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YuKyeong Cho,Min-Ji Kim,Sung-Koo Kim 한국생물공학회 2013 KSBB Journal Vol.28 No.6
Ethanol productions were performed by separate hydrolysis and fermentation (SHF) and simultaneous saccharification and fermentation (SSF) processes using seaweed, Enteromorpha intestinalis (sea lettuce). Pretreatment conditions were optimized by the performing thermal acid hydrolysis and enzymatic hydrolysis for the increase of ethanol yield. The pretreatment by thermal acid hydrolysis was carried out with different sulfuric acid concentrations in the range of 25 mM to 75 mM H₂SO₄, pretreatment time from 30 to 90 minutes and solid contents of seaweed powder in the range of 10~ 16% (w/v). Optimal pretreatment conditions were determined as 75 mM H₂SO₄ and 13% (w/v) slurry at 121℃ for 60 min. For the further saccharification, enzymatic hydrolysis was performed by the addition of commercial enzymes, Celluclast 1.5 L and Viscozyme L, after the neutralization. A maximum reducing sugar concentration of 40.4 g/L was obtained with 73% of theoretical yield from total carbohydrate. The ethanol concentration of 8.6 g/L of SHF process and 7.6 g/L of SSF process were obtained by the yeast, Saccharomyces cerevisiae KCTC 1126, with the inoculation cell density of 0.2 g dcw/L.
Yukyeong Jung,Jae Ho Han,Seokyu Choi,Jae Hee Lee 한국청각언어재활학회 2021 Audiology and Speech Research Vol.17 No.4
Purpose: This study aimed to measure the test-retest reliability of the Korean Matrix sentence-in-noise test in a sound-field testing condition. Methods: Fifty-five listeners with normal hearing participated. The sound-field speech-in-noise test was administered with a front loudspeaker by presenting noise at a fixed level (65 dB SPL) while adaptively adjusting the sentence level based on the listener’s response. The speech reception thresholds (SRTs) corresponding to 50% sentence-in-noise intelligibility were obtained using speech-shaped noise (SSN), International Collegium of Rehabilitative Audiology (ICRA) noise, and International Speech Test Signal (ISTS) noise. For the test-retest reliability, each subject was tested twice in a 2-week interval. The test-retest reliabilities were judged by the intraclass correlation coefficient (ICC), the minimal detectable change (MDC) values, and Bland-Altman plots. Results: The test-retest reliabilities of the Korean Matrix sentence test were good (ICC, 0.84~0.86) across SSN, ICRA, ISTS noises. The MDC was 0.92 dB SNR for SSN and 2.83 and 2.98 dB SNR for ICRA and ISTS, indicating the random measurement error varied across the types of noise. Conclusion: The Korean Matrix sentence-in-noise test can be used as a reliable tool to assess speech-in-noise intelligibility in sound-field testing condition. Further study across various sessions would strengthen the present finding.
Development of Customer Scoring Models using Hotel Restaurant Database
Yukyeong Kathy Chong 한국관광학회 2010 International Journal of Tourism Sciences Vol.10 No.1
The current research is designed to apply scoring modeling in database marketing for the hospitality industry. This research seeks to determine if previous historical data can predict future behavior patterns of individuals and groups in terms of frequency of visiting restaurants. The purpose of this study is to develop a scoring modeling to predict existing customers' future behavior using a restaurant database in a hospitality industry. The data set used for this study includes 956 customers and 11,242 restaurant transactions in a hotel from January through December. The current study builds individual models and compares those individual models to an aggregating model in terms of model assessment and prediction power.
Yukyeong Lee,김은성,Sangeun Park,Jeong Min Park,Jae Bok Seol,Hyoung Seop Kim,이태경,Hyokyung Sung,Jung Gi Kim 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.1
Process optimization of additively manufactured Ti–6Al–4V alloy is an important aspect of the production of engineered,high-performance parts for the aerospace and medical industries. In this study, the microstructural evolution and mechanicalproperties of direct energy deposition processed Ti–6Al–4V alloy were investigated using diferent processing parameters. Experimental analyses revealed that the line energy density corresponding to the processing parameters of the direct energydeposition process infuences the properties of additively manufactured Ti–6Al–4V alloy. First, an optimal line energydensity limits the incidence and size of voids resulting from a lack of fusion to enhance both alloy strength and ductility. Second, an excessively high energy density induces the coarsening of prior-β grains to impair both alloy strength with theHall–Petch relationship and alloy ductility due to the plastic deformation instability caused by the limited number of grains. These results indicate that both the extent of fusion and prior-β grain size afect the mechanical properties of additivelymanufactured Ti–6Al–4V alloy. Moreover, the results demonstrate the utility of the line energy density-based approach indetermining the optimal processing parameters for realizing high-performance materials.
OECD 국가의 제약바이오산업 혁신성과 원인조건 조합 분석
김유경(Yukyeong Kim),이상원(Sang-Won Lee) 한국바이오경제학회 2019 바이오경제연구 Vol.2 No.2
본 연구는 OECD 국가들의 제약바이오산업 혁신성과에 영향을 주는 원인조건 조합을 도출하기 위하여 퍼지셋질적비교분석(fuzzy set Qualitative Comparative Analysis) 방법을 사용하여 분석하였다. OECD 29개국을 분석 대상으로 R&D지출, 연구자 수, 규제의 질, 법치주의를 원인변수로 하고, 생명공학특허 출원 수와 수출 점유율을 혁신성과 결과변수로 하여, 혁신성과를 설명하는 원인조건 조합을 도출하였다. 분석결과 제약바이오산업 혁신 성과를 이끌어 내는 원인조건 조합은 제약산업 내 기업의 R&D지출이 크고, 연구자 수가 많으며 동시에 규제의 질이 좋지 않은 경우와 제약산업 내 기업의 R&D지출이 크고, 연구자 수가 많으며, 법치주의 지수가 높은 경우로 나타났다. 제약바이오 혁신성과를 높이기 위해서는 R&D지출과 연구자 수와 아울러 규제완화를 추진하거나 혹은 법치주의를 강화하는 정책이 필요하다는 시사점을 제시하였다. This study analyzed the fuzzy set qualitative and comparative analysis method to derive the causal combination of factors affecting the innovation performance of the pharmaceutical industry in OECD countries. In the analysis of 29 OECD countries, the combination of causal conditions explaining innovation performance was derived by using R&D expenditure, the number of researchers, the quality of regulation, and the rule of law as the causal variables and the number of patent applications and export share. As a result, the combination of the causal factors leading to the innovation results of the pharmaceutical industry is that the R&D expenditure of the companies in the pharmaceutical industry is large, the number of researchers is large, the quality of regulation is bad, the R&D expenditure of the companies in the pharmaceutical industry is large, And the index was high. In order to increase the innovation performance of pharmaceutical biotechnology, it is suggested that policies to promote deregulation or strengthen rule of law along with R&D expenditure and number of researchers are needed.