International Joint Ventures and Endogenous Protection: A Political-Economy Approach

( Lai Xun Zhao ) 세종대학교 경제통합연구소 (구 세종대학교 국제경제연구소) 1997 Journal of Economic Integration Vol.12 No.4

This paper constructs a model of international joint ventures (JVs) with political-economy considerations as the main motivation. A foreign firm decides whether to undertake full ownership foreign direct investment (FDI), or to form a JV with a home firm, while the home firm lobbies against FDI. It is shown that the level of lobbying is lower in the JV regime than in the FDI regime if the foreign firm transfer sufficiently advanced technology to the home firm through the JV. However, if the foreign firm anticipates future protectionist threats and forms a JV with the home firm beforehand (quid pro quo JV), then the foreign firm`s profit increases and the home firm`s level of lobbying decreases. (JEL Classification: F21, F12)

Error Analysis of Heat Flux Measurement on Membrane Waterwalls

Zhao Hong Fang,Dong Lai Xie,Nairen Diao 대한기계학회 1998 Heat transter conference Vol.4 No.1

Comparative digestibility of nutrients and amino acids in high-fiber diets fed to crossbred barrows of Duroc boars crossed with Berkshire×Jiaxing and Landrace×Yorkshire

Zhao, Jinbiao,Wang, Qiuyun,Liu, Ling,Chen, Yiqiang,Jin, Aiming,Liu, Guoliang,Li, Kaizhen,Li, Defa,Lai, Changhua Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.5

Objective: This experiment was conducted to determine the differences in the apparent ileal (AID) and total tract digestibility (ATTD) of nutrients and indispensable amino acids (IAA) in high-fiber diets with wheat middlings, rice bran or alfalfa meal fed to Duroc${\times}$(Landrace${\times}$Yorkshire) (DLY) and Duroc${\times}$ (Berkshire${\times}$Jiaxing) (DBJ) growing barrows. Methods: Eighteen DLY and 18 DBJ growing barrows were randomly allotted to a $2{\times}3$ factorial arrangement involving 2 crossbreeds and 3 high-fiber diets. The experiment lasted 15 d with 10 d for diets adaptation, 3 d for feces collection and 2 d for digesta collection. Three diets were based on corn and soybean meal with 25% wheat middlings, rice bran and alfalfa meal respectively. Results: DBJ had a greater (p<0.05) AID of isoleucine, leucine, lysine, phenylalanine and valine and a lower (p<0.05) AID of methionine than DLY. The hindgut disappearance of acid detergent fiber for DBJ was greater (p<0.05) than DLY. The ATTD of gross energy, dry matter, organic matter, neutral detergent fiber and acid detergent fiber in wheat middlings diet were greater (p<0.05) than in rice bran and alfalfa meal diets. The hindgut disappearance of neutral detergent fiber and acid detergent fiber in wheat middlings diet or rice bran diet were the highest or lowest (p<0.05), and those of alfalfa meal diet were the middle. Barrows fed rice bran diet had a greater (p<0.05) hindgut disappearance of gross energy, dry matter and organic matter and lower hindgut disappearance of neutral detergent fiber and acid detergent fiber than barrows fed alfalfa meal diet Conclusion: DBJ growing barrows showed a significant higher digestibility of fiber in the hindgut and most IAA in the small intestine compared with DLY barrows. The digestibilities of chemical constituents and IAA were affected by the diets formulated with different fiber sources.

Dynamic modeling, sensitivity assessment, and design of VSC-based microgrids with composite loads

Zhao, Zhuoli,Yang, Ping,Bottrell, Nathaniel,Lai, Loi Lei,Green, Timothy C. The Korean Institute of Power Electronics 2020 JOURNAL OF POWER ELECTRONICS Vol.20 No.1

Microgrids are seen as useful for increasing the flexibility of distribution networks and integrating large amounts of distributed generations. Ensuring the dynamic stability of power converter-dominated microgrids that is robust to a range of load conditions is a significant challenge and essential for ensuring reliability. Induction motor (IM) loads are widespread and have substantial impacts on the dynamic behavior and stability characteristics of low-inertia microgrids. The stability assessment and design of microgrids considering composite loads have not been sufficiently addressed in the current literature, where static loads are commonly used to simplify the modeling and analysis. In this paper, the dynamic stability of voltage source converter-based microgrids is investigated, considering composite loads as dynamic element. A complete state-space model of the microgrid with both IM load and static load is developed. Participation factor analysis is conducted to identify the contribution of the composite loads to the dominant oscillatory modes of the microgrid. Furthermore, sensitivity assessment of the dominant eigenvalues is presented to further identify the appropriate ranges of variations in the control parameters, operating conditions and operating points of the microgrid. It is shown that composite loads in a realistic microgrid significantly affect the dominant oscillatory modes and, consequently, the system stability margin. Ignoring the composite load dynamics in microgrid stability studies may lead to misleading analytical results. Simulations based on MATLAB/Simulink and experimental tests based on a laboratory prototype microgrid are implemented to demonstrate the theoretical analysis.

