Chinese patent herbal medicine (Shufeng Jiedu capsule) for acute upper respiratory tract infections: A systematic review and meta-analysis

Ying-ying Zhang,Ru-yu Xia,Shi-bing Liang,Xiao-yang Hu,Meng-yuan Dai,Yi-lin Li,Le-yi Zhao,Michael Moore,Yu-tong Fei,Jian-ping Liu 한국한의학연구원 2021 Integrative Medicine Research Vol.10 No.3

Background: Shufeng Jiedu capsule has been widely used in China for acute upper respiratory tract infections (AURTIs). The aim of this study was to evaluate its effectiveness and safety for AURTIs. Methods: Randomized controlled trials comparing SFJD with conventional drug for patients with AURTIs were included. Eight databases were searched from their inceptions to February 2021. Data was synthesized using risk ration (RR) or mean difference (MD) with their 95% confidence interval (CI). The primary outcome was resolution time of typical symptoms. Results: Twenty-five RCTs involving 3410 patients were included. SFJD in combination with conventional drug was associated with; in common cold shortening the duration of fever (MD −1.54 days, 95% CI [−2.15,−0.92], I2 = 80%, n = 385, 3 trials) and cough (MD −1.22 days, 95% CI [−1.52, −0.93]); in herpangina, shortening the duration of fever (MD -0.68 days, 95% CI [−1.15, −0.21], I2 = 68%, n = 140, 2 trials) and blistering (MD −0.99 days, 95% CI [−1.23, −0.76], n = 386, 3 trials); in acute tonsillitis and acute pharyngitis shortening the duration of fever (MD −1.13 days, 95% CI [−1.36, −0.90], I2 = 33%, n = 688, 7 trials) and sore throat (MD −1.13 days, 95% CI [−1.40, −0.86], I2 = 84.1%, n = 1194, 10 trials). SFJD also improving their cure rate with a range (1–5 days). No serious adverse events were reported. Conclusion: Low certainty evidence suggests that SFJD appears to shorten the duration of symptoms in AURTIs, improve cure rate and seems safe for application. However, high quality placebo controlled trials are warranted to confirm its benefit.

Preparation of 2D/2D g-C3N4/Ti3C2 MXene composites by calcination synthesis method for visible light photocatalytic degradation of tetracycline

Qiao Le-Le,Zhang Feng-Jun,Kai Chun-Mei,Liu Chao,Wang Ying-Rui,Oh Won-Chun 한국세라믹학회 2023 한국세라믹학회지 Vol.60 No.5

In this work, an ultrathin 2D/2D g-C3N4/Ti3C2 heterojunction was synthesized by direct calcination of a mixture of urea and multilayer Ti3C2 for photocatalytic degradation of tetracycline. Among them, urea is the precursor for the generation of g-C3N4 and generates gas to peel the multilayer Ti3C2 into fewer layers while reacting, solving the problem of low yield for the preparation of fewer layers of Ti3C2. The experimental results of tetracycline degradation under visible light showed that pure g-C3N4 (UCN) exhibited weak photoactivity; however, its photocatalytic performance was enhanced when Ti3C2 was coupled with g-C3N4. The best sample (5TC) could degrade 90.1% of tetracycline within 30 min. After four cycles of stability test, the photocatalytic performance did not change significantly, indicating that the prepared 2D/2D g-C3N4/Ti3C2 heterojunction possesses strong photocatalytic performance along with good stability.

Comparative Proteomic Analysis of Changes in the Bovine Whey Proteome during the Transition from Colostrum to Milk

Zhang, Le-Ying,Wang, Jia-Qi,Yang, Yong-Xin,Bu, Deng-Pan,Li, Shan-Shan,Zhou, Ling-Yun Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.2

Bovine whey protein expression patterns of colostrum are much different from that of milk. Moreover, bovine colostrum is an important source of protective, nutritional and developmental factors for the newborn. However, to our knowledge, no research has been performed to date using a comparative proteomic method on the changes in the bovine whey proteome during the transition from colostrum to milk. This study therefore separated whey protein of days 1, 3, 7 and 21 after calving using two dimension electrophoresis. Differentially expressed proteins at different collection times were identified using high-performance liquid chromatography in tandem with mass spectrometry (LC/MS) and validated by enzyme-linked immunosorbent assay (ELISA) in order to understand the developmental changes in the bovine whey proteome during the transition from colostrum to milk. The expression patterns of whey protein of days 1 and 3 post-partum were similar except that immunoglobulin G was down-regulated on day 3, and four proteins were found to be down-regulated on days 7 and 21 compared with day 1 after delivering, including immunoglobulin G, immunoglobulin M, albumin, and lactotransferrin, which are involved in immunity and molecule transport. The results of this study confirm the comparative proteomic method has the advantage over other methods such as ELISA and immunoassays in that it can simultaneously detect more differentially expressed proteins. In addition, the difference in composition of milk indicates a need for adjustment of the colostrum feeding regimen to ensure a protective immunological status for newborn calves.

