반복적인 급성 신부전을 유발한 호산구성 장염 1 예

정혜진;김현태;김유선;정현걸;강윤경;문정섭 인제대학교 2011 仁濟醫學 Vol.32 No.-

Eosinophilic gastroenteritis is a rare disorder of unknown etiology characterized by presence of gastrointestinal symptoms, eosinophilic infiltratio n of one or more parts of gastrointestinal tract without involvement of other organs and absence of parasitic infestation. The clinical presentation depends on the extents and depths of eosinophilic infiltration. Mucosal involvement may result in abdominal pain, nausea, vomiting, diarrhea and weight loss. We report a case of eosinophilic enterocolitis in a 55-year-old female presented with abdominal pain and watery diarrhea resulting in recurrent acute renal failure.

응집제 Ceramic-Zeolite type과 황토를 이용한 Microcystis aeruginosa 제거에 관한 연구

박홍기,정은영,이유정,정종문,최식영,홍용기 한국환경과학회 2002 한국환경과학회지 Vol.11 No.4

For the proposal of Microcystis aeruginosa control technique by coagulants, removal effects of coagulants were carried out using isolated strain and collected water bloom of M. aeruginosa on Downstream of the Nakdong River. Both of purified and field-collected M. aeruginosa were entirely sedimented by the addition of the coagulant Ceramic-Zeolite type Co 100 (1.5 mg/l) within 24 hr, but Yellow loess (10 mg/l) was less effective for the removal of M. aeruginosa within 24hr. Thus it was concluded that Ceramic-Zeolite type Co 100 was the most effective coagulant.

유용성 도료와 수용성 도료의 유해성 비교에 관한 연구 : 자동차 보수용 도료를 중심으로

권은혜,김광식,오정룡,최정근,정윤석,이유진,김은아,송세욱,정호근 한국산업위생학회 2001 한국산업보건학회지 Vol.11 No.1

The purpose of this study is to substitute water-based painting materials for the current solvent-based ones used in motor-repairing process to minimize the exposure of organic solvents to the painters. This study assessed the exposure of organic solvents to the painters using water-based and solvent-based painting materials and compared compositions, painting processes and the health hazards of the application of these alternative painting materials. The results of this study are as follows. 1. solvent-based painting materials used in motor-repairing process consist of various organic solvents, which consist primarily of toluene, xylene, ethyl benzene, ethyl methyl bezene, trimethyl bezene, ethyl acetate, butyl acetate, methyl isobutyl ketone, 2-ethoxy ethanol, 2-ethoxy ethyl acetate and toluene-2.4-diisocianate and the others. These organic solvents are know as health-hazardous substances. But water-based painting materials are high-solid, low-solvent ones and consist of such two organic solvents as 2-butoxy ethanol and 2-heptanone and the others. 2. The painters using solvent-based painting materials in motor-repairing process are exposed to various organic acetate, methyl isobutyl ketone, trimethyl benzene, 2-ethoxy ethanol, and 2-ethoxy ethyl acetate. But the painters using solvent-based ones are only exposed to 2-butoxy ethanol and 2-heptanone. 3. By using water-based painting materials in stead of solvent-based painting materials containing health-hazardous organic solvents, the exposure of such organic solvents in the painter's breathing zone can be largely prevented. 4. This study recommends water-based painting materials as substitutes for the current solvent-based ones used in motor-repairing process to minimize the exposure of organic solvents to the painters.

경사로 활동에서의 유아의 연령에 따른 구성놀이 질의 차이

유영의,성정숙 순천향대학교 인문과학연구소 2007 순천향 인문과학논총 Vol.20 No.-

노인 인구에서 신경인지기능저하와 혈청 지질농도와의 상관성

유영선,최석주,정성수,김지은,윤성욱,전동욱,백준형,박성우,이정구,추일한,김영훈 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.6

