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        Hepatic Cirrhosis Occurring in a Young Woodchuck(Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus(WHV)

        Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

        Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea

      • 급성 및 만성 간질환에서 C형 간염바이러스 항체(anti-HCV)양성률

        김삼용,성자원,김병호,이기천,허승식,길준영,정현용,이헌영,김영건 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

        The prevalence of antibody against hepatitis C virus (anti-HCV) was investigated in 331 patients with various liver diseases from April 1992 to September 1992. The presence of anti-HCV was detected by Lucky HCD EIA test in 331 cases and by (Ortho HCV Antibody ELISA test 148 patients) The results are summarized as follows: 1. Overall, antibody to HCV(anti-HCV) was positive in 37(11%) of 331 patients with various liver diseases. 2. 16(11%) of 144 patients with chronic hepatitis, 2(5%) of 37 patients with alcoholic liver disease, 17(22%) of 76 patients with liver cirrhosis and 2(5%) of 38 HBsAg carriers were positive for anti-HCV.None of 12 patients with acute hepatitis, 11 patients with drug induced hepatitis and 13 patients with hepatocellular carcinoma was anti-HCV positive. 3. HBsAg positivity in patients who had anti-HCV was 24%(9/37). 4. A positive correlation was found between Lucky HCD and Ortho HCV test. Of 128 Lucky HCD negative cases, 124 cases were negative for Ortho HCV ELISA and 4 cases were positive for Ortho HCV ELISA Of 20 Lucky HCD positive cases, 11 cases were positive for Ortho HCV ELISA and 9 cases were negative for Ortho HCV ELISA. These results suggest that hepatitis C virus has an important etiologic role in HBsAg negative chronic hepatitis and liver cirrhosis in Korea. The diagnostic value of Lucky HCD EIA test may be slightly better or equivalent to Ortho HCV ELISA test in the diagnosis of Hepatitis C virus infection.

      • 가새배치에 따른 고층건물의 변위에 관한 연구

        최영화,임헌욱 대구대학교 산업기술연구소 2014 産業技術硏究 Vol.25 No.1

        Mordern structures tend to be high-rise buildings because of the population growth, restraint of lands and the high value of lands. In aspect to the control of lateral displacement, the importance of wind load and seismic load is also increasing to get the resistance against lateral load. The purpose of this study is to analyze the base building and 12-case models according to the bracing arrangement, the relative stiffness ratio of column and girder, the number of floor and the bracing section area by using MIDAS/GENw computer program. The results are as followings ; 1. Case 2 is effective in the vertical bracing arrangement. 2. Case 6 is effectual in the group bracing arrangement. 3. Case 8 and 10 are efficient in the diagonal and the horizontal bracing arrangements, respectively. 4. Case 8 among the diagonal bracing arrangements shows the smallest displacement value in all 12 cases, compared with the base building by decreasing as much as 48%.

      • SCOPUSKCI등재
      • 내시경으로 확인된 상부소화관 용종의 임상적 고찰

        김영건,김병호,성자원,이기천,허승식,이종선,정현용,이헌영 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

        From January 1987 to October 1991, we performed 14,333 cases of upper gastrointestinal endoscopy and diagnosed 527 cases with U.G.I polyp. We assesed these 527 cases and obtained following results: 1) The overall incidence of U.G.I. polyps was 3.6%, and there was no sexual difference. The peak incidence was in 6th decades(32.4%). 2) The U.G.I. polyps were located chiefly at stomach(415 cases, 78.7%), among which antrum occupied antrum 43.5%, body 24.0% and funds 5.1%. And the others were esophagus(6.5%) and duodenum(12.3%). 3) The size of U.G.I. polyp was below 1cm in 72.3%, from 1cm to 1.9cm in 20.7% and above 2cm in 7.0%. According to Yamada' classification, type Ⅰ, Ⅱ, Ⅲ and Ⅳ was 31.9%, 51.3%, 13.7% and 3.0%. 4) Histological nature of U.I.G. polyp were hyperplastic polyp(85.8%), adenomatous polyps(9.3%), carcinomatous polyps(3.3%) and etc. The size of neoplastic polyp such as adenomatous polyps(mean 1.0±0.7cm) and carcinomatous polyps(niean 2.0±1.8) were larger man hyperplastic polyp(mean 0.6±0.4) (p<0.05) 5) The gastric polyps were associated with peptic ulcer(7.5%), gastric cancer(3.2%), other malignancy(3.5%), hepatobiliary disease(5.5%), post subtotal gastrectomy(5.5%). And others(75%) werenot associated with specific disease.

