전염성 단핵구증 1예

이종수,김도영 梨花女子大學校 醫科大學 醫科學硏究所 2001 EMJ (Ewha medical journal) Vol.24 No.3

Infectious mononucleosis is an acute lymphoproliferative disease that is most common in children and young adults and is caused by Epstein-Barr virus. Characteristic clinical feastures include : 1) fever, sore throat, and lymphadenopathy ; 2) an associated absolute lymphocytosis greater than 50%, of which at least 10% are atypical lymphocytes in the peripheral blood ; 3) development of transient heterophil and persistent antibody responses against Epstein-Barr virus ; and 4) abnormal liver function tests. The most prevalent age of infectious mononucleosis in Korea was less than 5 years old and it has been very rare in adulthood. However, recently in Korea, possibly due to the increasing number of people who are non-immune to Epstein-Barr virus, the age range seems to be increasing from young childhood to over 10 years old and even to adulthood. We present a 19-year-old man who showed typical clinical features of infectious mononucleosis.

후두부 발작성 간질파와 동반된 양성 소아기 간질의 임상적 연구

유영수,이상도,김지언,임정근,박영춘 대한신경과학회 1996 대한신경과학회지 Vol.14 No.4

GTP cycohydrolase Ⅰ이 Tyrosine Hydroxylase의 활성, 발현 및 세포의 성장에 미치는 영향

이영재,한인숙,이상도 대한신경과학회 1999 대한신경과학회지 Vol.17 No.1

소듐-물 반응사고 중/후반기 계통거동특성 연구

정지영,어재혁,김태준,정경체,김병호,한도희,박남국 한국공업화학회 2004 응용화학 Vol.8 No.1

In order to investigate the later phase of a sodium-water reaction (SWR) event in KALIMER (Korea Advanced Liquid MEtal Reactor), the code SELPSTA (Sodium-water reaction Event Later Phase System Transient Analyzer) has been developed and an experimeantal study has been carried out for verification of the simple analysis model applied to the code. The 24 data set obtained in the experiment have been pre-analyzed. Comparison of SELPSTA results with experimental data shows fairly good agreement in the transient.

간질환자에서 장기간 항 경련제 치료시 뇌간청각유발전위의 변동

박영춘,이동국,임정근,이상도,이형 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.2

저자들은 만성적인 항경련제 투여가 간질환자들의 청신경계에 미치는 영향을 조사하기 위하여 장기간(12개월 이상)항경련제를 복용한 간질환자 51례를 대상으로 이학적 진찰 및 BAEP검사를 실시하고 정상인의 성적과 비교하여 다음과 같은 결과를 얻었다. 장기간 항경련제를 복용한 간질환자의 BAEP검사의 평균 절대 및 파간잠복기는 대조군과 비교하여 유의한 차이가 없었다. Phenytoin단독투여군의 절대 및 파간잠복기는 대조군에 비해 유의한 차이가 없었다. Carbamazepine단독투여군의 I-III파간잠복기는 대조군과 phenytoin단독투여군에 비해 유의하게 연장되었다(p 0.01). Phenytoin단독투여군과 carbamazepine단독투여군에서 항경련제의 복용기간과 BAEP의 절대 및 파간잠복기사이에는 유의한 관계가 없었다. Phenytoin단독투여군과 phenytoin병합투여군에서 각파의 절대 및 파간잠복기는 서로 유의한 차이가 없었다. 이상의 결과로 볼 때 장기간 항경련제를 복용한 간질환자에서 BAEP의 평균 절대 및 파간잠복기는 정상대조군과 비교하여 유의한 차이가 없었고, 항 경련제의 복용기간에 따른 절대 및 파간잠복기의 유의한 변화가 없는 것으로 생각되었다. This study was performed to verify whether or not chronic anticonvulsansts therapy(≥12 months) is associated with brainstem auditory pathway dysfunction in epileptics. Brainstem auditory evoked potentials were done to 51 epileptics who had been taking long term anticonvulasant. The results were summarized as follows. The mean absolute and interpeak latencies were not significantly different between epileptics and controls. The mean absolute and interpeak latencies were not significantly different between epileptics with phenytoin monotherapy and controls. The mean Ⅰ-Ⅲ interpeak latency of carbamazepine monotherapy was significantly delayed than that of phenytoin monotherapy or controls. There was no significant relationship between latency of BAEP and duration of therapy with either phenytoin or carbamazepine. In epileptics with phenytoin combined therapy, the mean absolute and interpeak latencies were not significantly delayed than those of phenytoin monortherapy.

