야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

유기질 폐기물의 분해촉진 방안을 통한 매립지의 조기 안정화에 관한 연구

정연규,임성균,정연균 연세대학교 산업기술연구소 1991 논문집 Vol.23 No.1

In this study, the stabilization process of solid wastes was investigated related to bio-gas production, using lysimeters filled with municipal wastes contained a high percentage of organic refuse. The lysimeters were operated four types; continual through-flushing with water, leachate recirculation, leachate recirculation with pH control, and in-situ condition. Also each type was consisted of three lysimeters and operated with detention time 3 days, 6 days, 12 days, respectively. As the results, inorganic material, ??, was decreased by physical dilution and organic materials such as COD, VS were decreased by biological activity as well as dilution. The ratio of VS to TS was decreased proportionately in the course of time. Leachate recirculation was shortening the period of stabilization by accelerating bio-degradation of organic wastes. And the reactors operated leachate recirculation with pH control accelerated the rate of gas production.

3-D 동작 분석 장치를 이용한 한국성인(20대, 30대)의 동작 범위에 관한 연구

임현균,김진호,박수찬,류신아,이영신 한국운동역학회 1998 한국운동역학회지 Vol.8 No.2

Devices, such as a goniometer, have been used to measure a human being's active range of motion, but interferences between subjects and testers have affected the result precision. In this study, 56 dynamic motion ranges were measured using a 3-D motion analysis system which is quite accurate (2mm error for 1m). The 3-D motion analysis system consists of VICON 140, data acquisition system, and data analysis program (KRISSMAS). 80 Korean subjects (40 males, 28±6.1 aged and 40 females, 28.4±6.9 aged) participated. Subjects were divided into 4 groups by Ro¨hrer's index based on National Anthropometric Survey of Korea 1997. Basic statistical analysis were performed using SPSS (ver. 8.0) programs after refining data. Various comparisons were performed for the right and left side, male and female, age groups (20's, 30's. and 40's-60's) using previous studies. The results show that female subjects have more flexible joints in the neck, hip, ankle, and wrist, while male subjects have more flexibility in their waist. But most of the significances were not high (>0.05). The prediction that the right side of Korean bodies would be mort flexible was not a good hypothesis. And the joints flexibilities are not correlated with Ro¨hrer's Index.

플라타너스(Platanus orientalis L.)의 계절별 Betulinic acid 함량 및 생리활성

김영균,고영남 國民大學校 山林科學硏究所 2001 山林科學 Vol.13 No.-

최근 폐암, 난소암, 흑색종 등 각종 악성종양 및 후천성면역결핍증(AIDS) 에 대하여 우수한 치료효과를 가지고 있다는 연구결과가 빈번하게 발표되고 있는 triterpene화합물 betulinic acid를 계절별로 플라타너스를 채취하고 MeOH 추출물로부터 분리하였다. 순수하게 정제된 betulinic acid의 함량을 비교하였고, 생물학적 활성을 검정하였다. A lupane type triterpenoid, betulinic acid has been known to have lung cancer, ovarian cancer, human melanoma and other tumor growth inhibitory activities and also anti-HIV activity. In this research, we collected P. orientalis in every seasons and observed seasonal changes of betulinic acid in the species. Cytotoxic activity of betulinic acid is also shown in this report.

Lithium 투여가 흰쥐의 신장에 미치는 영향에 관한 연구

김영석,강상균,김창진 순천향대학교 1991 논문집 Vol.14 No.2

Lithium, an element ion, has been used in the psychiatric field to manic illness but in brings nephritis, diabetes insipidus and nephrotic syndrome. Most of the studies on the nephrotoxicity were described only in the morphological aspects, and functional study was unclarified. This study was carried out to observe lithium nephrotoxicity in both functional and morphological aspects. The lithium carbonate was administered to rat peritoneum(50mg/Kg) daily for 10, 20, 30 and 40 days. The urinw pH and proteinuria were measured and the kindney tissue was observed with light and electron microscopy. The results are as follow : 1. The urine pH was 5.5-7.0(normal 7.5-8.5) in the groups of lithium administration longer than 10 days. 2. The albuminuria (+) was observed in the groups of lithium administration longer than 10 days, but the severity of proteinuria was not related to duration of administration. 3. The proximal convoluted tubules and collecting ducts were dilated with epithelial cell degeneration in the experimental group of lithium administration for longer than 10 days. 4. The AgNORs in the tubular epithelial cells were markedly increased in number but those in the mesangium showed only slight increase in the experimental group of lithium administration for longer than 10 days. 5. The glomerular basement membrances were focally thickened and the epithelial foot processes were fused in the experimental group of lithium administration for longer than 10 days. The above results indicate that lithium thought to be toxic to the kidney causing not only functional but also morphological derangement. The renal functions of the patients under lithium regimen should be carefully mornitored to avoid nephrotoxicity, and further studies would be necessory to elucidate the precise mechanisms of lithium nephrotoxicity.

