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류마티스관절염과 만성 호산구성 폐렴에 동반된 호산구성 흉막삼출
지용관 ( Yong Gwan Jee ),라상호 ( Sang Ho Ra ),박유미 ( Yu Mi Park ),차재황 ( Jae Whang Cha ),강용석 ( Yong Seok Kang ),박정하 ( Jeong Ha Park ),강태영 ( Tae Young Kang ) 대한류마티스학회 2013 대한류마티스학회지 Vol.20 No.5
We describe a 48-year-old man with family history of rheumatoid arthritis (RA) affected by chronic eosinophilic pneumonia (CEP) with severe peripheral eosinophilia. CEP might develop as a complication of longstanding active RA. The patient with 5 months history of seropositive RA and chronic respiratory symptoms, alveolar and blood eosinophilia, peripheral pulmonary infiltrates and pleural effusion on chest imaging. The lung may be involved as an extraarticular manifestation of RA. However, CEP is not recognized as a typical lung manifestation of RA, and the two diseases rarely coexist. The effusion was an eosinophil predominant exudates and was characterized by low pH, and glucose level and high lactic dehydrogenase. The patient responded rapidly to combination of steroids and disease modifying anti-rheumatic drugs.
라덕관,박상숙,김유봉,허동균 순천대학교 공업기술연구소 1998 工業技術硏究所論文集 Vol.12 No.-
This study was to investigate the adsorption and movement of Napropamide in soil. In order to find out the adsorption and movement characteristics of Napropamide in soils of sand loam (soil A), silt clay(soil B), and loam (soil C), batch and column tests were performed with respect to shaking time variation, adsorption isotherm, and breakthrough curve. The shaking time to reach the adsorption equlibrium of Napropamide was 12 hours. Freundlich isotherm was fit for the adsorption of Napropamide in soils. soil B had the highest adsorption coefficient of Napropamide, soil Ca and B followed at adsorption isotherm. The slope of breakthrough curve of soil A had the steep, soil C and soil B followed at the adsorption curve. The moving velocity of Napropamide in soils was the lowest of soil B because of its highest adsorption of Napropamide.
라덕관,김유봉,허동균 순천대학교 공업기술연구소 1997 工業技術硏究所論文集 Vol.11 No.-
In order to investigate the physicochemical water quality in Seomjin river basin, water quality analysis was undertaken at 11 sites in the main river and side stream from March 1996 to Fab. 1997. The concentration of BOD, SS, DO, T-N, T-P, and E. coli were 0.4~2.6mg/ℓ, 1.0~24.5mg/ℓ, 6.0~13.8mg/ℓ, 0.218~2.928mg/ℓ, 0.002~0.098mg/ℓ, and 15~500MPN/100㎖, respectively. Heavy metals were not detected in sampling sites. The lower parts of Yo-cheon is the most polluted stream among the main river and side stream in Seomjin river basin. In Seomjin river basin, annual average pollution loads in ton/year were estimated to be 1,660.32 of BOD, 6,151.86 of SS, 1,421.80 of T-N, and 28.91 of T-P. It was found that Seomjin river basin was not polluted to any troublesome level for water supply, industrial, irrigation and fishery purposes.
대학생의 취업스트레스와 자아존중감, 자아효능감, 외모관리행동의 관계
김보라,김유진,김지희,노혜진,오승희,홍지혜,황윤희,박선아 水原大學校 2016 論文集 Vol.30 No.-
Purpose: Many university students are under a lot of job-seeking stress because the employment rate is low. This study sought to determine the relationship between job-seeking stress, self esteem, self efficacy and appearance management behavior amongst university students focusing on nursing. Methods: This descriptive correlational study evaluated the relationships between job-seeking stress, self esteem, self efficacy and appearance management behavior of 340 university students was conducted between September 1 and October 5, 2015. Results: The correlational analysis between job-seeking stress, self esteem, self efficacy and appearance management behavior revealed a negative correlation between job-seeking stress, self esteem and self efficacy and a positive correlation between job-seeking stress and appearance management behavior. In addition, age also correlated with self esteem, self efficacy and appearance management behavior. Conclusion: Stress correlated with self esteem and self efficacy and appearance management behavior. Therefore job-seeking stress may be reduced through not only self esteem and self efficacy enhancement programs but also management according to age.
혈전성 혈소판감소성 자반증으로 발현된 전신홍반루푸스 1예
오명근,유미라,변유미,윤찬영,권세훈,박치영,김상현 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.3
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening syndrome characterized by the classic pentad of clinical features that includes microangiopathic hemolytic anemia, thrombocytopenia, neurologic abnormalities, fever, and renal dysfunction. Early diagnosis and utilization of plasmapheresis can improve the survival rates of patients with TTP. TTP rarely may be seen in association with autoimmune disease such as systemic lupus erythematous (SLE). We report here a 42-year-old female who was presented with severe digital gangrenes, microangiopathic hemolytic anemia, thrombocytopenia, neurologic abnormalities, fever, and renal dysfunction. Her condition responded to combined therapy with high dose steroid, immunosuppressants, and plasmapheresis therapy.
