http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Yoonhwa Jeong 한국식품영양과학회 2011 Preventive Nutrition and Food Science Vol.16 No.2
The purpose of this study was to elucidate the physicochemical and microbiological properties of Korean traditional rice wine, Makgeolli, supplemented with black garlic extract during fermentation. Black garlic extract was diluted with distilled water to produce 0.5% and 1.0% black garlic solutions. Those solutions were then used to make rice solutions which included 2 ㎏ rice, 40 g Nuruk (a fermentation starter), and 14 g yeast. After being mixed, the rice solutions were fermented for 7 days in a water bath at 28℃. The alcohol contents of the control, 0.5% and 1.0% black garlic Makgeolli were 16.9, 16.0, and 16.2%, respectively. Total acidity, total soluble solids, and color increased throughout the fermentation process. There was an increase of microorganisms throughout the fermentation period in all the samples. Glucose was the highest free sugar, and succinic acid was the highest organic acid detected in all the samples. Thirty nine volatile compounds were detected in black garlic Makgeolli.
Yoonhwa Jeong,Eul-Sang Kim,Mi-Hyoun Park,Sung-Joo Hwang,김미숙 한국식품영양과학회 2004 Journal of medicinal food Vol.7 No.2
Saengshik is a Korean “non-cooked food” that is commercially produced and marketed. Ingredients in com- mercial Saengshik include grains, vegetables, fruits, mushrooms, sea plants, and various functional botanicals. This study in- vestigated the effects of Saengshik on the survival rate of streptozotocin (STZ)-induced diabetic rats. Male Sprague-Dawley rats weighing around 190 g were randomly assigned to one of the three experimental groups: a healthy normal group (NC) and two groups with STZ-induced diabetes and fed either control diet (DC) or Saengshik diet (DS). Rats in all groups were supplied with a diet of equal energy. The animals were maintained on an experimental diet for 168 days in experiment I and for 42 days in experiment II. The body weight in the DS rats decreased less than in the DC rats in both experiments I and II. There was a trend for blood glucose level in the DS group to decrease during the experimental period in both experiments I and II. A survival rate of 50% was reached on day 49 in the DC group and on day 118 in the DS group. All rats in the DC group died by day 140, while 50% of the rats in the DS group were still alive on day 168, when experiment I was terminated. In experiment II, 50% of the DC group and 90% of the DS group survived at day 42. Saengshik did not have any influence on cholesterol levels, thiobarbituric acid-reactive substances, and activities of superoxide dismutase and glutathione peroxi- dase. These results suggest that blood glucose concentrations and the survival rate are positively affected by Saengshik feed- ing in diabetic rats.
Involvement of PI3K and MMP1 in PDGF-induced Migration of Human Adipose-derived Stem Cells
Yoonhwa Lim,Minji Lee,Hyeju Jeong,Haekwon Kim 한국발생생물학회 2017 발생과 생식 Vol.21 No.2
Human adult stem cells have widely been examined for their clinical application including their wound healing effect in vivo. To function as therapeutic cells, however, cells must represent the ability of directed migration in response to signals. This study aimed to investigate the mechanism of platelet-derived growth factor (PDGF)-induced migration of the human abdominal adipose-derived stem cells (hADSCs) in vitro. A general matrix metalloproteinase (MMP) inhibitor or a MMP2 inhibitor significantly inhibited the PDGF-induced migration. PDGF treatment exhibited greater mRNA level and denser protein level of MMP1. The conditioned medium of PDGF-treated cells showed a caseinolytic activity of MMP1. Transfection of cells with siRNA against MMP1 significantly inhibited MMP1 expression, its caseinolytic activity, and cell migration following PDGF treatment. Phosphatidylinositol 3-kinase (PI3K) inhibitor reduced the migration by about 50% without affecting ERK and MLC proteins. Rho-associated protein kinase inhibitor mostly abolished the migration and MLC proteins. The results suggest that PDGF might signal hADSCs through PI3K, and MMP1 activity could play an important role in this PDGF-induced migration in vitro.
