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총체적 학습법을 통한 취업 대비 기사 자격증 취득을 위한 특별 학습 지도
육 철,노용택,김대유,이상희 永同工科大學校 1996 硏究論叢 Vol.2 No.1
본 연구는 생명공학부 유전공학전공 2, 3학년을 대상으로 진행된 특별 학습 program으로 취업 대비 목적의 국가 기술 자격증 취득을 위한 특별 학습 지도와 산업 현장 이해를 돕기 위한 현장 교육을 목적으로 추진되었다. 본 연구의 주요 추진 상황으로는 정규 강의와 별도로 소규모 grouping을 통한 특별 학습 실시, 산업체 현장 견학 및 실습, 기사 시험을 대비한 집중 학습 program실시, 하계 방학 특강, 취업에 필요한 제반 교육 등을 실시하였다. 주요 실적으로는 식품 제조 기사 1차시험에서 60%의 합격률을 보였으며 6회에 걸친 산업체 현장 견학과 1회의 산업체 실습을 통하여 현장에 대한 이해도를 높임과 동시에 관련 산업체에 영동공대의 인지도를 높여 주었다. 그리고 본 연구의 가장 중요한 성과로는 목표 설정과 동기 부여를 통하여 학생들 스스로가 학습 성취감을 느낄 수 있었던 점이라 생각된다. This research is of a special topics course(STC) prepared for the sophomore and junior students of the Faculty of Life Science and Engineering(majoring in genetic engineering). It consists of two major programs to improve opportunities for employment of students after graduation: one is a special study program for national technical qualification certification and the other is a field trip and practical experience to learn about industry firsthand. This course included special programs such as special group study in small-sized groups of 2-5 persons, tours and practice at industrial plants and laboratories, intensive study programs prepared for the national technical qualification examination, special lectures during the summer vacation and general education designed to increase opportunities for employment of the students after graduation, in addition to the normal lectures. With the fulfillment of this special topics course, 60% of students who participated in the program succeeded in the national technical qualification examination for food processing, and the students 'understanding about processing and facilities at plants was increased through a total of 7 plant tours and practice which also helped the acknowledgement of YIT to the relevant industries.
STS 학습 지도법에 의한 유전공학 전공의 취업률 향상에 관한 연구
김대유,노용택,육철,이상희 永同大學校 1997 硏究論叢 Vol.3 No.1
STC 교육은 학생들이 학교를 떠나 장차 사회에서 유용하게 쓸 수 있는 경험을 쌓게 하는 방법으로서, 본 연구는 이와 같은 STC 학습법을 활용하여 생명공학부 유전공학전공 2, 3, 4학년 학생들을 대상으로 진행된 취업 대비 기사 자격증 취득을 위한 특별 학습 지도와 산업 현장 이해를 돕기 위한 현장 교육을 목적으로 추진되었다. 본 연구의 주요 추진 상황으로 정규 강의와 별도로 소규모 grouping을 통한 특별 학습 실시, 산업체 견학 및 대학원 실험실 실습, 기사 시험을 대비한 집중 학습 program실시, 하계 방학 특강, 취업에 필요한 제반 교육 들을 실시하였다. 주요 실적으로는 식품 제조 기사2급 2차 시험에 생명공학부 유전공학전공 4학년 학생 5명이 응시하여 5명 전원이 합격한 것을 비롯하여 총 8명이 기사 자격증을 취득하였고, 여러 차례 현장 학습을 통하여 현장에 대한 감각과 이해력을 높였던 점을 들 수 있다. 그리고 본 연구의 가장 중요한 성과로는 목표 설정과 동기 부여 및 목표달성을 통하여 학생들 스스로가 학습 성취도를 고취시킬 수 있었던 점이라 생각된다. STC program is a strategy of preparatory educations for students to gain useful experiences for social activities after graduation. In this STC study, special programs to pass the national technical qualification certification and field trips and practical experiments to understand the actual conditions of industry and society first-hand, are carried out through STS education method. This course included special programs besides the regular lectures such as special group study in small-sized group, tours at industrial plants and laboratories, practical experiments in graduate school, intensive study programs prepared for the national technical qualification examination, special lectures during the summer vacation and general educations for employment after graduation. In this program, it was achieved that 5 senior students passed the national technical qualification examination of food manufacturing, totally 8 students aquired the national technical qualification certification and students majoring in genetic engineering of the faculty of life science and engineering learned the feeling and appreciations of industry and society through several field learning. Conclusively, the main achievement of STS program is that students for themselves developed the learning activity through setting the goals, giving incentives, and reaching the goals voluntarily.
