Caffeine이 지구성 운동 수행능력에 미치는 영향과 억제성 아미노산에 의하여 활성화되는 이온통로의 조절작용

김은경,김영표,천병옥,이계영,김연정,임백빈,조영욱,김창주,김성수 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1

To investigate the effect and mechanism of caffeine on endurance exercise, two experiments were performed. First, to test caffeine effect on aerobic exercise, 200-300g Sprague-Dawley rats were used and three groups, control group, low caffeine injection group and high caffeine injection group, were divided. Blood smpling by heart puncture were done at rest, after 30 min treadmill exercise, and after maximal exercise. Blood glucose, free fatty acid concentration were detected and following results were obtained. Glucose concentration showed significant difference between groups(p=0.0305) and also significant changes were exhibited between time(p=0.0004). Free fatty acid concentration had no difference between groups. but had significance between times(p=0.00065). Exercise endurance performance time showed significant difference(p=0.02350 in high caffeine injection group compared to control group. In this experiments, endurance exercise capacity was increased by caffeine injection. Therefore, second experiment was performed to investigate the effect of caffeine on ion current induced inhibitory amino acid neurotransmitter. GABA and glycine. Single periaqueductal gray neuron was acutely dissociated and nystatin perforated patch clamp was performed under voltage clamping condition. Caffeine evoked outward current in PAG neuron dose dependent manner. 1mM of caffeine application had no response. but 3mM caffeine evoked about 32.5±8.539pA outward ion current and 10mM caffeine evoked about 215.46±19.4pA outward current. 10^-2mM GABA activated Cl￣current and recorded by inward current. Caffeine inhibited GABA activated Cl￣ current concentration dependent manner. 10^-2mM of caffeine had no effect on 1-^-2mM of GABA response. but 10^-1mM caffeine inhibited GABA activated Cl￣ current about 5.74±2.13%, 1mM caffeine inhibited about 17.25±2.70%, 10mM caffeine inhibited GABA response about 45.31±7.71%. 10^-1mM of glycine activated Cl￣ current and also recorded by inward current. Caffeine inhibited glycine activated Cl￣ current concentration dependent manner. 10^-2mM caffeine decreased glycine activated Cl￣ current about 4.61±1.650%, 10^-1mM caffeine decreased about 6.49±2.24%, 1mM caffeine decreased about 26.82±4.27%, and 10mM caffeine decreased glycine response about 94.47±1.39%. These results suggest that caffeine inhibite inhibitory amino acid, GABA and glycine, this response causes excitation of CNS and this seems to be the basic mechanism of increasing effect to aerobic exercise performance by caffeine.

유아교육과 신입생 및 졸업반 학생의 교직 신념과 현직 유치원 교사의 교직 신념에 관한 비교 연구

이영자,이정욱 德成女子大學校 1996 德成女大論文集 Vol.27 No.-

This study was conducted to investigate entry level early childhood teacher education students' beliefs about ideal teachers, children, and parents. In addition, this study compared entry level students with exit level students and inservice kindergarten teachers in their beliefs. The subjects were 30 entry level and 28 exit level early childhood teacher education students and 44 inservice kindergarten teachers. Questionnaires were used to collect data about beliefs of teacher education students and inservice teachers. The major findings of this study were as follows : 1. Both teacher education students and inservice teachers emphasized affective/ interpersonal dimensions as well as cognitive/academic dimensions in selecting the important characteristics of ideal teachers. 2. Only entry level students chose 'willingness to give extra time and effort' as an important characteristic for ideal teachers while both exit level students and inservice teachers did not. 3. Both teacher education students and inservice teachers emphasized that the ideal child would respect others and themselves, be interested and actively involved in activities. In addition, entry level students and inservice teachers emphasized 'expressing themselves very well' as an improtant characteristic for ideal children while exit level students did not. 4. Both teacher education students and inservice veachers selected 'love and warmth', 'respect for their children'. and 'consistent discipline with clear explanation' as improtant characteristics for ideal parents. Entry level students also chose communication with children' as an improtant characteristic for ideal parents while exit level students chose 'encouraging and supproting children'.

