Holmium:YAG laser를 이용한 요관경하쇄석술의 초기 경험 : 기존의 쇄석술과의 결과 비교

구경완,노용수,김홍섭,양상국,나공찬 건국대학교 의과학연구소 2003 건국의과학학술지 Vol.13 No.-

Purpose: Holmium:YAG lasertripsy for the 33 patients with lower ureteral calculi compared the outcome with other results using Lithoclast and ultrasonic lithotripsy. Materials and Methods: Thirty-three patients with symptomatic urinary calculi underwent Holmium:YAG lasertripsy from March 1999 to December 2000. Twelve patients were treated with Ultrasonic lithotripsy and twenty-one patients with Lithoclast lithotripsy from April 1997 to October 1999. All calculi of the above patients were located in their lower ureters. The size of ureter stones was ranged from 3.5 mm to 12 mm (mean 6.54 mm). Results: The age of the patients ranged was from 19 to 62 years (me~n 35.7 years). After a single ureteroscopic lasertripsy calculi were conlpletely cleared in 83 % of the cases for the patients with lower ureter calculi. The immediate complications of lasertripsy were gross hematuria, fever, and flank pain. However in the long term follow up (up to 3 months after the procedures) there were no further complications, such as, vesicoureteral reflux or ureteral stricture. In other two lithotripsies Lithoclast and Ultrasonic lithotripsy accomplished calculi were completely cleared in 71 % and 74 % of cases respectively. But Holmium:Y AG lasertripsy is cleared in 94 % effectiveness. Holmium:Y AG lasertripsy is more effective than two other methods compared by stratified analysis that unmasking from confounding factors such as impacted situation. Conclusions: Lasertripsy with Holmium:Y AG laser is considered effective and safe procedure for the lower urinary calculi lithotripsy (Ultrasonic, Lithoclast).

東醫寶鑑을 중심으로 살펴 본 男女

구교성,이용태 동의대학교 한의학연구소 2002 동의한의연구 Vol.6 No.-

In terms of Yin and Yang theory, Man is Yang but Woman is Yin, in terms of Fire and Water, Man is Fire but Woman is Water, in terms of Heaven and Earth theory, Man is Heaven but Woman is Earth, in terms of Ki and Hyul theory, Man is Ki but Woman is Hyul, in terms of Jung and Hyul theory, Man is Jung but Woman is Hyul, in terms of Give and Take theory, Man is Giver but Woman is Taker, in terms of Right and Left theory, Man is Left but Woman is Right in terms of Upper and Lower sides theory, Man is the Upper side but Woman is the Lower side, in the theory of the Physiological changes of age, Man changes at a multiple of 8 but Woman changes at a multiple of 7. Because of the clinical treatment, the difference between the Man and Woman in physiological or pathological state is very impotent, so in Hyunsang Medicine, doctors observe the changes of the genital organs that menstruation, leucorrhea, pregnancy, delivery, and the breast.

釜山市 交通容量과 路幅의 檢討 : Horld. M. Lewis 公式을 主로 하여

金容九 釜山工業大學 1967 論文集 Vol.5 No.-

May-Thurner Syndrome 환자의 좌측 하지 심부정맥혈전증 : Pigtail 카테터 회전을 이용한 치료의 효용성과 안전성 Lower Extremity Deep Vein Thrombosis of May-Thurner Syndrome

정구용,염차경,이주호,강병철 대한혈관외과학회 2004 Vascular Specialist International Vol.20 No.1

플루옥세틴 캅셀제의 지원자에 대한 생체이용율 및 대사율 비교

강원구,박용순,조규행,최준식,권광일 충남대학교 약학대학 의약품개발연구소 1998 藥學論文集 Vol.14 No.-

Fluoxetine is a nontricyclic antidepressant which blocks serotonin reuptake selectively. Its N-demethyl metabolite, norfluoxetine is also selective inhibitor of serotonin uptake. This study was carried out to compare the bioavailability of Myung-in fluoxetine (20 ㎎/cap with that of Prozac?. The bioavailability was conducted on 24 healthy volunteers who received a single dose (80 ㎎) of each drug in the fasting state, in a randomized balanced 2-way crossover design. After dosing, serial blood samples were collected for a period of 48 hours. plasma was analyzed for fluoxetine and norfluoxetine by a sensitive and validated HPLC assay. The major pharmacokinetic parameters (AUC_0-48hr, Cmax, Tmax. AUC_inf.. MRT. T_1/2. Vd and Cl) were clculated from the plasma fluoxetine concentration-time data of each volunteer. The microcomputer program. "WinNonlin' was used for compartmental analysis. A two-compartment model with first-order inpot, first-order output and no lag time was chosen as the most appropriate phamacokinetic model. The data were best described by using a weighting factor of 1/y^2. Though the plasma fluoxetine concentrations of Myung-in fluoxetine were higher than those of Prozac® at all observed time from 7.9% to 16.9% (P<0.05 at 6, 7 and 10 hr), the bioavailability of Myung-in fluoxetine appeared to be bioequivalent with that of Prozac®. There were no statistical significant differences between the two drugs in al pharmacokinetic parameters including AUC_0-48hr of norfluoxetine.

