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Park, Chang-hyun,Chang, Won Hyuk,Yoo, Woo-Kyoung,Shin, Yong-Il,Kim, Sung Tae,Kim, Yun-Hee Mary Ann Liebert 2014 Brain connectivity Vol.4 No.4
<P>Repetitive transcranial magnetic stimulation (rTMS) influences the brain temporally beyond the stimulation period and spatially beyond the stimulation site. Application of rTMS over the primary motor cortex (M1) has been shown to lead to plastic changes in interregional connectivity over the motor system as well as alterations in motor performance. With a sequential combination of rTMS over the M1 and functional magnetic resonance imaging (fMRI), we sought changes in the topology of brain networks and specifically the association of brain topological changes with motor performance changes. In a sham-controlled parallel group experimental design, real or sham rTMS was administered to each of the 15 healthy subjects without prior motor-related dysfunctions, over the right M1 at a high frequency of 10 Hz. Before and after the intervention, fMRI data were acquired during a sequential finger motor task using the left, nondominant hand. Changes in the topology of brain networks were assessed in terms of global and local efficiency, which measures the efficiency in transporting information at global and local scales, respectively, provided by graph-theoretical analysis. Greater motor performance changes toward improvements after real rTMS were shown in individuals who exhibited more increases in global efficiency and more decreases in local efficiency. The enhancement of motor performance after rTMS is supposed to be associated with brain topological changes, such that global information exchange is facilitated, while local information exchange is restricted.</P>
해도분석을 통한 낙동강 하구 사주 면적의 시ㆍ공간 변화
유창일(CHANG-ILL YOO),윤한삼(HAN-SAM YOON),류청로(CHEONG-RO RYU),이인철(IN-CHEOL LEE) 한국해양공학회 2006 韓國海洋工學會誌 Vol.20 No.6
This study discusses characteristic of spatiotemporal changes of the sand barrier in the Nakdong estuarine for the last century, focusing on geomorphologic evolution and mobility of sand barriers in the view of coastal engineering. The Nakdong estuarine, the research subject, has a complexly changing natural environment by interaction between ground and marine elements such as ocean wave, tidal current, sediment, etc. Moreover, recently, unnatural geomorphologic changes (e.g., seaside reclamation, new harbor construction, etc.) has been radically increased in this area with increasing desire for coastal development. Because of this, its sand barrier has developed quite unstable condition. Therefore, to identify the development process of geomorphologic changes in this area, required is a close examination on historical characteristics of spatiotemporal changes of the sand barrier in relation to surrounding seaside reclamation and physical environmental changes. This study, based on the marine charts published in between 1927 and 1995 year, analyzes the length and area of the sand barrier for the last hundred years, and investigates the cause of the changes by looking into the change of water depth for the last two years and doing ocean-physical site observations. In conclusion, the sand barrier of the Nakdong estuarine expands toward the open sea by 7.4~26 m in annual average, maintaining a fixed distance of 1,241~1.279 m, and its area is expected to increase about 2.8 k㎡ annually. This is characterized by the wocean wave from the open sea and the discharge of Nakdong River.
( Byung Ju Kang ),( Kyung Wook Jo ),( Tai Sun Park ),( Jung Wan Yoo ),( Sei Won Lee ),( Chang Min Choi ),( Yeon Mok Oh ),( Sang Do Lee ),( Woo Sung Kim ),( Dong Soon Kim ),( Tae Sun Shim ) 대한결핵 및 호흡기학회 2013 Tuberculosis and Respiratory Diseases Vol.75 No.6
Background: The aim of our study was to evaluate the “diagnosis changed” rate in patients notified as tuberculosis (TB) on the Korean TB surveillance system (KTBS). Methods: A total of 1,273 patients notified as TB cases on the KTBS in one private tertiary hospital in 2011 were enrolled in the present study. Patients were classified into three groups: “diagnosis maintained”, “diagnosis changed” (initially notified as TB, but ultimately diagnosed as non-TB), and “administrative error” (notified as TB due to administrative errors). Results: Excluding 17 patients in the “administrative error” group, the “diagnosis maintained” and “diagnosis changed” groups included 1,097 (87.3%) and 159 patients (12.7%), respectively. Common causes of “diagnosis changed” were nontuberculous mycobacterial (NTM) disease (51.7%, 61/118), and pneumonia (17.8%) in cases notified as pulmonary TB, and meningitis (19.5%, 8/41) and Crohn`s disease (12.2%) in cases notified as extrapulmonary TB. Being older than 35 years of age (odds ratio [OR], 2.18) and a positive acid-fast bacilli stain (OR, 1.58) were positive predictors and a TB-related radiological finding (OR, 0.42) was a negative predictor for a “diagnosis changed” result via multivariate logistic regression analysis in pulmonary TB cases. Conclusion: Because of a high “diagnosis changed” rate in TB notifications to the KTBS, the TB incidence rate measured by the KTBS may be overestimated. Considering the worldwide trend toward increased NTM disease, the “diagnosis changed” rate may increase over time. Thus, when reporting the annual TB notification rate in Korea, the exclusion of “diagnosis changed” cases is desirable.