地球科學的인 內容에 重點을 둔 環境敎育에 關한 硏究 : 國民學校 兒童들의 自然觀에 關한 調査 A Report of the Survey on the Chield's Conception of the Nature

申載旭,崔榮宰 서울교육대학교 과학교육연구소 1984 科學과 數學敎育 論文集 Vol.10 No.-

Productivity S/W 학습용 웹 코스웨어에서 상황맥락적 오류교정 패드백이 학업성취도에 미치는 영향

김도윤,배영권,백장현,이태욱 한국컴퓨터교육학회 2004 컴퓨터교육학회 논문지 Vol.7 No.1

현재 웹 코스웨어에서의 형성평가와 이에 대한 피드백 시스템은 많이 구축되어 있다. 그러나 대부분 웹 코스웨어의 형성평가와 사용자 반응에 따라 제공되는 피드백은 실제의 문제 상황과 거리가 먼 상태에서 단순한 텍스트 형태로 정오의 표시, 정답 표시, 관련 정보의 표시 등을 제공하고 있다. 이는 자칫 피드백의 교정적 기능을 약화시켜 학습자의 학습 내용에 대한 이해와 학습 전이의 가능성을 감소시킬 수 있다. 또한 구성주의 학습이론에 따르면 학습은 그 것이 발생하는 상황에 영향을 받고 지식이 어떤 맥락에서 학습했느냐에 따라 다르게 학습되며 전이된다고 한다. 이런 배경에서 본 연구는 웹 코스웨어에서 형성평가를 실시할 때 학습자의 반응에 따라 피드백을 문제 상황과 밀접하고 유사하게 상황맥락적으로 제시할 수 있는 상황맥락적 오류고정 피드백시스템을 설계하고 구현하였다. 그리고 실제 Productivity S/W를 학습할 수 있는 웹 코스웨어에 ‘정오/정답제공형 피드백', ‘관련정보제공형 피드백’‘상황맥락적 오류교정 피드백’을 적용한 후 ‘상황맥락적 오류교정 피드백’이 학업 성취에 있어서 다른 두 가지 유형의 피드백보다 더 효과적인지를 검증하였다. Today there are many Web courseware systems for formative evaluation and feedback. Formative evaluation and feedback provided according to users’ response in most Web courseware systems, however, are simple texts showing only whether correct or wrong, correct answers, relevant information, etc., far deviated from actual context. Thus such a system may weaken the corrective function of feedback and, as a result, reduce learners’ understanding of contents and the possibility of leaming transfer. In addition, according to the learning theory of constructivism, learning is influenced by the situation, in which it happens, and knowledge is learned and transferred differently depending on the context in which it is learned. In the background, this study designed and implemented a contextual error-correction feedback system that can provide feedback in a context closely related and similar to the relevant situation according to the response of learners when formative evaluation is carried out in Web courseware. In addition, it applied ‘correction/correct-answer-providing feedback’, ‘relevant information providing feedback’ and ‘contextual error-correction feedback’ to Web courseware for learning actual productivity S/W and verified if ‘contextual error-correction feedback’ is more effective than other two types of feedback for learners’ academic achievement.