장기간 항경련제 투여 환자에게서의 신경전도 속도

박영춘,이동국,임정근,이상도,이형 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

This study was performed to verify whether or not chronic anticonvulsants therapy(≥12 months ) is associated with peripheral nerve dysfunction in epileptics. Nerve conduction studies were done to 51 epileptics who had been taking long term anticonvulsants therapy over 12 months. The mean age of epileptics was 23 years, and was composed of 29 men and 22 women. The mean nerve conduction velocity(NCV) was not significantly different between epileptics and controls. Compared phenytoin or carbamazepine monotherapy group with controls, the NCV was not significantly different in two groups respectively. In epileptics, the mean NCV was not significantly different between phenytoin and carbamazepine monotherapy group. There was no significant relationship between NCV and duration of therapy with either phenytoin or carbamazepine. In epileptics with phenytoin combined therapy, the mean median sensory NCV was significantly delayed than in those with phenytoin monotherapy.

한번의 간질발작 후 혈청 Neuron-Specific Enolase 농도 변화

최승호,박영춘,이장준,임정근,김지언,이상도 啓明大學校 醫科大學 1999 계명의대학술지 Vol.18 No.4

An increase in neuron-specific enolase (NSE) levels in serum and CSF has been shown to be an useful marker of brain damage after stroke, global ischemia, and coma. We report the changes of serum NSE levels after seizure attacks in epileptic patients compared with the levels in normal controls and epileptic patients without seizure attack at least 7 days (epileptic controls). Twenty-four seizures were included in this study. Blood was drawn within 1 hour, at 12 hour, 24 hour, and 48 hour after seizure attack. Serum NSE levels were measured with radioimmunoassay. The mean NSE levels for normal controls and epileptic controls were 6.94 ng/ml and 7.46 ng/ml, respectively. There were significant increase in level of serum NSE measured within 1 hour after seizure attack in epileptics compared with the level in normal controls (15.10ng/ml versus 6.94ng/ml, p<0.05) and epileptic controls (15.10ng/ml versus 7.46ng/ml, p<0.05). Serum NSE measured at 12 hours after seizure also increased compared with normal controls (12.32ng/ml versus 6.94ng/ml, p<0.05) and epileptic controls (12.43ng/ml versus 7.46ng/ml, p<0.05). Between normal controls and epileptic controls, there were no significant difference in serum NSE levels. We conclude that serum NSE level was elevated in epileptic patients who had seizure attack within 12 hours. Serum NSE levels can be useful marker for seizure within 12 hours after onser. The elevated serum NSE level after single seizure attack may suggest that the brain was injured in single seizure.

석회유담즙증 1예

이지아,김도영,정혜경,문일환,신수연,곽재진 梨花女子大學校 醫科大學 醫科學硏究所 2003 EMJ (Ewha medical journal) Vol.26 No.1

Milk of calcium bile or limy bile is a rare disorder in which the gallbladder lumen is filled with a thick, paste-like, radio-opaque material. Churchman first reported a case of curious deposition of calcium salts within the gallbladder in 1911. Volkmann first used the term Kalkmilchgalle or "milk of calcium bile" in 1926. The radio-opaque material is almost entirely composed of calcium carbonate by weight. The mechanisms by which bile turns limy and radio-opaque or the time required for this biochemical alteration to occur are not well understood. The limy bile is found mostly in a gallbladder complicated by cholecystitis. Recently, we experienced a 33 year old woman who had a milk of calcium bile in the gallbladder lumen. We report this case with a review of literature.

췌장의 점액성 낭선암 1예

송현주,김도영,정혜경,남승현,문일환,구혜수 梨花女子大學校 醫科大學 醫科學硏究所 2002 EMJ (Ewha medical journal) Vol.25 No.2

Nowadays increasing use of abdominal ultrasound in routine check-up may increase the detection rate asymtomatic cystic lesions of pancreas. Even through the majority of the cystic lesions of pancreas is pseudocyst, about 10-15% of those lesions are caused by pancreatic cystic tumor. In the pancreatic cystic tumor, especially, mucinous cystic tumor should be exicised due to its malignant potential, while the pancreatic pseudocyst or serous cystic tumon can be observed for a period or treated medically. Several clinical, radiological, biochemical and pathologic guidelines have been developed in order to distinguish among them. Among pancreatic cystic tumors, mucinous cystic adenocarcinoma is very rare and accounts for only 1% of all pancreatic neoplasms. Unlike extremely poor prognosis of pancreatic adenocarcinoma, mucinous cystic adenocarcinoma has an indolent course and shows a good prognosis after its curative resection. Recently we experienced a 69-year-old woman who had a mucinous cystic adenocarcinoma of the pancreas. We report this case with a review of literature.

교근과 이하선 및 하악골에 발생한 횡문근 육종의 치험례

정수일,박재범,이계영,김도균,안재진 大韓顎顔面成形再建外科學會 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.1