황금배 品種의 單一品種 果園을 위한 콩배 受粉樹 移用에 관한 硏究

沈慶久,河有美,李俊馥,崔勇洵 성균관대학교 생명과학자원연구소 1994 生命資源科學硏究 Vol.1 No.1

Fauriei pear(Pyrus fauriei Nakai) potentially useful as pollenizers in single-cultivar `Hwangkuembae' orchard was evaluated for their flowering times and pollen germination(%). Their efficiency in the setting of fruits following controlled pollinations on 'Hwangkuembae' at Fruit Tree Research Institute in Suwon was also examined. The obtained results are as followes ; (1) Flowering times of SKK 1 was from April 21 and that of them corresponded to that of 'Hwangkuembae'. (2) Pollen germination (%) of SKK 1 using as pollenizer of 'Hwangkuembae' was over 90%. Therefore Based on these factors, folwering times and pollen germination, SKK 1 was found to be promising as pollenizer for single-cultivar 'Hwangkuembae' orchard. (3) Percentage of fruit setting in 'Hwangkuembae' pollinated with Fauriei pear showed 71.9%. And there was no statistically significant difference in the fruit diameter(cm), fruit height(cm), fruit index, fruit weight (g), soluble solid(˚BX), acidity(pH), and fruit hardness (kg/㎠) of 'Hwangkuembae' pollinated with Fauriei pear (4) Percentages of fruit setting in 'Hwangkuembae' pollnated with Fauriei pear corresponding to flowering times of 'Hwangkuembae', was 871.9% and no statistically significant difference in fruit quality. On the bases of flowering times, pollen germination(%), efficient fruit set(%), and no statistically significant difference in fruit quality, Fauriei pear(Pyrus fauriei Nakai) is promising as pollenizers for single-cultivar 'Hwangkuembae' orchard.

企業公示制度에 대한 硏究

金容九,張仁植 群山大學校 法學硏究所 1997 法學硏究 Vol.1 No.-

Korean capital markets have made remarkable progress, due to the government policy on promoting the capital makets. Nowadays, many enterprises are urgently requested to give their public benifits to the public, while they fulfill their pursuit of profits and manage the products of a nation as well. In capitalism, for the purpose of the protection of the consumers' earnings, the enterprises' disclosure systems must be encouraged to be legislatively opened to the public. In other words, the details for the disclosure, the enactment of a law for the protection of consumers, the compensation procedures, the foundation of the organization for the consumers, etc. are urgently needed. This thesis aims to give the maximum benifits to the investors and the persons involved by opening the information of tile enteprises to the public. The enterprises' disclosure systems, which is based on the political, economic, social, and legal situations of a nation, need the many-sided investiga -tions for the reasonablity. To effectively use the systems to open the enterprises' information, including the transaction-oriented information as well as the past information, the reasonable disclosure systems will have to be drawn up.

질내투여 인정장(人精漿)의 인정자(人精子) 및 면양적혈구에 대한 면역반응 억제작용

이헌구,김용탁,하대유 大韓免疫學會 1987 大韓免疫學會誌 Vol.9 No.1

A number of evidence has been accumulated to show that human seminal plasma (HSP) can suppress the immune responeses in vitro and in vivo. Several immunosuppressive factors have been identified from HSP and it has been proposed that these factors play a critical role in preventing sensitization of females to spermantigens after insemination. The purpose of the present study is to answer the q question whether HSI' is able to suppress in vivo immune responses induced by some antigens such as human sperms and sheep red blood cells(SRBC) which are introduced into the vagina of females. In this study the author used an experimental model in which mice were immunized intravaginally with human sperms and SRBC, and delayed-type hypersensitivity reacion (DTH) to these antigens was eva- luated by footpad swelling reaction. Repeated simultaneous intravaginal administrations of HSP with human sperms or SRBC significantly suppressed the DTH but failed to suppress the antibody formation to these antigens. However, intravaginal administration of a high molecular weigt fraction(G― 200 F, greater than 200 KD) which was partially purified by ammonium sulfate precipitation, DEAE- cellulose and Sephadex G -200 chromatography from HSP resulted in a significant suppression of DTH as well as antibody formation to SRBC. Furthermore, when various concentrations of G―200 F were ad-ministered intraperitoneally, a dose-dependent suppression of both DTH and antibody formation to SR BC was observed. These results provide the evidence that in vivo immunosuppressive activity of HSP is mediated by a high molecular weight fraction of greater than 200 KD and strongly support the concept that HSP can prevent sensitization of females to sperm antigens after insemination.