Time Frequency Domain Reflectometry 기법을 이용한 Coaxial Cable에서의 결함 감지 및 추정
송은석,신용준,최덕선,육종관,박진배,Powers, Edward J. 한국항행학회 2003 韓國航行學會論文誌 Vol.7 No.1
본 논문에서는 도선사에서 발생하는 결함 위치와 이상 유무를 감지하는 새로운 고분해능 반사측정법인 시간-주파수 영역반사측정법 (TFDR, Time-Frequency Domain Reflectometry)을 제안하였다. 고전적인 반사측정법들은 단지 시간 또는 주파수의 한 영역에서 분석되어져 왔으나, 본 논문에서 제시한 TFDR은 도선의 결함 위치와 이상 유무를 발견하기 위해 과도신호의 시간과 주파수 영역의 정보를 동시에 이용할 수 있는 시간-주파수 분석기법으로 특성화하였다. TFDR의 기준신호 설계는 측정 케이블의 물리적 성질들을 고려하여 주파수 밴드를 결정하며, 도선의 결함감지와 추정은 시간-주파수 상호상관관계 함수에 의해 이루어진다. TFDR 시스템을 이용하여 여러 결함 상태를 가진 실제 coaxial cable (RG-142, RG-400)에 대해 실험하였고 정확성을 입증하기 위해 TDR (Time Domain Reflectometry) 장비와 성능은 비교하였다. 본 논문에서는 TFDR이 TDR보다 작은 오차로 결함을 찾아냄을 나타내고 있으며, 측정된 정확도는 TFDR의 오차율이 0.5%이하로 TDR (54750A/54754A) 장비보다 성능이 월등히 우수하다는 것을 알 수 있다. In this paper, a new high resolution reflectometry scheme, time-frequency domain reflectometry (TFDR), is proposed to detect and locate fault in wiring. Traditional reflectometry methods have been achieved in either the time domain or frequency domain only. However, time-frequency domain reflectometry utilizes time and frequency information of a transient signal to detect and locate the fault. The time-frequency domain reflectometry approach described in this paper is characterized by time-frequency reference signal design and post-processing of the reference and reflected signals to detect and locate the fault. Design of the reference signal in time-frequency domain reflectometry is based on the determination of the frequency bandwidth of the physical properties of cable under test. The detection and estimation of the fault on the time-frequency domain reflectometry relies on the time-frequency domain reflectometry is compared with commercial time domain reflectometry (TDR) instrument. In these experiments provided in this paper, TFDR locates the fault with smaller error than TDR. Knowledge of time and frequency localized information for the reference and reflected signal gained via time-frequency analysis, allows one to detect the fault and estimate the location accurately.
김은희,김철규,이순교,김순덕,이혜옥,권정순,이경미,이민미,심순미,유용만,신종식,강은희,이상일,김병식,오성태,육정환,박수길 한국의료QA학회 2003 한국의료질향상학회지 Vol.10 No.2
Background : Gastric cancer is the most common malignant tumor in Korea. surgical operation is one of the major treatment modalities for gastric cancer patients. Therefore, gastrectomy is one of the most common procedures in General Surgery. There were variation in length of hospital stay and medical treatment for gastrectomy between three surgeons at Asan Medical Center. Clinical pathways have received considerable attention as a tool for recucing the medical practice variation, increasing the efficiency of care process, and improving the quality of care. The aim of this study was to evaluate the effect of a clinical pathway for gastrectomy in gastric cancer patients. Methods : The clinical pathway for gastrectomy was developed and implemented by a multidisciplinary group in Asan Medical Center. A computerized clinical pathway program was developed and revised after a pilot test. A total of 145 patients underwent gastrectomy by three surgeons at Asan Medical Center. We compared the length of hospital stay, patient satisfaction, and unplanned readmission rate between the pre-pathway group(n=67) and the post-pathway group(n=78). We also investigated the degree of satisfaction among the physicians and nurses who were main end-users of the clinical pathway. Results : The clinical pathway was applied to all target patients. The average length of hospital stay was shortened from 12.7days to 10.6days(p<0.01). The degree of patient satisfaction with the care process changed from 90.3% to 89.2% after the implementation of the clinical pathway, but the difference was of satistically significant(p=0.761). Unplanned readmission rate was 2.9% in the pre-pathway group. More than 90% of physicians and nurses answered that the clinical pathway had been a useful tool in their medical practice. Conclusions : The findings of the study demonstrated that implementation of the clinical pathway for gastrectomy produced substantial reduction in the length of hospital stay while improving the quality of patient outcomes. The computerized clinical pathway program can be used as one of the powerful patient management tools for reducing the practice variations and increasing the efficiency of care process in Korea hospital settings.