Satellite-indicated variations in China’s forests from 2001 to 2009

Lai Jiang,Jingyun Fang,Daojing Zhou,Xia Zhao 한국산림과학회 2012 Forest Science And Technology Vol.8 No.2

Variations of forest area and vegetation activity in China from 2001 to 2009 were investigated using the IGBP landcover data and the EVI (Enhanced Vegetation Index) dataset derived from Moderate-Resolution Imaging Spectroradiometer (MODIS) products in the 3 years of 2001, 2005, and 2009. The area of forests in China had increased by about 10%, and the changes in EVI-indicated vegetation activity showed large regional differences. The EVI decreased between 2001 and 2005 while it increased between 2005 and 2009 in most areas of southern China. It also indicated seasonal differences in different periods: an increase in fall between 2001 and 2005 and in spring between 2005 and 2009.

Micellization behavior of binary mixtures of amino sulfonate amphoteric surfactant with different octylphenol polyoxyethylene ethers in aqueous salt solution: Both cationic and hydrophilic effects

Zhao Hua Ren,Jing Huang,Yue Luo,Yan Cheng Zheng,Ping Mei,Lu Lai,Yan Ling Chang 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.36 No.-

The effect of different valent inorganic cations and the hydrophilic group of surfactant on themicellization behavior of binary surfactant mixtures constituted by an amphoteric surfactant, sodium3-(N-dodecyl ethylenediamino)-2-hydropropyl sulfonate (C12AS), and three nonionic surfactantsoctylphenol polyoxyethylene ether (OP-n) with different numbers of oxyethylene glycol ethers (n),namely, OP-10, OP-7, and OP-4 was investigated in aqueous solution. These inorganic cations includeNa+, K+, Mg2+, Ca2+, Ba2+, Al3+ and Fe3+. Both the tensiometry and the UV–vis spectrophotometry usingpyrene as a probe were adopted to determine the critical micelle concentrations (cmc) of individual ormixed surfactants. Interaction parameters between two surfactants and other parameters were obtainedbased on the regular solution theory, the pseudophase separation model, Rubingh’s model, etc. Thermodynamic parameters including Gibbs energy of micellization and thermodynamic stability werealso calculated by both the equation proposed by Molyneux et al. and Maeda’s treatment, respectively. The effect of different valent cations on both the mixed cmc of surfactant mixtures and the molar fractionof C12AS in mixed micelle (X1) can be explained theoretically by the salting-out effect, electrostaticinteraction and steric effect. For three binary surfactant mixtures, the chain length of hydrophilic groupof surfactant results in different micellization behaviors. On adding salts, the interaction parametersshow that there exists a synergistic effect between two surfactants, and the effect increases withincreasing the ratio of valence (Z) and atom radius (R) of cation, especially, for the C12AS/OP-4 mixture. With increasing the Z/R value of cation, a deviation of X1 from the ideal value shows a divergence forthree binary surfactant mixtures because of different hydrophilicities of surfactant. Thermodynamicparameters indicate that the addition of cations with a large Z/R value can be contributive moreeffectively to the formation of stable mixed micelle than the case in the presence of cations with a smallZ/R value.

3D-quantitative structure–activity relationship and antiviral effects of curcumin derivatives as potent inhibitors of infl uenza H1N1 neuraminidase

Yanni Lai,Yiwen Yan,Shanghui Liao,Yun Li,Yi Ye,Ni Liu,Fang Zhao,Peiping Xu 대한약학회 2020 Archives of Pharmacal Research Vol.43 No.5

Curcumin derivatives have been shown to inhibitreplication of human infl uenza A viruses (IAVs). However, itis not clear whether curcumin and its derivatives can inhibitneuraminidase (NA) of influenza virus. In this study, ameaningful 3D quantitative structure–activity relationshipmodel (comparative molecular fi eld analysis R 2 = 0.997,q 2 = 0.527, s = 0.064, F = 282.663) was built to understandthe chemical–biological interactions between their activitiesand neuraminidase. Molecular docking was used to predictbinding models between curcumin derivatives and neuraminidase. Real-time polymerase chain reactions showed thatthe fi ve active curcumin derivatives might have direct eff ectson viral particle infectivity in H1N1-infected lung epithelial(MDCK) cells. Neuraminidase activation assay showed thatfi ve active curcumin derivatives decreased H1N1-inducedneuraminidase activation in MDCK cells. Indirect immunofluorescence assay indicated that two active curcuminderivatives (tetramethylcurcumin and curcumin) down-regulatedthe nucleoprotein expression. Curcumin inhibited IAVin vivo. The therapeutic mechanism of curcumin in the treatmentof infl uenza viral pneumonia is related to improvingthe immune function of infected mice and regulating secretionof tumor necrosis-α, interleukin-6, and interferon-γ. These results indicate that curcumin derivatives inhibit IAVby blocking neuraminidase in the cellular model and curcuminalso has anti-IAV activity in the animal model.

