혈뇨의 감별진단을 위한 이형적혈구의 형태학적 연구

윤철종,박정오,문희주,윤기은 韓國電子顯微鏡學會 1999 Applied microscopy Vol.29 No.3

전체 성인의 약 4%에서 정도 차이는 있지만 혈뇨가 있다고 볼 때 그 원인을 구명하는 일이 중요하다. 그 원인이 사구체성 신염인지 기타 그 외의 비사구체성 원인에 따른 질환인지를 쉽게 감별하는 일이 중요하다. 본 연구자들은 혈뇨를 동반한 소아과 환자중에서 신 생검 조직검사까지 한 5명의 환자에서 혈뇨를 표본 제작하여 먼저 위상차현미경적 표본제작법을 통하여 적혈구를 감별하였고 방법을 달리하여 주사형 전자현미경으로 요침사를 관찰하여 형태학적 고찰을 통하여 이형적혈구를 보다 명확한 3차원구조를 관찰할 수 있었다. 침생검을 통해 얻은 조직학적 소견으로는 사구체의 기저막을 통과한 혈구들의 요로를 통하여 배출과정을 광학현미경 및 투과형 전자현미경으로 확인할 수 있었다. 본 연구에서 육안적 혈뇨의 색은 유출되는 적혈구의 양과 상관관계가 있으며 용혈된 정도가 심한 경우에 콜라색 혈뇨가 있음을 알 수 있었다. 이들 결과에서 본 연구자들은 사구체성 질환을 동반한 유극적혈구 및 환형 적혈구 등과 같은 변형된 적혈구를 주사형 전자현미경으로 명확한 관찰을 함으로 사구체성 질환으로 인한 혈뇨의 감별에 주사형 전자현미경이 가장 유용한 검사 방법이라고 생각된다. Examination of the morphology of red blood cells in the urine has been shown to be a promising adjunct in determining whether hematuria represents glomerular or nonglomerular bleeding. This is due to distortion of RBCs as they pass across the basement membrane of the glomerular capillaries. It is concluded that is method can greatly help the clinician in distinguishing between glomerular and non glomerular bleeding in patients with hematuria and channeling such patients toward the most appropriate investigations. We have experimented dysmorphic red blood cells that 5 patients of the hematuria are distorted with irregular outlines and often have small blebs extruding from the red cell membrane. Tried urinary sediments were seen with phase contrast microscope and confirmed scanning electron microscope. There are seen acanthocytes, anulocytes, ghost cells and sphero-echinocytes in dysmorphic erythrocytes. Clinical diagnosis was referred from the result of the biopsy-proven. Scanning electron microscopic findings of the hematuria are good diagnostic tool that disclose in distorted red blood cells from patients with glomerular disorders.

HBA 양성환자의 혈청 Type Ⅳ Collagen 측정치 비교

윤기은,문희주,박정오 서울保健大學 1996 論文集 Vol.16 No.1

The purpose of this study was to analyze the concentration of serum type w Ⅳcollagen in HBV-DNA positive patients. The results were as follows. 1. As HBV-DNA concentration of serum grew higher, that of serum type Ⅳcollagen became lower gradually. 2. Total LDH activity had a significant relationship with concentration of serum type Ⅳcollagen up to l,000ng/mL. As HBV-DNA concentration of serum grew higher, total LDH activity became lower gradually. 3. Correlation serum type N collagen with AST(GOT) and ALT(GPT) appeared to have little relation compared to LDH. But each generally had the same change in direction. As HBV-DNA concentration of serum grew higher, those of AST and ALT were decreased drastically. These were no differences between the test group and a normal group.

세기말에 나타난 역사주의(Historicism)의상에 관한 연구

朴潤貞,楊淑喜 服飾文化學會 2000 服飾文化硏究 Vol.8 No.1

The purpose of stydy is explaining the Historicism as a result of compromise, historical eclecticism, between historical things and current cultural background instead of regarding it as an imitation from the past. It means that external factors in history help internal esthetic value surface out as costume. Fashions history is more than the classified thing according to the appearance with the changes of the times. Intrinsic cultural elements should be added in creating new fachion. One of the different features between Modernism and Post-modernism. When coming to the period of Post-modernism, it connected with the historical factors to make something new by fragmenating, magnifying, or minimizing them. This is calles "Historicism" in the world of art. It revived the past, not the past itself, in new ways: quotation, reuse, metaphor, and mixture. To represent the image, parody, pastiche, or bricolage was usually used. In post-modernism fashion, parody is a technique for imitating the past or the preceding forms with artists' own critical points of view. This technique gives us shock or surprise by using satirical, ironical or paradoxical expressions. pastiche shares the same part with parody in imitating particular or unique style, and it can be renamed empty parody, because it doesn't have any hidden motivation or satitical impulse,bricolage is a mixture of quotations from other works. It contains fragments that deepen the image. Like the techniques uttered above, the revival of history through parody, pastiche or bricolage is historical eclecticism and it is included in Historicism.