활성탄을 이용한 낙동강 상수원수의 수처리 효과

임영성,강관호,이홍재,서동철,허종수,손보균,조주식 한국환경농학회 2002 한국환경농학회지 Vol.21 No.3

상수원수를 보다 효과적으로 처리함으로서 양질의 수돗물을 공급하기 위한 기초자료를 얻고자 낙동강 상수원수를 대상으로 활성탄처리에 의한 공탐체류시간 및 활성탄 여층 깊이에 따른 수처리 효율과 생물활성탄으로서의 이용 가능성을 조사한 결과는 다음과 같다. 공탑체류시간(EBCT)에 따른 수처리 효율은 EBCT가 증가할수록 증가되었으나 운전시간이 경과함에 따라 활성탄 흡착능력은 감소되어 처리효율도 서서히 감소하였다. 활성탄 여층깊이에 따른 pH 변화는 활성탄 층 깊이에 따라 거의 없었으며, D0는 활성탄 층 깊이가 깊을수록 서서히 감소하였다. KMnO^4 소비량, UV254 흡광물질 DOC 및 THMFP 처리효율은 활성만 표층으로부터 하부로 내려갈수록 증가하였으며, 운전시간이 경과할수록 활성탄 상층부에 형성되어 있던 흡착대파 하부로 이동하였다. DOC의 상당 부분이 활성탄여과지에 서식하는 미생물 작용에 의해 분해 제거되는 것으로 나타났으며, 운전개시 126일 후의 BAC에서 활성탄 표층으로 부터깊이 20 cm 부근에 미생물이 1.1*10^7 cell/cm^3 이상 존재하는 것으로 관찰되어 생물활성탄 조건을 만족시키고 있었다. This study was carried out to evaluate the pollutant removal efficiencies of the advanced drinking water treatment using mated carbon process. For raw water, Nakdong river was used. From the activated carbon adsorption experiment, the following results were obtained. The efficiency of water treatment enhanced with increase in empty bed contact time. Variation of pH was not detected to the bed depth, but DO content gradually decreased with the bed depth, Removal efficiency of KMnO₄ consumption, UV254 absorption, DOC and THMFP also were increased by increasing in the bed depth. Transition of adsorption zone from upper parts of the bed to the lower parts were detected as treatment periods increased. Large portion of DOCs were degraded and removed by the microbes growing on the surface of activated carbons. Cell numbers of microbes were estimated over 1.1 × 10 exp(7) cell/㎤ at the depth of 20 ㎝ from the surface 126 days after starting operation. The results shown that the activated carbon filter was successfully acted as a biofilm filter.

pH 조절에 의한 쌀세척 폐수의 처리

노홍균,김지숙,이문이,조영인 대구효성가톨릭대학교 식품과학연구소 1994 식품과학지 Vol.6 No.-

여러 pH 조건 및 키토산 농도하에서 쌀세척 폐수로부터 부유성 고형물을 효과적으로 응집, 회수할 수 있는 방법을 모색하였다. 키토산 첨가에 따른 탁도감소효과는 pH가 낮아짐에 따라 작았으며 pH 6 이상에서는 키토산 농도가 증가함에 따라 현저히 컸다. 그러나, 폐수의 탁도감소는 키토산 농도와는 관계없이 pH 4일 때 가장 효과적 이었으며 pH가 증가함에 따라 저하하였다. 쌀세척 폐수내의 부유성 고형물은 폐수의 pH를 4로 조정한 후 원심분리하므로서 가장 효과적으로 침전, 회수할 수 있었다. 이 때 탁도감소는 99% 이상을 나타내었으며, 폐수내 부유물질의 농도차와 pH 조정제로 사용된 산종류는 탁도감소에 영향을 미치지 않았다. 폐수의 탁도감소 효과는 저장기간이 길어짐에 따라 저하하였다. Treatment of rice-washing wastewater was considered under various pH levels and chitosan concentrations. Compared with the control test, addition of chitosan at the various concentrations did not noticeably enhanced turbidity reduction at pH 4 and 5, but greatly enhanced at above pH 6. However, reduction of turbidity in the wastewater, irrespective of chitosan concentrations, was the greatest at pH 4 and became lower by increasing pH. Suspended solids in the wastewater were the most effectively recovered by pH adjustment of the wastewater to 4 followed by centrifugation, with over 99% reduction in turbidity. Different concentrations of suspended solids in the wastewater and various kinds of acids used for pH adjustment did not affect turbidity reduction. Increasing storage periods of the wastewater resulted in lower reductions in turbidity.