Objectives : In this study, the authors evaluated the correlation between eurocognitive impairments and serum lipids levels among Korean elderly over the age of 65. Methods : A total of 609 elderly individuals participated in this study. Screening for cognitive impairments were carried out using the Mini-Mental Status Examination-Korean version (MMSE-KC). There were 197 subjects above 1.5SD Of MMSE- KC and they were evaluated using the Korean versions of the Consortium to Establish a Registry for Alzheimer's Disease (AD) (CERAD-KC) and Geriatric Depression Scale (GDS-K). Results : There was a correlation between old age/low levels of education and AD (p<0.05, P<0.01). There was an inverse correlation between the serum level of total cholesterol and the word list recognition test scores. The serum levels of LDL cholesterol were inversely correlated with the scores on the constructional praxis test, word list recall test and word list recognition test. Inverse correlations between the serum level of triglyceride and scores on the word list recall test and word list recognition test were also observed. Conclusion : There were inverse correlations between the serum levels of lipids and language/memory function in subjects with AD.

Dihydroflavonol 4-reductase 유전자를 이용한 담배의 형질전환

유정아,이원숙,이주안,김영채,박영두 경희대학교식량자원개발연구소 2006 硏究論文集 Vol.25 No.-

본 연구는 화색과 관련된 DFR 유전자를 Agrobacterium을 이용한 형질전환 방법으로 담배(Nicotiana tabaccum L.)에 형질전환 시키기 위해 수행되었다. 이를 위하여 배추의 DFR 유전자를 CaMV 35S promotor와 nos terminator를 운반하는 식물 발현용 vector, pCAMBIA 1302에 삽입하였다. 재조합된 벡터 pCAMBIA 1302-DFR은 Agrobacterium tumfaciens LBA4404를 이용하여 담배 식물체 잎 절편체를 형질전환한 후 MS 배지에 1.5 mg·L^(-1) BA, 50 mg·L^(-1) hygromycin 및 200 mg·L^(-1) cefotaxim이 첨가된 1차 선발배지에서 신초를 유도하였다. 유도된 신초는 100 mg·L^(-1) hygromycin과 200 mg·L^(-1) cefotaxim이 첨가된 2차 선발 배지에서 뿌리를 유기하였다. 뿌리가 형성된 재분화 개체는 온실에서 재배하였으며 재배된 담배로부터 genomic DNA를 추출하고 DFR 유전자의 담배 genome내로의 전이여부를 hygromycin primer를 이용하여 PCR 방법으로 확인한 바 형질전환 개체에서 예상했던 365 bp 단편을 볼 수 있었으나 형질전환을 시키지 않은 식물체에서는 PCR 산물을 확인 할 수 없었다. PCR 검정으로 확인된 담배는 화색변이 여부를 관찰하기 위해 온실에서 재배 중에 있다. Dihydroflavonol 4-reductase (DFR) gene was introduced into tobacco (Nicotiana tabaccum L.) plants using Agrobacterium mediated transformation. To introduce this gene, DFR gene was cloned into plant binary vector, pCAMBIA 1302, harboring CaMV 35S promotor and nos terminator. After infection with Agrobacterium tumefaciens LBA4404 containing pCAMBIA 1302, transformed shoots were induced from first selection medium (MS medium + 1.5 mg·L^(-1) BA + 50 mg·L^(-1) hygromycin + 200 mg·L^(-1) cefotaxim). To confirm the transfer of DFR gene in the genome of tobacco plants, PCR was conducted using primers of the hygromycin gene. A PCR fragment of 365 bp was obtained from each transformed plants, which is the predicted size of the hygromycin gene but not from nontransformed plants. Transformed tobacco plants are growing in the greenhouse to analyze phenotypic variation, especially flower color.