      • 고전압 대전류 회로 해석을 위한 GTO 사이리스터 모델

        구헌희,서기영,권순걸,이현우 경남대학교 신소재연구소 1996 論文集 Vol.6 No.-

        Gate Turn Off Thyristor(GTO)는 게이트 신호로 대전류를 차단할 수 있기 때문에 최근에 대전력 응용 분야에서 각광을 받고 있다. 이들의 대용량 분야에서는 고전압 대전류를 취급하기 때문에 개발시 실험을 하는 것이 곤란하다. 따라서 대용량 회로의 설계와 Simulation을 위해서 GTO의 동작특성을 정확하게 모의할 수 있는 정밀한 Model이 필요하다. 본 연구에서는 PSPICE를 이용하여 2-트랜지스터 구조를 기본으로 하여 GTO의 특성을 표현할 수 있는 각종 회로소자를 부가하여 GTO Model을 개발하였으며, 이 Model의 특성을 평가하기 위하여 스위칭 특성 및 직·병렬 접속에 대한 해석을 하였다. Gate turn off thyristors(GTO) have attractive attention as an efficient switching device for high power applications, primarily due to their alibility to turn off large currents with a gate signal. For the simulation and design of high power circuits, it is necessary to have accurate model which simulate both the static and dynamic characteristics of the GTO. In this study for the simulation of GTO with the program PSPICE. a model consisting of two transistors. passive device, and controlled source was developed. To evaluate the developed. model, simulation was performed for the switching characteritics. serial and parallel connection.

      • 실험적으로 유도된 이독성 난청에서의 Ginkgo Extract의 효과

        이상흔,조영채,도현우,강현욱,조태환 경북대학교 병원 1997 경북대학교병원의학연구소논문집 Vol.1 No.1

        이독성 난청에서의 Ginkgo extract의 효과를 보고자 기닉픽 22마리를 대상으로 이음향방사를 측정하여 난청군과 치료군을 비교 검토한 바 성적을 요약하면 다음과 같다. 난청군에서의 DP-OAE는 대군조에 비해 전 주파수에서 감소 내지 소실을 보였으며4KHz 에서만 선택적으로 큰 감소를 나타낸것도 있었다. Ginkgo estract로 예방 치료한 군에서는 난청군에 비해 DP-OAE가 현저하게 출현 하였으며 정상 DP-OAE소견을 나타낸 것도 있었다. 난청치료군에서도 난청군에 비해 전체적으로 DP-OAE 가높게 출현되고 있었다. 이상의 소견으로 보아 Ginkgo estract가 이독성 난청과 감각신경성 난청에서의 예방 및 치료 효과의 가능성을 제시해 준다고 생각되는 바이다. This study was designed to investigate the effect of Ginkgo biloba extract on the kanamycin induced ototxicity in inner ears 22 guinea pigs. The animals were divied into 4 groups. In ototoxic group, kanamycin was injected 400mg/kg per day for 7 to 10 days. In preventive treated group, kanamycin with same dose and Ginkgo biloba extract(50mg/kg)were simultaneously injected daily for same duration. In post treated toup, Ginkgo extract was treated for 15 days in kanamycin injected group. The Preyer's reflex and DP-OAE (distortion product otoacoustic emissions) were used for the monitoring of hearing changes. In the ototoxic group, the amplitude of DP-OAE was marked decreased or disappeared in all test frequencies or 4KHz only. The Preyer's reflex was disappeared in all ototoxic group. In the preventive treated group with Ginkgo extract, normal DP-OAE or slightly decreased DP-OAE in 4 KHz was noticed. This finding was seemed to be similar to the post-treated group. From the above results, Ginkgo extract is suggested to have beneficial effects for the management of ototoxicity and sensorineural hearing loss.

      • 2석식 포워드 컨버터방식 저압대전류 직류전원장치

        서기영,구헌회,이현우 慶南大學校 附設 工業技術硏究所 1997 硏究論文集 Vol.15 No.1

        저압대전류전원장치의 소형경량화와 효율향상을 위한 요구가 지속적으로 되어오고 있으며 적합한 전력변환방식에 대한 연구도 계속되고 있다. 2석식 포워드 컨버터는 브릿지방식 등에 비해서 변압기 구조가 간단하고 신뢰성있는 동작이 가능하고 고주파화에 적합한 방식이다. 본 연구에서는 2석식 포워드 컨버터방식의 동작모드를 해석하고 DC 30V 1000A의 직류전원장치의 주회로를 설계하고 컨버터의 안정한 동작을 위하여 보상회로를 설계하여 Simulation을 통하여 동작특성을 확인하였다. Efforts to improve low voltage high current DC power supply currently are forcused on increasing efficiency and decreasing size and weight. The two transistor forward converter features simplicity in power transformer sturucture and drive circuit as well as high reliability compare with bridge type converter. In this paper, operation mode of two transitor forward converter is analysis and DC 30V 1000 A power supply is designed and verified the operation characteristics of converetr through simulation.

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