Proteomic studies of putative molecular signatures for biological effects by Korean Red Ginseng
Yong Yook Lee,Hwi Won Seo,Jong-Su Kyung,Sun Hee Hyun,Byung Cheol Han,Songhee Park,Seung-Ho So,Seung Ho Lee,Eugene C. Yi 고려인삼학회 2019 Journal of Ginseng Research Vol.43 No.4
Background: Korean Red Ginseng (KRG) has been widely used as an herbal medicine to normalize andstrengthen body functions. Although many researchers have focused on the biological effects of KRG,more studies on the action mechanism of red ginseng are still needed. Previously, we investigated theproteomic changes of the rat spleen while searching for molecular signatures and the action mechanismof KRG. The proteomic analysis revealed that differentially expressed proteins (DEPs) were involved inthe increased immune response and phagocytosis. The aim of this study was to evaluate the biologicalactivities of KRG, especially the immune-enhancing response of KRG. Methods: Rats were divided into 4 groups: 0 (control group), 500, 1000, and 2000 mg/kg administrationof KRG powder for 6 weeks, respectively. Isobaric tags for relative and absolute quantitation was performedwith Q-Exactive LC-MS/MS to compare associated proteins between the groups. The putativeDEPs were identified by a current UniProt rat protein database search and by the Gene Ontologyannotations. Results: The DEPs appear to increase the innate and acquired immunity as well as immune cell movement. These results suggest that KRG can stimulate immune responses. This analysis refined our targetsof interest to include the potential functions of KRG. Furthermore, we validated the potential moleculartargets of the functions, representatively LCN2, CRAMP, and HLA-DQB1, by Western blotting. Conclusion: These results may provide molecular signature candidates to elucidate the mechanisms ofthe immune response by KRG. Here, we demonstrate a strategy of tissue proteomics for the discovery ofthe molecular function of KRG.
Dynamic Analysis and Structural Optimization of a Fiber Optic Sensor Using Neural Networks
Yong-Yook Kim,Rakesh K. Kapania,Eric R. Johnson,Matthew E. Palmer,Tae-Kyu Kwon,Chul-Un Hong,Nam-Gyun Kim 대한기계학회 2006 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.20 No.2
The objective of this work is to apply artificial neural networks for solving inverse problems in the structural optimization of a fiber optic pressure sensor. For the sensor under investigation to achieve a desired accuracy, the change in the distance between the tips of the two fibers due to the applied pressure should not interfere with the phase change due to the change in the density of the air between fibers. Therefore, accurate dynamic analysis and structural optimization of the sensor is essential to ensure the accuracy of the measurements provided by the sensor. To this end, a normal mode analysis and a transient response analysis of the sensor were performed by combining commercial finite element analysis package, MSC/NASTRAN, and MATLAB. Furthermore, a parametric study on the design of the sensor was performed to minimize the size of the sensor while fulfilling a number of constraints. In performing the parametric study, the need for a relationship between the design parameters and the response of the sensor was fulfilled by using a neural network. The whole process of the dynamic analysis using commercial finite element analysis package and the parameter optimization of the sensor were automated within the MATLAB environment.