事實上理事의 法理에 관한 硏究

金容九 群山大學校 法學硏究所 1999 法學硏究 Vol.3 No.-

직업적 연폭로에서 혈중 연량 수준에 따른 선별검사로서의 혈중 ZPP 검사의 타당도

한구석,안현철,김용배,리갑수,김화성,황규윤,장봉기,이성수,안규동,이병국 순천향대학교 산업의학연구소 1999 순천향산업의학 Vol.5 No.1

In order to evaluate the validity of current screening criteria of lead exposure and to provide effective information for the better health management of lead workers, author investigated the interrelationship between blood lead and blood zinc protoporphyrin(ZPP) and evaluate the validity of blood zinc protoporphyrin as the screening test and blood lead as gold standard of diagnostic test. The total of 2245 lead workers (male workers: 1982, female workers : 263) from 12 lead using industries were studied. Blood lead, ZPP, hemoglobin and hematocrit were selected as lead exposure variables. Personal information on sex, age and work duration were also checked. Blood lead was measured with flameless atomic absorption spectrometry (model: Hitachi 8100) using standard addition method. Blood ZPP was measured with portable hematoflurometer (model: Aviv 206). The results obtained were as follows: 1. The mean blood lead of all lead workers were 0.7±14.3㎍/㎗(Male: 31.0±14.4㎍/㎗, Female: 28.2±12.9㎍/㎗), whereas the mean blood ZPP of those were 68.1±47.5㎍/㎗(Male: 63.9±43.7㎍/㎗, Female: 100.1±61.0㎍/㎗). The mean value of hemoglobin and hematocrit of all lead workers were 14.5±1.5g/㎗(Male: 14.7±1.3g/㎗, Female: 12.3±1.2g/㎗) and 45.4±3.6(Male: 46.2±2.8, Female: 39.5±3.1) respectively. 2. Validity of test using blood zinc protoporphyrin as screening test for blood lead levels of 30㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 50 and 90 ㎍/㎗ of ZPP respectively, showing 50 and 60 ㎍/㎗ of ZPP for all lead workers. While those test for blood lead levels of 40㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 60 and 90 ㎍/㎗ of ZPP respectively, showing 60 ㎍/㎗ of ZPP for all lead workers, those test for blood lead levels of 50 and 60㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 60 or 70 and 100 ㎍/㎗ ZPP respectively, showing 60and 70 or 80 ㎍/㎗ of ZPP for all lead workers. 3. Predictive value of test using blood zinc protoporphyrin as the screening test for different blood lead levels of 30, 40, 50 and 60㎍/㎗ as gold standard of diagnostic test revealed that positive predictive value of screening test were decreased by the increase of blood lead level regardless of csreening criteria value ZPP and negative predictive value of screening test were increased accordingly regardless of screening criteria value of ZPP. On the other hand, within same blood lead level as a gold standard positive predictive values were inceased by the increase of screening criteria value of ZPP, whereas the negative predictive value were decreased accordingly by the the increase of screening criteria value of ZPP. 4. The correlation analysis of all lead workers among study variables revealed that CPbB and natural log transformation ZPP(LZPP) were better correlated with other variables and found to be better estimate than PbB and ZPP themselves. The age was correlated with all other variables, but the work duration was not. The correlation analysis of male and female workers among study variables revealed the same results with all lead workers. 5. The slope of simple linear regression of CPbB (independent variable) with ZPP in female workers(3.223)was steeper than in male workers(2.144). That of lead workers with work duration of less than 1 year was steeper than that of lead workers whose work duration was more than 1 year. But there was no slope difference between two groups divided by their work duration of 2 years less and more. The slope of simple linear regression of CPbB lead (independent variable)with ZPP in lead workers whose blood lead were higher than 30㎍/㎗and 40㎍/㎗ were steeper than those whose blood lead were less than 30㎍/㎗ and 40㎍/㎗. 6. The slope of simple linear regression of CPbB (independent variable) with ZPP in lead industries with low mean blood lead were less steeper than those with high mean blood lead. 7. The slope of simple linear regression of CPbB (independent variable) with LZPP in female workers(0.0308was steeper than in male workers(0.0253). That of lead workers with work duration of less than 1 year was steeper than that of lead workers whose work duration was more than 1 year. But where was no slope difference between two groups divided by their work duration of 2 years less and more. While the slope of simple linear regression of CPbB lead (independent variable) with LZPP in lead workers whose blood lead were hogher than 30㎍/㎗ was not steeper than those whose blood lead were less than 30㎍/㎗, there was no slope difference between two groups whose blood lead were less than 40㎍/㎗ and more than 40㎍/㎗. 8. The slope of simple linear regression of CPbB (independent variable) with LZPP in lead industries with low mean blood lead were less steeper than those with high mean blood lead, but the difference was not significant then that of CPbB and ZPP. With above results, it is recommended that the screening criteria value of ZPP should be down to 60-70㎍/㎗ from 100㎍/㎗ for male lead workers and screening criteria of ZPP for female lead workers was all right with current value of 100㎍/㎗. So it is recommended to make different screening criteria of ZPP for male and female workers like the hemoglobin and hematocrit screening criteria. It is also preferable to use CPbB and LZPP rather than uncorrected PbB and ZPP in the evaluation of lead exposure for lead workers.