젠더관점에서의 난자 채취 손해배상 청구소송에 대한 검토

이유정 이화여자대학교 젠더법학연구소 2014 이화젠더법학 Vol.6 No.2

이 글은 황우석 박사 연구팀에 난자를 제공한 여성 2명이 국가와 난자채취 시술을 한 병원 2곳을 상대로 손해배상청구소송을 제기한 사건의 1, 2심 판결을 젠더의 관점에서 분석하고 비판하는 글이다. 1, 2심 법원은 모두 (1) 원고들이 자발적인 의사에 의해 난자를 제공하였고,(2) 사전에 시술의 부작용이 고지되었기 때문에 병원은 설명의무를 다하였다는 이유로 원고 패소 판결을 선고하였다. 위 판결에 대해서는 젠더 관점에서 다음과 같은 문제를 제기할 수 있다. (1) 원고들이 난자를 제공한 이유는 기망 또는 강압에 의한 것으로 볼 여지가 충분하다. (2) 본인에게 아무런 이득이 없는 연구를 위해 임상실험의 대상이 되는 경우는 더 높은 정도의 자기결정권이 보장되어야 하며, 더 높은 수준의 정확하고 충분한 정보가 제공되어야 한다. (3) 난자채취가 여성의 신체에 미치는 영향이 매우 크기 때문에 시술의 부작용과 위험성에 대한 충분한 설명이 있어야만 한다. (4)난자채취로 인한 정신적?신체적인 증상은 손해로 인정되어야 한다. (5) 여성들이 난자를 제공하는 이면에는 여성에게 억압적이고 차별적인 사회·문화·정치적인 배경이 존재하므로 이러한 점을 감안하여‘자발성’을 판단해야 한다. (6) 자발성이 있다는 이유만으로 난자제공 및 난자를 이용한 실험이 무제한 허용되어서는 안 된다. 이 판결은 생명공학 기술의 발전과 젠더의 문제에 대해 많은 시사점을 제공한다. 앞으로 생명공학의 연구와 적용과정에서 나타나는 여성의 구체적인 경험을 법이론으로 만들어내는 노력이 필요할 것이다. This article analyzes and criticizes from the perspective of gender the court rulings of the first and second trials in the case where two women, who donated eggs to Professor Hwang’s research team, filed a compensation claim against the government and 2 hospitals where the eggs have been extracted. For both instances, the court ruled against the plaintiffs because (1) the plaintiffs donated the eggs voluntarily and (2) the side effects of the surgery had been informed beforehand. From a gender perspective, the rulings above may raise the following issues: (1) There is sufficient evidence to view that the plaintiffs provided the eggs due to fraud or coercion. (2) In cases where a woman is the subject of a clinical demonstration for a study that does not directly benefit her, a higher degree of self-determination should be guaranteed, and she should be provided with adequate and more accurate information. (3) There should be sufficient explanation of the side effects and the risks of the surgery since collection of eggs is a medical surgery that has a very large impact on the female body. (4) The physical/mental symptoms due to collection of eggs should be considered as a loss. (5) The ‘voluntariness’ of the two plaintiffs who donated the eggs should be judged by taking into account the presence of the oppressive and discriminatory social, cultural, and political background in Korea. (6) The existence of willingness should not allow for the donation of eggs or the unlimited experiments using eggs. This court decision provides a number of implications for gender issues in relation to the development of biotechnology. There should be efforts to create legal theories regarding the specific experience of women in the research and the application process of biotechnology.