HBsAg 양성혈청에서의 HBeAg 및 anti-HBe 양성율과 ALT와의 관계 고찰

문희주,윤기은,박정오,배형준,최범열 서울보건대학 1996 서울보건대학 부설 한국보건과학연구소 논문집 Vol.3 No.1

The authors investigated HBeAg and anti-HBe in 1,000 cases(male 941, female 59) of HBsAg positive among the 225,512 blood donors in Seoul Nambu Blood Center in 1994. HBeAg and anti-HBe was detected by the method Enzyme Immunoassy. The results obtained were as follows ; 1. HBeAg and anti-HBe positive rates were detected 498 cases(49.8%) and 445 cases(44.5%) respectively among 1,000 cases HBsAg positive blood donors. 2. In HBsAg positive carriers, HBeAg positive rates were not significantly different between anti-HBe positive rates, but in sex were significantly different between HBeAg positive rates and anti-HBe positive rates. 3. HBeAg positive 498 cases were analyzed with age and it was found percentages of positive rates were 63.6% in 1st decade, 53.7% in 2nd decade, 20.6% in 3rd decade, 19.6% in 4th decade and 8.3% in over 5th decade, but anti-HBe positive 447 cases were 32.4% in 1st decade, 40.5% in 2nd decade, 69.2% in 3rd decade, 78.3% in 4th decade and 91. 7% in above 5th decade. 4. HBeAg positive rate decreased stepwise with age, while anti-HBe positive rate increased stepwise with age. 5. ALT abnormal cases in the HBeAg positive donors were higher than normal cases, but ALT normal cases in the anit-HBe positive donors were higher than abnormal cases.

人的資源會計의 測定과 모델

李喜均,南重憲,金潤泰 울산대학교 1986 연구논문집 Vol.17 No.1

人的資源의 原價 그리고 價値에 대한 測定은 人力計劃과 活用에 必須的이기 때문에 人的資源의 測定은 중요한 과제로 대두되었다. 人的資源會計의 모델은 經營者에게 人的資源活用에 대한 파라다임을 제공함으로써 人的資源을 效果的 혹은 效率的으로 이용하는데 도움을 줄 수 있다. 현재 人的資源會計가 널리 이용되지 않고 앞으로도 채택될 전망이 소극적이라면 그것은 다른 問題보다도 우선 測定上의 어려움이 존재하기 때문이다. 또한 人的資源의 測定方法은 여러가지가 있으나 보편적인 妥當性이 결여되어 있다. 따라서 本論文에서는 人的資源會計의 測定과 모델을 주안점으로 하여 여러가지 測定方法들과 모델을 평가하고 동시에 앞으로의 과제등을 살펴 보았다. For about recent ten years, The subject of human resource accounting has drawn great attention to many practices and studies because of the necessity of manpower planning and management, and it has been recognized that such a model will provide managers with a very good paradigm for making manpower more effectively and efficiently. But it is not long time untill we found some unnoticeable limitations and difficulties in estimation methods and applicative validity. Therefore, in this paper, It has been compared between many estimation models and suggested some issues for further studies from viewpoint of estimation models of human resource accounting.

尿中 Aminolevulinic Acid와 Porphobilinogen의 비교 조사 연구

나동진,윤기은,김승곤,문희주,김태전,박정오 서울保健大學 1990 論文集 Vol.10 No.1

This studies were examined to measure total ALA and PBG concentration in Urine, and find the relationship of correlation among them in 57 men unexposed and 43 men exposed by mercury. The results were summarized as the following; 1. In 100 populations total urine ALA concentration was 0.85±0.17㎎% in male, in female were 0.40 ± 0.04㎎% (normal value : 0.54㎎%). 2. Urine ALA concentration in male were 1.04∼1.11mg% for the ages between 30 ∼ 49 was the highest and then in female were 0.58㎎% for the ages between 40 - 59 was the highest. 3. In 100 populations total urine PBG concentration was 0.03㎎% in male, in female were 0.02㎎% (normal value : 0.03㎎%). 4. Urine PBG concentration in male were 0.05㎎% for the ages between 30-49 was the highest. 5. In unexposed men group total urine ALA concentration was 0.13±0.03㎎% in male, in female were 0.11±0.0l㎎%. 6. In exposed men group total urine ALA concentration was 1.81±0.55㎎% in male, ill female were 0.78±0.09㎎%, there was differences in attention showing male was higher than the female (P<0.05). 7. In unexposed men group total urine PBG concentration was 0.02㎎% in male, in female were 0.0l㎎%. 8. In exposed men group total urine PBG concentration was 0.06㎎% in male, in female were 0.04㎎%,there was differences in attention showing male was higher than the female (P<0.05).

