흰쥐 시상하부에서 NMDA에 의한 c-fos의 발현

이영기,최기열,이원돈,유영복,이왕재,황덕호,조사선,장가용 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.3

Multiple myeloma 환자에서 Bortezomib치료 후 발생한 마비성 장폐색증 1례

김준영,이원식,손창학,박성길,진한영,박석주,조영완,정은욱,강명주,박정하,주영돈 인제대학교 2006 仁濟醫學 Vol.27 No.-

Bortezomib is the first clinically available proteasome inhibitor that is clinically effective in the treatment of multiple myeloma. A proteasome inhibitor acts through multiple mechanisms to arrest tumor growth, tumor spread, and angiogenesis. The main adverse effects of bortezomib are gastrointestinal symptoms, cytopenia, fatigue, and peripheral neuropathy. To date, severe paralytic ileus has not been reported as a toxic effect of bortezomib treatment in multiple myeloma. Bortezomib is a novel agent that has only been used clinically for 30 months, so a need exists to further evaluate its toxicity. We report a case of grade Ⅲ (NCI CTCAE v3.0) or grade Ⅳ(SWOG toxicity criteria) paralytic ileus in a 65-year-old man with relapsed multiple myeloma who underwent one cycle of single-agent bortezomib treatment scheduled in a 21-day cycle (1.3 mg/㎥ as a single i.v. bolus on days 1, 4, 8, and 11).

Trigger point를 利用한 口眼괘斜 患者 10例에 대한 臨床的 考察

鄭榮敦,李浚龜,金永一,朴泰均,辛泳一,黃載然,李賢,李秉烈 대전대학교 한의학연구소 2002 한의학연구소 논문집 Vol.10 No.2

From July 1th 2001 to October 31th 2001, the Clinical investigation studies were carried out 10 cases of patient with Bell's palsy using Trigger point treatment group, who had been treated in Han-seung Oriental Medical Clinic. The results were like below : 1. The distribution of sex : Male were 4cases, female were 6case and the female to male ratio was 1.5 : 1. 2. The distribution of contributing factor : Unknown reason was most predominant 4 cases, and then were revealed to labor too hard, menttal stress(3 cases), trauma·common cold(1 case) in turn. 3. The distribution of perid to fall ill : Under a week was the most number 6cases, and then were revealed a week under two weeks(3 cases), over two weeks(1 case) in turn. 4. About period of treatment : The Trigger point treatment group is shorter than the Acupuncture treatment group. 5. The distribution of grade on admission in descending order : GrⅠ was the most number and then GrⅡ, GrⅢ in turn. 6. The distribution of clinical symptoms on adimission : Mastoid pain was the most number 9 cases and then lacrimal gland disorder 8 cases, dysgeusia 4 cases, hyperacusis 2 cases, the others 2 cases in turn. 7. About effect of treatment : The Trigger point treatment group is more excellent than the Acupuncture treatment group. 8. The more patient age is young, the more effect of treatment was excellent, had nothing to do with both groups. 9. The more perid to fall ill is short, the more effect of treatment was excellent, had nothing to do with both groups. 10. About period of improved frontal belly : The Trigger point treatment group is more excellent than the Acupuncture treatment group.

흰쥐에서 사염화탄소에 의해 유도된 간 상해에 미치는 키토산 올리고당의 영향

이영돈,박승림,강소영,김세재,박지권,고영환 제주대학교 생명과학연구소 1999 제주생명과학연구 Vol.2 No.-

Chitosan is the deacetylated product of chitin. Chitosan and its derivatives have many properties that make them attractive for a wide variety of health applications. We reported recently that water soluble chitooligosaccharides have hepatoprotective effect on ethanol induced liver injury in the mouse. The current study examined the effect of water soluble chitooligosaccharides on CC1₄-induced liver injury in rats. Male Sprague-Dawley rats were orally treated with CC1₄without or with administration of 5% chitooligosaccharides. After 5 weeks after CC1₄treatment, the histological sections and the expression of mRNA of interleukin-12(IL-12), hepatocyte growth factor(HGF), and tumor necrosis factor(TNF- ) were examined. The liver section of rats supplemented with chitooligosaccharides showed attenuated effects of the necrosis, steatosis, cirrhosis compared with those of non-supplemented rats. The level of TNF- mRNA in CC1₄-treated rats were higher than those in the rats supplemented with chitooligosaccharides, while the levels of IL-12 and HGF mRNA were higher in the rats supplemented with chitooligosaccharides than those of in CC1₄-treated rats. These findings suggested that water soluble chitooligosaccharides may have a hepatoprotective activity against CCl₄-induced liver injury in rats.

