두경부 편평세포암에서 형질전환 성장인자-알파(TGF-α)의 발현에 관한 연구

도남용,이승학,김완수,김경일,이동용,김용기,최봉남 조선의대 1996 The Medical Journal of Chosun University Vol.21 No.2

아치 리브를 따라 작용하는 등분포 하중을 받는 포물선 아치 리브의 비탄성 면내좌굴 강도

윤기용,문지호,김성훈,이학은,Yoon. Ki-Yong,Moon. Ji-Ho,Kim. Sung-Hoon,Lee. Hak-Eun 한국방재학회 2005 한국방재학회논문집 Vol.5 No.1

포물선 아치 리브는 원형 아치 리브와 더불어 실무에 폭넓게 적용되고 있는 아치 형상이다. 원형 아치 리브의 비탄성 면내 거동에 관한 연구는 1990년대 Trahair(1996)를 중심으로 연구가 진행되었으며, Yong-Lin Pi와 Bradford(2004)에 의하여 최근까지 연구가 활발히 진행 되고 있다. 포물선 아치 리브의 비탄성 면내 거동에 관한 연구는 일본의 연구자(Sinke, Kuranishi)을 중심으로 1970년대 후반부터 1980년대 초반에 이르기까지 많은 연구가 진행되었다. 이러한 포물선 아치 리브에 관한 일본에서의 연구는 대부분 라이즈비가 <TEX>$0.1{\sim}0.2$</TEX>에 국한 되어있다. 본 연구에서는 비탄성 유한요소해석을 이용하여 라이즈비가 0.1에서 0.4에 이르는 박스형태의 단면을 갖는 포물선 아치 리브의 면내 거동에 관하여 연구를 수행하였다. 연구 결과 라이즈비가 증가할수록 아치 단면에 휨모멘트가 증가하였으며, 압축력이 수직 등분포 하중을 받는 포물선 아치 리브의 면내 좌굴 안정성에 미치는 영향은 감소하였다. 마지막으로 본 연구에서는 아치 리브를 따라 작용하는 수직등분포 하중을 받는 포물선 아치의 좌굴 곡선을 제안하였다. Parabolic arch ribs are widely used in practical. In case of circular arch ribs. Inelastic in-plane buckling behaviors were investigated by Trahair(1996). Recently Yong-lin Pi & Bradford(2004) investigated about in-plane design equation for circular arch ribs. In <TEX>$1970{\sim}1980$</TEX>. In-plane buckling strength about parabolic arch ribs were studied by some japan researchers (Sinke, Kuranishi). Study results of Sinke & kuranishi are only valid for rise-span ratio <TEX>$0.1{\sim}0.2$</TEX>. In this paper. The researchers investigated about in-plane inelastic buckling behaviors of parabolic arch ribs having rise-span ratio from 0.1 to 0.4. From the results. When the rise-span ratio increase, flexural moments increase and influence of axial force to in-plane buckling strength decrease. Finally, buckling curves for parabolic arch ribs subjected distributed loading along the axis were suggested.

급성하벽심근경색에서 전흉부유도 ST절 하강의 의의

정병천,배호상,곽동훈,김영태,배용학,황종현,임현주,류재근,조용근,채성철,전재은,박의현 慶北大學校 醫科大學 1997 慶北醫大誌 Vol.38 No.2

