헬리코박터 파이로리 균 진단용 ^13C-요소 캅셀의 개발

용철순,김용일,김지만,강성훈,권기철,이종달,김종국,사홍기,최한곤 영남대학교 약품개발연구소 2002 영남대학교 약품개발연구소 연구업적집 Vol.11 No.-

The purpose of this study was to develop a new ^13C-urea-containing capsule for diagnosis of H.pylori. The urea-containing capsules were prepared with various diluents such as polyethylene glycol (PEG), microcrystaline cellulose, sodium lauryl sulfate and citric acid. The dissolution test, ^13C-urea breath test and stability test were then performed on the capsules. Microcrystalline cellulose and sodium lauryl sulfate retarded the initial dissolution rates of urea. However, PEG increased the initial dissolution rates of urea. Furthermore, two formulae composed of PEG,[^13C-urea/PEG (38/1.9 mg/cap)] and [^13C-urea/PEG (38/1.9/1.9 mg/cap)] had the maximum DOB value. about 16 at 20 min, while the formula composed of only 38 mg ^13C-urea had the maximum DOB value at 30 min. The results indicated that PEG improved the sensitivity of ^13C-urea in the human volunteers. The capsule [^13C-urea/PEG (38/1.9 mg/cap)] was stable for at least six months in 25 and 37℃. Thus, a PEG-containing capsule, [^13C-urea/PEG (38/1.9 mg/cap)] would be a more economical, sensitive and stable perparation for diagnosis of H. pylori.

헬리코박터 파이로리 균 진단용 ^13C-요소 캅셀의 개발

용철순,김용일,김지만,강성훈,권기철,이종달,김종국,사홍기,최한곤 한국약제학회 2002 Journal of Pharmaceutical Investigation Vol.32 No.1

The purpose of this study was to develop a new ^13C-urea- containing capsule for diagnosis of H. pylori. The urea-containing capsules were prepared with various diluents such as polyethylene glycol (PEG), microcrystalline cellulose, sodium lauryl sulfate and citric acid. The dissolution test, ^13C-urea breath test and stability test were then performed on the capsules. Microcrystalline cellulose and sodium lauryl sulfate retarded the initial dissolution rates of urea. However, PEG increased the initial dissolution rates of urea. Furthermore, two formulae composed of PEG, [^13C-urea/PEG (38/1.9 mg/cap)] and [^13C-urea/PEG/citric acid (38/1.9/1.9 mg/cap)] had the maximum DOB value, about 16 at 20 mim, while the formula composed of only 38 mg ^13C-urea had the maximum DOB value at 30 min. The results indicated that PEG improved the sensitivity of ^13C-urea in the human volunteers. The capsule [^13C-urea/PEG (38/1.9 mg/cap)] was stable for at least six months in 25 and 37℃. Thus, a PEG-containing capsule, [^13C-urea/PEG (38/1.9 mg/cap)] would be a more economical, sensitive and stable preparation for diagnosis of H. pylori.

중국 靑島의 한국 산업 이전 유치효과 향상방안 연구 : 靑島 진출 한국 기업의 투자동기 분석을 중심으로

徐永輝,全冬梅 신라대학교 경제경영연구소 2007 경제경영연구 Vol.8 No.-

This study analyzed the main motive of Korean firm's FDI into Qingdao of China in order to improve the effects of attracting Korean firm's FDI to Qingdao. This study first researched the literatures and studies on FDI motive systematically. Then classified it into two groups(low product's costs and Chinese domestic market) and measured Korean firm's features of real motive using survey data of (Korean) firm-level in Qingdao. Finally discussed and showed suggestions for Improving effects of attracting Korean firm's FDI to Qingdao.

황강의 저서성 대형무척추동물의 군집구조에 관한 연구

류성만,전영태,이종욱,차진열 嶺南大學校 基礎科學硏究所 1997 基礎科學硏究 Vol.17 No.-

The present study was conducted to determine the community structure in Whang river based on the benthic macroinvertebrates. The survey area included eight sites in Whang river and two sites in Nakdong river and the study was carried out from March of 1995 to February of 1996. The result are as follows; (1) Benthic mactoinvertebrates are composed of a total of 200 species including 114 genera, 71 families, 21 orders, 7 classes in five phyla. A total of 200 species was found in Whang river, however only 66 species were recorded in Nakdong river. 2) Species frequency was different depending on the study area. It ranged from 84-112 species in the upper stream(site 1 to 6) to 71-75 species in the lower stream(site 7 to 8) and 41-58 species in the Nakdong river(site 9 to 10). Taxa with highest species frequency were aquatic insecta. 3) Average number of individuals was 1656.5/0.5㎡ in the whole study aera. Inividual number was variable from 53/0.5㎡ at the site 8 to 296.8/0.5㎡ at the site 4. Taxa with highest individual species frequency were aquatic insecta. 4) Trichoptera and Ephemeroptera were dominant in upper stream, while Chironomidae was the most aboundant group in the lower stream. 5) Average dominance(DI), species richness(RI), species diversity(H'), and evenness(J') were 0.68, 2.71, 3.10 and 0.71, respectively, in the whole study area. The biotic indices in Whang river were relative higher than that of Nakdong river. 6) Functional feeding groups were collectors and shredder at site 1 to 6, filterer at site 7 to 10.