융모성림프구를 보이는 비장변연부 림프종 1예

진한영,손창학,주영돈,박정하,이재익,조영완,이원식 인제대학교 2006 仁濟醫學 Vol.27 No.-

Splenic marginal zone lymphoma is very rare B-cell lymphoma, characterized by an indolent clinical course. Clinical features are moderate-to severe splenomegaly, absolute lymphocytosis, and bone marrow intrasinusoidal infiltration of lymphocyte. We report the case of a 37-year-old male with SMZL. He complained of LUQ pain, who had a massive splenomegaly and moderate lymphocytosis in peripheral blood. Immunophenotyping findings and morphologic findings were consistent with SMZL. He underwent splenectomy and received chemotherapy with cyclophosphamide for eight months. Now, one year later after surgery he has a nearly normal blood count with no treatment.

Hemingway 文學의 暴力

呂永墩 대구효성가톨릭대학교 1984 연구논문집 Vol.29 No.1

The purpose of this study is to eamine the ways in which Ernest Hemingway made artistic use of various kinds of violence in his work. There is a consciously manipulated progression in his use of violence and an understanding of this progression is necessary if Hemingway is to be evaluated objectively as a writer. I maintain that Hemingway moved from an initial concern with the simplest form of violence to an enduring interest in the most complex forms of violence and that this development was the product of a conscious artist who maintained careful control of his material through his writing career. Many critics mention the existence of violence in Hemingway's Work, but none but Phillip Young seem to come to terms with violence as an integral, artistically functional, and meaningful part of Hemingway's ficition. Many critics talk about Heminway's obsession with death and he wrote about violence because he was a violent man. Young's theory of the traumatic neurosis fails to explain the existence of a progressively more sophisticated use of violence as Hemingway matures. My disagreement with Young is that I believe Hemingway controlled the violence that became the material of his art. I oppose Frohock's contention that Hemingway's use of violence was formless and haphazard. This study sets up three kinds of violence: physical violence, verbal violence and violence of self-aggression. Physical violence is the result of the individual's attempting to come to terms with an external, physical enviornment which is hostile or indifferent. A waiter gored by the heedless horns of a pseudo bull, an American ambulance officer in the Italian army having his leg wounded by an Austrian artillery shell, and a Key West man being shot in the stomach are examples of physical violence in Hemingway's work. Verbal violence is the result of the individual attempting to come to terms with others in relation to himself. For lovers and married people it is all too familiar. The weapon emplolyed is spoken word and the damage done is often more irreparable than that inflicted physically. In Hemingway's work love, fraternity, and comradeship are the human conditions within which acts of verbal violence take place. The bitchiness of a wife toward her husband, the frighteningly cruel monologue of a writer attempting to justify the failure of another of his human relations, and the clinical recitation of what the oder of death to come is like are examples of verbal violence in Hemingway's work. Violence of self-aggression is the result of the individul's trying to understand himself. Acts of this kind of violence are often imbued with irony and usually take place in isolation. These are acts of rending and destroying which partake neither of the physical nor the verbal method but are accomplished introspectively and lead to resignation and impotency and often end in selfdestruction. The obsessive concern about a cramped left hand by an old fisherman and a man resigned to death in life and a cardiac case who overexerts himself with purpose are examlpes of violence of self-aggression. Hemingway'sscious investigation of vioence found a focal point in the matter of style of existence. Hemingway uses violence as a metaphor. Violence functions as an artistic means to express a condition of life. The violence in Hemingway's fiction is rarely meaningless, glorified, of without reason, It is violence used as an organic element of the work of art, violence as metaphor, and it serves to reinforce and clarify the progressively more complex and more sophisticated view of life that Hemingway developed and had to come to terms with.

海女漁場紛糾 調査硏究 : 海女入漁慣行의 實態와 性格分析을 中心으로 Their Fishing Practice and Its Characteristics