개다래의 함유성분에 관한 분석

김영균 國民大學校 山林科學硏究所 2003 山林科學 Vol.15 No.-

개다래(Actinidia polygama Max.)의 함유성분을 분석하고 생리활성을 검정하여 유용한 생리활성 물질을 찾아내고자 본 연구를 실시하였다. 따라서 개다래를 MeOH로 추출한 후, 여러 가지 용매로 분획을 하여 각 분획에 대한 항암활성 그리고 항바이러스 활성을 검정하였다. 각 분획의 바이러스에 대한 뚜렷한 약효를 나타내는 시료는 발견되지 않았다. 항암활성의 지표로 사용된 암세포에 대한 세포독성은 사용된 5개의 세포군에 대하여 hexane fraction과 수층에서는 나타나지 않았지만 BuOH fraction에는 중간정도(ED_(50), 25±5 ㎍/ml)의 효과가 나타나고, CH₂Cl₂와 EtOAc fraction은 모두가 BuOH fraction보다는 강한(ED_(50), 15±5 ㎍/ml)정도의 효과가 나타났다. In order to find biologically active compounds the extract of Actinidia polygama Max. was examined. In this study the MeOH extract was partitioned with hexane first to obtain hexane fraction, followed by CH₂Cl₂, EtOAc, and BuOH to obtain corresponding fractions. For each fraction, antiviral and tumor-cell cytotoxicity were tested. Significant antiviral activity was not observed in all the fractions tested. Cytotoxicity, however, on various tumor cell lines was observed in BuOH fraction with medium extent(ED_(50), 25±5 ㎍/ml) and shown relatively strong(ED_(50), 15±5 ㎍/ml) in CH₂Cl₂ and EtOAc fractions.

21세기를 향한 국민 생활체육의 과제

서재균,김승일,윤우상,박영진,곽은창 경희대학교 사회체육연구소 1996 體育科學論叢 Vol.- No.9

The purpose of the present study was to investigate the participation patterns of middle aged subjects, and to make suggestions for the promotion of the sport-for-all movement in Korea. The results of a questionnaire answered by 2125 middle aged male and female subjects were compared between sexes, age groups and educational back-ground using SAS computer program. The conclusions of this study were as follow: 1. Most subjects answered that they had very limited leisure time during week days and week ends. 2. It was shown that most middle aged subjects preferred to rest instead of participate in sport activities during their leisure time. 3. The intensity and frequency of sport activity were too low to improve cardio-vascular endurance. 4. To improved the availability of sport facilities, better management was recommanded.

두릅나무의 함유성분에 관한 분석연구 : 땃두릅나무의 항암활성과 그 성분(Ⅰ)

김영균,고영남 國民大學校 山林科學硏究所 2002 山林科學 Vol.14 No.-

땃두릅나무는 한방에서 해열이나 강장제의 원료로 사용되는 생약제료이다. 아직까지 본 수종에 대한 화학적성분 그리고 이들의 생리활성에 관한 과학적인 연구가 매우 적은 상황이다. 본 연구에서는 본 수종의 sesquiterpenoids과 하나의 polyene 성분의 분리와 구조동정 그리고 이들의 암세포의 성장억제 효과등을 평가하였다. 구조분석을 하기 위하여 ^1H-, ^13C-NMR, MS, FT-IR등의 분광학적 기기를 사용하였다. Echinopanax horridum (Non Decne.) Kom. (Araliaceae) has been known as the herbal medicine for removal of fever, tonic etc. in Korea. Until now, No studies have been reported on its chemical constituents and biological activities for this species. In this report, sesquiterpenoids and a polyene from Echinopanax horridum (Non Decne.) Kom were studied. The structures were established by spectroscopic methods such as ^1H and ^13C NMR, MS, FT-IR. Tumor cell growth inhibition activities were tested for the extracts and the isolated compounds.