성창훈 ( Chang Hoon Seong ),유루경 ( Lu Kyung Yoo ),장채욱 ( Chae Ouk Jang ) 한국스포츠심리학회 2008 한국스포츠심리학회지 Vol.19 No.2
이 연구는 노인의 운동실천 제약요인을 탐색하고 범이론적 모형(TTM)에 기초하여 운동행동변화단계에 따른 제약요인의 차이를 알아보고자 하였다. 이를 위해 운동을 실천하고 있거나 실천하지 않는 60제 이 상 103명의 노인을 대상으로 개방형 설문을 실시하였으며, 이 결과를 토대로 개발된 운동실천 제약요인 척도를 활용하여 309명의 자료를 수집하고 제약요인의 구조 및 운동행동변화단계에 따른 차이를 검증하였다. 연구결과, 노인들의 운동실천을 제약하는 6개요인(부상우려, 운동지식 부족, 건강상실과 질병, 운동동기 부족, 시간기회 부족, 경제여건)이 발견되었으며, 운동행동변화단계에 따른 제약요인의 차이를 분석한 결과에서는 성과 연령 및 운동행동변화단계에 따른 상호작용효과 및 주 효과가 동시에 나타나 복잡한 양상을 보여주었다. 성과 연령을 함께 고려할 때, 운동행동변화단계를 가장 잘 판별하는 제약요인은 건강상실과 질병요인이었다. 이러한 결과는 노인의 운동실천 제약요인의 타당성과 중재전략 개발 의 방향성 및 후속연구의 과제와 관련하여 논의하였다. This study, based on hierarchial model of leisure constraints and trans-theoretical model(TTM), aimed to investigate the conceptual structure of exercise constraints in the aged and the difference according to the stages of change of exercise. The data were collected via a open-ended questionnaire(103 age of over 60) and self-administrated residents questionnaire survey(309 aged people) in incheon city in Korea. content analysis, descriptive and inferential analyses including factor analysis, three-way MANOVA through the stepdown F-test were used to analyze the data. The results of the study showed that the constraint dimension of exercise in the aged were 6 multi-dimensional factors, which were lack of knowledge and information to exercise, bed health and illness, motivation loss, lack of time and chance, low economic condition. Furthermore, as the results of analysis on the differences according to the stages of change of exercise, 6 constraints of exercise offered a significant contribution towards the prediction of the stages of change. The bed health and illness dimension was the best predictor for distinguishing among the stages of change considered the gender x age x stages of change effects. These results were discussed relate to cross validity of constraints and strategy of intervention for regular exercise participation.
Jin-A Oh,Jong-Chun Cheong,Chan-Jung Lee,Chang-Sung Jhune,Young-Bok Yoo 한국버섯학회 2010 한국버섯학회지 Vol.8 No.4
The standard does much to improve merchantable quality, distribution efficiency and fair dealings by shipping of the standard agricultural products. Mushrooms notified as the standard are five items; Pleurotus ostreatus, Pleurotus eryngii, Flammulina velutipes, Agaricus bisporus and Ganoderma lucidum. But many farmers are suffering from a strict standards. So these standard is required modification to fit farmhouse situations. This study was carried out to investigate mushroom quality of farm shipping and quality change during preservation at various treatment. Flammulina velutipes and Agaricus bisporus preserved at different temperature( 4℃, 10℃, 20℃) to investigate quality changes. Pileus diameters of Flammulina velutipes was 67% of first grade and 33% of second grade at the early stage. After two weeks, pileus diameters was not signigicant changes; 50% of first grade, 50% of second grade at 4℃ and 50% of second grade, 50% of third grade at 10℃. Although there were no significant changes of diameter at 20℃, most of the fruit bodies were decayed. In case of Agaricus bisporus, pileus diameter was 15% of first grade, 81% of second grade and 4% of third grade at the early stage. The more storage period longed, the more the color of the fruit body was browned. But pileus diameters was not signigicant changes. Hardness and chromaticity of these mushroom was declined as time passed. Now we are carrying out more research on some mushroom’s standards for improve consumer confidence.