金斗熙,金榮敦 제주대학교 1982 논문집 Vol.14 No.1

(1) 2萬數千에 이르는 濟州 海女는 世界的 存在다. 이 세상에는 韓國과 日本에만 海女가 있는데, 海女의 本據地는 제주도다. 海女들은 근래 激滅되어 가므로 海女에 대한 調査 硏究는 퍽 시급하지만 아직 큰 進展이 없다. (2.1) 海女들은 漁場을 물에 있는 밭의 延長으로 觀念한다. 漁場을 밭과 꼭 같은 生計를 위한 作業道場으로 생각하기 때문에 海女들은 바다를 마치 집안처럼 친숙하게 여긴다. 第 1種共同漁場이라고도 하는 海女漁場은 마을단위로 나누어지는데, 마을에 따라서는 동네마다 나누어지기도 한다. (2.2) 원래 海女들의 入漁는 國家法이나 行政官廳의 간여없이 慣行에 따라 이루어져 오다가 1962년부터 水産業協同組合法이 제정, 시행됨에 따라, 漁材契가 어촌부락딘위로 조직되고 共同漁業權을 행사하고 있다. 海女들의 入漁權, 入漁時期, 採取物 採取, 收益 分配方法 등에 따른 統制는 潛嫂會 (海女會 )가 맡고 있다. (3.1) 제주도내의 漁場紛糾는 마을과 마을 사이 (혹은 동네와 동네 사이 )의 漁場區劃에 대한 紛爭이 대부분이다. 필자들은 다음의 다섯마을을 대상으로 入漁慣行과 그 紛糾를 조사했는데 A,B,C는 그 분규가 심했던 마을이다. A. 北濟州郡 翰京面 龍水里 B. 北濟州郡 舊左邑 終達里 C. 北濟州郡 舊左邑 演坪里(소섬) D, 北濟州郡 涯月邑 涯月里 E, 北濟州郡 朝天面 北村累 위 A,B,C 마을을 통한 紛糾의 공통점을 간추리면 다음과 같다. 첫째 漁場紛糾의 發生은 社會經濟事情의 變化에 따라 종래의 共同體的 秩序意識이 무너져가는 한 斷面이라 볼 수 있다. 둘째 예전에 비하여 海藻類의 商品價値性이 드높아져 감에 따라 排他的 利權意識이 일어 漁場紛糾가 激甚해졌었다. 근래 이르러서는 미역의 債格이 暴落하고 正確한 漁湯圖에 따른 入漁가 이루어지기 때문에 그 분규는 거의 사라졌다. 세째 그 漁場紛糾의 실마리는 대체로 從來의 慣行을 충분히 고려하지 않고 漁場區劃線을 劃定했거나, 共閣入漁區域의 分割을 원만한 合意없이 이루었다는 데 있었다. (3.2) 제주도 해녀들은 約百年前부터 韓半島 各沿海는 물론이요, 日本, 中國, 러시아까지 出稼했다. 그들의 構益을 위해 1956년에는 가장 많은 해녀가 나갔던 慶尙北道 九龍浦·良浦·大甫 三個水協 共同漁場에 제주도 해녀 1,070명이 入漁할 수 있는 入漁慣行權을 제정받기에 이르렀다. 그러나 그들의 權益收奪은 根絶되지 않음으로써 항상 말썽이 뒤따랐으며 드디어 1967년 慶尙北道側에서는 慶北裁定地區에 出稼하는 제주 해녀들에 대한 '入漁慣行權 消滅確認請求訴訟'을 제기하기에 이르렀다. 이 訴訟事件은 큰 波紋을 던지면서 이어졌거니와 그 동안에도 줄곧 海女出稼는 계속되어 갔다. (4.1) 海女의 入漁慣行은 權利이냐, 또는 法의 反射的 作用이냐를 두고 많은 論難이 거듭되어 왔다. 入漁慣行은 일종의 物權的 權利로 보는 것이 타당하다. (4.2) 海女들의 入漁慣行도 나날이 變化하는 社會經濟的 事情에 따라 변모되지 않을 수 없다. (5.1) 근래 이르러 도내에서의 慣行入漁는 사실상 보호 받고 있어서 이로 말미암은 法的是非는 거의 없다. 다만 아직도 韓半島에는 제주 해녀들이 出稼하고 있으며 이들에 대한 權益保護는 遼遠한 실정이므로 水産業法이 改正돼야 하는 등 충분한 대책이 세워져야 할것이다. (5.2) 出稼海女에 대한 客主나 現住民의 收奪을 방지하기 위하여 出稼海女의 慣行入漁에 따르는 諸般義務를 法令으로 규정하는 것이 타당하며, 共同漁場에의 潛水器船 侵入을 철저히 規制하기 위한 확고한 대책이 마련되어야 할 것이다. Twenty five thousand odd women divers In Jeju Island arouse worldwide interest. Only two nations, Korea and Japan, have women divers in the world, but their base of operations is Jeju Island. Because the young girls In feju Island don't want to become women divers any more, the number of women divers grow smaller and smaller day by day. Therefore, the analysis and research on women divers' problems must be conducted without delay. Women divers look upon fishing grounds as the extention of a field on the land. And they think fishing grounds to be working places only for their livehood so that they regard the sea as their intimate home. Women divers' fishing grounds are divided according to units of local communities, or in some other cases according to those of neighborhood. By nature, women divers' fishing had been done according to the havitual practice without the assitance of government or laws, have been consitued as a unit of each fishing village and have exercised their common fishing rights since 1962. The local fishermen's association and the divers' group (women divers' association-) jointly take charge of the fishery rights, the regulation of the fishing season, harvest of the products, as well as the method of division of these products, etc. The troubles over fishing grounds have resulted in then over the divisions of fishing grounds among local communities, or villages. We investigators, inquired the habitual fishing practices and the complications. Villages, A, B and C, are the ones in which the serious troubles over fishing grounds have aroused and villages, D and C, are the ones where such troubles have never been broken out. A. Youngsu Ri, Hankyeong Meon, Bukjuje Gun. B. Jongdal Ri, Guiwa Eub, Bukjeju Gun. C. Yeongpyeong Ri, Gujwa Eub, Bukieiu Gvn. D. Aeweol Ri, Aeweol Eub, Bukjeju Gun. D. Bukchon Ri, Jocheon Meon, Bukjeju Gun. The common issues of such troubles in the case of above A, B and C villages are as follows: First, the outbreak of the troubles over fishing grounds can be considered as the breakdown of the people's consciousness of order, caused by the change of the conditions of social economy. Second, as the commercial value of marine plants had been going up, the consciousness of the rights and interests had become very strong so that the troubles had become acute. Recently most of the troubles have disappeared because the price of brown seaweeds has declined heavily and fishing had been done be abiding by the correct boundaries of fishing grounds. Third, the immediate cause of the troubles over fishing grounds was that the boundary lines had been demarcated without enough consideration of habitual practice heretofore, or that the division of common fishing areas had been made without satisfactory agreement. Women divers in Jeju Do had done fishing at the coasts of Japan, China and Russia, not to mention at the coast along the Korean penninsular. One thousand and seventy women divers in Jeju Island were given the legal right to fishing in common fishing grounds under the control of the following three fishery cooperations: Kuryongpo, Yangpo and Daebo in Kyungsang Pukto, where the more women divers of Jeju Island did their Asking in 1956 than any other time. But many problems about their rights and interests has taken place. Therefore, the Government of Kyungsang Puk Do took legal proceedings against the existing habitual practice of the fishing rights in 1967. It created a great stir for a long time. It is reasonable to regard women divers' Asking habitual practice as a kind of the real right jus in rem. But even this habitual practice must be changed as the conditions of the social economy are changing day by day. Recently they received the proper protection in the case of the habitual fishing practice in Jeju Do. Consequently, there are few legal disputes. But even thesedays, women divers in Jeju Island go and do fish along the coast of Kyungsang Puk Do, etc; therefore, their rights and interests must be protected perfectly. And a permanent counterplan and legislative system must be divised in order to thoroughly probit fleets equipped with diving apparatus from frequenting common fishing grounds.

