limon oil reached 0.6 μL/cm 3 , following fumigation for 4, 8, 12, 16, 20, and 24 h, the corrected mortality rates of adult C. pusillus were 13 %, 30 %, 47 %, 95 %, 97 %, and 100 %, respectively. Furthermore, C. limon oil caused vacuolization in the digestive tract and adipose cells, thus, as a plant-based insecticide, it has strong research and application value.