HWANG, IN,LEE, HYEON,YOO, KI-YEON,KIM, DAE,KIM, JUNG,KIM, CHANG,LIM, BEONG,KANG, TAE-CHEON,BANG, KYUNG,SEONG, NAK,LEE, HAK,KIM, JONG,WON, MOO Taylor Francis 2006 International journal of neuroscience Vol.116 No.8
<P>The present study examined ischemia-related changes in tyrosine kinase A (trkA) immunoreactivity and its protein content in the dentate gyrus after 5 min of transient forebrain ischemia in gerbils. One day after ischemic insult, cresyl violet-positive polymorphic cells showed ischemic degeneration. The ischemia-induced changes in trkA immunoreactivity were found in the polymorphic layer (PL) and granule cell layer (GCL) of the dentate gyrus. In the sham-operated group, trkA immunoreactivity in the dentate gyrus was very weak. From 30 min after ischemia, trkA immunoreactivity was increased in the dentate gyrus and peaked in the dentate gyrus at 12 h after ischemia-reperfusion. Thereafter, trkA immunoreactivity was decreased time-dependently after ischemia-reperfusion. Four days after ischemic insult, trkA immunoreactivity was similar to that of the sham-operated group. In addition, it was found that ischemia-related changes in trkA protein content were similar to the immunohistochemical changes. These results suggest that the chronological changes of trkA in the dentate gyrus after transient forebrain ischemia may be associated with ischemic damage in polymorphic cells of the dentate gyrus.</P>
Kang, Byung Ju,Jo, Kyung-Wook,Park, Tai Sun,Yoo, Jung-Wan,Lee, Sei Won,Choi, Chang-Min,Oh, Yeon-Mok,Lee, Sang-Do,Kim, Woo Sung,Kim, Dong Soon,Shim, Tae Sun The Korean Academy of Tuberculosis and Respiratory 2013 Tuberculosis and Respiratory Diseases Vol.75 No.6
Background: The aim of our study was to evaluate the "diagnosis changed" rate in patients notified as tuberculosis (TB) on the Korean TB surveillance system (KTBS). Methods: A total of 1,273 patients notified as TB cases on the KTBS in one private tertiary hospital in 2011 were enrolled in the present study. Patients were classified into three groups: "diagnosis maintained", "diagnosis changed" (initially notified as TB, but ultimately diagnosed as non-TB), and "administrative error" (notified as TB due to administrative errors). Results: Excluding 17 patients in the "administrative error" group, the "diagnosis maintained" and "diagnosis changed" groups included 1,097 (87.3%) and 159 patients (12.7%), respectively. Common causes of "diagnosis changed" were nontuberculous mycobacterial (NTM) disease (51.7%, 61/118), and pneumonia (17.8%) in cases notified as pulmonary TB, and meningitis (19.5%, 8/41) and Crohn's disease (12.2%) in cases notified as extrapulmonary TB. Being older than 35 years of age (odds ratio [OR], 2.18) and a positive acid-fast bacilli stain (OR, 1.58) were positive predictors and a TB-related radiological finding (OR, 0.42) was a negative predictor for a "diagnosis changed" result via multivariate logistic regression analysis in pulmonary TB cases. Conclusion: Because of a high "diagnosis changed" rate in TB notifications to the KTBS, the TB incidence rate measured by the KTBS may be overestimated. Considering the worldwide trend toward increased NTM disease, the "diagnosis changed" rate may increase over time. Thus, when reporting the annual TB notification rate in Korea, the exclusion of "diagnosis changed" cases is desirable.