Recovery of Ganoderic Acids from Ganoderma lucidum Mycelia by Macroporous Adsorption Resins

Ying-bo Li,Jia-le Wang,Jian-Jiang Zhong 한국생물공학회 2012 Biotechnology and Bioprocess Engineering Vol.17 No.2

In this work, the performance and adsorption characteristics of macroporous resins for the recovery and enrichment of ganoderic acid (GA)-Mk and GA-T from Ganoderma lucidum mycelia were systematically evaluated. ADS-8 resin displayed the best adsorption and desorption capacities among the tested resins based on batch experiments. The interaction between solute and ADS-8 resin at different temperatures was described in terms of Langmuir and Freundlich isotherms, and the equilibrium experimental data were well fitted to the two isotherms. Thermodynamic analysis indicated the exothermic and spontaneous nature of the adsorption process. The adsorption capacity of ADS-8 resin was found to depend strongly on the pH value of the initial solution. Dynamic adsorption and desorption tests were performed on an ADS-8 resin-packed column to obtain optimal parameters for recovering GA-Mk and GAT from G. lucidum extract. Under optimized conditions, a laboratory scale-up preparation of GA-Mk and GA-T was carried out. The contents of GA-Mk and GA-T were increased from 45 to 22 mg/g in the crude extract to 352and 141 mg/g in the final product with recovery yields of 90.1 and 72.2%, respectively. These results demonstrated that ADS-8 resin chromatography could act as a useful approach for obtaining ganoderic acids from G. lucidum mycelia.

The Extended S-O-R Model Investigating Consumer Impulse Buying Behavior in Online Shopping: A Meta-Analysis

LE, Trang Quang,WU, Wann-Yih,LIAO, Ying-Kai,PHUNG, Thuy Thi Thu Korea Distribution Science Association 2022 유통과학연구 Vol.20 No.2

Purpose: The online distribution channel has attracted the attention of retailers by potential impact on consumers' purchase intention. The objectives of this study are to provide an insight into how to encourage consumers' impulse buying behavior on commercial website as well as attempts to reveal factors that influence consumers' impulsive buying behavior in the online shopping environment. Research design, data and methodology: The research framework is based on the stimulus-organism-response (S-O-R) framework. The Meta-analysis method carried out the research, gathering data from 37 published studies. Results: The research findings suggest that intrinsic motivations such as perceived ease of use, perceived enjoyment, and online flow experience play a significant role in boosting consumers' hedonic value when buying and online. In addition, these findings help online retailers use appropriate marketing stimuli such as offering pricing incentives, promotion tactics, and improved communication effectiveness. Also, obtaining a better grasp of how to build a website to improve the consumer experience generally helps consumers feel the urge to buy impulsively and act without hesitation. Conclusions: This research confirms a direct positive relationship between marketing stimuli and hedonic shopping value, which may support an applied theoretical framework for future research and provide managerial implications for retailers in online distribution channels.

Combining Model-based and Heuristic Techniques for Fast Tracking the Global Maximum Power Point of a Photovoltaic String

Ji-Ying Shi,Fei Xue,Le-Tao Ling,Xiao-Fei Li,Zi-Jian Qin,Ya-Jing Li,Ting Yang 전력전자학회 2017 JOURNAL OF POWER ELECTRONICS Vol.17 No.2

Under partial shading conditions (PSCs), multiple maximums may be exhibited on the P-U curve of string inverter photovoltaic (PV) systems. Under such conditions, heuristic methods are invalid for extracting a global maximum power point (GMPP); intelligent algorithms are time-consuming; and model-based methods are complex and costly. To overcome these shortcomings, a novel hybrid MPPT (MPF-IP&O) based on a model-based peak forecasting (MPF) method and an improved perturbation and observation (IP&O) method is proposed. The MPF considers the influence of temperature and does not require solar radiation measurements. In addition, it can forecast all of the peak values of the PV string without complex computation under PSCs, and it can determine the candidate GMPP after a comparison. Hence, the MPF narrows the searching range tremendously and accelerates the convergence to the GMPP. Additionally, the IP&O with a successive approximation strategy searches for the real GMPP in the neighborhood of the candidate one, which can significantly enhance the tracking efficiency. Finally, simulation and experiment results show that the proposed method has a higher tracking speed and accuracy than the perturbation and observation (P&O) and particle swarm optimization (PSO) methods under PSCs.