목적 : 급성하벽심근경색증 환자에서 심전도상 흔히 동반되는 전흉부유도 ST절 하강의 의의를 알아보았다. 방법 : 심근경색후 24시간에서 48시간에 얻은 심전도를 기준으로 52명의 급성하벽심근경색증 환자를 전흉부유도에서 ST절의 하강이 있는 군과 없는 군으로 나누었으며 심도자, 관상동맥조영술, 심초음파도 및 방사성 핵종을 이용한 좌심구혈율 측정 등을 시행하였다. 결과 : 1) 좌심실확장기말압은 전흉부유도에서 ST절의 하강이 있는 경우에서 16.9±5.33mmHg로 없는 경우의 11.0±4.02mmHg보다 유의하게 높았다(p<0.05). 그러나 운동량 및 좌심구혈을은 흥부 유도상 ST절의 하강이 있는 경우 7.6±3.0 METs 및 53.9±9.1%로 없는 경우의 9.1±2.7 METs 및 54.6±9.5%보다 낮았으나 통계적 유의성은 없었다(p=0.180, p=0.823). 2) 관상동맥조영술상 전흉부 ST절의 하강이 동반된 군에서는 유의한 좌전하행지나 좌회선지의 협착이 있는 경우가 60.9% 및 57.9%로 ST절의 하강이 없는 군에서의 34.5% 및 7.7%와 비교해 좌관상동맥에 협착이 동반된 경우가 많았다(p=0.050, p=0.001). 3) 관상동맥조영술상 세 혈관질환의 빈도는 흉부유도상 ST절의 하강을 보인 23예에서 10예로 ST절 하강이 없었던 29예중 2예에 비하여 유의하게 많았고(P=0.007), 단 혈관질환의 빈도는 ST절의 하강을 보인 군에서 23예중 5예로 ST절 하강이 없었던 29예중 17예에 비하여 유의하게 적었다(P=0.002). 두 혈관질환의 경우에는 각각 8예와 10예로 양군간에 유의한 차이가 없었다. 4) 흉부유도상 ST절 하강의 빈도는 단 혈관질환 22예 중 5예에서, 두 혈관질환 18예중 8예, 세 혈관질환 12예 중 10예에서 관찰되어 협착이 있는 관상동맥의 수가 많을수록 ST절의 하강이 나타나는 빈도가 많음을 보였다(p=0.00308). 그러나 흉부유도상 나타난 ST절의 하강을 모두 합하여 구한 ST절 하강의 합은 협착이 있는 관상동맥의 수와 통계적인 유의성이 없었다. 5) 심초음파도상 좌심실 하벽의 벽운동은 ST절 하강을 보인 군에서는 akinesia가 83.3%, hypokinesia가 11.1%, 정상 벽운동이 5.6%로, ST절 하강이 없었던 군에서의 dyskinesia가 3.6%, akinesia가 39.3%, hypokinesia가 25.0%, 정상 벽운동이 32.1%와 비교하여 ST절의 하강이 있는 군에서 유의하게 벽운동의 장애가 빈번함을 보였다(p=0.03891). 그러나 좌심실전벽, 측벽 및 중격부위에서는 유의한 벽운동의 차이가 없었다. 결론 : 급성하벽심근경색증 환자의 전흉부유도에서 ST절의 하강이 동반되는 경우 다혈관 질환의 가능성이 높으며 좌심실확장기말압이 상승되었고 운동능력은 감소되어 있었다. 또한 심초음파도상 좌심실하벽의 벽운동장애도 심하였다. 따라서 전흉부 ST절의 하강을 동반한 급성하벽심근경색증 환자는 전흉부유도에 ST절 하강이 없는 경우보다 예후가 불량할 것으로 생각되며, 보다 적극적인 치료가 필요할 것으로 생각된다. The purpose of this study was to determine the significance of precordial ST segment depression appearing during acute inferior myocardial infarction and to assess the correlation of that with angiographic finding. 52 patients were allocated into two groups based on the existence of precordial ST segment depression : 23 patients with ST segment depression and 29 patients without ST segment depression. The extent of coronary artery disease as well as the prevalence of significant stenosis (≥70%) in left anterior descending artery were more frequent in patients showing precordial ST segment depression than in patients not showing them (p=0.050) and the result were similar in cases of left circumplex artery (p=0.001). On echocrdiographic examination of left ventricular (LV) wall motion, it showed more severely decreased inferior LV wall motion in patients showing precordial ST segment depression than in patients not showing them (p=0.03891) even though the other segment of LV wall motion didn't show the statistical difference between both groups. The other cardiac parameters such as LVEDP, exercise amount (METs) and ejection fraction were tend to showing bad profile in patients with precordial ST segment depression. From the above results, we could deduce that patients with precordial ST segment depression have relatively large infarction or concomitant left coronary artery disease, so they need more caution and intensive theraphy.