김태환 ( Tae Hwan Kim ),전재범 ( Jae Bum Jun ),심승철 ( Seung Cheol Shim ),장대국 ( Dae Kook Chang ),고회관 ( Hee Kwan Koh ),정성수 ( Sung Soo Jung ),이인홍 ( In Hong Lee ),배상철 ( Sang Cheol Bae ),유대현 ( Dae Hyun Yoo ),전의용 대한류마티스학회 1998 대한류마티스학회지 Vol.5 No.2
목적: 천장골염의 유무가 척추 관절염의 진단에 중요한데 단순 골반 검사에서 변화가 없는 환자를 대상으로 MRI를 이용하여 천장골염의 조기변화 소견 및 MRI방법에 따른 장점을 비교하고자 하였다. 대상 및 방법: 단순 골반 검사에서 천장골염 유무가 확실하게 구분되지 않은 혈청 음성 척추 관절염 환자 26명을 대상으로 MRI를 시행하고 염증의 주침범위치를 천측과 장측, 관절의 상하로 구분하고, MRI방법에 따른 변화를 비교하였다. 결과: 모든 예에서 조영 증강되는 판누스를 관찰할 수 있었고, Grade I 이하에서는 장골측과 관절하부, 인대성 관절보다 활막성 관절을 더 많이 침범하였다. Grade II 이상에서도 장골측과 관절 하부에 더 많았으나 인대성 관절을 Grade I이하에서보다 더 많이 침범하였다. 관절 주변 지방 침착역시 장골측과 관절 하부에 더 주로 침범하였고 Grade II 이상에서 약간 더 많았다. 관절 주변 골염은 Grade 0에서는 없었고, Grade I에서는 주로 장골측과 관절 하부에서 92%가 양성이었고, Grade II에서는 93%에서, Grade III에서는 64%에서 양성으로, 장골측을 주로 침범하였으나 관절 상하부의 구분은 없었다. 인대성 천장골 관절은 Grade I 이하에서 38%, II 이상에서는 94%에서 침범하였다. 관절 주변 골염과 지방 침착, 그리고 판누스의 관찰에는 MPGR보다 스핀에코 영상이 좋았고, 관절면의 불규칙성 또는 관절강의 확대와 관절 강직여부의 관찰에는 스핀에코에 비해 MPGR 영상이 좋았고, 연골하 경화는 비슷하였다. 천장골염의 정도와 ESR, CRP와의 연관성은 없었다. 걸론: 천장골 관절에서 염증의 시작은 주로 장골 측과 관절의 하부에서 먼저 시작되고, 관절이 진행될수록 장골측에서 천골측까지로 범위가 확대 되었다. MRI방법에 의한 차이로 초기단계에는 스핀에코 영상이 관절염을 확인하는데 도움이 되고 관절면이 불규칙하게 되고 경화가 되어 병이 진행된 상태에서는 MPGR영상이 진단에 더 도움이 되었다. 염증성 배부 동통이 있는 경우 단순 골반 검사에서 이상이 없는 환자인 경우에도 MRI 검사를 시행하여 천장골염의 유무를 확인하는 것이 중요하다. Objective: The early detection of sacroiliitis on X-ray is important to diagnose spondyloarthropathy(SpA). The conventional radiography, bone scan, and computer tomogram have the problems of sensitivity, specificity, and side effects. We examined sacroiliitis using MR imaging in patients who had inflammatory back pain, but no definite changes in conventional radiogrphy. Other radiologic techniques were compared in detection of early sacroillitis. Methods: Twenty six patients with SpA were examined. The MRI findings of both sacroiliac joints were evaluated in every patients, such as pannus, periarticular osteitis and fat accumulation, subchondral sclerosis, and joint space changes(irregularity, ankylosis). Also we analyzed the changes of sacroiliac joints in sacroiliitis. Results: The predominant sites of involvement were upper aspect and iliac surface of sacroiliac joint in subchondral sclerosis, lower and iliac in pannus, periarticular fat accumulation, and iliac in periarticular osteitis. The MPGR images were superior to spin echo images in evaluation of joint space changes(irregularity, and ankylosis). Conclusions: Sacroiliitis is initiated in iliac side and lower portion of sacroiliac joints. MRI can detect early changes of sacroiliitis in patients with no conventional radiographic changes. MRI seems to be needed in patients with inflammatory back pain.
운동강도와 생리주기의 변화가 혈액성분농도에 미치는 영향에 관한 연구
유창재 新羅大學校 1992 論文集 Vol.34 No.1
This paper was attempted to clarify the change pattern of concentration in blood components by the change in menstrual phase, and the response during gradual exercise load. The subjects selected for the experiment were six trained female students and six untrained female. All the subjeets had regular menstrual phase and all were in good health. They performed the maximal exercise on treadmill. Blood collecting was made at the static state, at the time of 40%VO₂max, and all-out time in each menstrual phase. The results are as follows. 1) The level of T-protein concnetration between two groups in three menstrual phase did not appear significantly. At exercise intensities, the level of all-out time was highest and in the 40%VO₂max the level was lowest. 2) Athletic growp's Albumin concentration was slightly higher than nonathletic group's. The level of follicular phase was highe than any other menstrual phase. There was no significant difference among three exercise intersities. 3) The level of Cholesterol concentration was no significant in two groups, in three menstrual phases and three exercise intensities. 4) RBC count was slightly greater in the athletie group than in the nonathletic group. But there were no Significant difference among three menstrual phase and among exercise intensities respectively. 5) WBC count was Slightly greater in the monathletie group than in the athletic group at rest and level exercise phase throughout all menstrual phase. Among exercise intersities. WBC count was greatest in all-out time. 6) Hb concentration was slightly higher in athletic group than in nonathletic group at static state and it was alike in all exercise intensities throughout all menstrual phase. The value was slightly high in the all-out time among three exercise intensities. No significant difference was shown among three menstrual phases. 7) The level of Hct concentration was higher in the athletic group than in the nonathletic group at static state and exercise. Thicker density was seen at all-out time among three exercise intensities.