유구치 상아질의 각 부위에 적용된 수종의 복합레진 접착제의 미세인장접착강도에 관한 연구

유정은,최영철,최성철,박재홍 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.3

본 연구는 유구치 상아질의 각기 다른 부위(표층부, 심층부, 치경부)에서 복합레진 접착제의 접착강도를 비교, 평가하기 위하여 임상에서 흔히 사용하고 있는 서로 다른 4종의 접착방식(3-step total etch: 1군, 2-step total etch: 2군, 2 step self-etch: 3군, all-in-one: 4군)을 적용하고 복합 레진(Light-Core™ Core Build-Up Composite)을 적층한 후, 미세인장접착강도를 비교하였을 때 다음과 같은 결과를 얻었다. 1. 접착방식간의 비교에서 레진의 접착방식에 따른 상아질 각 부위에서의 미세인장접착강도는 제 1군이 표층부에서 뚜렷이 높았으나(p<0.05) 2, 3, 4군은 부위에 따른 차이가 없었다. 2. 부위별 미세인장접착강도를 비교하여 보았을 때 상아질 표층부에서의 미세인장접착강도는 레진의 접착 방식간에 차이가 없었으나, 심층부에서는 2군, 3군, 4군 및 1군의 순으로 나타났고(p<0.05), 치경부에서는 2군과 3군이 1군과 4군에 비하여 현저히 높았다(p<0.05). The purpose of this study was to evaluate the micro-tensile bond strength (μTBS) of four luting resin to regional dentin of human primary teeth. Dentin from non-carious primary molars were prepared from different regions(s, superficial dentin; d, deep dentin; c, cervical dentin), and divided into groups based on anatomical locations and types of luting resins(Scotchbond Multi-purpose: SB ; One-Step: as ; AdheSE Bond: ASE ; G-Bond : GB) : SB-s, SB-d, SB-c; OS-s, OS-d, OS-c; ASE-s, ASE-d, ASE-c ; GB-s, GB-d, GB-c. Luting resins were used according to the manufacturers' instructions, to bond Light-Core™ Core Build-Up Composite) to the exposed dentin specimens in the light-curing mode. After storage for 1 day, μTBS was tested at a cross-head speed of 1 mm/min. Data were analyzed with T-test and two-way ANOVA. The bonding interface and fractography analyses were performed with SEM. The results were as follows : 1. μTBS to superficial dentin was significantly higher than to deep dentin for SB(p<0.05). But there were no significant differences in regional μTBS among as, ASK GB(p>0.05). 2. There were no significant differences in μTBS to superficial dentin among each groups. But, in deep dentin, μTBS of SB-d was significantly lower than those of OS-d, ASE-d, and GB-d(p<0.05). μTBS of OS-d was significantly higher than those of GB-d(p<0.05), but there were no significant differences in μTBS of ASE-d. There were no significant differences among μTBS of ASE-d, OS-d, and GB-d.

환경 친화적 Bi-황동의 응력부식균열에 관한 연구

劉承宰,崔允碩,金正九 대한금속재료학회 2002 대한금속·재료학회지 Vol.40 No.6

The purpose of the present investigation was to study the stress corrosion cracking (SCC) properties of environmentally friendly Bi-brasses in Mattsson's solution (0.05M copper sulfate and 0.5M ammonium sulfate, pH 7.4) at room temperature. Three unleaded brasses with Bi content ranging from 1 to 3 wt% and a conventional leaded brass for comparison were investigated. The effect of Bi on SCC of unleaded brasses was studied through polarization test, electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM, energy dispersive spectroscopy (EDS) and slow-strain-rate test (SSRT). Potentiodynamic polarization studies indicated that the corrosion resistance of Bi-containing brasses was improved as the content of Bi, which showed a passivating characteristic in Mattsson's solution, increased. The Pb- and Bi-containing brasses presented an inductive behavior on impedance data in low frequency region at the open-circuit potential (OCP). Such behavior could be attributed to the adsorption process on the alloy surface. The observed dezincified layers after SSRT should be particularly good initiators of SCC as they could induce tensile stress. As the content of Bi increased, the thickness of dezincified layer and the volume fraction of preferentially attacked Β phase decreased, therefore, SCC resistance of the Bi-containing brasses was improved.

사회성 훈련 프로그램이 발달장애아동의 사회성 및 적응행동에 미치는 효과

유은희,양정남,이숙자 동신대학교 2005 論文集 Vol.15 No.-

The Effects of a Social Skills Program on Improving Sociability, and Adaptive Behaviors of Children with Developmental Disabilities. The purpose of this study was to investigate the effects of a social skills program on improving social skills, and adaptive behaviors of children with developmental disabilities. A total of nine children at the Language Therapy Center for children and adolescents in Gwangju Metropolitan City participated in this study with the consent from their parents. The research was conducted following one-group pretest-posttest design, a preexperimental design. A social skills program was implemented once a week with 90 minutes per session for 15 weeks. The effects of the program were evaluated by administering Social Maturity Scale, and Adaptive Behavior Scale before and after the program. The results showed that the scores in social maturity, and adaptive behavior scales, respectively, increased from pretest to posttest. This study concluded with a discussion on the implications of social skill programs for improving social skills, and adaptive behaviors of children with developmental disabilities in the field of social welfare. Implications and suggestion for future studies was discussed.