A Study on the Formation Mechanism and Calculation Method of Surrounding Rock Pressure in Shallow-buried Loess Tunnel Considering the Influence of Vertical Joints

Mingkun Zhao,Hongpeng Lai,Yuyang Liu 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.4

Vertical joints have significant effects on the stability of shallow-buried loess tunnel. Due to the presence of vertical joints distributed widely in loess, the formation mechanisms of surrounding rock pressure on shallow-buried loess tunnel and its computational method are far different from those in other types of soil tunnel. In this study, the distribution characteristics of surrounding rock pressure in shallow-buried loess tunnel were investigated, and discrete element software 3DEC was used to analyze the formation mechanism and development process of surrounding rock pressure in loess tunnel under the influence of joints. We correlated the stratum deformation characteristic with the frictional force caused by the mutual dislocation between joints, and revised the semi-empirical method (Chinese Code methods) in China. The results show that the measured data of radial surrounding rock pressure of shallow-buried loess tunnel are generally between 0 − 600 kPa, and 80% in the range of 0 − 200 kPa. The surrounding rock pressure increases with the burial depth, while the distribution of lateral pressure coefficient is relatively discrete. The existence of loess vertical joints (LVJs) aggravates the uneven distribution of the vertical pressure above the tunnel, and the reduction of the lateral earth pressure coefficient at rest under the influence of joints leads to an increase in pressure near the arch shoulder, these two constitute the essence of the joints action on the surrounding rock pressure. The surrounding rock pressure of the shallow-buried loess tunnel reaches the peak stress at about 0.5D from the tunnel face (D is the tunnel span), which is about 1.04 − 1.32 times of the initial stress. After the excavation of the upper step, the stress of the tunnel crown monitoring point decreased to about 60% of the initial stress. Compared with ignoring the influence of joints, the time of reaching the peak stress at the arch shoulder monitoring point is earlier, and the final stress release degree is smaller. The comparison of the analytical results (proposed method) with the numerical results and the field data exhibits good agreement, proving the proposed method's correctness.

Research on Development Strategies of Preschool Teachers’ Practical Knowledge in Web 2.0 Era

Yu Lai,Guijie Li,Xin Zhao,Dan Li 보안공학연구지원센터 2014 International Journal of Multimedia and Ubiquitous Vol.9 No.3

Safety and Efficacy of Elbasvir/Grazoprevir in Asian Participants with Hepatitis C Virus Genotypes 1 and 4 Infection

( Wei Lai ),( Hiromitsu Kumada ),( Ponni Perumalswami ),( Tawesak Tanwandee ),( Wendy Cheng ),( Jeong Heo ),( Pin Nan Cheng ),( Peggy Hwang ),( Sheng Mei Mu ),( Xu Min Zhao ),( Michael Robertson ),( B 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: Clinical experience with direct-acting antiviral treatments for hepatitis C virus (HCV) infection is emerging in the Asia-Pacific region. We conducted an integrated analysis of the safety and efficacy of elbasvir (EBR)/grazoprevir (GZR) in self-identified Asian participants who were enrolled in 11 EBR/GZR phase 2/3 studies. Methods: All participants received EBR/GZR 50 mg/100 mg alone for 12 weeks or in combination with ribavirin (RBV) for 16 weeks. The primary endpoint of all studies was sustained virologic response (HCV RNA < 15 IU/mL) 12 weeks after end of therapy (SVR12). Results: A total of 780 Asian participants with HCV GT1 or 4 infection were included (GT1b, n=715; GT1non-b, n=63; GT4, n=2). Most participants were enrolled from Japan (n=366, 46.9%), mainland China (n=146, 18.7%), Taiwan (n=109, 14.0%) and South Korea (n=90, 11.5%). Overall, 12.4% of participants had cirrhosis, and 20.4% were treatment-experienced. SVR12 was achieved by 756/780 (96.9%, 95% CI 95.5-98.0) of all Asian participants, including 748/772 (96.9%, 95% CI 95.4- 98.0) who received EBR/GZR for 12 weeks and 8/8 (100%, 95% CI 63.1-100.0) who received EBR/GZR + RBV for 16 weeks. The frequency of safety events among Asian participants was: any adverse event (AE), 58.1% (453/780), drug-related AEs, 23.6% (184/780), serious AEs, 2.6% (20/780), and discontinuation due to an AE, 0.9% (7/780). Fifteen participants (1.9%) had elevated ALT/AST levels that met the criteria for an event of clinical interest (ALT/AST >3× baseline and >100 U/L), 3 of whom discontinued treatment. The efficacy and safety profile of EBR/GZR was comparable to that observed among non-Asians. Conclusions: The combination of EBR/GZR was safe and highly effective in this large population of Asian participants with primarily HCV GT1b infection. Late transaminase elevations were reported in approximately 2% of participants, which is consistent with the safety profile of EBR/GZR in non-Asians.