위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구

노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.

비구조적 퍼지 의사결정지원시스템을 활용한 건설재해 예방대책에 관한 연구

이용준,정성춘,이학기 東亞大學校 建設技術硏究所 2004 硏究論文集 Vol.27 No.2

The hazard factors in building construction project are various and their bad effects with regard to project's efficiency are increasing due to its enlargement and complexity. However. the assessment of the construction safety is commonly dependent upon the statistical and historical information. since the existing systematic tool assisting to the effective decision making for estimating the safety prior to construction phase is inaccurate. In addition. it is true that there are the various difficulties to analyze and diagnosis the construction safety with the probabilistic approach. because there are the many vague factors and limited resources. Therefore. the purpose of this research is to provide the way to establish the efficient preventable countermeasure against the hazard factors. corresponding to the category of the hazard characteristic. by using non-structural fuzzy decision support system for diagnosing effectively the construction project safety.

本國劍法의 意味와 方法에 關한 硏究

김영학,허건식 龍仁大學校 1998 용인대학교 논문집 Vol.15 No.-

Bonkukkumbub is quire different from Japan Kumdo based on the review of the meanings and methods. The differences were shown by the various front-rear and right-left movement in the Bonkukkumbub patterns compared to Japan Kumdo patterns. Also. Bonkukkumbub was differenct from sport Kumdo which was modernized for the sport game. This Bonkukkumbub was originated in Shilla dynasty which was found in the literature to be used for the training of Hwarang. Therefore, Bonkukkumbub has its meanings for the study of foundation for Koreanized Kumdo today. However, the similarity between Hwarang Kumsool and Bonkukkumbub was not identified in this study, and the further research will be required. The main similarity in the posture between Bonkukkumbub and Japan Kumdo were shown and its reasons why the similarity was shown could be based on the two stories. First, Bonkukkumbub was transferee to Japan and the similar patterns were still existed. Second, the similar postures could be essential in any kind of Kumdo patterns because of its advantage to compete Therefore, the posture in Kumdo should be studied in the future.

자발성 기흉을 동반한 폐림프관평활근종증 1예

안용환,정종훈,김소영,김휘정,김학렬,양세훈,최순호,문형배,조향정,정은택 圓光大學校 醫科學硏究所 2005 圓光醫科學 Vol.20 No.1

Cavity내의 난류유동에 따른 열전달 특성에 관한 硏究

朴炳學,李勇虎 麗水水産大學校 産業技術硏究所 1993 産業基術硏究所 論文集 Vol.2 No.-

When a flow passes cavity, vortex flow is formed by separation. At this time, the characteristics of heat transfer are very important in these flow fields. Almost all of the studies are restricted to the shallow cavity so far, but in this study, heat trasfer in rectanular cavity having depth-width ratios of 0.5, 1 and 1.5 is studied. In this experiment, a range of the measured Reynolds number is 5.1×10⁴~??. In subsonic flow through the wind tunnel, the following results are obtained from the data given by heating the cavity bottom in the given range of Reynolds number. 1) With increasing depth of cavity, the coefficient of mean heat transfer is decrease. In order to increase the coefficient of heat transfer in cavity, therefore, shallow cavity is used. 2) In case of cavity with constant D/W, coefficient of heat transfer increases with increasing Reynolds number. 3) When a cavity is in the flow field, there are maximum and minimum point of very coefficient of heat transfer due to vortex or separation phenomena. 4) With increasing depth of the cavity, a large vortex is remarkable in it, and the strength of vortex is noticeable in the second half of the cavity. 5) When a cavity is in flow field, the relationship between Nusselt number and Reynolds number is as follows: Nu? = 5.693 Re at depth-width ratio = 0.5 Nu? = 10.329 Re at depth-width ratio = 1 Nu? = 0.836 Re at depth-width ratio = 1.5