Involvement of PI3K and MMP1 in PDGF-induced Migration of Human Adipose-derived Stem Cells
Lim, Yoonhwa,Lee, Minji,Jeong, Hyeju,Kim, Haekwon The Korean Society of Developmental Biology 2017 발생과 생식 Vol.21 No.2
Human adult stem cells have widely been examined for their clinical application including their wound healing effect in vivo. To function as therapeutic cells, however, cells must represent the ability of directed migration in response to signals. This study aimed to investigate the mechanism of platelet-derived growth factor (PDGF)-induced migration of the human abdominal adipose-derived stem cells (hADSCs) in vitro. A general matrix metalloproteinase (MMP) inhibitor or a MMP2 inhibitor significantly inhibited the PDGF-induced migration. PDGF treatment exhibited greater mRNA level and denser protein level of MMP1. The conditioned medium of PDGF-treated cells showed a caseinolytic activity of MMP1. Transfection of cells with siRNA against MMP1 significantly inhibited MMP1 expression, its caseinolytic activity, and cell migration following PDGF treatment. Phosphatidylinositol 3-kinase (PI3K) inhibitor reduced the migration by about 50% without affecting ERK and MLC proteins. Rho-associated protein kinase inhibitor mostly abolished the migration and MLC proteins. The results suggest that PDGF might signal hADSCs through PI3K, and MMP1 activity could play an important role in this PDGF-induced migration in vitro.
Jung, Yoonhwa,Jung, Jaehoon,Kim, Byungil,Han, SangUk Elsevier 2020 JOURNAL OF CLEANER PRODUCTION Vol.250 No.-
<P><B>Abstract</B></P> <P>The sites selected for solar PV facilities significantly affect the amount of electric power that can be generated over the long term. Therefore, predicting the power output of a specific PV plant is important when evaluating potential PV sites. However, whether prediction models built with data from existing PV plants can be applied to other plants for long-term power forecasting remains poorly understood. In this case, topographical and meteorological conditions, which differ among sites and change over time, make it challenging to accurately estimate the potential for energy generation at a new site. This study proposes a monthly PV power forecasting model to predict the amount of PV solar power that could be generated at a new site. The forecasting model is trained with time series datasets collected over 63 months from 164 PV sites with data such as the power plant capacity and electricity trading data, weather conditions, and estimated solar irradiation. Specifically, a recurrent neural network (RNN) model with long short-term memory was built to recognize the temporal patterns in the time series data and tested to evaluate the forecasting performance for PV facilities not used in the training process. The results show that the proposed model achieves the normalized root-mean-square-error of 7.416% and the mean absolute-percentage-error (MAPE) of 10.805% for the testing data (i.e., new plants). Furthermore, when the previous 10 months’ data were used, the temporal patterns were well captured for forecasting, with a MAPE of 11.535%. Thus, the proposed RNN approach successfully captures the temporal patterns in monthly data and can estimate the potential for power generation at any new site for which weather information and terrain data are available. Consequently, this work will allow planning officials to search for and evaluate suitable locations for PV plants in a wide area.</P> <P><B>Highlights</B></P> <P> <UL> <LI> An LSTM-RNN-based forecasting model is presented for investigation of PV sites. </LI> <LI> Time series data of spatial and meteorological conditions depict input variables. </LI> <LI> Monthly solar photovoltaic power generation at any specific site can be predicted. </LI> <LI> nRMSE of 7.416% is achieved for long-term power prediction of new candidate sites. </LI> </UL> </P>
Ginkgetin induces cell death in breast cancer cells via downregulation of the estrogen receptor
Park, Yoonhwa,Woo, Sang Hyeok,Seo, Sung-Keum,Kim, Hyunggee,Noh, Woo Chul,Lee, Jin Kyung,Kwon, Byoung-Mog,Min, Kyung Nam,Choe, Tae-Boo,Park, In-Chul Spandidos Publications 2017 Oncology letters Vol.14 No.4
허윤화(Hur, Yoonhwa) 한국초등영어교육학회 2020 초등영어교육 Vol.26 No.2
This study aimed to explore the possibility of implementing dynamic assessments using DIBELS (Dynamic Indicators of Basic Literacy Skills) in English classes. It examined the relationships between the reading fluency of the elementary fifth-grade students and their DIBELS scores. Participants were 29 students who took the grade 1-2 tests. The main findings of this study were as follows: First, the participants’ overall scores were above the first-grade benchmark. Also, the tests were able to measure EFL students’ reading fluency by discriminating the phases of alphabetic development with an accuracy of 96.6%. Second, the composite and almost all sub-test scores of the participants showed a high correlation. Furthermore, the composite score explained 80.6% of the participants’ reading fluency. It supports the claim that DIBELS can represent the overall reading fluency of EFL students. Since dynamic assessments can be conducted as a form of curriculum-based measurement, it is preferable to apply them to elementary students in the early stages of reading development. In particular, DIBELS can be conducted several times per year to measure the degree of weakness in students’ reading fluency. Therefore, dynamic assessments will help students who fall behind at a basic reading ability level.