정신분열병 환자에서 얼굴 영상의 작동기억 장애 : 기능자기공명영상연구
이창욱,김태석,주라형,박주미,박여진,김종진,전신수,배치운,김정진,이수정,이철,백인호 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.2
Objectives : Impaired processing of facial information is one of the broad ranges of cognitive deficits seen in patients with Schi-zophrenia. We aimed to elucidate the differences in brain activities involved in the process of facial working memory between schizophrenic patients and healthy comparison subjects. Methods : Twelve patients with schizophrenia were recruited along with twelve demographically matched healthy volunteers as a comparison group. Functional magnetic resonance imaging (fMRI) was used to assess cortical activities during the Perfor-mance of a 2-back working memory paradigm using images of neutral faces as mnemonic content. Rcsults : The patient group performed the tasks with reduced accuracy. Group analysis revealed that the left fusiform gyrus, the right superior frontal gyrus, the bilateral middle frontal gyri/insula, the left middle temporal gyrus, the precuneus, the quadrangular lobules and the vermis of cerebellum showed decreased cortical activities in the patient group. On the other hand, an increased level of activation in the lateral prefrontal cortex and the pahetal lobule was observed from the patient group, all in the right hemisphere. Conulusion : A decreased level of activity in the left fusiform gyrus among the patient group implicates inefficient processing of facial information. An increased level of activation in prefrontal and parietal neural networks from the patient group confirms earlier findings on the impaired working memory of patients with schizophrenia.
정신분열병의 인지적 표지자와 Catechol-O-Methyltransferase Val158Met 유전자 다형성의 연합연구
박해정,박동연,조은영,김나라,전현옥,이유상,이동수,홍경수 대한신경정신의학회 2008 신경정신의학 Vol.47 No.2
Objectives : Catechol-O-methyltransferase (COMT) gene has been identified as a positional and functional candidate gene of schizophrenia. Although specific mechanism of increasing schizophrenia susceptibility by this gene has not been well described yet, recent studies suggest that the valine allele of COMT Val158Met polymorphism may contribute to cognitive decline in schizophrenia. The present study investigated the association between this polymorphism of COMT gene and cognitive markers related to schizophrenia in both schizophrenia patients and normal controls. Methods : The subjects were 78 patients with schizophrenia diagnosed by DSM-IV and 97 normal controls. Comprehensive neurocognitive tests for which performance deficits have been reported in schizophrenia were administered. Genotyping for COMT Val158Met polymorphism was done with SNapShot method. Association analyses between genotype and cognitive functions were performed using ANCOVA and MANCOVA. Results : In the comparison of allele frequencies between patient and control groups, no significant association between the polymorphism and schizophrenia was observed. Significant differences of cognitive performance among genotype groups were not identified in control group. This trend was also observed in the patient group. In the combined analysis of both patient and control groups, there was no significant genotype or genotype-by group effect on any cognitive function measure. Conclusion : These findings do not support a major role of COMT gene in the regulation of the cognitive processes of schizophrenia.
Digital ulceration due to the change of hand microvasculature induced by rheumatoid arthritis
( Yu Ra Sim ),( Yea Jin Lee ),( Sung Jae Choi ),( Young Ho Seo ),( Gwan Gyu Song ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Background: Severe Raynaud’s phenomenon enough to make digital necrosis is a rare manifestation of rheumatoid arthritis(RA) without other evidences of overlapped systemic sclerosis. Here we report a case of a severe Raynaud’s phenomenon with finger tip ulceration and gangrene in uncontrolled RA patient. Case Report: A 54-year-old male with 8-year history of taking weekly methotrexate 7.5 mg for RA visitedour cardiovascular surgery department complaining of 2-week history of ulceration of left third fingertip with Raynaud’s phenomenon. Physical examination revealed tenderness, swelling, and limitation of movement in bilateral wrist, 2nd & 3rd MCP and PIP joints. The ulcerative lesion in left 3rd fingertip was combined with bluish color change. He had normal bilateral radial and ulnar pulses. Left forearm arteriography revealed localized hypervascularity of RA affected joints and multiple occlusions at interosseous arteries and digital arteries, especially most severe in third finger. We increased the dosage of methotrexate to 12.5 mg/week, additionaly preiscribed methylprednisolone 4 mg/day and tadalafil. We strongly recommended quitting of smoking. After 2 months, the ulcerated lesion in fingertip was improved and arthritic joint pain was resolved. Conclusions: In uncontrolled RA activity, deprivation of distal blood flow induced by the shunt like filling of the veins through hypervascularized region in severely affected arthiritic joints, can result in Raynaud’s phenomenon and digital gangrene.