멀티미디어 제작을 통한 초등 정보영재교육에 관한 연구

남승현,배영권,김도윤,구덕회,이태욱 한국컴퓨터교육학회 2005 컴퓨터교육학회 논문지 Vol.8 No.2

창의성 및 정보과학적 특성을 기반으로 한 정보영재 판별도구 개발연구

신승용,신수범,배영권,이태욱 한국컴퓨터교육학회 2004 컴퓨터교육학회 논문지 Vol.7 No.4

오늘날 정보화가 빠르게 진행되면서 정보과학의 중요성이 수학, 과학의 중요성 못지않게 대두되고 있기 때문에 이 분야의 영재 역시 조기에 판별하여 교육시켜야 한다는 필요성이 강조되고 있다. 하지만 이에 대한 연구는 초보적인 단계에 머물고 있다. 이에, 본 연구에서는 영재의 판별에 대한 이론적 고찰을 통해서 영재의 특성, 정의 및 판별방법과 도구의 제작과정을 살펴보고 영재의 올바른 판별과정을 조사, 분석하였다. 또한 이를 바탕으로 정보과학의 기반이 되는 이산수학의 특성을 규정하여 이를 바탕으로 정보영재의 특성 및 정의를 내렸으며 이를 근거로 정보영재를 판별할 수 있는 도구를 제작하였다. 판별도구를 이용하여 적용한 결과 판별도구는 신뢰성이 있는 것으로 분석되었으며 향후 정보영재의 의미 있는 판별도구로 활용될 수 있을 수 것이다. Since the science of information is appearing no less important than mathematics and natural science as our society is rapidly becoming information-oriented, the necessity to distinguish prodigies of this field and to educate them as early as possible is also being emphasized. Unfortunately, however, the pertinent study is still in its beginning stage. In this study, I have reviewed the character, definition and method to distinguish prodigies and the procedure of developing a test, as well as researching and analyzing the proper process of distinguishing prodigies, through theoretical contemplation on the method of distinguishing the gifted children. Also, I have characterized and defined the information prodigies after clarifying the character of 'Discrete Mathematics' which becomes the basis of the science of information, paving the way to make a test method that can distinguish those information prodigies. As a result of our applying the system by using the distinction test, it turned out that the distinction test was pretty reliable. Accordingly, it can be utilized as a significant distinction test for information prodigies in the forthcoming future.

Anterior and Posterior Overjet for Clinical Arch Coordination using 3-dimensional Analysis

Young-Wuk Lee,Mohamed Bayome,Seung-Hak Baek,Yoon-Ah Kook 대한치의학회 2009 Journal of korean dental science Vol.2 No.2

Young Leaves of Reed (Phragmites communis) Suppress the Inflammatory Factors of I-kB, AP-1 and STAT, but Activates the Antioxidative the Home Oxygenase-1 Activation in Lipopolysaccharide-stimulated RAW 264.7 Macrophages

Chae-Young Jang,Kyung-Yun Kang,Sung-ju Lee,Beom-Gyun Jeong,Jun-Ki Park,Ho-Yeol Jang,Yun-Seo Oh,Kyung-Wuk Park 한국식품영양과학회 2020 한국식품영양과학회 학술대회발표집 Vol.2020 No.10

Surgical Treatment without Blood Occlusion in Small Animals with Cardiovascular Diseases.

Hun-young Yoon,Soon-wuk Jeong,Joon-young Kim,Hyun-jung Han,Sang-hyuk Park,Jeong-yoon Park 대한수의학회 2003 대한수의학회 학술대회발표집 Vol.2003 No.-

Antagonizing effect of protein kinase C activation on the μ-opioid agonist-induced inhibition of high voltage-activated calcium current in rat periaqueductal gray neuron

Cho, Young-Wuk,Han, Seung-Ho,Min, Byung-Il,Rhee, Jeong-Seop,Norio Akaike 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2001 No.-

Opioids have been thought to induce analgesia by activating the descending pain control system, especially at the level of periaquenductal gray, and regulate the neurotransmitter release through the inhibition of calcium channel. In the present study, the modulatory effects of protein kinase C and protein kinase A on the μ-opioid agonist-induced inhibition of the high-voltage activated calcium current were examined in the acutely dissociated rat periaqueductal gray neurons with the nystatin-perforated patch-clamp technique. Among 505 neurons tested, the barium current passing through the high-voltage activated calcium channels of 172 neurons (34%) were inhibited by 32±3% with the application of an μ-opioid agonist, [D-_Ala^2, N-MePhe^4, Gly^5 -ol]-enkephalin (DAMGO, 1 μM). The barium currents itself and the DAMGO-induced inhibitory effects were not affected by the application of either an adenylate cyclase activator (forskolin, 1μM) or a protein kinase inhibitor (staurosporin, 10nM) for 2 min. The DAMGO inhibition was completely and irreversibly antagonized by the application of a protein kinase C activator, phorbol-12-myristate-13-acetate (PMA, 1μM) for 2 min without any alteration of the barium current itself. However, the antagonizing effect of PMA was completely abolished by the application of 10 nM staurosporin for 2 min. After then, PMA did not show the antagonizing effect any more. Inversely, when staurosporin was applied before PMA, the antagonizing effect of PMA was also not shown. These results demonstrate that the μ-opiod agonist-induced inhibition of the periaqueductal gray neuronal high-voltage activated calcium current can be antagonized by protein kinase C activation. This finding may provide us a significant clue to understand the action mechanism of opioid-induced analgesia in the periaqueductal gray. ⓒ 2001 Elsevier Science B.V.All rights reserved.