유산균들의 콜레스테를 저하성, 내산성, 내담즙성, 항생제 내성 비교

박소영,고영태,정후길,양진오,정현서,김영배,지근억 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.3

기능성 요구르트의 제조에 사용되는 유산균은 인체에 유익한 생리활성과 우수한 생존능력을 보유하고 있는 것이 바람직하다. 본 연구에서는 다양한 유산균주의 산과 담즙 및 항생제에 대한 내성을 조사하였으며 in vitro에서 콜레스테롤 저하능을 조사하였다. In vitro에서 콜레스테롤 저하능이 우수한 13균주를 선발하여 이들의 동결건조 분말을 고 콜레스테롤 식이의 실험쥐에 투여하였다. 그 결과 8균주는 비 투여구보다 유의적으로 18.3~27.3%의 콜레스테롤 저하능을 나타냈다(P≤0.05). 이들 중에서 Bifidobacterium infantis AM-220, Lactobacillus AM-245, Streptococcus MA-1의 3균주를 이용하여 요구르트를 제조한 후 동결건조 분말을 이용하여 급여실험을 수행한 결과, 총 콜레스테롤과 LDL 함량이 유의적으로 감소하는 것으로 나타났다. For a probiotic yoghurt it is desirable to utilize lactic acid bacteria with a high survival rate and beneficial function to human beings. We have examined a variety of lactic acid bacteria to assess the acid and bile tolerance and antibiotic resistance. In addition, an in vitro culture experiment was performed to evaluate their ability to reduce cholesterol levels in the growth medium. Thirteen strains were selected from in vitro cholesterol assays and fed to Sprague-Dawley rats with a high-cholesterol diet. Among the 13 strains tested, 8 strains were shown to reduce serum cholesterol levels significantly after 24 days of administration in vivo. Rats were fed lyophilized yoghurt powder fermented with a combination of 3 selected strains: Bifidobacterium infantis AM-220, Lactobacillus AM-245, and Streptococcus MA-1. The levels of total cholesterol and low density lipoprotein were significantly lower (p≤0.05) in rats fed the yoghurt powder compared with control group. These studies suggest that yoghurt fermented with appropriately selected lactic acid bacteria may have a anticholesterolemic effect.

2개월 남아에서 발병한 Malignant Ectomesenchymoma

황지영,서지현,김점수,김용숙,이수진,박찬후,김유경,박선후,이정희,안인옥,정기현,박병규 대한소아과학회 2001 小兒科 Vol.44 No.8

이화방어기제검사 표준화연구

김재은,김정규,박영숙,이근후 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.3

This study aimed at an evaluation of the reliability and validity of Ewha Defense Mechanism Test(EDMT) for standardization during the period from June 25 to July 10 with nationalwide sample which was standardized by Rhee Kun Hoo. Kin Jae Un. Kim Jung Kyu. and Park Young Sook. The number of subjects were 1.323 who were sampled by the method of proportional stratification on age. sex. education. local area variables. This test is composed of 20 defense mechanism subscales and total items of the test are 200. The results were as follows : 1) The range of means of each scales were from 2.70 to 3.34 and the range of items standard deviation was from .71 to 1.28. 2) The corrected item-total correlation coefficients were than .10 for all items except two items which was the index of internal consistancy. 3) The spearman-Brown split-half reliability coefficients were more than .66 and the retest reliability coefficients were more than .72 for all scales. 4) By the evaluation of the cross validation with “16 Personality Factor Inventory”. it was found that 11 factors were consistent with expectation among 16 factors so that the result of cross validity was moderately sufficient. 5) By the factor analysis. four factors were extracted. Factor 1 was “unstable sensitization defense mechanisms”which were acting out, displacement, somatization. dissociation. projection. and passive-aggressive behavior. Factor 2 was “ego-expansive defense mechanisms” which were composed of controlling. distortion. altruism. humor. and sublimation. Factor 3 was “ego-denial defense mechanisms” which were reaction formation. bragging identification. and regressin. Factor 4 was “reality evasive defense mechanisms” which were denial rationalization. suppression. anticipation. and evasion.

문서작성과 인영 날인의 선 후 관계에 관한 연구 : 필적과 인영 작성 관계의 순서에 대하여

이영수,최섭,김동욱,양후열,진명수,박찬문 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

타크린염산염의 피부투과도 연구

조영주,최후균 조선대학교 약학연구소 1998 藥學硏究誌 Vol.19 No.1

Tacrine (9-amino-l,2,3,4-tetrahydroacridine), a reversible acetylcholinesterase inhibitor, is used for treating the symptoms of mild to moderate Alzheimer's disease. On per oral administraton, however, tacrine appears to exhibit side-effects such as dose-dependent and reversible hepatotoxicity. To overcome this disadvantage, we investigated the feasibility of developing transdermal drug delivery system for tacrine. The effects of various solvents on the permeation rate of tacrine salt across hairless mouse skin were examined using flow-through diffusion cell system. The solubility of tacrine salt in the solvents used in percutaneous absorption study was obtained using equilibrium solubility method. Among tested vehicles, octanol and propylene glycol/oleyl alcohol mixtures showed the highest permeability of tacrine salt. Theoretically, the higher the solubility, the lower the permeation rate. However, it was not possible to demonstrate any correlationship between the solubility and the percutaneous absorption rate of tacrine salt. The results indicate that some of the solvents may change the barrier property of the skin and/or carrier mechanism may be involved.