Polystyrene composites containing crosslinked polystyrene-multiwalled carbon nanotube balls

Kwon, Soon-Min,Kim, Hun-Sik,Kim, Don-Young,Yun, Young Soo,Jin, Hyoung-Joon Wiley Subscription Services, Inc., A Wiley Company 2008 Journal of applied polymer science Vol.110 No.6

<P>Crosslinked polystyrene-multiwalled carbon nanotube (PS-MWCNT) balls, which act as conductive microfillers, were prepared by the in situ suspension polymerization of styrene with MWCNTs and divinyl benzene (DVB) as a crosslinking agent. The diameters of the synthesized crosslinked PS-MWCNT balls ranged from 10 to 100 μm and their electrical conductivity was about 7.7 × 10<SUP>−3</SUP> S/cm. The morphology of the crosslinked PS-MWCNT balls was observed by scanning electron microscopy and transmission electron microscopy. The change in the chemical structure of the MWCNTs was confirmed by Raman spectroscopy and Fourier transform infrared spectroscopy. The mechanical and electrical properties of the PS/crosslinked PS-MWCNT ball composites were investigated. It was found that the tensile strength, ultimate strain, Young's modulus, and impact strength of the PS matrix were enhanced by the incorporation of the crosslinked PS-MWCNT balls. In addition, the mechanical properties of the PS/crosslinked PS-MWCNT ball composites were better than those of the PS/pristine MWCNT composites. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008</P>

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

68세 여자에서 발견된 Morgagni hernia 1예

정영일,정귀예,민영돈,김경종 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.3

Morgagni hernia is a herniation of abdominal viscera into the thoracic cavity through the sternocostal hiatus (foramen of Morgagni). It has the lowest occurrent rate of 3% among congenital diaphragmatic defects. Generally, the defect is present from the early embryonic period without apparent symptoms, but symptoms can occur with the defect growing in size in adult. We report a case of Morgagni hernia complaining of intermittent RUQ abdominal pain in 68-year-old women. In addition, we considered other related references with our case.