배양된 제대정맥내피세포에서 중증자간전증환자 혈청이 내피세포 생육 및 Endothelin-1합성에 미치는 영향
김용욱(Yong Yook Kim),나욱렬(Wook Yull Na),이종건(Jong Kun Lee),이영(Young Lee),백은정(Eun Jeong Baik),나종구(Jong Gu Rha),김사진(Sa Jin Kim),이형근(Hyung Gun Lee),신종철(Jong Chul Shin),김수평(Soo Pyung Kim) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.7
목적 : 중증자간전증 환자의 혈청이 배양된 제대정맥 내피세포의 생육과 endothelin-1의 합성에 미치는 영향을 알아보고자 하였다. 연구방법 : 합병증이 없이 분만한 정상 임산부로 부터 제대정맥 혈관 내피세포를 얻어 정상임신부의 혈청 또는 중증 자간전증 환자의 혈청과 함께 생체외 배양을 하여, 비색 MTT법으로 제대정맥 혈관내피 세포의 생육에 대한검사, endothelin-1의 합성에 미치는 영향을 조사하였고, 동시에 정상임신부 및 자간전증 환자 혈장내의 endothelin-1의 농도를 측정하였다. 결과 : 1. 비색 MTT 측정에서 환자 또는 정상 산모의 혈청과 24시간 동안 배양시킨 배양액의 흡광도는 각각 0.0837±0.0129와 0.0718±0.0078로 두군간에 유의한 차이가 없었으며, 48시간 동안 배양시킨 실험에서 흡광도는 0.1268±0.0186과 0.1133±0.0103으로 두군간에 유의한 차이가 없었다. 2. 정상임신부의 혈청내 endothelin-1의 농도는 22.66±8.6 fmol/ml, 중증자간전증 환자의 혈청내 endothelin-1의 농도는 49.98±25.27 fmol/ml로 중증자간전증 환자에서 유의하게 높았다.(P<0.05) 3. 정상임신부의 형청을 가한 경우 endothelin-1의 함성량은 37.52±18.41 fmol/ml이며 중증자간전증 환자 혈청을 가한 경우는 97.58±53.64 fmol/ml 로 중증자간전증 환자의 혈청은 endothelin-1의 함성을 유의하게 증가시켰다.(P<0.05) 결론 : 자간전증 환자의 혈청은 혈관내피세포의 생육에는 별로 영향을 미치지 않았으며 선택적으로, 특이하게 내피세포기능중 Endothelin-1의 합성을 현저히 증가시켰다. Objectives: In order to assess the effects of sera from severe preeclamptic patients on endothelial cell viability in vitro and endothelin-1 synthesis in cultured human umbilical vein endothelial cells.Methods: The cultured human umbilical vein endothelial cells were incubated with media containing 10% sera from women with either preeclamptic patients or normal pregnancies for 24 hours or 48 hours. After then, their viability was measured by colorimetric MTT{3-(4,5-dimethylthiazol-2yl)2,5-diphenyl tetrazolium bromide} assay and their production of endothelin-1 was measured. We also measured the serum levels of endothelin-1 level in sera obtained from the normal and severe preeclamptic pregnancies. Results: The calorimetric MTT assay revealed that after 24 hours, the absorbances in the media treated with normal pregnancies and severe preeclampsia sera were 0.0718±0.0078 and 0.0837±0.0129, respectively and after 48 hours, they were 0.1133±0.0103 and 0.1268±0.0186, respectively. Serum obtained from severe preeclampsia did not affect endothelial cell viability. 2. The serum mean levels of endothelin-1 in normal and severe preeclamptic pregnancies were 22.66±8.6 fmol/ml and 48.98±25.27 fmol/ml. The mean level in preeclamptic sera was significantly higher than that of normal pregnant women. (P<0.05) 3. After 24 hours, the mean amount of endothelin-1 stimulated by normal pregnant and severe preeclamptic sera were 37.52±18.41 fmol/ml and 97.58±53.64 fmol/ml, respectively. The mean amount of endothelin-1 in preeclamptic sera-treated cells was significantly higher than that of normal pregnant sera-treated cells. (P<0.05). Conclusion: The sera from severe preeclamptic women do not affect cell viability but act selectively on specific activation of their function such as endothelin-1 production. And it is necessary that the identification and isolation of the putative serum factor(s) will be performed to resolve the pathogenesis in future.