供血者에서의 HBsAg 發現率과 生化學的 檢査値에 관한 硏究

문희주,윤기은,김승곤,라동진,김태전,박정오,최범열 서울保健大學 1988 論文集 Vol.8 No.1

병원내 생리기능 검사실의 적정 업무환경에 관한 연구

배형준,윤기은,김승곤,나동진,문희주,김태전,박정오 서울보건대학 1999 서울보건대학 부설 병원경영연구소 논문집 Vol.4 No.2

The purpose of this study was to suggest guideline for optimal work environment of physiological laboratory in hospital. Therefore this study was carried out to analyze the actual condition of laboratory system, major equipments and persons. The period of survey was from September to November 1997 and the objects were 123 laboratory. The major results of this study were as follows. 1. The optimal areas of general ECG room, exercise ECG room and echocardiology room were all 9-18㎡, that of Holter ECG room was 3-12㎡. The optimal areas of neurosystem laboratory were all 9-12㎡, those of respiratory system laboratory were all 9-18㎡. 2. The optimal number of persons laboratory of hospital 500 beds and less were 2∼3, those of 501∼700 beds were 3∼4.701∼1.000 beds were 4∼5 and over 1.001 beds were 7∼8 persons in circulatory system laboratory. The optimal number of persons laboratory of hospital 500 beds less than were 1∼2, those of 501∼700 beds were 3∼4, 701∼1.000 beds were 6∼7 and over 1.001 beds were over 8 persons in neurosystem laboratory. The optimal number of persons laboratory of hospital 500 beds and less 1. those 501∼1.000 beds were 1∼2 and over 1.001 beds were 2∼3 persons in repiratory system laboratory. 3. The optimal number of equipments of general ECG were 2∼3 in the 500∼1.000 beds hospital. there were 3∼4 units in the 1,001 beds. The optimal number of equipment EEG were both 1∼2 in the hospital 500 beds and less and 501∼700 beds. those were 4∼5 units in hospital over 701 beds. The optimal number of equipments of spirograph were both 1∼2 in the hospital 500 and less and 501∼1.000 beds. those were 2∼3 units in the over 1.001 beds. 4. In view of speciality and legal problem of physiofunctional test. we sugget that non-licensee were so quickly change place licensee in the interests of optimal work environment. 5. We suggest that to upgrade qualitative level of domestic equipment and to the more amplify utilization with respect to domestic equipment for the purpose of reducing loss of foreign money.

한국어교육 전공 발전 방안에 대한 연구

閔賢植,尹希苑,金鍾澈 서울대학교 국어교육과 2002 先淸語文 Vol.30 No.-

In the last 10 years Korean language education has made a wonderful growth in the method of study and teaching. Korean language is competitive enough in the international language market though the competitive power of Korean language is insufficient than Japanese and Chinese language. We should resolve many problems of Korean language education. For example, we should develop various curriculum, materials, technique of teaching and evaluating tools according to the need of learners and teachers. First of all we should train and produce excellent teachers who can teach Korean language as a foregin language or second language. Now the teachers of this field are trained in the irregular short-term programs founded in some major universities for commercial enterprise. Recently some academic degree courses have been founded in major universities also. But the management of all these degree courses and programs have many problems in curriculum, practice of teaching, professors of majors, official certification, appointment, and reeducation. Especially now the status of these trained teachers in this field can not be guaranteed by the national laws and Administration of Education. Therefore we should readjust the curriculum of regular degree courses and irregular short-term programs, and certificate the students by the official certification system. The curriculum of regular degree course should set these subjects as a standard curriculum: linguistics, Korean linguistics, language education, Korean language education as a foreign language or second language, Korean culture, Korean literature, method of language teaching, language acquisition, contrastive analysis of language, analysis of errors, practice of teaching for 1-6 months, and theory of language teaching.

金綱 充塡管을 통한 氣體-固體의 輸送에 관한 硏究

咸榮敏,趙熙俊,洪英浩,張潤鎬 단국대학교 1987 論文集 Vol.21 No.-

This study was carried out to investigate the effect of solid mass flow rate and mean particle diameter on minimun carrying velocity, which was defined as the superficial gas velocity of the upper limit of choking phenomenon, when vertical pneumatic conveying was made through a screen-packed pipe whose inner diameter and length were 4.6cm and 180cm respectively. It was also examined the effect of superficial gas velocity, solid mass flow rate and mean particle diameter on pressure drop. And these minimum carrying velocity and pressure drop were compared with those in an empty pipe. Superficial gas velocity was taken 3.0m/sed to 5.5m/sec. Solid mass flow rate was controlled by five orifices which had different opening dimensions and its range was 2.90g/sec to 16.35g/sec. Silica sand of three sizes (mean diameter; 425㎛, 280㎛, 180㎛) was used as solid particle. The pressure drop in a screen-packed pipe increased as superficial gas velocity, solid mass flow rate and mean particle diameter increased. And the pressure drop in an empty pipe also increased according to the increase of solid mass flow rate, but it decreased though superficial gas velocity increased within the range of experimental conditions. In the case of minimum carrying velocity, it increased as solid mass flow rate and mean particle diameter increased. The pressure drop in a screen-packed pipe was far higher than that in an empty pipe. However, the minimum carrying velocity in the former was slightly lower than that in the latter.