언향적 화행의 관점에서 본 영어 요청화행

백용학 東亞大學校 2001 東亞論叢 Vol.38 No.-

The illocutionary act can be redescribed as the perlocutionary act with the hearer's response because perlocutionary act is brought about through the illocutionary act. The request speech act belongs to the illocutionary act in terms of the speaker, while this act, perlocutionary act from the point of the hearer. The hearer's response called illocutionary perlocution can be differed by various linguistic situations. The purpose of this study is to test and analyze the hypothesis that the linguistic situations of the request speech act do not always make the hearer choose the same request expression. We can assume that the request speech act in the interest of the speaker and normally at the cost of the hearer can have different illocutionary request types. The analytic results of my study are as follows: In the linguistic situation of the speaker's requesting to borrow the hearer's pen, many hearers(55%) prefer hearer-based conventional indirect request types. In the linguistic situation of the speaker's requesting the hearer to clean the room, most of listeners(67%) like the hearer-based conventional indirect request types. There is also the preference difference of the request speech act between the male and female testees. In the linguistic situations of speaker's requesting the hearer to close the door, many of testees select nonconventional request types. On the other hand, in the linguistic situation of the speaker's requesting the hearer not to smoke, most of testees prefer direct request types to any other request types. In conclusion, the linguistic situation decides the request speech act types. In addition, male and female testees require different request speech act types each other. This analysis, however, can not absolutely apply to the any kind of social level, because the testees do not represent various strata of society.

감차(Hydrangea serrata Seringe var. Oamacha Honda)의 삽목번식에 關한 硏究

金鶴起,朴容珍 江陵大學校東海岸地域硏究所 1993 東海岸硏究 Vol.4 No.1

본 연구는 조경식물 및 차의 재료식물로서 개발이 유망한 감차의 무성번식방법을 구명하기 위하여 실시되었다. 삽목실험은 삽목용토별 발근정도, 발근촉진제로 이용되고있는 NAA, IAA, IBA의 적정침지농도와 침지시간, 삽수조제방법에 따른 발근력 차이에 관해 조사하였다. 실험결과를 요약하면 다음과 같다. 1. 감차의 삽목용토로는 모래와 perlite가 적절하였다. 2. NAA, IAA, IBA의 삽목발근촉진효과는 발근율, 발근수, 근장에서 인정되었다. 3. 발근촉진물질의 효과는 처리농도와 시간에 따라 차이가 있었으며, NAA는 25ppm∼120분처리구, IAA는 50ppm∼30분처리구, IBA는 25ppm∼30분처리구에서 가장 좋았다. 4. 가장 적절한 삽수의 길이와 직경은 8㎝와 3.5㎜였다. 5. 삽수의 잎수에 따른 발근율은 3매의 경우 60%였으나, 6매로 증가시킴에 따라 90%로 향상되었다. 6. 녹지삽의 발근율은 80%, 숙지삽의 발근율은 20%였다. This study was carried out to investigate the asexual propagation methods of the Hydrangea serrata as landscape plant and tea materials. Cutting experiments were conducted to determine the most suitable rooting medium, the method of cutting preparation, suitable concentration and dipping time of NAA, IAA and IBA. The results are summarized as follows: 1. Sand and perlite are suitable rooting medium for the cutting. 2. Treatment of NAA, IAA and IBA solution was effective compared with control in rooting percentage, rootlet number and root length. 3. The significant effects of concentration and dipping time were 50ppm∼120minute in NAA, 50ppm∼30minute in IAA and 25ppm∼30minute in IBA respectively. 4. The most suitable cutting length and cutting diameter were 8cm and φ3.5mm. 5. The rooting percentage of cutting increased from 60% to 90% by increasing the number of leaves attached to cuttings 3 to 6. 6. The rooting percentage of softwood was 80%, but the rooting percentage of hardwood was 20%.