Improved Global Maximum Power Point Tracking for Photovoltaic System via Cuckoo Search under Partial Shaded Conditions

Ji-Ying Shi,Fei Xue,Zi-Jian Qin,Wen Zhang,Le-Tao Ling,Ting Yang 전력전자학회 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.1

Conventional maximum power point tracking (MPPT) methods are ineffective under partially shaded conditions because multiple local maximum can be exhibited on power–voltage characteristic curve. This study proposes an improved cuckoo search (ICS) MPPT method after investigating the cuckoo search (CS) algorithm applied in solving multiple MPPT. The algorithm eliminates the random step in the original CS algorithm, and the conception of low-power, high-power, normal and marked zones are introduced. The adaptive step adjustment is also realized according to the different stages of the nest position. This algorithm adopts the large step in low-power and marked zones to reduce search time, and a small step in high-power zone is used to improve search accuracy. Finally, simulation and experiment results indicate that the promoted ICS algorithm can immediately and accurately track the global maximum under partially shaded conditions, and the array output efficiency can be improved.

DNA barcoding and phylogenetic analysis of midges belonging to Culicoides (Diptera: Ceratopogonidae) subgenus Hoffmania in Yunnan, China

Duan Ying Liang,Bellis Glenn,Yang Zhen Xing,Li Zhan Hong,Liu Bing Gang,Li Le 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.4

DNA barcodes obtained from cytochrome c oxidase subunit 1 (cox1) offer a fast and easy way to identify a range of biological organisms. Culicoides (Diptera: Ceratopogonidae) are a group of small, blood sucking midges whose species are the vectors for some arboviruses, such as bluetongue virus, African horse sickness virus, epizootic hemorrhagic disease virus and equine encephalosis virus. Identification of these small insects is difficult so constructing DNA barcode libraries for species present in certain areas is helpful to clarify the taxonomy and assist non-specialist workers to identify species. In this study, we analysed specimens belonging to C. subgenus Hoffmania collected from 12 towns of Yunnan Province, China. Specimens were identified by morphology and processed to construct DNA barcodes. A total of 185 specimens referable to 6 morphological species were pro cessed for cox1 and 28S rRNA sequencing. The resulting 185 cox1 sequences were assigned to 13 barcode index numbers (BINs) which include 9 novel BINs. Molecular and morphological evidence was used to support the transfer of 4 species previously assigned to C. subg. Avaritia into C. subg. Hoffmania. Molecular analysis revealed the presence of 7 potential cryptic species within C. innoxius, three within C. liui and two within C. insignipennis.

Dual-Algorithm Maximum Power Point Tracking Control Method for Photovoltaic Systems based on Grey Wolf Optimization and Golden-Section Optimization

Ji-Ying Shi,Deng-Yu Zhang,Le-Tao Ling,Fei Xue,Ya-Jing Li,Zi-Jian Qin,Ting Yang 전력전자학회 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.3

This paper presents a dual-algorithm search method (GWO-GSO) combining grey wolf optimization (GWO) and golden-section optimization (GSO) to realize maximum power point tracking (MPPT) for photovoltaic (PV) systems. First, a modified grey wolf optimization (MGWO) is activated for the global search. In conventional GWO, wolf leaders possess the same impact on decision-making. In this paper, the decision weights of wolf leaders are automatically adjusted with hunting progression, which is conducive to accelerating hunting. At the later stage, the algorithm is switched to GSO for the local search, which play a critical role in avoiding unnecessary search and reducing the tracking time. Additionally, a novel restart judgment based on the quasi-slope of the power-voltage curve is introduced to enhance the reliability of MPPT systems. Simulation and experiment results demonstrate that the proposed algorithm can track the global maximum power point (MPP) swiftly and reliably with higher accuracy under various conditions.

Azo-based small molecular hypoxia responsive theranostic for tumor-specific imaging and therapy

Zhou, Ying,Maiti, Mrinmoy,Sharma, Amit,Won, Miae,Yu, Le,Miao, Lan Xi,Shin, Jinwoo,Podder, Arup,Bobba, Kondapa Naidu,Han, Jiyou,Bhuniya, Sankarprasad,Kim, Jong Seung Elsevier 2018 Journal of controlled release Vol.288 No.-

<P><B>Abstract</B></P> <P>We report herein, an azo-derivative (<B>AzP1</B>) of FDA approved antineoplastic drug SN-38 (irinotecan analogue) as a theranostic agent with a potential for both tumor hypoxia-specific activation and therapy. The theranostic <B>AzP1</B> was found to be stable within a biologically relevant pH scale and was chemically inert towards other competitive biological analytes. However, upon treatment with rat-liver microsomes, <B>AzP1</B> showed a self-calibrated fluorescence enhancement at λ<SUB>em</SUB> = 560 nm. The cytotoxicity profile of <B>AzP1</B> was tested in various cancer lines. Under hypoxic conditions, prodrug <B>AzP1</B> exhibited activation to release the parent drug (SN-38) and enhanced cytotoxicity in cancer cells with concomitant fluorescence enhancement at 560 nm, which served to monitor both the drug activation and tracing purposes. The therapeutic potential of <B>AzP1</B> for both tumor-specific activation and suppression of tumor weights was validated in xenograft mouse model. Collectively, the synthetic ease and hypoxia-sensitive activation along with promising therapeutic properties highlight the potential of theranostic <B>AzPI</B> in future cancer treatment programs.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>