公敎育不平等現狀에 대한 批判的 談論

安榮厚 제주한라대학 2002 論文集 Vol.26 No.-

The equal opportunities for education would be meaningless if the equal access to public education is considered as the only factor. When we connect this issue with the level-up of education in quality, we still have many problems to solve, which can be related to equalized education. Equalized education is not only about equalized opportunities, but also about the process and the results of education. As the result of this study on equalized education based on the above-mentioned view, I define the following four issues as the major factors in order to improve the quality of education. 1. whether the whole society can change its thought about what equalized education really means. 2. how educational effects or results will be equalized by the application of the positive differentiation-principle. 3. whether the public can clear away their relatively lost minds arising from the expectation of the school education. 4. how the government perceives the reality of education and how actively it tries to make systematic remedies and supports.

기초화장용 제품 중 크림과 로션제의 안정성 평가방법

조혜영,이석,백승희,최후균,이용복 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.4

This study was attempted to develop the physicochemical and morphological stability test methods for the cream and lotion formulations among the cosmetic foundations and to provide the guidance for the stability methods with respect to basic emulsions and creams. With these developed stability test methods, we can evaluate the expired date or life time of the available basic cosmetics, especially basic lotions and creams. Also, the stability test methods established in this study can be used as a guideline to test physical and morphological stability of cosmetics in the future. Thus, we selected two types of basic cosmetics such as lotions and creams made by four different cosmetic companies and applied them to stability test methods depending on the temperature changes such as temperature cycling and freezing-thawing cycling test. After the temperature changes, the conductivity, turbidity, particle size, creaming ratio and pH changes of the creams and lotions were evaluated and morphological changes such as crystal formation, oder, color and feeling of the creams and lotions were also tested. As the results of the stability tests, all the tested creams and lotions except for one lotion were stable. Therefore, it may be concluded that these short-term accelerated stability tests as physical stability test depending on the temperature change study were suitable for the stability testing methods for the basic cosmetics and may be useful for the establishment of the guideline for the stability test of cosmetics.

개의 腎臟機能에 미치는 側腦室內 Prostaglandin A₂의 影響

高光厚,鞠永棕 全南大醫大 1979 전남의대학술지 Vol.16 No.2

학생중심의 활동학습지를 통한 수학과 학습부진아 지도의 효과분석

오후진,허영애 공주대학교 과학교육연구소 2003 과학교육연구 Vol.34 No.-

수학의 특성상 기초학력의 결손으로 인하여 학습에 흥미를 상실한 많은 학습 부진아들이 수학은 재미없고 어렵고 싫증나는 과목이라는 편견과 선입견으로 수학과 학습부진을 더욱 가중시키고 있다. 따라서 수학에 대한 흥미를 유발시켜 수학 교육의 질적 향상을 도모하고 자신감과 성취감을 갖게 하며 좌절감에서 벗어나게 하고자 학생중심의 활동학습지를 통한 교수-학습방법으로 지도하고 학업 성취도 및 정의적 영역에서의 효과를 검증했다. 그 결과 부진학생의 학업성취 및 흥미도에 긍정적인 변화가 있었다. The under-achieving students of non-learning think that because of the mathematical characteristics the mathematics are uninteresting, difficult, tired through the failure of the elementary learning and with many prejudice & preconception the mathematics increase more under-achieving learning. So I set up next assumption in order to verify the effectiveness in the schoolworks & the domain (interest) that through the arising about the mathematical interest I planned the mathematical qualitative improvement, there guided the teaching-learning method through active learning for students to escape collapse with the self-confidence, achievement. Assumption 1. The learning through active learning for students will be more effective in mathematical schoolworks than in mainly teacher-lecturing learning(The schoolworks of all students) Assumption 2. The learning through active learning for students will be more effective in the under-achieving students teaching mathematics than in mainly teacher-lecturing learning(The schoolworks of the under-achieving students) Assumption 3. The learning through active learning for students will be more effective in the interest-arising than in mainly teacher-lecturing learning(The interest of all students) Assumption 4. The learning through active learning for students will be more effective in the interest-arising of the under-achieving students teaching mathematics than in mainly teacher- lecturing.(The interest of the under-achieving students)

소실문자 판독에 관한 연구

양후열,김동욱,최섭,진명수,이영수,나기현 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-