삼천지의 곤충상

이종욱,류성만,서경인,전영태,배찬영 嶺南大學校 基礎科學 硏究所 1998 基礎科學硏究 Vol.18 No.-

We studied insect fauna in the Samchun-impoundment during the period of from September 1997 to August 1998. The total number of insect taxa are composed to 95 species in 86 genera, 39 families and 8 orders in this examination.

Physicochemical Characterization and In Vivo Evaluation of Thermosensitive Diclofenac Liquid Suppository

Yong, Chul-Soon,Choi, Young-Kwon,Kim, Yong-Il,Park, Byung-Joo,Quan, Qi-Zhe,Rhee, Jong-Dal,Kim, Chong-Kook,Choi, Han-Gon The Pharmaceutical Society of Korea 2003 Archives of Pharmacal Research Vol.26 No.2

Liquid suppository systems composed of poloxamers and bioadhesive polymers were easy to administer to the anus and mucoadhesive to the rectal tissues without leakage after the dose. However, a liquid suppository containing diclofenac sodium could not be developed using bioadhesive polymers. since the drug was precipitated in this preparation. To develop a liquid suppository system using sodium chloride instead of bioadhesive polymers, the physicochemical properties such as gelation temperature, gel strength and bioadhesive force of various formulations composed of diclofenac sodium, poloxamers and sodium chloride were investigated. Furthermore, the pharmacokinetic study of diclofenac sodium delivered by the liquid suppository was performed. Diclofenac sodium significantly increased the gelation temperature and weakened the gel strength and bioadhesive force, while sodium chloride did the opposite. The liquid suppositories with less than 1.0% of sodium chloride, in which the drug was not precipitated, were inserted into the rectum without difficulty and leakage. Furthermore, liquid suppository gave significantly higher initial plasma concentrations and faster Tmax of diclofenac sodium than did solid suppository, indicating that drug from liquid suppository could be absorbed faster than that from solid one in rats. Our results suggested that a thermosensitive liquid suppository system with sodium chloride and poloxamers was a more physically stable, convenient and effective rectal dosage form for diclofenac sodium.

THE DEVELOPMENT OF CULTURAL AND CREATIVE TORUISM: The MEASURING OF DESTINATION ATTRIBUTES ASSOICATED WITH EXPERIENCES, CULTURAL MEMORIES AND CONTATS

Yong-Quan Li,Chih-Hsing Liu,Wen-Qi Ruan 글로벌지식마케팅경영학회 2018 Global Marketing Conference Vol.2018 No.07

Cultural tourism has always been recognized as the heart of the new tourism trend, and Chinese culture has received increasing attention worldwide. Cultural tourism to China delivers the values of traditional Chinese culture and provides a satisfying authentic experience for tourists. Experience is an emotional reflection of tourists’ true feelings and evaluations during the tourism process and encompasses more than the delivery of a physical product or service. Experience involves creating unique memories of destinations and is inimitable of the individual sensitivity for special events. While these creative experiences have received increasing attention from marketing scholars and various industry practitioners in general product domains, the creative experience factors of tourism systems remain unexplored. Furthermore, although the matter of experience affects tourists’ behaviors and attitudes, little is known regarding how Chinese culture affects tourists’ creative experiences, destination attachments and memories. The effects of cultural contacts and creative experiences on destination attachment and roles of satisfaction and attitudes should be considered with respect to the development of cultural and creative tourism. This study proposes cultural contact as an important enabler of destination attachment. Moreover, we examine both how and when culture contacts enhance tourists’ destination attachments by considering two critical attributes as mediators, including creative experience (i.e., Escape and Recognition, Unique Involvement, Interactivity, Peace of Mind and Learning) and cultural memories. We also considered two elements of tourists’ behaviors (satisfaction and attitude) as important contingencies. We test and integrate our concepts of a moderated mediation framework using the cultural and creative tourism from a sample of 651 tourists. We discuss how our empirical results extend Chinese culture, creative experience, and destination attachment research and provide the study’s theoretical and managerial implications.

Ephemeroptera (Insecta) Fauna of Northeast China

Quan, Yong-Tai,Bae, Yeon-Jae,Jung, Jong-Chul,Lee, Jong-Wook 한국응용곤충학회 2002 Insecta Koreana Vol.19 No.3

A comprehensive literature review and examination of mayfly materials from Northeast China resulted in the recognition of 65 species, 28 genera, and 12 families of Ephemeroptera. Checklist, original reference sources, larval diagnoses, measurements, materials examined, distributions, and taxonomic remarks are provided. Macro-photos of larval body (dorsal view) and line-drawings of larval key characters are also provided.

Ephemeroptera (Insecta) Fauna of Northeast China

Quan, Yong-Tai,Bae, Yeon-Jae,Jung, Jong-Chul,Lee, Jong-Wook Korean Society of Applied Entomology 2002 INSECTA KOREANA Vol.19 No.3

A comprehensive literature review and examination of mayfly materials from Northeast China resulted in the recognition of 65 species, 28 genera, and 12 families of Ephemeroptera. Checklist, original reference sources, larval diagnoses, measurements, materials examined, distributions, and taxonomic remarks are provided. Macro-photos of larval body (dorsal view) and line-drawings of larval key characters are also provided.

Experimental evaluation of aerodynamic damping of square super high-rise buildings

Yong Quan,Ming Gu,Yukio Tamura 한국풍공학회 2005 Wind and Structures, An International Journal (WAS Vol.8 No.5